Displaying drugs 2501 - 2525 of 3128 in total
Reserpine
An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool,...
Approved
Investigational
Withdrawn
Matched Synonyms: … 16beta,17alpha,18beta,20alpha)-11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid …
Matched Description: … An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. ... serotonin from central and peripheral axon terminals. ... inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and …
Matched Categories: … reserpine and diuretics ... reserpine and diuretics, combinations with other drugs ... reserpine and diuretics, combinations with psycholeptics …
Matched Description: … An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. ... serotonin from central and peripheral axon terminals. ... inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and …
Matched Categories: … reserpine and diuretics ... reserpine and diuretics, combinations with other drugs ... reserpine and diuretics, combinations with psycholeptics …
VPO-227
Investigational
Matched Synonyms: … phenyl-8-oxa-1,12,14-triazatetracyclo[8.7.0.02,7.011,16]heptadeca-2(7),3,5,10,16-pentaene-4-carboxylic acid …
Matched Iupac: … -8-oxa-1,12,14-triazatetracyclo[8.7.0.0^{2,7}.0^{11,16}]heptadeca-2,4,6,10,16-pentaene-4-carboxylic acid …
Matched Iupac: … -8-oxa-1,12,14-triazatetracyclo[8.7.0.0^{2,7}.0^{11,16}]heptadeca-2,4,6,10,16-pentaene-4-carboxylic acid …
Carbenicillin
Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function.
Approved
Investigational
Matched Synonyms: … N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)hept-6-yl)-2-phenylmalonamic acid ... -6-{[carboxy(phenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … )-6-(2-carboxy-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … It is susceptible to gastric juice and penicillinase and may damage platelet function. …
Matched Iupac: … )-6-(2-carboxy-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … It is susceptible to gastric juice and penicillinase and may damage platelet function. …
Pirmitegravir
Pirmitegravir is under investigation in clinical trial NCT05869643 (A Clinical Trial of STP0404 in Treatment-naïve Adults With HIV-1 Infection).
Investigational
Matched Synonyms: … 1H-Pyrrolo[2,3-b]pyridine-5-acetic acid, 4-(4-chlorophenyl)-α-(1,1-dimethylethoxy)-2,3,6-trimethyl-1- ... dimethylethoxy)-2,3,6-trimethyl-1-[(1-methyl-1H-pyrazol-4-yl)methyl]-1H-pyrrolo[2,3-b]pyridine-5-acetic acid …
Oxacillin
An antibiotic similar to flucloxacillin used in resistant staphylococci infections.
Approved
Investigational
Matched Synonyms: … 6β-(5-methyl-3-phenylisoxazol-4-yl)penicillanic acid ... 5-methyl-3-phenylisoxazol-4-yl)carbonyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … dimethyl-6-(5-methyl-3-phenyl-1,2-oxazole-4-amido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Salts name: … Oxacillin sodium ... Oxacillin sodium monohydrate …
Matched Iupac: … dimethyl-6-(5-methyl-3-phenyl-1,2-oxazole-4-amido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Salts name: … Oxacillin sodium ... Oxacillin sodium monohydrate …
Pixofisiran
Investigational
Matched Synonyms: … Cotsiranib tgf-.beta.1 si-rna free acid component ... Stp-705 component tgf-.beta.1 si-rna free acid ... Tgf-.beta.1 si-rna free acid component of cotsiranib …
Matched Salts name: … Pixofisiran sodium …
Matched Salts name: … Pixofisiran sodium …
1-Methylhistidine
Experimental
Matched Synonyms: … (2S)-2-amino-3-(1-methyl-1H-imidazol-4-yl)propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(1-methyl-1H-imidazol-4-yl)propanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic …
Matched Iupac: … (2S)-2-amino-3-(1-methyl-1H-imidazol-4-yl)propanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic …
N-methylnicotinamide
N-methylnicotinamide is an experimental drug with no approved indication or marketed formulation. It is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide is used to diagnose niacin deficiency by measuring N-methylnicotinamide in the urine.
Experimental
Matched Synonyms: … Nicotinic acid methylamide …
Matched Description: … It is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide …
Matched Categories: … Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Acids, Heterocyclic ... Nicotinic Acids …
Matched Description: … It is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide …
Matched Categories: … Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Acids, Heterocyclic ... Nicotinic Acids …
Mavodelpar
Investigational
Matched Synonyms: … REN-001 free acid …
Matched Iupac: … fluorophenyl)-3-{4-[3-(morpholin-4-yl)prop-1-yn-1-yl]phenyl}prop-2-en-1-yl]oxy}-2-methylphenoxy)acetic acid …
Matched Salts name: … Mavodelpar sodium …
Matched Iupac: … fluorophenyl)-3-{4-[3-(morpholin-4-yl)prop-1-yn-1-yl]phenyl}prop-2-en-1-yl]oxy}-2-methylphenoxy)acetic acid …
Matched Salts name: … Mavodelpar sodium …
Levofloxacin
Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic ofloxacin. It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin and remains stereochemically stable following administration (i.e. it does not invert to the inactive isomer). Levofloxacin, along with other quinolones...
Approved
Investigational
Matched Synonyms: … methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid ... dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid ... methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzooxazine-6-carboxylic acid …
Matched Iupac: … methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13),6,8,11-tetraene-11-carboxylic acid …
Matched Description: … several South American countries soon after. ... Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic [ofloxacin]. ... [A31453,A190756] Levofloxacin was first approved by the FDA in 1996, and was approved in Canada and …
Matched Categories: … Alimentary Tract and Metabolism ... levofloxacin and ornidazole ... Metabolic Side Effects of Drugs and Substances ... lansoprazole, amoxicillin and levofloxacin …
Matched Iupac: … methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13),6,8,11-tetraene-11-carboxylic acid …
Matched Description: … several South American countries soon after. ... Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic [ofloxacin]. ... [A31453,A190756] Levofloxacin was first approved by the FDA in 1996, and was approved in Canada and …
Matched Categories: … Alimentary Tract and Metabolism ... levofloxacin and ornidazole ... Metabolic Side Effects of Drugs and Substances ... lansoprazole, amoxicillin and levofloxacin …
Chloroprocaine
Chloroprocaine is an ester local anesthetic commonly available in its salt form, chloroprocaine hydrochloride. Similar to other local anesthetics, it increases the threshold for electrical excitation in nerves by slowing the propagation of the nerve impulse and reducing the rate of rise of the action potential. The pharmacological profile of...
Approved
Investigational
Matched Synonyms: … 4-amino-2-chlorobenzoic acid 2-(diethylamino)ethyl ester …
Matched Description: … [A252952] Chloroprocaine can be given as an injection, and is available in formulations with and without ... formulation can be used for lumbar and caudal epidural blocks. ... increases the threshold for electrical excitation in nerves by slowing the propagation of the nerve impulse and …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Esters of Aminobenzoic Acid …
Matched Description: … [A252952] Chloroprocaine can be given as an injection, and is available in formulations with and without ... formulation can be used for lumbar and caudal epidural blocks. ... increases the threshold for electrical excitation in nerves by slowing the propagation of the nerve impulse and …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Esters of Aminobenzoic Acid …
RU85053
Experimental
Matched Synonyms: … Acetamido-3-oxo-3-[[(3S)-2-oxo-1-[(4-phenylphenyl)methyl]azepan-3-yl]amino]propyl]-2-(carboxymethyl)benzoic acid …
Matched Iupac: … [1,1'-biphenyl]-4-yl}methyl)-2-oxoazepan-3-yl]carbamoyl}-2-acetamidoethyl]-2-(carboxymethyl)benzoic acid …
Matched Iupac: … [1,1'-biphenyl]-4-yl}methyl)-2-oxoazepan-3-yl]carbamoyl}-2-acetamidoethyl]-2-(carboxymethyl)benzoic acid …
Acrivastine
Acrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever. As an H1 receptor antagonist, it functions by blocking the action of histamine at this receptor thereby preventing the symptoms associated with histamine release such as pruritis, vasodilation, hypotension, edema, bronchoconstriction, and tachycardia.
Acrivastine is...
Approved
Matched Synonyms: … (2E)-3-{6-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridin-2-yl}acrylic acid …
Matched Iupac: … (2E)-3-{6-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridin-2-yl}prop-2-enoic acid …
Matched Description: … Acrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever ... associated with histamine release such as pruritis, vasodilation, hypotension, edema, bronchoconstriction, and …
Matched Iupac: … (2E)-3-{6-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridin-2-yl}prop-2-enoic acid …
Matched Description: … Acrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever ... associated with histamine release such as pruritis, vasodilation, hypotension, edema, bronchoconstriction, and …
Cianidanol
An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms.
Approved
Withdrawn
Matched Synonyms: … Catechuic acid …
Matched Description: … An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin …
Matched Description: … An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin …
NP-51
Investigational
Matched Synonyms: … (+/-)-o-(3-piperidino-2-hydroxy-1-propyl)nicotinic acid amidoxime …
Vipoglanstat
Investigational
Matched Synonyms: … dimethyl-propionylamino)-methyl]-phenylamino}-6-(2,2-difluoroethoxy)-1-methyl-1H-benzoimidazole-5-carboxylic acid …
N-2-Thiophen-2-Yl-Acetamide Boronic Acid
Experimental
Matched Name: … N-2-Thiophen-2-Yl-Acetamide Boronic Acid …
Matched Iupac: … {[2-(thiophen-2-yl)acetamido]methyl}boronic acid …
Matched Iupac: … {[2-(thiophen-2-yl)acetamido]methyl}boronic acid …
Vitamin B6 Complexed with 2-Amino-Hexanoic Acid
Experimental
Matched Name: … Vitamin B6 Complexed with 2-Amino-Hexanoic Acid …
Matched Iupac: … (2S)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]hexanoic acid …
Matched Iupac: … (2S)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]hexanoic acid …
Vitamin B6 Complexed with 2-Amino-Pentanoic Acid
Experimental
Matched Name: … Vitamin B6 Complexed with 2-Amino-Pentanoic Acid …
Matched Iupac: … (2S)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]pentanoic acid …
Matched Iupac: … (2S)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]pentanoic acid …
2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid
Experimental
Matched Name: … 2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid …
Matched Iupac: … (2R)-2-[(N-hydroxyformamido)methyl]-4-methylpentanoic acid …
Matched Iupac: … (2R)-2-[(N-hydroxyformamido)methyl]-4-methylpentanoic acid …
2-HYDROXY-5-(2-MERCAPTO-ETHYLSULFAMOYL)-BENZOIC ACID
Experimental
Matched Name: … 2-HYDROXY-5-(2-MERCAPTO-ETHYLSULFAMOYL)-BENZOIC ACID …
Matched Iupac: … 2-hydroxy-5-[(2-sulfanylethyl)sulfamoyl]benzoic acid …
Matched Iupac: … 2-hydroxy-5-[(2-sulfanylethyl)sulfamoyl]benzoic acid …
(2S)-2-HYDROXY-2H-CHROMENE-2-CARBOXYLIC ACID
Experimental
Matched Name: … (2S)-2-HYDROXY-2H-CHROMENE-2-CARBOXYLIC ACID …
Matched Iupac: … (2S)-2-hydroxy-2H-chromene-2-carboxylic acid …
Matched Iupac: … (2S)-2-hydroxy-2H-chromene-2-carboxylic acid …
5-(dodecylthio)-1H-1,2,3-triazole-4-carboxylic acid
Experimental
Matched Name: … 5-(dodecylthio)-1H-1,2,3-triazole-4-carboxylic acid …
Matched Iupac: … 5-(dodecylsulfanyl)-1H-1,2,3-triazole-4-carboxylic acid …
Matched Iupac: … 5-(dodecylsulfanyl)-1H-1,2,3-triazole-4-carboxylic acid …
(2R)-3-{[(BENZYLAMINO)CARBONYL]AMINO}-2-HYDROXYPROPANOIC ACID
Experimental
Matched Name: … (2R)-3-{[(BENZYLAMINO)CARBONYL]AMINO}-2-HYDROXYPROPANOIC ACID …
Matched Iupac: … (2R)-3-[(benzylcarbamoyl)amino]-2-hydroxypropanoic acid …
Matched Iupac: … (2R)-3-[(benzylcarbamoyl)amino]-2-hydroxypropanoic acid …
Displaying drugs 2501 - 2525 of 3128 in total