Displaying drugs 2601 - 2625 of 3032 in total
Cyclobenzaprine
Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961 and has been available for human use since 1977. It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from Amitriptyline by only a single double bond.[A185039,A184982] Since its approval, it has...
Approved
Matched Description: … Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961[A185039] and has been …
Matched Salts name: … Cyclobenzaprine hydrochloride …
Matched Products: … Cyclobenzaprine Hydrochloride ... Cyclobenzaprine hydrochloride …
Matched Salts name: … Cyclobenzaprine hydrochloride …
Matched Products: … Cyclobenzaprine Hydrochloride ... Cyclobenzaprine hydrochloride …
Melphalan
Melphalan is a nitrogen mustard or bischloroethylamine type alkylating agent. It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard.[A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. It is also used for high-conditioning before hematopoietic stem...
Approved
Matched Iupac: … (2S)-2-amino-3-{4-[bis(2-chloroethyl)amino]phenyl}propanoic acid …
Matched Description: … [A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. …
Matched Salts name: … Melphalan hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Products: … Melphalan Hydrochloride ... Melphalan hydrochloride …
Matched Description: … [A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. …
Matched Salts name: … Melphalan hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Products: … Melphalan Hydrochloride ... Melphalan hydrochloride …
Nicotinamide adenine dinucleotide phosphate
Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
Experimental
Matched Name: … Nicotinamide adenine dinucleotide phosphate …
Matched Iupac: … {[({[(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl …
Matched Description: … It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced ... Nicotinamide adenine dinucleotide phosphate. ... ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Enzymes and Coenzymes ... Adenine Nucleotides …
Matched Iupac: … {[({[(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl …
Matched Description: … It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced ... Nicotinamide adenine dinucleotide phosphate. ... ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Enzymes and Coenzymes ... Adenine Nucleotides …
Reveglucosidase alfa
Investigational
Matched Synonyms: … insulin-like growth factor ii fusion protein with glycyl-l-alanyl-l-prolyl-human lysosomal alpha-glucosidase (acid …
Beludavimab
Beludavimab is under investigation in clinical trial NCT04746183 (AGILE (Early Phase Platform Trial for COVID-19)).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1 (246-ALANINE,340-LEUCINE,342-GLUTAMIC ACID,438-LEUCINE,444-SERINE), ANTI-(SEVERE ACUTE …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Bendamustine
Bendamustine is a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL). Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups that covalently bond to other molecules. Through this function as an alkylating agent, bendamustine...
Approved
Investigational
Matched Iupac: … 4-{5-[bis(2-chloroethyl)amino]-1-methyl-1H-1,3-benzodiazol-2-yl}butanoic acid …
Matched Description: … a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia (CLL) and ... Through this function as an alkylating agent, bendamustine causes intra- and inter-strand crosslinks ... It is active against both active and quiescent cells, although the exact mechanism of action is unknown …
Matched Salts name: … Bendamustine hydrochloride ... Bendamustine hydrochloride monohydrate …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Acids, Acyclic ... Carboxylic Acids …
Matched Products: … Bendamustine Hydrochloride ... Bendamustine Hydrochloride for Injection ... Bendamustine Hydrochloride Kabi 25mg Powder for Concentrate for Solution for Infusion …
Matched Description: … a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia (CLL) and ... Through this function as an alkylating agent, bendamustine causes intra- and inter-strand crosslinks ... It is active against both active and quiescent cells, although the exact mechanism of action is unknown …
Matched Salts name: … Bendamustine hydrochloride ... Bendamustine hydrochloride monohydrate …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Acids, Acyclic ... Carboxylic Acids …
Matched Products: … Bendamustine Hydrochloride ... Bendamustine Hydrochloride for Injection ... Bendamustine Hydrochloride Kabi 25mg Powder for Concentrate for Solution for Infusion …
Bitolterol
Bitolterol mesylate was used to treat bronchospasms in asthma and COPD. It is a beta-2-adrenergic receptor agonist. Bitolterol was withdrawn from the market by Elan Pharmaceuticals in 2001.
Withdrawn
Matched Synonyms: … bis(4-methylbenzoic acid) 4-[2-(tert-butylamino)-1-hydroxyethyl]-1,2-phenylene ester …
Matched Description: … Bitolterol mesylate was used to treat bronchospasms in asthma and COPD. …
Matched Description: … Bitolterol mesylate was used to treat bronchospasms in asthma and COPD. …
Etoposide toniribate
Investigational
Matched Synonyms: … Carbonic acid, (2,2-dimethyl-1,3-dioxolan-4-yl)methyl 4-((5r,5ar,8ar,9s)-9-((4,6-o-(1r)-ethylidene-.beta ... 6-oxo-5,5a,6,8,8a,9-hexahydro-2h-furo(3',4':6,7)naphtho(2,3-d)(1,3)dioxol-5-yl)-2,6-dimethoxyphenyl carbonate …
Matched Iupac: … .0^{11,15}]hexadeca-1(9),2,7-trien-10-yl]-2,6-dimethoxyphenyl (2,2-dimethyl-1,3-dioxolan-4-yl)methyl carbonate …
Matched Iupac: … .0^{11,15}]hexadeca-1(9),2,7-trien-10-yl]-2,6-dimethoxyphenyl (2,2-dimethyl-1,3-dioxolan-4-yl)methyl carbonate …
Technetium Tc-99m pertechnetate
Technetium Tc-99m pertechnetate is a radiopharmaceutical diagnostic agent composed of an oxoanion with the chemical formula TcO4-. Pertechnetate has a wide variety of uses within nuclear medicine as it distributes within the body to a similar extent as iodine. It also concentrates in the thyroid gland, salivary glands, gastric mucosa,...
Approved
Investigational
Matched Description: … It also concentrates in the thyroid gland, salivary glands, gastric mucosa, and choroid plexus. ... , salivary gland, urinary bladder (for detection of vesico-ureteral reflux), and the nasolacrimal drainage ... technetium exits the generator in the form of the pertechnetate ion, TcO4−, which can be extracted and …
Matched Mixtures name: … GENERADOR DE SOLUCION INYECTABLE DE PERTECNETATO (99MTC) DE SODIO. 2-50GBQ …
Matched Salts name: … Technetium Tc-99m sodium pertechnetate …
Matched Categories: … Indicators and Reagents ... Thyroid Diagnostic Radiopharmaceuticals …
Matched Products: … Sodium Pertechnetate 99mtc Injection …
Matched Mixtures name: … GENERADOR DE SOLUCION INYECTABLE DE PERTECNETATO (99MTC) DE SODIO. 2-50GBQ …
Matched Salts name: … Technetium Tc-99m sodium pertechnetate …
Matched Categories: … Indicators and Reagents ... Thyroid Diagnostic Radiopharmaceuticals …
Matched Products: … Sodium Pertechnetate 99mtc Injection …
L-Acetylleucine
Investigational
Matched Synonyms: … (s)-2-acetamido-4-methylpentanoic acid …
Matched Iupac: … (2S)-2-acetamido-4-methylpentanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Essential ... Amino Acids, Branched-Chain …
Matched Iupac: … (2S)-2-acetamido-4-methylpentanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Essential ... Amino Acids, Branched-Chain …
5'-S-methyl-5'-thioadenosine
Experimental
Matched Synonyms: … 5'-Deoxy-5'-(methylthio)adenosine …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Nucleic Acids, Nucleotides, and Nucleosides ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Dicarboxylic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Nucleic Acids, Nucleotides, and Nucleosides ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Dicarboxylic …
2-METHYLTHIO-N6-ISOPENTENYL-ADENOSINE-5'-MONOPHOSPHATE
Experimental
Matched Name: … 2-METHYLTHIO-N6-ISOPENTENYL-ADENOSINE-5'-MONOPHOSPHATE …
Matched Iupac: … acid ... ,5R)-3,4-dihydroxy-5-{6-[(3-methylbutyl)amino]-2-(methylsulfanyl)-9H-purin-9-yl}oxolan-2-yl]methoxy}phosphonic …
Matched Iupac: … acid ... ,5R)-3,4-dihydroxy-5-{6-[(3-methylbutyl)amino]-2-(methylsulfanyl)-9H-purin-9-yl}oxolan-2-yl]methoxy}phosphonic …
Citicoline
Citicoline is a donor of choline in biosynthesis of choline-containing phosphoglycerides. It has been investigated for the treatment, supportive care, and diagnosis of Mania, Stroke, Hypomania, Cocaine Abuse, and Bipolar Disorder, among others.
Approved
Experimental
Matched Iupac: … (2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl …
Matched Description: … , Cocaine Abuse, and Bipolar Disorder, among others. ... It has been investigated for the treatment, supportive care, and diagnosis of Mania, Stroke, Hypomania …
Matched Salts name: … Citicoline sodium …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … CITICOLINE SODIUM …
Matched Description: … , Cocaine Abuse, and Bipolar Disorder, among others. ... It has been investigated for the treatment, supportive care, and diagnosis of Mania, Stroke, Hypomania …
Matched Salts name: … Citicoline sodium …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … CITICOLINE SODIUM …
Oseltamivir
Oseltamivir (marketed as the product TamifluⓇ), is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A (including pandemic H1N1) and B. Oseltamivir exerts its antiviral activity by inhibiting the activity of the viral neuraminidase enzyme found on the surface of the virus, which...
Approved
Matched Synonyms: … 1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-, ethyl ester, (3R-(3alpha …
Matched Description: … (marketed as the product TamifluⓇ), is an antiviral neuraminidase inhibitor used for the treatment and ... prophylaxis of infection with influenza viruses A (including pandemic H1N1) and B. ... that early antiviral treatment can shorten the duration of fever and illness symptoms, and may reduce …
Matched Description: … (marketed as the product TamifluⓇ), is an antiviral neuraminidase inhibitor used for the treatment and ... prophylaxis of infection with influenza viruses A (including pandemic H1N1) and B. ... that early antiviral treatment can shorten the duration of fever and illness symptoms, and may reduce …
Famciclovir
Famciclovir, marketed as Famvir by Novartis, is a guanine analogue used to treat herpes virus infections. It is most commonly used to treat herpes zoster (shingles). Famciclovir is a prodrug of penciclovir with higher oral bioavailability.
Approved
Investigational
Matched Synonyms: … acetic acid 2-acetoxymethyl-4-(2-amino-purin-9-yl)-butyl ester …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Barzolvolimab
Barzolvolimab is under investigation in clinical trial NCT06455202 (A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (CSU)).
Investigational
Matched Synonyms: … Immunoglobulin G1 [233-alanine,234-glutamine,251-tyrosine,253-threonine,255-glutamic acid,321-glutamine …
Pyridoxal phosphate
This is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (pyridoxamine).
Approved
Investigational
Nutraceutical
Matched Synonyms: … Pyridoxal 5-monophosphoric acid ester …
Matched Iupac: … [(4-formyl-5-hydroxy-6-methylpyridin-3-yl)methoxy]phosphonic acid …
Matched Description: … (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. ... This is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters ... During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine …
Matched Mixtures name: … Levomefolate Calcium, Pyridoxal 5-phosphate, Methylcobalamin and Schizochytrium DHA Oil …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Matched Iupac: … [(4-formyl-5-hydroxy-6-methylpyridin-3-yl)methoxy]phosphonic acid …
Matched Description: … (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. ... This is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters ... During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine …
Matched Mixtures name: … Levomefolate Calcium, Pyridoxal 5-phosphate, Methylcobalamin and Schizochytrium DHA Oil …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Flurazepam
A benzodiazepine derivative used mainly as a hypnotic.
Approved
Illicit
Investigational
Matched Salts name: … Flurazepam hydrochloride …
Matched Categories: … Benzodiazepines and benzodiazepine derivatives ... Hypnotics and Sedatives …
Matched Products: … Flurazepam Hydrochloride …
Matched Categories: … Benzodiazepines and benzodiazepine derivatives ... Hypnotics and Sedatives …
Matched Products: … Flurazepam Hydrochloride …
N-Alpha-(2-Naphthylsulfonyl)-N(3-Amidino-L-Phenylalaninyl)Isopipecolinic Acid Methyl Ester
Experimental
Matched Name: … N-Alpha-(2-Naphthylsulfonyl)-N(3-Amidino-L-Phenylalaninyl)Isopipecolinic Acid Methyl Ester …
(S)-2-Amino-3-(6h-Selenolo[2,3-B]-Pyrrol-4-Yl)-Propionic Acid
Experimental
Matched Name: … (S)-2-Amino-3-(6h-Selenolo[2,3-B]-Pyrrol-4-Yl)-Propionic Acid …
Matched Iupac: … (2S)-2-amino-3-{6H-selenopheno[2,3-b]pyrrol-4-yl}propanoic acid …
Matched Categories: … Selenium Compounds …
Matched Iupac: … (2S)-2-amino-3-{6H-selenopheno[2,3-b]pyrrol-4-yl}propanoic acid …
Matched Categories: … Selenium Compounds …
5-[1-(Acetylamino)-3-Methylbutyl]-2,5-Anhydro-3,4-Dideoxy-4-(Methoxycarbonyl)Pentonic Acid
Experimental
Matched Name: … 5-[1-(Acetylamino)-3-Methylbutyl]-2,5-Anhydro-3,4-Dideoxy-4-(Methoxycarbonyl)Pentonic Acid …
Matched Iupac: … (2R,4R,5R)-5-[(1S)-1-acetamido-3-methylbutyl]-4-(methoxycarbonyl)oxolane-2-carboxylic acid …
Matched Iupac: … (2R,4R,5R)-5-[(1S)-1-acetamido-3-methylbutyl]-4-(methoxycarbonyl)oxolane-2-carboxylic acid …
(S)-2-Amino-3-(4h-Selenolo[3,2-B]-Pyrrol-6-Yl)-Propionic Acid
Experimental
Matched Name: … (S)-2-Amino-3-(4h-Selenolo[3,2-B]-Pyrrol-6-Yl)-Propionic Acid …
Matched Iupac: … (2S)-2-amino-3-{4H-selenopheno[3,2-b]pyrrol-6-yl}propanoic acid …
Matched Categories: … Selenium Compounds …
Matched Iupac: … (2S)-2-amino-3-{4H-selenopheno[3,2-b]pyrrol-6-yl}propanoic acid …
Matched Categories: … Selenium Compounds …
4-O-{4,6-O-[(1S)-1-Carboxyethylidene]-β-D-mannopyranosyl}-D-glucopyranuronic acid
Experimental
Matched Name: … 4-O-{4,6-O-[(1S)-1-Carboxyethylidene]-β-D-mannopyranosyl}-D-glucopyranuronic acid …
Matched Iupac: … dihydroxy-2-methyl-hexahydro-2H-pyrano[3,2-d][1,3]dioxin-6-yl]oxy}-4,5,6-trihydroxyoxane-2-carboxylic acid …
Matched Iupac: … dihydroxy-2-methyl-hexahydro-2H-pyrano[3,2-d][1,3]dioxin-6-yl]oxy}-4,5,6-trihydroxyoxane-2-carboxylic acid …
5-ACETAMIDO-5,6-DIHYDRO-4-HYDROXY-6-ISOBUTOXY-4H-PYRAN-2-CARBOXYLIC ACID
Experimental
Matched Name: … 5-ACETAMIDO-5,6-DIHYDRO-4-HYDROXY-6-ISOBUTOXY-4H-PYRAN-2-CARBOXYLIC ACID …
Matched Iupac: … (2R,3R,4S)-3-acetamido-4-hydroxy-2-(2-methylpropoxy)-3,4-dihydro-2H-pyran-6-carboxylic acid …
Matched Iupac: … (2R,3R,4S)-3-acetamido-4-hydroxy-2-(2-methylpropoxy)-3,4-dihydro-2H-pyran-6-carboxylic acid …
3-[5-(2-nitropent-1-en-1-yl)furan-2-yl]benzoic acid
Experimental
Matched Name: … 3-[5-(2-nitropent-1-en-1-yl)furan-2-yl]benzoic acid …
Matched Iupac: … 3-{5-[(1Z)-2-nitropent-1-en-1-yl]furan-2-yl}benzoic acid …
Matched Iupac: … 3-{5-[(1Z)-2-nitropent-1-en-1-yl]furan-2-yl}benzoic acid …
Displaying drugs 2601 - 2625 of 3032 in total