Displaying drugs 2551 - 2575 of 3322 in total
Doxorubicin
Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970.[A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a primary alcohol group compared to the methyl group of daunorubicin. Although its detailed...
Approved
Investigational
Matched Description: … [A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain ... Hodgkin’s lymphoma, multiple myeloma, sarcoma, and pediatric cancers. ... generally thought to exert its effect through DNA intercalation, which eventually leads to DNA damage and …
Matched Salts name: … Doxorubicin hydrochloride …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Doxorubicin Hydrochloride ... DOXOrubicin Hydrochloride ... Doxorubicin hydrochloride …
Matched Salts name: … Doxorubicin hydrochloride …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Doxorubicin Hydrochloride ... DOXOrubicin Hydrochloride ... Doxorubicin hydrochloride …
Hydroxyzine
Hydroxyzine is a first-generation histamine H1-receptor antagonist of the dephenylmethane and piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties.[A1257,A187589] It was first developed in 1955, and has since remained a relatively common treatment for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. The active metabolite of hydroxyzine,...
Approved
Matched Description: … Hydroxyzine is a first-generation histamine H1-receptor antagonist of the dephenylmethane and ... piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties. ... for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. …
Matched Salts name: … Hydroxyzine hydrochloride …
Matched Categories: … Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … Hydroxyzine hydrochloride ... Hydroxyzine Hydrochloride ... HydrOXYzine hydrochloride …
Matched Salts name: … Hydroxyzine hydrochloride …
Matched Categories: … Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … Hydroxyzine hydrochloride ... Hydroxyzine Hydrochloride ... HydrOXYzine hydrochloride …
Bitolterol
Bitolterol mesylate was used to treat bronchospasms in asthma and COPD. It is a beta-2-adrenergic receptor agonist. Bitolterol was withdrawn from the market by Elan Pharmaceuticals in 2001.
Withdrawn
Matched Synonyms: … bis(4-methylbenzoic acid) 4-[2-(tert-butylamino)-1-hydroxyethyl]-1,2-phenylene ester …
Matched Description: … Bitolterol mesylate was used to treat bronchospasms in asthma and COPD. …
Matched Description: … Bitolterol mesylate was used to treat bronchospasms in asthma and COPD. …
rAAV1-CB-hAAT
rAAV1-CB-hAAT is a recombinant adeno-associated virus alpha 1-antitrypsin vector.
Investigational
Matched Synonyms: … recombinant adeno-associated virus alpha 1-antitrypsin vector …
Matched Description: … rAAV1-CB-hAAT is a recombinant adeno-associated virus alpha 1-antitrypsin vector. …
Matched Description: … rAAV1-CB-hAAT is a recombinant adeno-associated virus alpha 1-antitrypsin vector. …
Cefotiam
One of the cephalosporins that has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.
Approved
Investigational
Matched Synonyms: … dimethylamino-ethyl)-1H-tetrazol-5-ylsulfanylmethyl]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … ethyl]-1H-1,2,3,4-tetrazol-5-yl}sulfanyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … One of the cephalosporins that has a broad spectrum of activity against both gram-positive and gram-negative …
Matched Salts name: … Cefotiam hydrochloride …
Matched Iupac: … ethyl]-1H-1,2,3,4-tetrazol-5-yl}sulfanyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … One of the cephalosporins that has a broad spectrum of activity against both gram-positive and gram-negative …
Matched Salts name: … Cefotiam hydrochloride …
S-(N-hydroxy-N-bromophenylcarbamoyl)glutathione
Experimental
Matched Synonyms: … bromo-N-hydroxyanilino)-hydroxymethyl]sulfanyl-1-(carboxymethylamino)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid …
Matched Iupac: … bromophenyl)(hydroxy)amino](hydroxy)methyl]sulfanyl}-1-[(carboxymethyl)carbamoyl]ethyl]carbamoyl}butanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Iupac: … bromophenyl)(hydroxy)amino](hydroxy)methyl]sulfanyl}-1-[(carboxymethyl)carbamoyl]ethyl]carbamoyl}butanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Hyoscyamine
Hyoscyamine is a tropane alkaloid and the levo-isomer of atropine. It is commonly extracted from plants in the Solanaceae or nightshade family. Research into the action of hyoscyamine in published literature dates back to 1826. Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic...
Approved
Matched Synonyms: … [3(S)-endo]-α-(hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester …
Matched Description: … Hyoscyamine is a tropane alkaloid and the levo-isomer of [atropine]. ... [A228713] Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic …
Matched Mixtures name: … Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and Butabarbital ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide …
Matched Categories: … Alimentary Tract and Metabolism ... Belladonna and Derivatives, Plain ... hyoscyamine and psycholeptics …
Matched Description: … Hyoscyamine is a tropane alkaloid and the levo-isomer of [atropine]. ... [A228713] Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic …
Matched Mixtures name: … Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and Butabarbital ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide …
Matched Categories: … Alimentary Tract and Metabolism ... Belladonna and Derivatives, Plain ... hyoscyamine and psycholeptics …
Reltecimod
Reltecimod is under investigation in clinical trial NCT02469857 (Phase III Efficacy and Safety Study of AB103 in the Treatment of Patients With Necrotizing Soft Tissue Infections).
Investigational
Matched Synonyms: … D-alanyl-L-seryl-L-prolyl-L-methionyl-L-leucyl-L-valyl-L-alanyl-L-tyrosyl-L-aspartyl-D-alanine …
Matched Iupac: … methylbutanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-3-{[(1R)-1-carboxyethyl]carbamoyl}propanoic acid …
Matched Description: … Reltecimod is under investigation in clinical trial NCT02469857 (Phase III Efficacy and Safety Study …
Matched Salts name: … Reltecimod sodium …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Costimulatory and Inhibitory T-Cell Receptors …
Matched Iupac: … methylbutanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-3-{[(1R)-1-carboxyethyl]carbamoyl}propanoic acid …
Matched Description: … Reltecimod is under investigation in clinical trial NCT02469857 (Phase III Efficacy and Safety Study …
Matched Salts name: … Reltecimod sodium …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Costimulatory and Inhibitory T-Cell Receptors …
Piroxicam
A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its long half-life enables it to be administered once daily.
Approved
Investigational
Matched Description: … osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. ... non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Matched Products: … PIROXICAM ACIS 20MG …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Matched Products: … PIROXICAM ACIS 20MG …
Zingerone
Zingerone is a pungent component of ginger.
Experimental
Matched Synonyms: … Vanillyl acetone …
Cathinone
Cathinone is a monoamine alkaloid found in the shrub Catha edulis (Khat). Closely related to ephedrine, cathine and other amphetamines, it is probably the main contributor to the stimulant effect of Catha edulis. Cathinone differs from many other amphetamines in that its structure is a ketone. Other amphetamines to share...
Illicit
Matched Synonyms: … alpha-Aminopropiophenone …
Matched Description: … Closely related to ephedrine, cathine and other amphetamines, it is probably the main contributor to ... Other amphetamines to share this structure include the antidepressant bupropion and the stimulant methcathinone …
Matched Description: … Closely related to ephedrine, cathine and other amphetamines, it is probably the main contributor to ... Other amphetamines to share this structure include the antidepressant bupropion and the stimulant methcathinone …
Amitriptyline
Amitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961. Amitriptyline has been investigated in the treatment of pain-related conditions, attributed to its analgesic properties.
Approved
Matched Mixtures name: … Perphenazine and Amitriptyline Hydrochloride ... Perphenazine and Amitriptyline Hydrochloride ... Chlordiazepoxide and Amitriptyline Hydrochloride …
Matched Salts name: … Amitriptyline hydrochloride …
Matched Categories: … amitriptyline and psycholeptics ... Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … Amitriptyline Hydrochloride ... Amitriptyline hydrochloride ... AMITRIPTYLINE HYDROCHLORIDE …
Matched Salts name: … Amitriptyline hydrochloride …
Matched Categories: … amitriptyline and psycholeptics ... Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … Amitriptyline Hydrochloride ... Amitriptyline hydrochloride ... AMITRIPTYLINE HYDROCHLORIDE …
Formebolone
Formebolone, a derivative of androstane, is an anabolic androgenic steroid. It is on the list of substances prohibited by the Word Anti-Doping Agency, and is regularly screened for in athletes. It is also classified by the US Drug Enforcement Administration as Schedule III drug in the Controlled Substances Act. It...
Experimental
Illicit
Matched Synonyms: … 2-Formyl-17-alpha-methylandrosta-1,4-diene-11-alpha,17-beta-diol-3-one ... 2-Formyl-11-alpha-hydroxy-delta(sup 1)-methyltestosterone ... 11-alpha,17-beta-Dihydroxy-17-methyl-3-oxoandrosta-1,4-diene-2-carboxaldehyde …
Matched Description: … It is on the list of substances prohibited by the Word Anti-Doping Agency, and is regularly screened ... It has been used experimentally in the treatment of growth retardation, and has been noted to increase …
Matched Categories: … Testosterone and derivatives …
Matched Description: … It is on the list of substances prohibited by the Word Anti-Doping Agency, and is regularly screened ... It has been used experimentally in the treatment of growth retardation, and has been noted to increase …
Matched Categories: … Testosterone and derivatives …
Beludavimab
Beludavimab is under investigation in clinical trial NCT04746183 (AGILE (Early Phase Platform Trial for COVID-19)).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1 (246-ALANINE,340-LEUCINE,342-GLUTAMIC ACID,438-LEUCINE,444-SERINE), ANTI-(SEVERE ACUTE …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Erythropoietin
Erythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red blood cells. It works by promoting the division and differentiation of committed erythroid progenitors in the bone marrow [FDA Label]. Epoetin alfa (Epoge) was developed by Amgen Inc. in 1983 as the first rhEPO...
Approved
Matched Description: … The product contains the identical amino acid sequence of isolated natural erythropoietin and has the ... Epoetin alfa is a 165-amino acid erythropoiesis-stimulating glycoprotein produced in cell culture using ... and displays equivalent clinical efficacy, potency, and purity to the reference product [A7504]. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Intercellular Signaling Peptides and Proteins …
Matched Products: … Biopoin ... BIOPOIN 5000 IE /0.5ML SD ... BIOPOIN 1000 I E /0.5ML SD …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Intercellular Signaling Peptides and Proteins …
Matched Products: … Biopoin ... BIOPOIN 5000 IE /0.5ML SD ... BIOPOIN 1000 I E /0.5ML SD …
Raloxifene
Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation.[A4979,T28] Exhibiting tissue-specific effects distinct from estradiol, raloxifene is the first of the benzothiophene group of antiestrogens to be labelled a SERM....
Approved
Investigational
Matched Description: … uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation. ... generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and ... and it does not cause endometrial proliferation. …
Matched Salts name: … Raloxifene Hydrochloride …
Matched Categories: … Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Matched Products: … Raloxifene Hydrochloride ... Raloxifene hydrochloride …
Matched Salts name: … Raloxifene Hydrochloride …
Matched Categories: … Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Matched Products: … Raloxifene Hydrochloride ... Raloxifene hydrochloride …
Darigabat
Darigabat is under investigation in clinical trial NCT05941442 (A Study to Evaluate Efficacy, Safety, and Tolerability of Darigabat in Participants With Panic Disorder).
Investigational
Matched Synonyms: … 7-ethyl-4-(4'-(ethylsulfonyl)-6-fluoro-2'-methoxybiphenyl-3-yl)-7h-imidazo(4,5-c)-pyridazine ... 7h-imidazo(4,5-c)pyridazine, 7-ethyl-4-(4'-(ethylsulfonyl)-6-fluoro-2'-methoxy(1,1'-biphenyl)-3-yl)- …
Matched Description: … Darigabat is under investigation in clinical trial NCT05941442 (A Study to Evaluate Efficacy, Safety, and …
Matched Description: … Darigabat is under investigation in clinical trial NCT05941442 (A Study to Evaluate Efficacy, Safety, and …
Alfentanil
A short-acting opioid anesthetic and analgesic derivative of fentanyl. It produces an early peak analgesic effect and fast recovery of consciousness. Alfentanil is effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically ill patients.
Approved
Illicit
Matched Description: … A short-acting opioid anesthetic and analgesic derivative of fentanyl. ... It produces an early peak analgesic effect and fast recovery of consciousness. ... effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and …
Matched Salts name: … Alfentanil hydrochloride …
Matched Categories: … Fentanyl and fentanyl analogues …
Matched Products: … Alfentanil Hydrochloride …
Matched Salts name: … Alfentanil hydrochloride …
Matched Categories: … Fentanyl and fentanyl analogues …
Matched Products: … Alfentanil Hydrochloride …
Homatropine methylbromide
Homatropine methylbromide is a quaternary ammonium muscarinic acetylcholine receptor antagonist belonging to the group of medicines called anti-muscarinics. Homatropine is used to treat duodenal or stomach ulcers or intestine problems. It can be used together with antacids or other medicine in the treatment of peptic ulcer. It may also be...
Approved
Matched Synonyms: … 3-alpha-Hydroxy-8-methyl-1-alpha-H,5-alpha-H-tropanium bromide mandelate …
Matched Description: … It may also be used to prevent nausea, vomiting, and motion sickness. …
Matched Mixtures name: … Antitussive hydrocodone bitartrate and homatropine methylbromide ... Hydrocodone Bitartrate and Homatropine Methylbromide ... Hydrocodone Bitartrate and Homatropine Methylbromide …
Matched Categories: … Alimentary Tract and Metabolism ... Belladonna and Derivatives, Plain ... homatropine methylbromide and psycholeptics …
Matched Description: … It may also be used to prevent nausea, vomiting, and motion sickness. …
Matched Mixtures name: … Antitussive hydrocodone bitartrate and homatropine methylbromide ... Hydrocodone Bitartrate and Homatropine Methylbromide ... Hydrocodone Bitartrate and Homatropine Methylbromide …
Matched Categories: … Alimentary Tract and Metabolism ... Belladonna and Derivatives, Plain ... homatropine methylbromide and psycholeptics …
Papaverine
An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear,...
Approved
Investigational
Matched Description: … It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, ... mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and …
Matched Salts name: … Papaverine hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Papaverine and Derivatives …
Matched Products: … Papaverine Hydrochloride ... PAPAVERINE HYDROCHLORIDE ... Papaverine Hydrochloride Injection USP …
Matched Salts name: … Papaverine hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Papaverine and Derivatives …
Matched Products: … Papaverine Hydrochloride ... PAPAVERINE HYDROCHLORIDE ... Papaverine Hydrochloride Injection USP …
Naratriptan
Naratriptan is a triptan drug that is selective for the 5-hydroxytryptamine1 receptor subtype. It is typically used for the treatment of migraine headaches.
Approved
Investigational
Matched Salts name: … Naratriptan hydrochloride …
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … Naratriptan Hydrochloride …
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … Naratriptan Hydrochloride …
Pyridoxal phosphate
This is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (pyridoxamine).
Approved
Investigational
Nutraceutical
Matched Synonyms: … Pyridoxal 5-monophosphoric acid ester …
Matched Iupac: … [(4-formyl-5-hydroxy-6-methylpyridin-3-yl)methoxy]phosphonic acid …
Matched Description: … During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine ... phosphate (pyridoxamine). ... (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. …
Matched Mixtures name: … Levomefolate Calcium, Pyridoxal 5-phosphate, Methylcobalamin and Schizochytrium DHA Oil …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Matched Iupac: … [(4-formyl-5-hydroxy-6-methylpyridin-3-yl)methoxy]phosphonic acid …
Matched Description: … During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine ... phosphate (pyridoxamine). ... (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. …
Matched Mixtures name: … Levomefolate Calcium, Pyridoxal 5-phosphate, Methylcobalamin and Schizochytrium DHA Oil …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
(-)-menthol 1-propylene glycol carbonate
Experimental
Matched Synonyms: … Carbonic acid, 2-hydroxypropyl (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester …
L-Acetylleucine
Investigational
Matched Synonyms: … (s)-2-acetamido-4-methylpentanoic acid …
Matched Iupac: … (2S)-2-acetamido-4-methylpentanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Essential ... Amino Acids, Branched-Chain …
Matched Iupac: … (2S)-2-acetamido-4-methylpentanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Essential ... Amino Acids, Branched-Chain …
Displaying drugs 2551 - 2575 of 3322 in total