Displaying drugs 226 - 250 of 3048 in total
Eurotium amstelodami
Eurotium amstelodami allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, aspergillus amsterdami …
Benzocaine
Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. It is commonly used for local anesthesia in many over the counter products.[L32454,L32459,L32464] Benzocaine was first used for local anesthesia in dentistry.
Approved
Investigational
Matched Synonyms: … 4-aminobenzoic acid ethyl ester …
Matched Description: … Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and …
Matched Mixtures name: … Benzocaine, Menthol, Zinc Chloride ... Benzocaine, Menthol, Zinc Chloride ... Benzocaine, Menthol, Zinc Chloride …
Matched Salts name: … Benzocaine hydrochloride …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Antipruritics and Local Anesthetics ... Acids, Carbocyclic ... Carboxylic Acids ... Esters of Aminobenzoic Acid …
Matched Products: … Bite and Sting relief ... Sting and Bite ... Medicaine Sting and Bite …
Matched Description: … Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and …
Matched Mixtures name: … Benzocaine, Menthol, Zinc Chloride ... Benzocaine, Menthol, Zinc Chloride ... Benzocaine, Menthol, Zinc Chloride …
Matched Salts name: … Benzocaine hydrochloride …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Antipruritics and Local Anesthetics ... Acids, Carbocyclic ... Carboxylic Acids ... Esters of Aminobenzoic Acid …
Matched Products: … Bite and Sting relief ... Sting and Bite ... Medicaine Sting and Bite …
Prasterone sulfate
DHEA sulfate is the major steroid of the fetal adrenal. DHEA-S is the principal adrenal androgen and is secreted together with cortisol under the control of ACTH and prolactin. DHEA-S is elevated with hyperprolactinemia.
Investigational
Matched Synonyms: … Androst-5-en-17-on-3beta-yl sulfuric acid ... DHEA sulfate ... DHEA sulphate …
Matched Name: … Prasterone sulfate …
Matched Iupac: … -1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-yl]oxidanesulfonic acid …
Matched Description: … DHEA sulfate is the major steroid of the fetal adrenal. ... ACTH and prolactin. ... DHEA-S is the principal adrenal androgen and is secreted together with cortisol under the control of …
Matched Salts name: … Prasterone sodium sulfate anhydrous …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Name: … Prasterone sulfate …
Matched Iupac: … -1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-yl]oxidanesulfonic acid …
Matched Description: … DHEA sulfate is the major steroid of the fetal adrenal. ... ACTH and prolactin. ... DHEA-S is the principal adrenal androgen and is secreted together with cortisol under the control of …
Matched Salts name: … Prasterone sodium sulfate anhydrous …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Capsicum
Capsicum (Chili pepper) allergenic extract is used in allergenic testing.
Approved
Matched Mixtures name: … Zaxs Aches and Pain …
Matched Products: … SinolM Fast Allergy and Sinus Relief All-Natural Nasal …
Matched Products: … SinolM Fast Allergy and Sinus Relief All-Natural Nasal …
Chlorine dioxide
Chlorine Dioxide has been used in trials studying the treatment of Halitosis.
Investigational
Matched Products: … Disinfectant and Sanitizer …
Coal tar
Coal tar is a brown or black liquid of extremely high viscosity. Coal tar is among the by-products when coal is carbonized to make coke or gasified to make coal gas. Coal tars are complex and variable mixtures of phenols, polycyclic aromatic hydrocarbons (PAHs), and heterocyclic compounds.
It has been...
Approved
Matched Description: … and eczema. ... Coal tars are complex and variable mixtures of phenols, polycyclic aromatic hydrocarbons (PAHs), and ... It has been indicated for local relief of itching, dryness, and irritation caused by psoriasis, seborrhea …
Matched Mixtures name: … Pete and Pedro ... PREPARED COAL TAR 5% ET SALICYLIC ACID 2% OINTMENT ... Clobetasol Propionate 0.05% / Coal Tar 8% / Salicylic Acid 6% …
Matched Products: … Skin and Scalp Body ... Skin and scalp ... Assured T And Plus …
Matched Mixtures name: … Pete and Pedro ... PREPARED COAL TAR 5% ET SALICYLIC ACID 2% OINTMENT ... Clobetasol Propionate 0.05% / Coal Tar 8% / Salicylic Acid 6% …
Matched Products: … Skin and Scalp Body ... Skin and scalp ... Assured T And Plus …
Dermatan sulfate
Experimental
Matched Synonyms: … Chondroitinsulfuric acid type B ... Chondroitin sulfate B ... Dermatan 4-sulfate …
Matched Name: … Dermatan sulfate …
Matched Salts name: … Dermatan sulfate sodium …
Matched Categories: … Blood and Blood Forming Organs ... dermatan sulfate …
Matched Name: … Dermatan sulfate …
Matched Salts name: … Dermatan sulfate sodium …
Matched Categories: … Blood and Blood Forming Organs ... dermatan sulfate …
Posoleucel
Investigational
Matched Synonyms: … specific T lymphocytes targeting BK virus, cytomegalovirus, human herpes virus-6, Epstein Barr virus, and …
Esomeprazole
Esomeprazole, sold under the brand name Nexium, is a proton pump inhibitor (PPI) medication used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison...
Approved
Investigational
Matched Description: … This effect leads to inhibition of both basal and stimulated gastric acid secretion, irrespective of ... infections (including gastrointestinal _C. difficile_), reduced absorption of micronutrients such as iron ... and B12, and an increased risk of developing hypomagnesemia and hypocalcemia which may contribute to …
Matched Mixtures name: … Naproxen and esomeprazole magnesium ... Naproxen and esomeprazole magnesium ... Naproxen and Esomeprazole Magnesium …
Matched Salts name: … Esomeprazole sodium ... Esomeprazole magnesium ... Esomeprazole magnesium dihydrate ... Esomeprazole magnesium trihydrate …
Matched Categories: … Medications that reduce magnesium levels ... Acid Reducers ... Alimentary Tract and Metabolism ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Foster and Thrive Acid Reducer ... Up and Up Esomeprazole Magnesium ... Berkley and Jensen Heartburn Treatment …
Matched Mixtures name: … Naproxen and esomeprazole magnesium ... Naproxen and esomeprazole magnesium ... Naproxen and Esomeprazole Magnesium …
Matched Salts name: … Esomeprazole sodium ... Esomeprazole magnesium ... Esomeprazole magnesium dihydrate ... Esomeprazole magnesium trihydrate …
Matched Categories: … Medications that reduce magnesium levels ... Acid Reducers ... Alimentary Tract and Metabolism ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Foster and Thrive Acid Reducer ... Up and Up Esomeprazole Magnesium ... Berkley and Jensen Heartburn Treatment …
Lidocaine
Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication . In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local...
Approved
Vet approved
Matched Description: … Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an ... , it can block or decrease muscle contractile, resulting in effects like vasodilation, hypotension, and ... It ultimately elicits its numbing activity by blocking sodium channels so that the neurons of local tissues …
Matched Mixtures name: … Hyaluronic Acid 60mg and Lidocaine 2% PF ... Cimetidine 10% / Lidocaine 5% / Salicylic Acid 40% ... Lidocaine Hydrochloride and Epinephrine …
Matched Salts name: … Lidocaine hydrochloride anhydrous ... Lidocaine hydrochloride …
Matched Categories: … Analgesics and Anesthetics ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Antipruritics and Local Anesthetics ... Sodium Channel Blockers ... Voltage-Gated Sodium Channel Blockers …
Matched Products: … Zingo ... Lidocaine Hydrochloride and Dextrose ... Terrasil Rash and Pain Relief …
Matched Mixtures name: … Hyaluronic Acid 60mg and Lidocaine 2% PF ... Cimetidine 10% / Lidocaine 5% / Salicylic Acid 40% ... Lidocaine Hydrochloride and Epinephrine …
Matched Salts name: … Lidocaine hydrochloride anhydrous ... Lidocaine hydrochloride …
Matched Categories: … Analgesics and Anesthetics ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Antipruritics and Local Anesthetics ... Sodium Channel Blockers ... Voltage-Gated Sodium Channel Blockers …
Matched Products: … Zingo ... Lidocaine Hydrochloride and Dextrose ... Terrasil Rash and Pain Relief …
Muparfostat
Muparfostat (PI-88) is a mixture of highly sulfated, monophosphorylated mannose oligosaccharides, derived from the extracellular phosphomannan of the yeast Pichia (Hansenula) holstii, with potential antiangiogenic activity.
Investigational
Matched Synonyms: … Phosphomannopentaose sulfate ... Mannopentaose phosphate sulfate ... Sulfated mannopentaose phosphate …
Matched Iupac: … methyl]oxan-3-yl]oxy}oxan-4-yl]oxy}-6-[(phosphonooxy)methyl]-4,5-bis(sulfooxy)oxan-3-yl)oxidanesulfonic acid …
Matched Description: … Muparfostat (PI-88) is a mixture of highly sulfated, monophosphorylated mannose oligosaccharides, derived …
Matched Salts name: … Muparfostat sodium …
Matched Iupac: … methyl]oxan-3-yl]oxy}oxan-4-yl]oxy}-6-[(phosphonooxy)methyl]-4,5-bis(sulfooxy)oxan-3-yl)oxidanesulfonic acid …
Matched Description: … Muparfostat (PI-88) is a mixture of highly sulfated, monophosphorylated mannose oligosaccharides, derived …
Matched Salts name: … Muparfostat sodium …
Famotidine
Famotidine is a competitive histamine-2 (H2) receptor antagonist that works to inhibit gastric acid secretion. It is commonly used in gastrointestinal conditions related to acid secretion, such as gastric ulcers and gastroesophageal reflux disease (GERD), in adults and children. Compared to other H2 receptor antagonists, famotidine displays high selectivity towards...
Approved
Matched Description: … gastric acid secretion than [cimetidine] and eight times more potent than [ranitidine] on a weight basis ... and gastroesophageal reflux disease (GERD), in adults and children. ... [A189462] Famotidine is used in various over-the-counter and off-label uses. …
Matched Mixtures name: … Healthy Accents Famotidine Calcium Carbonate Magnesium Hydroxide ... Up and Up dual action acid controller complete ... Up and Up Acid Controller Complete Dual Action …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) ... Acid Reducers ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders …
Matched Products: … Up and Up Acid Reducer Original Strength ... Up and Up acid reducer original strength ... Berkley and Jensen Acid Controller …
Matched Mixtures name: … Healthy Accents Famotidine Calcium Carbonate Magnesium Hydroxide ... Up and Up dual action acid controller complete ... Up and Up Acid Controller Complete Dual Action …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) ... Acid Reducers ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders …
Matched Products: … Up and Up Acid Reducer Original Strength ... Up and Up acid reducer original strength ... Berkley and Jensen Acid Controller …
TRK-001
TRK-001 is an autologous regulatory T-cell therapy. It is being investigated for the prevention of graft rejection following solid organ transplantation.
Investigational
Matched Synonyms: … Regulatory T Cells (T-Regs), Expanded with Interleukin-2, ExpAct Beads (CD3/CD28; Miltenyi), Rapamycin and …
Colistin
Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.
Approved
Matched Description: … It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes …
Matched Mixtures name: … COLISTINA SULFATO+HIDROCORTISONA ACETATO+NEOMICINA SULFATO ... COLISTINA SULFATO+HIDROCORTISONA ACETATO+NEOMICINA SULFATO …
Matched Salts name: … Colistin sulfate …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism …
Matched Products: … YH Colistin Sulfate 10% w/w Granule ... Colistin Sulphate 10% w/w Oral Granules. ... Livzon Colistin Sulphate 10% Premix (Granules) …
Matched Mixtures name: … COLISTINA SULFATO+HIDROCORTISONA ACETATO+NEOMICINA SULFATO ... COLISTINA SULFATO+HIDROCORTISONA ACETATO+NEOMICINA SULFATO …
Matched Salts name: … Colistin sulfate …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism …
Matched Products: … YH Colistin Sulfate 10% w/w Granule ... Colistin Sulphate 10% w/w Oral Granules. ... Livzon Colistin Sulphate 10% Premix (Granules) …
Delolimogene mupadenorepvec
Investigational
Matched Synonyms: … Dna (synthetic human adenovirus 5/35 vector load703 human cd137 ligand and trimerized membrane-bound …
Cotsiranib
Investigational
Matched Synonyms: … interfering RNA (siRNA) therapeutic directed against transforming growth factor-beta 1 (TGF-beta 1) and …
PEP0101
PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) designed to down-regulate the expression of EVI1 oncogene in cancer cells.
Investigational
Matched Synonyms: … Nanocomplex consisting of a small interfering RNA that targets the human EV11 oncogenic transcription factor and …
Matched Description: … PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) …
Matched Description: … PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) …
Triptorelin
Triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion. After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. Serum testosterone concentrations may fall to levels...
Approved
Vet approved
Matched Description: … and testicular and ovarian steroidogenesis. ... After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormones and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION 3.75 mg/vial ... POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION 11.25 mg/vial …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormones and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION 3.75 mg/vial ... POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION 11.25 mg/vial …
Witch hazel
Nutraceutical
Matched Mixtures name: … frida mom Labor and Delivery Plus Postpartum Recovery ... frida mom Labor and Delivery Plus Postpartum Recovery ... Tucks Multi-Care Relief Kit (Tucks Hemorrhoidal and Tucks Medicated Cooling 40 Count) …
Matched Categories: … Astringents and Deodorants ... Herbs and Natural Products ... Skin and Mucous Membrane Agents …
Matched Products: … Folli Pilose Revitalizing Follicle ... Up and Up Medicated Hemorrhoidal Pads ... Tone and Line Change Pack …
Matched Categories: … Astringents and Deodorants ... Herbs and Natural Products ... Skin and Mucous Membrane Agents …
Matched Products: … Folli Pilose Revitalizing Follicle ... Up and Up Medicated Hemorrhoidal Pads ... Tone and Line Change Pack …
Zenocutuzumab
Zenocutuzumab is under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and With Endocrine Therapy in ER+ and Low HER2 Breast Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g1, bispecific, anti-(human epidermal growth factor receptors, her2 and her3) (humanized ... antibody with enhanced antibody-dependent cell-mediated cytotoxicity (adcc) activity targeting her2 and …
Matched Description: … With Endocrine Therapy in ER+ and Low HER2 Breast Cancer). ... under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … With Endocrine Therapy in ER+ and Low HER2 Breast Cancer). ... under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Dimethicone
Dimethicone is a silicone oil that is also known as polydimethylsiloxane (PDMS). It has viscoelastic properties. Dimethicone is used as a surfactant, antifoaming agent, carminative in various products such as medical devices, food products, and lubricants. It is used in a number of health and beauty products including hair care...
Approved
Matched Description: … for children and may serve as less toxic and less resistance-prone alternative to pesticide-containing ... , leave-in conditioner, and de-tangling products. ... surfactant, antifoaming agent, carminative in various products such as medical devices, food products, and …
Matched Mixtures name: … DIMETHICONE and ZINC OXIDE ... Zinc Oxide and Dimethicone with Dimethicone ... Alumina, Magnesia, and Simethicone …
Matched Categories: … Basic Ointments and Protectants ... Antiparasitic Products, Insecticides and Repellents ... Skin and Mucous Membrane Agents ... Scabicides, Insecticides and Repellents ... Scabicides and Pediculicides …
Matched Products: … Mi-Acid Gas Relief ... Hyaluronic Acid Collagen Essence Mask ... Super Serum Anti Aging and Firming …
Matched Mixtures name: … DIMETHICONE and ZINC OXIDE ... Zinc Oxide and Dimethicone with Dimethicone ... Alumina, Magnesia, and Simethicone …
Matched Categories: … Basic Ointments and Protectants ... Antiparasitic Products, Insecticides and Repellents ... Skin and Mucous Membrane Agents ... Scabicides, Insecticides and Repellents ... Scabicides and Pediculicides …
Matched Products: … Mi-Acid Gas Relief ... Hyaluronic Acid Collagen Essence Mask ... Super Serum Anti Aging and Firming …
Taniraleucel
Investigational
Matched Synonyms: … Flt3 ligand, IL-7, IL-15 and IL-2 to generate the NK cell ... The cells are expanded and differentiated in the presence of cytokines including thrombopoietin, SCF, …
Pacanalotamab
Investigational
Matched Synonyms: … engager antibody with a single chain fc moiety that binds to b cell maturation antigen surface receptor and …
Cetirizine
Cetirizine, also commonly known as Zyrtec, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and other symptoms , .
One of the most common uses for this drug is for a condition called allergic...
Approved
Matched Iupac: … 2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid …
Matched Description: … in the treatment of various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and ... prevalence of allergic rhinitis in the United States is about 15% according to physician diagnoses, and ... with sleep, and other difficulties with day to day activities for many individuals [A175057]. …
Matched Mixtures name: … Cetirizine Hydrochloride and Pseudoephedrine Hydrochloride ... Cetirizine Hydrochloride and Pseudoephedrine Hydrochloride ... Cetirizine Hydrochloride and Pseudoephedrine Hydrochloride …
Matched Salts name: … Cetirizine hydrochloride …
Matched Categories: … Cetirizine and isomer ... Decongestants and Antiallergics …
Matched Products: … Berkley and Jensen Cetirizine Hydrochloride ... Berkley and Jensen Childrens Cetirizine Hydrochloride ... ZINE …
Matched Description: … in the treatment of various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and ... prevalence of allergic rhinitis in the United States is about 15% according to physician diagnoses, and ... with sleep, and other difficulties with day to day activities for many individuals [A175057]. …
Matched Mixtures name: … Cetirizine Hydrochloride and Pseudoephedrine Hydrochloride ... Cetirizine Hydrochloride and Pseudoephedrine Hydrochloride ... Cetirizine Hydrochloride and Pseudoephedrine Hydrochloride …
Matched Salts name: … Cetirizine hydrochloride …
Matched Categories: … Cetirizine and isomer ... Decongestants and Antiallergics …
Matched Products: … Berkley and Jensen Cetirizine Hydrochloride ... Berkley and Jensen Childrens Cetirizine Hydrochloride ... ZINE …
Docusate
Docusate, or dioctyl sulfosuccinate, is a stool softener indicated for the treatment of constipation . Docusate acts by increasing the amount of water the stool absorbs in the gut, making the stool softer and easier to pass . Docusate can be orally or rectally administered. Docusate is on the World...
Approved
Matched Iupac: … 1,4-bis[(2-ethylhexyl)oxy]-1,4-dioxobutane-2-sulfonic acid …
Matched Description: … Docusate acts by increasing the amount of water the stool absorbs in the gut, making the stool softer and …
Matched Mixtures name: … Prenatal Vitamin No 53 Iron Fum Folic Acid Docusate CA DHA ... PNV Ferrous Fumarate Docusate Folic Acid ... Iron …
Matched Salts name: … Docusate calcium ... Docusate sodium …
Matched Categories: … Alimentary Tract and Metabolism ... Softener and Emollient Laxatives …
Matched Products: … Up and up stool softener ... Stool Softener easy and gentle ... Docusate Calcium 240 mg sodium free …
Matched Description: … Docusate acts by increasing the amount of water the stool absorbs in the gut, making the stool softer and …
Matched Mixtures name: … Prenatal Vitamin No 53 Iron Fum Folic Acid Docusate CA DHA ... PNV Ferrous Fumarate Docusate Folic Acid ... Iron …
Matched Salts name: … Docusate calcium ... Docusate sodium …
Matched Categories: … Alimentary Tract and Metabolism ... Softener and Emollient Laxatives …
Matched Products: … Up and up stool softener ... Stool Softener easy and gentle ... Docusate Calcium 240 mg sodium free …
Displaying drugs 226 - 250 of 3048 in total