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Displaying drugs 226 - 250 of 1082 in total

OTL-102

OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human gp91phox gene. It is being investigated for the treatment of X-linked chronic granulomatous disease.
Investigational
Matched Synonyms: … Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced …
Matched Description: … OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells …

Haemophilus influenzae type B strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen

Haemophilus influenzae type b strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen is an active immunization as a booster dose given intramuscularly to pediatric patients who have received a primary series with a Haemophilus b Conjugate Vaccine that is licensed for primarly immunization. The vaccine contains Haemophilus b capsular polysaccharide...
Approved
Investigational
Matched Synonyms: … Haemophilus influenzae type B-PRP and tetanus toxoid conjugate (PRP-T) …
Matched Description: … These are heat inactivated and purified. …

Apadamtase alfa

Thrombotic thrombocytopenic purpura (TTP) is a rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and various degrees of organ damage. It may be inherited (congenital TTP; cTTP) or acquired due to autoantibodies (immune-mediated TTP; iTTP), although cTTP accounts for <5% of all cases of TTP. Patients with cTTP...
Approved
Investigational
Matched Synonyms: … Recombinant disintegrin and metalloprotease with thrombospondin type 1 motifs …
Matched Description: … rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and ... Patients with cTTP have a severe deficiency of a plasma metalloproteinase called ADAMTS13 (a disintegrin and ... thrombospondin type 1 motif, member 13), which is responsible for cleaving large von Willebrand factor multimers and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes ... apadamtase alfa and cinaxadamtase alfa ... ADAM Proteins …

Glycerin

A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.
Approved
Investigational
Matched Description: … A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism. …
Matched Mixtures name: … Hand and Nature Anti Wrinkle Hand Aragon Oil ... Hand and Nature Anti Wrinkle Hand Almond Oil ... Nature and Health Beauty (Moisturizing Cream, Whitening Cream) (Mineral Oil and Glycerin) …
Matched Categories: … Alimentary Tract and Metabolism ... Basic Ointments and Protectants ... Other Cold and Cough Preparations …
Matched Products: … MEDICLEAR DUAL SPOT DAY and NIGHT ... Bee Venom Treatment Spot ... Eros Tasty Fruits …

Naproxen

Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994. It can effectively manage acute pain as well as pain related to rheumatic diseases, and has a well studied adverse effect profile. Given its...
Approved
Vet approved
Matched Description: … Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for ... prescription use in 1976 and then for over-the-counter (OTC) use in 1994. ... [A178975] It can effectively manage acute pain as well as pain related to rheumatic diseases, and has …
Matched Mixtures name: … MOVIDOL PROTEC ... Good Sense Naproxen Sodium ... Sudafed Sinus and Pain 12 Hour …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Genito Urinary System and Sex Hormones ... naproxen and misoprostol ... sumatriptan and naproxen …
Matched Products: … Naprosyn Sus 25mg/ml ... Good Sense All Day Pain Relief ... Up and Up Naproxen sodium …

Nicotinamide

An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
Approved
Investigational
Matched Description: … Its primary significance is in the prevention and/or cure of blacktongue and pellagra. ... Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and …
Matched Mixtures name: … Therapytion Nokmosu Neutral and oily Hair ... Ra Sence Loe Cure Solu tion Aloe Mask ... CH6 Ginger Beer Anti Hair Loss Scalp …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Barox White Golf ... Dr.g Lock and More A-clear Mask ... P8 Tone - Up and Brightening CreamEX …

Butylidenephthalide

Investigational
Matched Synonyms: … 3-butylidenephthalide, mixture of cis and trans isomers …

OTL-203

OTL-203 is an autologous CD34+ enriched cell therapy that contains hematopoietic stem and progenitor cells transduced ex-vivo using a lentiviral vector encoding alpha-L-iduronidase gene.
Investigational
Matched Synonyms: … Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced …
Matched Description: … OTL-203 is an autologous CD34+ enriched cell therapy that contains hematopoietic stem and progenitor …

Methylcellulose

Methyl cellulose polymer consisting of numerous linked glucose molecules used as a stabiliser, thickener and emulsifier for foodstuffs and cosmetics. The Degree of Substitution (DS) of a given form of methyl cellulose is defined as the average number of substituted hydroxyl groups per glucose with a theoretical maximum of 3,...
Approved
Matched Description: … emulsifier for foodstuffs and cosmetics. ... Methyl cellulose polymer consisting of numerous linked glucose molecules used as a stabiliser, thickener and ... Like cellulose, it is not digestible, not toxic, and not allergenic …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Foster and Thrive Fiber Laxative 188 …

Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine

Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine is used to prevent invasive meningococcal disease, which is caused by bacteria Neisseria meningitidis entering the bloodstream and invading the blood-brain barrier to cause a variety of infections such as septicemia, meningitis, and pneumonia. Several serogroups of N....
Approved
Matched Name: … Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine …
Matched Description: … infections have been identified. ... _ CRM197 protein carrier, resulting in four drug substances contained in each dose of vaccine. ... Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine is used …

Tavokinogene telseplasmid

Tavokinogene telseplasmid consists of a DNA Plasmid Vector Encoding IL-12.
Investigational
Matched Synonyms: … Dna plasmid containing genes coding for the human interleukin 12 (il-12) p35 and p40 subunits that are ... separated by an internal ribosomal entry site (ires) and under the control of a single cytomegalovirus …

Azercabtagene zapreleucel

Investigational
Matched Synonyms: … Adult allogeneic CD4+ and CD8+ enriched T cells transduced with an anti-CD19 chimeric antigen receptor ... Adult allogeneic CD4+ and CD8+ enriched T cells, gene edited through the electroporati …

Ergidina

Ergidina is a recombinant human minibody against complement component C5 fused with RGD-motif.
Investigational
Matched Synonyms: … Neutralizing scFv dimer to C5 fused at the C terminal end to the Fc domains of human IgG1 and the cyclic …

Oxymetazoline

Oxymetazoline is an imidazole derivative and a potent, direct-acting alpha (α)-adrenergic agonist with affinity to both α1- and α2-adrenoceptors. Oxymetazoline is available in various formulations with a wide variety of clinical implications. The topical formulation of the drug is used to treat persistent facial redness in adults. As an effective...
Approved
Investigational
Matched Description: … Oxymetazoline is an imidazole derivative and a potent, direct-acting alpha (α)-adrenergic agonist with ... affinity to both α1- and α2-adrenoceptors. ... is used for regional anesthesia during dental procedures in children and adults. …
Matched Mixtures name: … Mucinex Sinus-Max Pressure, Pain and Cough and Mucinex Sinus-Max Severe Congestion Relief Clear and Cool …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Breaze Nasal Sinus Colds and Allergies ... Up and Up Nasal Extra Moisturizing ... Up and Up nasal …

Diphenhydramine

Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation H1 receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and stings, and rashes [L5263, L5266, L5269, F3379]. However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269,...
Approved
Investigational
Matched Description: … stings, and rashes [L5263, L5266, L5269, F3379]. ... Diphenhydramine is also used in combination with [DB14132] as the anti-nausea drug [DB00985] where it ... repurposed for use within many non-prescription over-the-counter sleep aids and cough-and-cold medications …
Matched Mixtures name: … Live Better Anti-Itch ... Good Sense Flu and Severe Cold and Cough ... Smart Sense Childrens Nighttime Cold and Cough …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Hypnotics and Sedatives ... naproxen and diphenhydramine …
Matched Products: … Benatu Sleep Essential Oil ... Up and Up Nighttime Sleep-aid ... Up and Up Allergy Relief …

Quinoline Yellow WS

Experimental
Matched Synonyms: … D and C Yellow No. 10 …

Loratadine

Loratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis. A lack of sedative and CNS adverse effects make loratadine, along with other second generation antihistamines, preferable over their 1st generation counterparts in many clinical situations.
Approved
Investigational
Matched Description: … [A176435] A lack of sedative and CNS adverse effects make loratadine, along with other second generation …
Matched Mixtures name: … Good Sense Allergy and Congestion Relief ... Smart Sense Allergy and Congestion Relief ... Smart Sense Allergy and Congestion Relief …
Matched Categories: … Loratadine and derivatives …
Matched Products: … Live Better Loratadine ... Up and Up Allergy Relief ... Up and Up Childrens Allergy Relief …

Isopropyl alcohol

An isomer of 1-propanol. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.
Approved
Investigational
Matched Description: … It is used in the manufacture of acetone and its derivatives and as a solvent. …
Matched Mixtures name: … Pro - Sponge ... 3m Soluprep Sponge ... CVS Health Sports Kit …
Matched Categories: … Antiseptics and Disinfectants …
Matched Products: … AZ Clean and Soft Professional Leave-on Hand Sanitizer ... Roots Aromatherapy ... B-Protek …

Leuprolide

Leuprolide is a synthetic 9-residue peptide analogue of gonadotropin-releasing hormone (GnRH). Unlike the endogenous decapeptide GnRH, leuprolide contains a single D-amino acid (D-leucyl) residue, which helps to increase its circulating half-life from three to four minutes to approximately three hours. As a GnRH mimic, leuprolide is capable of binding to...
Approved
Investigational
Matched Description: … downstream modulation of both gonadotropin hormone and sex steroid levels. ... [A203222] As a GnRH mimic, leuprolide is capable of binding to the GnRH receptor (GnRHR) and inducing ... clinical efficacy of leuprolide in diverse conditions, including advanced prostate cancer, endometriosis, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Adrenal Cortex Hormones ... Antineoplastic and Immunomodulating Agents ... Hormones and Related Agents ... leuprorelin and bicalutamide …
Matched Products: … POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 45mg ... POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 22.5mg ... POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 7.5mg …

Glyceryl monostearate

Glycerol monostearate, commonly known as GMS, is the glycerol ester of stearic acid . It is commonly used as an emulsifier in foods.
Experimental
Matched Synonyms: … Geleol mono and diglycerides …

Benzethonium

Benzethonium is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties. Its salt form, benzethonium chloride, is primarily used as a skin disinfectant at concentrations of 0.1-0.2 %, which are safe and effective concentrations for the compound specified by the U.S. Food and Drug Administration (FDA)....
Approved
Matched Description: … Benzethonium is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum ... Food and Drug Administration (FDA). ... It is additionally found in cosmetics and toiletries such as mouthwashes and anti-itch ointments. …
Matched Mixtures name: … Aspiera Wound Care and Antiseptic ... Aspiera Wound Care and Antiseptic ... Benzocaine and Benzethonium …
Matched Categories: … Antiseptics and Disinfectants …
Matched Products: … LYSOL Healthy Touch Cleansing Green Tea and Ginger ... LYSOL Healthy Touch Aloe Vera And Vitamin E with Moisturizers ... Foaming Instant Hand Sanitizer with Aloe and Vitamin E …

Propylene glycol

A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
Approved
Investigational
Matched Description: … A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations. …
Matched Mixtures name: … Systane Sport ... Systane Day and Night Value Pack ... Systane Day and Night Value Pack …
Matched Products: … Eyelash and Eyebrow Lengthener …

Gibberella fujikuroi

Gibberella fujikuroi allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, fusarium moniliforme …

AD-214

Investigational
Matched Synonyms: … and 3 of the Fc region of a mutated human IgG1 ... Fc-fusion protein comprised of an anti-CXCR4 i-body tethered at its C-terminus to constant domains 2 …

Cetirizine

Cetirizine, also commonly known as Zyrtec, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and other symptoms , . One of the most common uses for this drug is for a condition called allergic...
Approved
Matched Description: … in the treatment of various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and ... prevalence of allergic rhinitis in the United States is about 15% according to physician diagnoses, and ... with sleep, and other difficulties with day to day activities for many individuals [A175057]. …
Matched Mixtures name: … Good Sense All Day Allergy D ... Smart Sense Allergy Relief D ... Good Sense All Day Allergy D …
Matched Categories: … Cetirizine and isomer ... Decongestants and Antiallergics …
Matched Products: … Up and Up Allergy Relief ... Up and Up Childrens All Day Allergy Relief ... Up and Up All Day Allergy Relief …
Displaying drugs 226 - 250 of 1082 in total