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Displaying drugs 226 - 250 of 722 in total
Cabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree. As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and induces tumour cell death. Due to its low affinity for the P-glycoprotein (P-gp) efflux pump, cabazitaxel can more readily penetrate the blood–brain barrier compared to...
Approved
Matched Synonyms: … -DIMETHOXY-9-OXO-5.BETA.,20-EPOXYTAX-11-ENE-2.ALPHA.,4,13.ALPHA. …
Matched Iupac: … 10S,12R,15S)-4-(acetyloxy)-15-{[(2R,3S)-3-{[(tert-butoxy)carbonyl]amino}-2-hydroxy-3-phenylpropanoyl]oxy ... }-1-hydroxy-9,12-dimethoxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^{3,10}.0^{4,7}]heptadec …
Matched Description: … [A260421] It was also approved by the EMA on March 17, 2011 [L47381] and Health Canada on December 17 ... It was first approved by the FDA on June 17, 2010. ... A260621] As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … JEVTANA 60mg CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION ... JEVTANA (CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION) ... Concentrate and Solvent for Solution for Infusion 60mg/1.5ml …
Aluminum zirconium pentachlorohydrate is a common active ingredient in personal care products as an antiperspirant agent. Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing sweat from leaving the body.
Approved
Matched Description: … Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing …
Matched Products: … On Duty 24 Hours Clear Protection Roll-On Anti-Perspirant Deodorant ... Skin So Soft Soft and Sensual Anti-Perspirant Deodorant ... Skin So Soft Fresh and Smooth Moisturizing Hair Minimizing Anti-Perspirant Deodorant …
Colloidal oatmeal is produced by grinding fine granules of oatmeal and boiling it to extract the colloidal material. It contains high concentrations of starches and beta-glucan that exhibits water-absorbing properties. Phenols are also contained in colloidal oatmeal, which possess antioxidant and anti-inflammatory activities, as well as UV-absorbing activity. Colloidal oatmeal...
Approved
Nutraceutical
Matched Synonyms: … Oat flour ... Oat Kernel Meal ... Oat Grain Hulled …
Matched Description: … skin irritation and itching due to rashes, eczema, poison ivy, oak, sumac, or insect bites. ... Colloidal oatmeal is produced by grinding fine granules of oatmeal and boiling it to extract the colloidal ... It contains high concentrations of starches and beta-glucan that exhibits water-absorbing properties. …
Matched Mixtures name: … Dermavive Shower and Bath Oil ... 5% Oat Facial Cleanser ... Infinite Aloe All-IN-one Skin Care …
Matched Products: … JOSIE MARAN OTC ECZEMA BODY BUTTER -Vanilla and Chamomile ... Little Twig 8.5 OZ Oat Babywash ... OMV Anti-Itch Bikini …
Guaifenesin possesses a storied history, having been originally formally approved by the US FDA in 1952 and continues to be one of very few - if not perhaps the only drug that is readily available and used as an expectorant . Since that time the agent has been a combination...
Approved
Investigational
Vet approved
Matched Description: … continues to be one of very few - if not perhaps the only drug that is readily available and used as ... to be safe and effective in children under the age of 6 years [F4525]. ... Since that time the agent has been a combination component of various prescription and non-prescription …
Matched Mixtures name: … ANDIS OBP ANAK ... Cold and Flu All In One ... DEF OBH
Matched Categories: … Cough and Cold Preparations …
Matched Products: … Cough Out ... RE-TUSIN OFF SOLUCION ORAL ... Up and Up Mucus Relief …
Investigational
Matched Synonyms: … homopolymer, complex with 5'-inosinic acid homopolymer (1:1), compd. with cellulose carboxymethyl ether and ... L-lysine, homopolymer, compd. with cellulose carboxymethyl ether and 5'-inosinic acid homopolymer complex ... homopolymer, complex with 5'-cytidylic acid homopolymer (1:1), compd. with cellulose carboxymethyl ether and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
The human von Willebrand factor (vWF) is a human plasma-derived vWF, an endogenous large multimeric plasma glycoprotein involved in hemostasis. It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood vessel injury and stabilizing procoagulant factor VIII (FVIII). Exogenous sources of vWF...
Approved
Investigational
Matched Description: … It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood ... [L1878] A recombinant form of vWF, [vonicog alfa], is also available to enhance production and avoid ... and hemophilia A. …
Matched Mixtures name: … Haemate P Powder and solvent for solution for injection or infusion ... Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for Injection ... Wilate 1000, 1000 IU VWF/1000 IU FVIII, Powder and Solvent for Solution for Injection …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... von Willebrand factor and coagulation factor VIII in combination …
Matched Products: … IMMUNATE 50 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... IMMUNATE 100 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Investigational
Matched Synonyms: … 3-o-(2-acetamido-2-deoxy-.alpha.-d-galactopyranosyl)-2-o-(.alpha.-l-fucopyranosyl)-d-galactose …
Matched Iupac: … 3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}hexan-3-yl]oxy}oxan-3-yl]acetamide ... N-[(2R,3R,4R,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-{[(2R,3S,4S,5R)-4,5,6-trihydroxy-1-oxo-2-{[(2S, …
TRK-001 is an autologous regulatory T-cell therapy. It is being investigated for the prevention of graft rejection following solid organ transplantation.
Investigational
Matched Synonyms: … Regulatory T Cells (T-Regs), Expanded with Interleukin-2, ExpAct Beads (CD3/CD28; Miltenyi), Rapamycin and
Matched Description: … It is being investigated for the prevention of graft rejection following solid organ transplantation. …
Investigational
Matched Synonyms: … D-streptamine, o-5-amino-5,6-dideoxy-.beta. ... -d-allofuranosyl-(1->5)-o-(2-amino-2,7-dideoxy-d-glycero-.alpha. ... 6'-(r)-methyl-5-o-(5-amino-5,6-dideoxy-a-l-talofuranosyl)- paromamine sulfate …
Matched Iupac: … }-3-hydroxycyclohexyl]oxy}-2-[(1R)-1-hydroxyethyl]oxane-3,4-diol; sulfuric acid ... amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-5-[(1S)-1-aminoethyl]-3,4-dihydroxyoxolan-2-yl]oxy
Carbidopa presents a chemical denomination of N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate. It potently inhibits aromatic amino acid decarboxylase (DDC) and due to its chemical properties, it does not cross the blood-brain barrier. Due to its activity, carbidopa is always administered concomitantly with levodopa. An individual formulation containing solely carbidopa was generated to treat...
Approved
Matched Description: … approved on 2014. ... It potently inhibits aromatic amino acid decarboxylase (DDC) and due to its chemical properties, it does ... approved product by the FDA containing only carbidopa was developed by Amerigens Pharmaceuticals Ltd and
Matched Mixtures name: … LEVOCAENT OR 100/25/200 ... LEVOCAENT OR 100/25/200 ... LEVOCAENT OR 100/25/200 …
Matched Products: … Carbidopa and Levodopa ... Carbidopa and levodopa …
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
Approved
Matched Description: … Nicotine is also important medically because of its presence in tobacco smoke. ... the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and
Matched Mixtures name: … Nicorette and Aquafresh Fruit Chill and Extreme Clean Whitening …
Matched Products: … Care One Nicotine ... Up and Up Nicotine ... Up and Up nicotine …
Investigational
Matched Synonyms: … The cells are expanded and differentiated in the presence of cytokines including thrombopoietin, SCF, ... Flt3 ligand, IL-7, IL-15 and IL-2 to generate the NK cell …
Zenocutuzumab is under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and With Endocrine Therapy in ER+ and Low HER2 Breast Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g1, bispecific, anti-(human epidermal growth factor receptors, her2 and her3) (humanized ... antibody with enhanced antibody-dependent cell-mediated cytotoxicity (adcc) activity targeting her2 and
Matched Description: … With Endocrine Therapy in ER+ and Low HER2 Breast Cancer). ... under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … 2'-O-phosphoguanosine …
Matched Iupac: … {[(2R,3R,4R,5R)-2-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxy
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Experimental
Matched Synonyms: … 2,3-Di-O-phytanyl-sn-glycerol …
Matched Name: … 2,3-di-O-phytanyl-sn-glycerol …
Matched Iupac: … (2R)-2,3-bis({[(3R,7R,11R)-3,7,11,15-tetramethylhexadecyl]oxy})propan-1-ol
Experimental
Matched Synonyms: … 5-O-phosphono-β-D-arabinofuranose …
Approved
Vet approved
Matched Synonyms: … 21-O-acetylcortisol …
Matched Iupac: … 2-[(1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H …
Matched Mixtures name: … Proctosone Ont ... Ophthocort Ont ... Sopamycetin/hc Ont
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … American Safety and First Aid ... Rectocort Ont ... Cortamed Ont 25 mg/g …
Corn starch refers to the starch extracted from the corn grain that is commonly used as a food ingredient and chemical additive. Starch is any of a group of polysaccharides of the general formula (C6-H10-O5)n, composed of a long-chain polymer of glucose in the form of amylose and amylopectin. Starch...
Approved
Nutraceutical
Matched Description: … polymer of glucose in the form of amylose and amylopectin. ... Corn starch may be added in some food products as a thickening agent or anti-caking agent, and is sometimes ... starch refers to the starch extracted from the corn grain that is commonly used as a food ingredient and
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Soothe and Cool Non-Caking Body ... Lotrimin Daily Sweat and Odor Control …
Investigational
Matched Synonyms: … Dna (synthetic human adenovirus 5/35 vector load703 human cd137 ligand and trimerized membrane-bound …
Investigational
Matched Synonyms: … interfering RNA (siRNA) therapeutic directed against transforming growth factor-beta 1 (TGF-beta 1) and
PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) designed to down-regulate the expression of EVI1 oncogene in cancer cells.
Investigational
Matched Synonyms: … factor and an elastin-like polypeptide drug carrier. ... Nanocomplex consisting of a small interfering RNA that targets the human EV11 oncogenic transcription …
Matched Description: … PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) ... designed to down-regulate the expression of EVI1 oncogene in cancer cells. …
Undecylenate, or undecylenic acid, is an unsaturated fatty acid with a terminal double bond that is derived from castor oil. Undecylenic acid is also found naturally in the human sweat. It is used as a precursor in the manufacture of aromatic chemicals, polymers or modified silicones . Undecylenic acid was...
Approved
Investigational
Matched Description: … of ricinoleic acid, and has been polymerized for vinyl production [A32281]. ... ’s foot and relieves itching, burning, and irritation associated with the skin condition. ... from castor oil. …
Matched Mixtures name: … Desenex Medicated Spray-ON Powder ... Desenex Medicated Spray-ON Powder ... Foot and Body Powder …
Matched Products: … Pinceladas Goyescas Original Brush on Fungicide ... Fungi Nail Toe and Foot ... Fungi Nail Toe and Foot Pen …
Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt, sodium salt. Indocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. Each vial of Indocyanine Green for...
Approved
Investigational
Matched Description: … Each vial of Indocyanine Green for Injection USP contains 25 mg of Indocyanine Green as a sterile lyophilized ... Indocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Spy Agent Green Kit for Advanced Imaging Modality (aim) and Pinpoint ... Spy Agent Green Lymphatics Kit for Advanced Imaging Modality (aim) and Pinpoint …
Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil, and induce local vasoconstriction. The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s. Phenylephrine was granted FDA approval in 1939.
Approved
Matched Description: … [A187370] The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s ... alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil,[L9413] and
Matched Mixtures name: … Mineral Oil, Petrolatum and Phenylephrine HCl ... Mineral Oil, Petrolatum, Phenylephrine Hydrochloride, Shark Liver Oil ... Glycerin, Lidocaine, Petrolatum, and Phenylephrine Hydrochloride …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Compounds used in a research, industrial, or household setting ... Mydriatics and Cycloplegics ... phenylephrine and ketorolac ... Adrenergic and Dopaminergic Agents …
Matched Products: … OQ-DILAT® ... Care One Nasal Four ... Care One Nose Drops …
Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and/or long-acting bronchodilator. It is available as a tablet and is usually dosed twice daily. Another leukotriene receptor antagonist is montelukast (Singulair), which is usually taken just once...
Approved
Investigational
Matched Synonyms: … cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carbamoyl)benzyl)-1-methylindole-5-carbamate ... 4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol-3-ylmethyl)-3-methoxy-N-o-tolylsulfonylbenzamide …
Matched Description: … of the airways, build-up of mucus in the lungs and inflammation of the breathing passages. ... , often used in conjunction with an inhaled steroid and/or long-acting bronchodilator. ... It is available as a tablet and is usually dosed twice daily. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Displaying drugs 226 - 250 of 722 in total