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Displaying drugs 1526 - 1550 of 2396 in total

Trotabresib

Trotabresib is an oral, potent, and reversible inhibitor of the epigenetic target bromodomain and extra-terminal (BET) proteins.
Investigational
Matched Synonyms: … 1(2h)-isoquinolinone, 4-(2-(cyclopropylmethoxy)-5-(methylsulfonyl)phenyl)-2-methyl- …
Matched Description: … Trotabresib is an oral, potent, and reversible inhibitor of the epigenetic target bromodomain and extra-terminal …

Dalpiciclib

Investigational
Matched Synonyms: … Pyrido(2,3-d)pyrimidin-7(8h)-one, 6-acetyl-8-cyclopentyl-5-methyl-2-((5-(4-piperidinyl)-2-pyridinyl)amino …
Matched Iupac: … 6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperidin-4-yl)pyridin-2-yl]amino}-7H,8H-pyrido[2,3-d]pyrimidin …

1-(3-fluoro-4-(7-(5-methyl-1H-imidazol-2-yl)-1-oxo-2,3-dihydro-1H-isoindo-1-4-yl)-phenyl)-3-(3-trifluoromethyl-phenyl)-urea

Investigational
Matched Synonyms: … Urea, n-(4-(2,3-dihydro-7-(5-methyl-1h-imidazol-2-yl)-1-oxo-1h-isoindol-4-yl)-3-fluorophenyl)-n'-(3-( …
Matched Name: … 1-(3-fluoro-4-(7-(5-methyl-1H-imidazol-2-yl)-1-oxo-2,3-dihydro-1H-isoindo-1-4-yl)-phenyl)-3-(3-trifluoromethyl-phenyl …
Matched Iupac: … 3-{3-fluoro-4-[7-(4-methyl-1H-imidazol-2-yl)-1-oxo-2,3-dihydro-1H-isoindol-4-yl]phenyl}-1-[3-(trifluoromethyl …

Bromhexine

Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased mucus secretion. It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing and reducing cough. It was introduced into the market in 1963, and is widely available as...
Approved
Matched Synonyms: … N-cyclohexyl-N-methyl-(2-amino-3,5-dibrombenzyl)amine …
Matched Iupac: … 2,4-dibromo-6-{[cyclohexyl(methyl)amino]methyl}aniline …
Matched Description: … [A233240] Recently, bromhexine and its metabolite [ambroxol] have garnered interest for the potential ... and reducing cough. ... Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased …
Matched Categories: … Cough and Cold Preparations …
Matched Products: … DISOL FORTE ELIXIR 8 MG/5ML …

Sildenafil

In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614]. The result of doing so allows cGMP present in both the penis and pulmonary vasculature to...
Approved
Investigational
Matched Synonyms: … 1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl) …
Matched Iupac: … 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1H,4H,7H-pyrazolo[4,3-d]pyrimidin …
Matched Description: … effective treatment for erectile dysfunction and since its formal approval for medical use in the public ... it to grow in size and become erect and rigid [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614 ... The result of doing so allows cGMP present in both the penis and pulmonary vasculature to elicit smooth …
Matched Products: … Sildenafil for Oral Suspension …

Pantoprazole

Pantoprazole is a first-generation proton pump inhibitor (PPI) used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison (ZE) Syndrome. It can also be...
Approved
Matched Description: … antibiotics including [amoxicillin], [clarithromycin], and [metronidazole], for example. ... from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including ... and bone fractures later in life. …
Matched Categories: … Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) ... Drugs for Acid Related Disorders ... Alimentary Tract and Metabolism ... pantoprazole, amoxicillin and clarithromycin ... pantoprazole, amoxicillin, clarithromycin and metronidazole …
Matched Products: … panpriva 40mg Powder for Solution for Injection ... Pantoprazole NORMON powder for solution for injection 40mg ... ALPANZOLE POWDER FOR SOLUTION FOR INJECTION 40 MG/VIAL …

2-amino-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]benzamide

Experimental
Matched Name: … 2-amino-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]benzamide …
Matched Iupac: … 2-amino-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]benzamide …

(3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(benzylsulfanyl)methyl]pyrrolidin-3-ol

Experimental
Matched Name: … (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(benzylsulfanyl)methyl]pyrrolidin-3-ol …
Matched Iupac: … (3R,4S)-1-({4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl}methyl)-4-[(benzylsulfanyl)methyl]pyrrolidin-3-ol …

N-PYRIDOXYL-2-METHYL-L-GLUTAMIC ACID-5'-MONOPHOSPHATE

Experimental
Matched Name: … N-PYRIDOXYL-2-METHYL-L-GLUTAMIC ACID-5'-MONOPHOSPHATE …
Matched Iupac: … (2S)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-2-methylpentanedioic …

1-METHYL-3-PHENYL-1H-PYRAZOL-5-YLSULFAMIC ACID

Experimental
Matched Name: … 1-METHYL-3-PHENYL-1H-PYRAZOL-5-YLSULFAMIC ACID …
Matched Iupac: … N-(1-methyl-3-phenyl-1H-pyrazol-5-yl)sulfamic acid …

(2S)-2-{[HYDROXY(4-IODOBENZYL)PHOSPHORYL]METHYL}PENTANEDIOIC ACID

Experimental
Matched Name: … (2S)-2-{[HYDROXY(4-IODOBENZYL)PHOSPHORYL]METHYL}PENTANEDIOIC ACID …
Matched Iupac: … (2S)-2-({hydroxy[(4-iodophenyl)methyl]phosphoryl}methyl)pentanedioic acid …

3-{(R)-(Dihydroxyboryl)[(2-thienylacetyl)amino]methyl}benzoic acid

Experimental
Matched Name: … 3-{(R)-(Dihydroxyboryl)[(2-thienylacetyl)amino]methyl}benzoic acid …
Matched Iupac: … 3-[(R)-(dihydroxyboranyl)[2-(thiophen-2-yl)acetamido]methyl]benzoic acid …

Pentamidine

Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of pneumocystis pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
Approved
Investigational
Matched Description: … It may cause diabetes mellitus, central nervous system damage, and other toxic effects. ... Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in …
Matched Categories: … Antibiotics for Pneumocystis Pneumonia ... Agents Against Leishmaniasis and Trypanosomiasis ... Antiparasitic Products, Insecticides and Repellents …
Matched Products: … Pentamidine Isetionate for Injection BP ... DBL™ PENTAMIDINE ISETHIONATE FOR INJECTION BP 300mg ... DBL PENTAMIDINE ISETHIONATE FOR INJECTION BP 300 mg/vial …

Fobrepodacin

Investigational
Matched Synonyms: … N-ethyl-n'-(6-fluoro-5-(2-(1-methyl-1-(phosphonooxy)ethyl)-5-pyrimidinyl)-7-((2r)-tetrahydro-2-furanyl ... Urea, n-ethyl-n'-(6-fluoro-5-(2-(1-methyl-1-(phosphonooxy)ethyl)-5-pyrimidinyl)-7-((2r)-tetrahydro-2- …

Aztreonam

A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.
Approved
Matched Synonyms: … (Z,)-2-((((2-Amino-4-thiazolyl)(((2S,3S,)-2-methyl-4-oxo-1-sulfo-3-azetidinyl)carbamoyl)methylene)amino ... 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl) -2- {[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino} -2- oxoethylidene …
Matched Iupac: … (2S,3S)-3-[(2Z)-2-(2-azaniumyl-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetamido]-2-methyl …
Matched Description: … , bladder, and kidneys. ... It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … AZACTAM FOR INJECTION 1 g/vial …

Cholestyramine

Cholestyramine or colestyramine is a bile acid sequestrant. Bile acid sequestrants are polymeric compounds which serve as ion exchange resins. Cholestyramine resin is quite hydrophilic, but insoluble in water.
Approved
Investigational
Matched Categories: … Hypolipidemic Agents Indicated for Hyperlipidemia ... Non-statin Hypolipidemic Agents Indicated for Hyperlipidemia …
Matched Products: … Cholestyramine Powder for Suspension ... Cholestyramine for Oral Suspension ... PHL-cholestyramine Powder for Suspension 400gm/can …

Iodine

Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds. Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.[A3413,A192153,A192156,A192159]
Approved
Investigational
Matched Description: … Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may ... Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer. …
Matched Mixtures name: … For-2 ... PEDIVITE FORTE CAPSULE ... Doctor's Choice Brand for Men …
Matched Categories: … Diet, Food, and Nutrition ... Antiseptics and Disinfectants ... Herbs and Natural Products …
Matched Products: … XENETIX 350-50ML SOLN FOR INTRAVASCULAR INJ ... XENETIX 300-50ML SOLN FOR INTRAVASCULAR INJ ... XENETIX 350-100ML SOLN FOR INTRAVASCULAR INJ …

Chlorzoxazone

A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
Approved
Matched International brands: … Strifon Forte DSC …
Matched Description: … is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and …
Matched Mixtures name: … Extra Strength Tylenol Aches and Strains ... Parafon Forte ... Acetazone Forte …
Matched Categories: … Benzoxazoles and derivatives ... Oxazol, Thiazine, and Triazine Derivatives …
Matched Products: … Parafon Forte ... Parafon Forte DSC ... PARAFLEX FORTE TABLET 500 MG, 20 ADET …

Amiodarone

Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings. Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpatient setting for atrial fibrillation. Because of its ability to cause serious toxicity and possibly death, amiodarone...
Approved
Investigational
Matched Description: … used off-label in the outpatient and inpatient setting for atrial fibrillation. ... Because of its ability to cause serious toxicity and possibly death, amiodarone use should be reserved ... for its approved indications, according to prescribing information. …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Matched Products: … DIOLUX CONCENTRATE FOR SOLUTION FOR INJECTION 50MG/ML ... Amiodarone for Injection 50mg/ml ... Amiodarone Hydrochloride for Injection …

Gadoteric acid

Gadoteric acid, commonly used in the salt form gadoterate meglumine, is a macrocyclic, ionic gadolinium-based contrast agent (GBCA). It is composed of the organic acid DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) used for its chelating properties, and gadolinium (Gd3+). Gadoterate meglumine has one of the highest thermodynamic stability, apparent stability, and kinetic stability,...
Approved
Matched Description: … tissues in adult and pediatric patients (2 years of age and older) to detect and visualize areas with ... Gadoteric acid, commonly used in the salt form gadoterate meglumine, is a macrocyclic, ionic gadolinium-based ... is composed of the organic acid DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) used for …
Matched Products: … DOTAGRAF SOLUTION FOR INJECTION 0.5 MMOL/ML ... CLARISCAN SOLUTION FOR INJECTION IN VIAL 0.5 MMOL/ML ... CLARISCAN SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 0.5 MMOL/ML …

Dulaglutide

Dulaglutide, marketed by Eli Lilly as Trulicity, is a once-weekly subcutaneous glucagon-like peptide-1 (GLP-1) receptor agonist designed using recombinant DNA technology; it has been approved as an adjunct therapy to diet and exercise in the management of 2 diabetes (T2DM). Dulaglutide was initially approved by the FDA in 2014, and...
Approved
Investigational
Matched Description: … [A236070] Dulaglutide was initially approved by the FDA in 2014, and in February 2020 was approved for ... use in patients with T2DM and multiple cardiovascular risk factors for the prevention of cardiovascular ... agonist designed using recombinant DNA technology; it has been approved as an adjunct therapy to diet and …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Trulicity 1.5mg solution for injection in pre-filled pen ... Trulicity 0.75mg solution for injection in pre-filled pen …

Peginterferon alfa-2a

Peginterferon alfa-2a is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Investigational
Matched Description: … 36% for genotype 1 and 59% for genotypes 2-6 after 48 weeks of treatment. ... development of endocrine and autoimmune disorders, retinopathies, cardiovascular and neuropsychiatric ... -2a for the treatment of Hepatitis C [A19593]. …
Matched Categories: … Treatments for Hepatitis C ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … PEGASYS PRE-FILLED SYRINGE FOR INJECTION 180 mcg/0.5 ml ... PEGASYS PRE-FILLED SYRINGE FOR INJECTION 135 mcg/0.5 ml …

RU85053

Experimental
Matched Synonyms: … 5-[(2S)-2-Acetamido-3-oxo-3-[[(3S)-2-oxo-1-[(4-phenylphenyl)methyl]azepan-3-yl]amino]propyl]-2-(carboxymethyl …
Matched Iupac: … 5-[(2S)-2-{[(3S)-1-({[1,1'-biphenyl]-4-yl}methyl)-2-oxoazepan-3-yl]carbamoyl}-2-acetamidoethyl]-2-(carboxymethyl …

Simurosertib

Simurosertib is under investigation in clinical trial NCT03261947 (A Study to Evaluate the Safety, Tolerability, and Activity of TAK-931 in Participants With Metastatic Pancreatic Cancer, Metastatic Colorectal Cancer, and Other Advanced Solid Tumors).
Investigational
Matched Synonyms: … 2-[(2S)-1-azabicyclo[2.2.2]oct-2-yl]-6-(3-methyl-1H-pyrazol-4-yl)thieno[3,2-d]pyrimidin-4(3H)-one …
Matched Iupac: … 2-[(2S)-1-azabicyclo[2.2.2]octan-2-yl]-6-(3-methyl-1H-pyrazol-4-yl)-3H,4H-thieno[3,2-d]pyrimidin-4-one …
Matched Description: … is under investigation in clinical trial NCT03261947 (A Study to Evaluate the Safety, Tolerability, and ... Activity of TAK-931 in Participants With Metastatic Pancreatic Cancer, Metastatic Colorectal Cancer, and …

p-Toluenesulfonamide

Investigational
Matched Synonyms: … Benzenesulfonamide, 4-methyl- …
Displaying drugs 1526 - 1550 of 2396 in total