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Displaying drugs 1 - 25 of 15561 in total
Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least two of which are glycosylated. This differs from recombinant alpha interferons, which are individual non-glycosylated proteins produced from individual alpha interferon genes.
Approved
Investigational
Matched Synonyms: … Interferon alpha-n1 (INS) ... Interferon alfa-n1 …
Matched Name: … Interferon alfa-n1 …
Matched Description: … from individual alpha interferon genes. ... Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least ... This differs from recombinant alpha interferons, which are individual non-glycosylated proteins produced …
Matched Categories: … Interferon Type I ... interferon alfa-n1 ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). A type I interferon consisting of 165 amino acid residues with arginine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent.
Approved
Matched Synonyms: … Interferon alpha-2B ... rIFN-alpha-2b ... Interferon alfa-2b
Matched Name: … Interferon alfa-2b
Matched Description: … Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). ... This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes ... A type I interferon consisting of 165 amino acid residues with arginine in position 23. …
Matched Mixtures name: … Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules) …
Matched Categories: … interferon alfa-2b ... Interferon alpha ... Interferon-alpha ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis (MS), and was initially approved by the FDA in 1992. Multiple Sclerosis is a devastating neurodegenerative disease that is usually progressive and significantly debilitating with a profound impact on the quality of life. Interferon...
Approved
Investigational
Matched Synonyms: … Interferon beta ... Interferon-beta ... Fibroblast interferon
Matched Name: … Human interferon beta …
Matched Description: … (MS), and was initially approved by the FDA in 1992. ... results from infection with the novel 2019 SARS-CoV-2 virus. ... It is therefore a potential drug candidate for SARS-CoV-2 based on viral genetic similarity. …
Matched Categories: … Interferon Type I ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Purified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms including 2a, 2b and 2c). 166 residues, some are glycosylated (MW range from 16 kD to 27 kD).
Approved
Investigational
Matched Synonyms: … Interferon alfa-n3 …
Matched Name: … Interferon alfa-n3 …
Matched Description: … including 2a, 2b and 2c). 166 residues, some are glycosylated (MW range from 16 kD to 27 kD). ... Purified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms …
Matched Categories: … Interferon alpha ... Interferon-alpha ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Interferon Type I …
Approved
Experimental
Matched Synonyms: … Alpha Arbutin ... alpha-D-Glucopyranoside, 4-hydroxyphenyl …
Matched Name: … alpha-Arbutin …
Matched Iupac: … (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol …
Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the...
Approved
Nutraceutical
Vet approved
Matched Synonyms: … D-alpha tocoferil acetate ... alpha-tocopheryl acetate, D- ... D-alpha tocopheryl acetate …
Matched Name: … D-alpha-Tocopherol acetate …
Matched Iupac: … (2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-yl acetate …
Matched Description: … is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability ... In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer ... At the moment however, there exists a lack of formal data and evidence to support any such additional …
Matched Mixtures name: … Multi Vitamin and Mineral vitamin ... Iron With Vitamins C and E - Tab ... Vita Vim Multivitamins and Minerals Tab …
Matched Categories: … Diet, Food, and Nutrition ... Heterocyclic Compounds, 2-Ring …
Alpha-dihydroergocryptine is usually referred to the mixture of the alpha and beta dihydroergocryptine. These two compounds are differentiated in the position of a methyl group. This structural difference is due to a proteinogenic amino acid replacement from leucine to isoleucine. Both compounds are hydrogenated ergot derivatives. Alpha-dihydroergocryptine approved drug product...
Approved
Matched Synonyms: … alpha-Dihydroergocriptine …
Matched Name: … Dihydro-alpha-ergocryptine …
Matched Iupac: … (2R,4R,7R)-N-[(1S,2S,4R,7S)-2-hydroxy-7-(2-methylpropyl)-5,8-dioxo-4-(propan-2-yl)-3-oxa-6,9-diazatricyclo …
Matched Description: … Alpha-dihydroergocryptine is usually referred to the mixture of the alpha and beta dihydroergocryptine ... Alpha-dihydroergocryptine approved drug product is as a part of an ergoloid mixture. …
Matched Salts name: … Dihydro-alpha-ergocryptine mesylate …
Approved
Experimental
Matched Synonyms: … DL-alpha-tocopheryl acetate ... all-rac-alpha-tocopheryl acetate …
Matched Name: … DL-alpha tocopheryl acetate …
Matched Iupac: … 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-1-benzopyran-6-yl acetate …
Matched Mixtures name: … Stress B Complex With C and E Tab ... Stress B Complex With C, E and Iron Tab ... Cavan Alpha
Multiple Sclerosis (MS) is a chronic and inflammatory autoimmune disease of the central nervous system, disrupting communication between the brain and other parts of the body. Most patients diagnosed with this illness experience their initial disease symptoms between the age of 20 to 40, often the most productive years of...
Approved
Matched Synonyms: … Polyethylene glycol-interferon beta-1a …
Matched Description: … [A176474,L5792] Peginterferon beta-1a is an interferon therapy used for the management of relapsing ... [L31428] Currently, it is the only approved pegylated interferon for the management of MS with an proven ... , disrupting communication between the brain and other parts of the body. …
Matched Categories: … Interferon-beta ... Interferon Type I ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … PLEGRİDY 125 MCG/0.5 ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 2 ADET …
Polycythemia vera (PV) is the most common Philadelphia chromosome-negative myeloproliferative neoplasm (MPN), characterized by increased hematocrit and platelet/leukocyte counts, an increased risk for hemorrhage and thromboembolic events, and a long-term propensity for myelofibrosis and leukemia.[A242000, A242005] Interferon alfa-2b has been used for decades to treat PV but requires frequent dosing...
Approved
Investigational
Matched Synonyms: … Pegylated proline interferon alpha-2b ... Pegylated proline-interferon alpha-2b ... Ropeginterferon alfa-2b
Matched Name: … Ropeginterferon alfa-2b
Matched Description: … [A242005] Ropeginterferon alfa-2b is a next-generation mono-pegylated type I interferon produced from ... [A242000, A242005] [Interferon alfa-2b] has been used for decades to treat PV but requires frequent dosing ... proline-IFN-α-2b in _Escherichia coli_ that has high tolerability and a long half-life. …
Matched Categories: … ropeginterferon alfa-2b ... Antineoplastic and Immunomodulating Agents …
Agalsidase alfa is a recombinant human α-galactosidase A similar to agalsidase beta. While patients generally do not experience a clinically significant difference in outcomes between the two drugs, some patients may experience greater benefit with agalsidase beta.[A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa,...
Approved
Matched Synonyms: … Agalsidase alpha ... alpha-galactisidase ... alpha-D-galactosidase …
Matched Categories: … alpha-Galactosidase, antagonists & inhibitors ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Bisabolol, or more formally α-(−)-bisabolol or also known as levomenol, (-)-alpha-Bisabolol is found in fats and oils. (-)-alpha-Bisabolol is isolated from essential oil of Matricaria chamomilla (German chamomile) (-)-alpha-Bisabolol belongs to the family of Sesquiterpenes. These are terpenes with three consecutive isoprene units.
Approved
Experimental
Matched Synonyms: … alpha-bisabolol ... (-)-alpha-Bisabolol ... alpha-(-)-bisabolol …
Matched Iupac: … (2S)-6-methyl-2-[(1S)-4-methylcyclohex-3-en-1-yl]hept-5-en-2-ol …
Matched Description: … in fats and oils. (-)-alpha-Bisabolol is isolated from essential oil of Matricaria chamomilla (German ... chamomile) (-)-alpha-Bisabolol belongs to the family of Sesquiterpenes. ... Bisabolol, or more formally α-(−)-bisabolol or also known as levomenol, (-)-alpha-Bisabolol is found …
Cardioactive derivative of lanatoside A or of digitoxin used for fast digitalization in congestive heart failure.
Approved
Matched Synonyms: … Acetyl-digitoxin-alpha ... alpha-Acetyldigitoxin ... alpha-Acetylgitaloxin …
Matched Iupac: … methyloxan-3-yl]oxy}-4-hydroxy-2-methyloxan-3-yl]oxy}-3-hydroxy-2-methyloxan-4-yl acetate ... 11a-dimethyl-1-(5-oxo-2,5-dihydrofuran-3-yl)-hexadecahydro-1H-cyclopenta[a]phenanthren-7-yl]oxy}-4-hydroxy-2- …
Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis. It is marketed under the name Aubagio® and is indicated for the treatment of multiple sclerosis, specifically relapsing forms. The FDA label states an important warning about the risk of hepatoxicity and...
Approved
Matched Synonyms: … (Z)-2-cyano-alpha,alpha,alpha-trifluoro-3-hydroxy-p-crotonotoluidide …
Matched Iupac: … (2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide …
Matched Description: … Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting ... The FDA label states an important warning about the risk of hepatoxicity and teratogenicity for patients ... It is marketed under the name Aubagio® and is indicated for the treatment of multiple sclerosis, specifically …
Matched Categories: … Leflunomide and metabolite ... Antineoplastic and Immunomodulating Agents …
Phentermine is a sympathomimetic amine anorectic agent and it was introduced in 1959 as part of an anti-obesity combination drug.[A174361, A174364] It is chemically related to amphetamine and it is commonly referred to as an atypical amphetamine. Phentermine has not been reported an addictive potential which allows this agent to...
Approved
Illicit
Matched Synonyms: … alpha,alpha-Dimethylphenethylamine …
Matched Iupac: … 2-methyl-1-phenylpropan-2-amine …
Matched Description: … Phentermine is a sympathomimetic amine anorectic agent and it was introduced in 1959 as part of an anti-obesity ... [A174361, A174364] It is chemically related to amphetamine and it is commonly referred to as an atypical ... [A174367] Phentermine was FDA approved for short-term weight management in 1959 and it became widely …
Matched Categories: … Alimentary Tract and Metabolism ... phentermine and topiramate …
Methyldopa, or α-methyldopa, is a centrally acting sympatholytic agent and an antihypertensive agent. It is an analog of DOPA (3,4‐hydroxyphenylanine), and it is a prodrug, meaning that the drug requires biotransformation to an active metabolite for therapeutic effects. Methyldopa works by binding to alpha(α)-2 adrenergic receptors as an agonist, leading...
Approved
Matched Synonyms: … Alpha medopa ... alpha-Methyl dopa ... alpha-methyl-L-dopa …
Matched Iupac: … (2S)-2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid …
Matched Description: … Methyldopa works by binding to alpha(α)-2 adrenergic receptors as an agonist, leading to the inhibition ... of adrenergic neuronal outflow and reduction of vasoconstrictor adrenergic signals. ... Methyldopa, or α-methyldopa, is a centrally acting sympatholytic agent and an antihypertensive agent. …
Matched Mixtures name: … Methyldopa and Hydrochlorothiazide ... Methyldopa and Hydrochlorothiazide ... Methyldopa and Hydrochlorothiazide …
Matched Categories: … Adrenergic alpha-2 Receptor Agonists ... Central alpha-2 Adrenergic Agonist ... Amino Acids, Peptides, and Proteins ... Adrenergic alpha-Agonists ... Central Alpha-agonists …
Methylprednisone has been used in trials studying the treatment of Leukemia, Rheumatoid Arthritis, Renal Transplantation, Kidney Transplantation, and Acute Lymphocytic Leukemia, among others.
Approved
Investigational
Matched Synonyms: … 6-alpha-methylprednisone …
Matched Iupac: … (1R,3aS,3bS,5S,9aR,9bS,11aS)-1-hydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H, …
Matched Description: … studying the treatment of Leukemia, Rheumatoid Arthritis, Renal Transplantation, Kidney Transplantation, and
Overactive bladder (OAB) is a common condition negatively impacting the lives of millions of patients worldwide. Due to its urinary symptoms that include nocturia, urgency, and frequency, this condition causes social embarrassment and a poor quality of life.[A185996,A185999] Oxybutynin, also marketed as Ditropan XL, is an anticholinergic medication used for...
Approved
Investigational
Matched Synonyms: … 4-Diethylamino-2-butinyl alpha-cyclohexylmandelat ... 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate ... 4-(Diethylamino)-2-butynyl alpha-phenylcyclohexaneglycolic acid ester …
Matched Iupac: … 4-(diethylamino)but-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate …
Matched Description: … embarrassment and a poor quality of life. ... Due to its urinary symptoms that include nocturia, urgency, and frequency, this condition causes social ... used for the relief of overactive bladder symptoms that has been optimized for high levels of safety and
Matched Salts cas: … 1508-65-2
Matched Categories: … Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Bromocriptine mesylate is a semisynthetic ergot alkaloid derivative with potent dopaminergic activity. It inhibits prolactin secretion and may be used to treat dysfunctions associated with hyperprolactinemia. Bromocriptine is also indicated for the management of signs and symptoms of Parkinsonian Syndrome, as well as the treatment of acromegaly. Bromocriptine has been...
Approved
Investigational
Withdrawn
Matched Synonyms: … 2-Bromo-alpha-ergocryptine ... 2-Bromo-alpha-ergokryptin ... 2-Bromo-alpha-ergokryptine …
Matched Iupac: … (4R,7R)-10-bromo-N-[(1S,2S,4R,7S)-2-hydroxy-7-(2-methylpropyl)-5,8-dioxo-4-(propan-2-yl)-3-oxa-6,9-diazatricyclo …
Matched Description: … Bromocriptine is also indicated for the management of signs and symptoms of Parkinsonian Syndrome, as ... It inhibits prolactin secretion and may be used to treat dysfunctions associated with hyperprolactinemia ... Bromocriptine has been associated with pulmonary fibrosis, and can also cause sustained suppression of …
Matched Categories: … Adrenergic alpha-2 Receptor Agonists ... Ergot Alkaloids and Derivatives ... Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Adrenergic alpha-Agonists …
Levonordefrin acts as a topical nasal decongestant and vasoconstrictor, most often used in dentistry.
Approved
Matched Synonyms: … alpha-Methylnoradrenaline ... L-alpha-methylnoradrenaline …
Matched Iupac: … 4-[(1R,2S)-2-amino-1-hydroxypropyl]benzene-1,2-diol …
Matched Description: … Levonordefrin acts as a topical nasal decongestant and vasoconstrictor, most often used in dentistry. …
Matched Mixtures name: … Mepivacaine Hydrochloride and Levonordefrin ... Scandonest 2% L ... Isocaine HCl Inj 2% …
Matched Categories: … Epinephrine and similars …
Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. It is a complement inhibitor that works to prevent the activation of C5, which is a complement protein involved in the innate immune system to initiate inflammatory responses. On October 17, 2023, zilucoplan gained its first FDA approval for the treatment of...
Approved
Matched Synonyms: … -ASPARTYL-3-METHYL-L-VALYL-L-TYROSYL-3-(1H-PYRROLO(2,3-B)PYRIDIN-3-YL)-L-ALANYL-L-.ALPHA. ... POLY(OXY-1,2-ETHANEDIYL), .ALPHA.-(2-(((4S)-4-CARBOXY-1-OXO-4-(1-OXOHEXADECYL)BUTYL)AMINO)ETHYL)-.OMEGA ... -GLUTAMYL-L-TYROSYL-L-PROLYL-(2S)-2-CYCLOHEXYLGLYCYL-N6-(3 …
Matched Iupac: … ]-3-(4-hydroxyphenyl)propanamido]-3-{1H-pyrrolo[2,3-b]pyridin-3-yl}propanamido]-4-carboxybutanamido]- ... (2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{1-[(2S,5S,8S,11S,14S,22S)-11 ... -benzyl-8-(3-carbamimidamidopropyl)-5-(2-carboxyethyl)-22-acetamido-3,6,9,12,16,23-hexaoxo-2-(propan- ... 3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-2-cyclohexylacetamido]-6-{1-[(4S)-4-carboxy-4 ... 2-yl)-1,4,7,10,13,17-hexaazacyclotricosan-14-yl]-N-methylformamido}-3-carboxypropanamido]-3,3-dimethylbutanamido …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Humanized IgG1 kappa isotype monoclonal antibody that binds to human CD11a. Efalizumab has a molecular weight of approximately 150 kilodaltons and is produced in a Chinese hamster ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin. The FDA approved efalizumab in 2003. It was later withdrawn...
Approved
Investigational
Withdrawn
Matched Synonyms: … antiCD11 alpha
Matched Description: … Efalizumab has a molecular weight of approximately 150 kilodaltons and is produced in a Chinese hamster …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Mesuximide (or methsuximide) is an anticonvulsant medication. It is sold by Pfizer under the name Petinutin.
Approved
Matched Synonyms: … N,2-Dimethyl-2-phenylsuccinimide ... alpha-Methyl-alpha-phenyl N-methyl succinimide ... N-methyl-alpha-methyl-alpha-phenylsuccinimide …
Recombinant human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each with N-and O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ASN-30, SER-121, SER-127, SER-132 and SER-138 (on beta subunit). The primary structure of the alpha-chain of r-hCG is identical...
Approved
Matched Synonyms: … Choriogonadotropin alpha
Matched Description: … Recombinant human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each ... with N-and O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ... and LH. …
Matched Categories: … Gonadotropins and Antigonadotropins ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System …
Bifonazole is an azole antifungal drug.
Approved
Investigational
Matched Synonyms: … (+-)-1-(p,alpha-Diphenylbenzyl)imidazole ... 1-(p,alpha-Diphenylbenzyl)imidazole ... 1-(alpha-(4-Biphenylyl)benzyl)imidazole …
Matched Categories: … Imidazole and Triazole Derivatives …
Displaying drugs 1 - 25 of 15561 in total