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Displaying drugs 2701 - 2725 of 9511 in total

Iodixanol

Iodixanol is a nonionic hydrophilic compound commonly used as a contrast agent during coronary angiography, particularly in individuals with renal dysfunction, as it is believed to be less toxic to the kidneys than most other intravascular contrast agents.
Approved
Matched Categories: … Diagnostic Uses of Chemicals …

Mangafodipir

Mangafodipir is a contrast agent used as a diagnostic tool administered intravenously to enhance contrast in magnetic resonance imaging (MRI) of the liver and pancreas. This drug is made up of paramagnetic manganese (II) ions combined with the chelating agent fodipir (dipyridoxyl diphosphate, DPDP). Manganese absorption into the tissues that...
Approved
Investigational
Withdrawn
Matched Description: … Enhanced contrast by mangafodipir improves visualization and detection of lesions of the liver formed ... diagnostic tool administered intravenously to enhance contrast in magnetic resonance imaging (MRI) of ... This drug is made up of paramagnetic manganese (II) ions combined with the chelating agent _fodipir_ …
Matched Categories: … Diagnostic Uses of Chemicals …

Ioversol

Ioversol is a non-ionic compound with a tri-iodinated benzene ring used as a contrast dye in diagnostic procedures to visualize different types of organs and tissues. Iodine has a high atomic density, which gives it the ability to attenuate X-rays. The intravascular administration of iodine compounds, such as ioversol, enhances...
Approved
Matched Description: … of internal structures. ... between vessels in the path of the flow of the contrast medium and normal tissue, allowing the visualization ... tri-iodinated benzene ring used as a contrast dye in diagnostic procedures to visualize different types of …
Matched Categories: … Diagnostic Uses of Chemicals …

Escitalopram

Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic citalopram. It is used to restore serotonergic function in the treatment of depression and anxiety.[L8513,L8516,L8522] Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and is responsible for the vast majority of citalopram’s clinical activity, with...
Approved
Matched Description: … that the R-enantiomer of racemic citalopram actively dampens the activity of escitalopram rather than ... [L8513,L8516,L8522] Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer ... [A185420] It is used to restore serotonergic function in the treatment of depression and anxiety. …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Haemophilus influenzae type B capsular polysaccharide meningococcal outer membrane protein conjugate antigen

Haemophilus influenzae type b capsular polysaccharide meningococcal outer membrane protein conjugate antigen is a vaccine containing outer membrane antigen extracted from Haemophilus influenzae.
Approved
Investigational

Atazanavir

Atazanavir (formerly known as BMS-232632) is an antiretroviral drug of the protease inhibitor (PI) class. Like other antiretrovirals, it is used to treat infection of human immunodeficiency virus (HIV). Atazanavir is distinguished from other PIs in that it can be given once daily (rather than requiring multiple doses per day)...
Approved
Investigational
Matched Description: … Like other antiretrovirals, it is used to treat infection of human immunodeficiency virus (HIV). ... Atazanavir (formerly known as BMS-232632) is an antiretroviral drug of the protease inhibitor (PI) class ... requiring multiple doses per day) and has lesser effects on the patient's lipid profile (the amounts of …
Matched Mixtures name: … ANCEF ® R ... ZANAVIR-R ... ANCEF ® R …
Matched Categories: … Antivirals used in combination for the treatment of HIV infections …

Nalidixic acid

Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.
Approved
Investigational
Matched Description: … It is an inhibitor of the A subunit of bacterial DNA gyrase. …

Telaprevir

Telaprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Withdrawn
Matched Description: … Subtitutions at amino acid positions 155, 156, or 168 are known to confer resistance. ... alter the affinity of the drug for NS3/4A or the activity of the enzyme itself. ... another class of DAAs [A19593]. …
Matched Categories: … Antivirals for treatment of HCV infections …

Leniolisib

Leniolisib is a potent and selective inhibitor of phosphoinositide 3-kinase δ (PI3Kδ). The FDA approved leniolisib on March 24, 2023, making it the first treatment for activated phosphoinositide 3-kinase delta syndrome (APDS). APDS is a primary immunodeficiency caused by mutations in genes encoding the PI3Kδ, thereby increasing the activity of...
Approved
Investigational
Matched Description: … Leniolisib is a potent and selective inhibitor of phosphoinositide 3-kinase δ (PI3Kδ). ... primary immunodeficiency caused by mutations in genes encoding the PI3Kδ, thereby increasing the activity of …

Dydrogesterone

A synthetic progestational hormone with no androgenic or estrogenic properties. Unlike many other progestational compounds, dydrogesterone produces no increase in temperature and does not inhibit ovulation.
Approved
Investigational
Withdrawn
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Risedronic acid

Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Investigational
Matched Description: … Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of ... It functions by preventing resorption of bone[FDA Label][A959]. …
Matched Categories: … Drugs for Treatment of Bone Diseases …

Lisdexamfetamine

Lisdexamfetamine is a prodrug of dextroamphetamine, a central nervous system stimulant known as d-amphetamine, covalently attached to the naturally occurring amino acid L-lysine. Lisdexamfetamine is the first chemically formulated prodrug stimulant and was first approved by the FDA in April 2008. It was also approved by Health Canada in February...
Approved
Investigational
Matched Description: … Lisdexamfetamine is a prodrug of [dextroamphetamine], a central nervous system stimulant known as d-amphetamine …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Amobarbital

A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
Approved
Illicit
Matched Description: … Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with …
Matched Categories: … combinations of barbiturates …

Nomegestrol

Nomegestrol is an ingredient in the EMA-authorised product Zoely.
Approved
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Pentetreotide

Pentetreotide has been used in trials studying the diagnosis of Cushing's syndrome.
Approved
Investigational
Matched Description: … Pentetreotide has been used in trials studying the diagnosis of Cushing's syndrome. …
Matched Categories: … Diagnostic Uses of Chemicals …

Afamelanotide

Afamelanotide is a first-in-class, synthetic, 13-amino acid peptide analogue of the endogenous alpha melanocyte-stimulating hormone (α-MSH). It differs structurally from its endogenous counterpart by only two amino acids - these structural differences improve biological efficacy by imparting a greater affinity for its target and a longer biological half-life.[A187202,A187205] Afamelanotide is...
Approved
Investigational
Matched Description: … Afamelanotide is a first-in-class, synthetic, 13-amino acid peptide analogue of the endogenous alpha ... [A187202,A187205] Afamelanotide is currently the only approved drug therapy used in the management of …
Matched Categories: … Melanocortin 1 Receptor (MC1-R) Agonists …

Duloxetine

Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. Duloxetine first received approval from the FDA in August, 2004 as Cymbalta for the treatment of Major Depressive Disorder. It has since received approval for a...
Approved
Matched Description: … [L6454] It has since received approval for a variety of indications including the treatment of neuropathic ... Duloxetine continues to be investigated for the treatment of pain in cancer, surgery, and more. ... A178741] Duloxetine first received approval from the FDA in August, 2004 as Cymbalta for the treatment of …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … DUAX-R …

Reserpine

An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool,...
Approved
Investigational
Withdrawn
Matched Description: … An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. ... 1 mg of reserpine. ... Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines …
Matched Mixtures name: … Renese-R …

Pilocarpine

A naturally occurring alkaloid derived from the Pilocarpus plants, pilocarpine is a muscarinic acetylcholine agonist.[A262016, A262036] Pilocarpine is associated with parasympathomimetic effects by selectively working on muscarinic receptors. Pilocarpine is used to treat dry mouth and various ophthalmic conditions, including elevated intraocular pressure and glaucoma. The usage of glaucoma by...
Approved
Investigational
Matched Description: … The usage of glaucoma by pilocarpine dates back to 1875.[A262041] …

Mumps virus strain B level jeryl lynn live antigen

Mumps virus strain B level jeryl lynn live antigen is a live attenuated virus vaccine for subcutenous injection. It is an active immunization against mumps, which is a common childhood disease.
Approved
Investigational
Matched Mixtures name: … M-M-R II ... M-M-R II ... M-M-R II …

Enoxacin

A broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.
Approved
Investigational
Matched Categories: … Metabolic Side Effects of Drugs and Substances …

Pargyline

Pargyline is a monoamine oxidase inhibitor with antihypertensive properties.
Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Sulfadimethoxine

Sulfadimethoxine is a sulfonamide antibiotic. Sulfadimethoxine is used to treat many infections, including treatment of respiratory, urinary tract, enteric, and soft tissue infections. It is most frequently used in veterinary medicine, although it is approved in some countries for use in humans. Sulfadimethoxine inhibits bacterial synthesis of folic acid (pteroylglutamic...
Approved
Vet approved
Withdrawn
Matched Description: … Sulfadimethoxine is used to treat many infections, including treatment of respiratory, urinary tract, ... Sulfadimethoxine inhibits bacterial synthesis of folic acid (pteroylglutamic acid) from para-aminobenzoic ... In the US, sulfadimethoxine is one of the products that have been withdrawn or removed from the market …
Matched Categories: … combinations of sulfonamides …

Udenafil

Udenafil is a new phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED). It has been approved in South Korea and will be marketed under the brand name Zydena. It is not yet approved for use in the U.S., E.U., or Canada.
Approved
Investigational
Matched Categories: … combinations of sulfonamides …

Ditiocarb zinc

Ditiocarb zinc, also known as Diethyldithiocarbamic acid zinc salt, is a known chelator for copper and zinc. It also a dermatological sensitizer and allergen. Sensitivity to ditiocarb zinc may be identified with a clinical patch test.
Approved
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Displaying drugs 2701 - 2725 of 9511 in total