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Displaying drugs 251 - 275 of 712 in total

AB-201

AB-201 is a CAR-NK cell therapy targeted against HER2. It is under investigation for the treatment of HER2-positive cancers, including breast and gastric carcinomas.
Investigational
Matched Synonyms: … allogeneic cord blood-derived NK cells that have been genetically modified to express a HER2-directed CAR and …
Matched Description: … [L48340] It is under investigation for the treatment of HER2-positive cancers, including breast and gastric …

OTL-102

OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human gp91phox gene. It is being investigated for the treatment of X-linked chronic granulomatous disease.
Investigational
Matched Synonyms: … Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced …
Matched Description: … OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells …

Haemophilus influenzae type B strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen

Haemophilus influenzae type b strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen is an active immunization as a booster dose given intramuscularly to pediatric patients who have received a primary series with a Haemophilus b Conjugate Vaccine that is licensed for primarly immunization. The vaccine contains Haemophilus b capsular polysaccharide...
Approved
Investigational
Matched Synonyms: … Haemophilus influenzae type B-PRP and tetanus toxoid conjugate (PRP-T) …
Matched Description: … These are heat inactivated and purified. …

Apadamtase alfa

Thrombotic thrombocytopenic purpura (TTP) is a rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and various degrees of organ damage. It may be inherited (congenital TTP; cTTP) or acquired due to autoantibodies (immune-mediated TTP; iTTP), although cTTP accounts for <5% of all cases of TTP. Patients with cTTP...
Approved
Investigational
Matched Synonyms: … Recombinant disintegrin and metalloprotease with thrombospondin type 1 motifs …
Matched Description: … rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and ... Patients with cTTP have a severe deficiency of a plasma metalloproteinase called ADAMTS13 (a disintegrin and ... thrombospondin type 1 motif, member 13), which is responsible for cleaving large von Willebrand factor multimers and …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... apadamtase alfa and cinaxadamtase alfa …

Rosa centifolia flower oil

Rosa centifolia flower oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Rosa Centifolia Flower Water ... Rosa Centifolia Flower Volatile Oil …
Matched Name: … Rosa centifolia flower oil …
Matched Description: … Rosa centifolia flower oil is a plant/plant extract used in some OTC (over-the-counter) products. …

Tarlatamab

Tarlatamab is a first-in-class T-cell engager used to treat extensive-stage small cell lung cancer. It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed across various SCLC disease stages...
Approved
Investigational
Matched Synonyms: … Immunoglobulin scfv-scfv-scfc, anti-(homo sapiens dll3 (delta-like ligand 3)) and anti-(homo sapiens ... cd3e (cd3 epsilon, leu-4)), monoclonal antibody single chain (scfv)2-scfc, bispecific …
Matched Description: … and delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed ... across various SCLC disease stages and treatment statuses. ... [L50748] It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells …
Matched Categories: … Amino Acids, Peptides, and Proteins ... CD3-directed Antibody …

Butylidenephthalide

Investigational
Matched Synonyms: … 3-butylidenephthalide, mixture of cis and trans isomers …

OTL-203

OTL-203 is an autologous CD34+ enriched cell therapy that contains hematopoietic stem and progenitor cells transduced ex-vivo using a lentiviral vector encoding alpha-L-iduronidase gene.
Investigational
Matched Synonyms: … Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced …
Matched Description: … OTL-203 is an autologous CD34+ enriched cell therapy that contains hematopoietic stem and progenitor …

Methylcellulose

Methyl cellulose polymer consisting of numerous linked glucose molecules used as a stabiliser, thickener and emulsifier for foodstuffs and cosmetics. The Degree of Substitution (DS) of a given form of methyl cellulose is defined as the average number of substituted hydroxyl groups per glucose with a theoretical maximum of 3,...
Approved
Matched Description: … emulsifier for foodstuffs and cosmetics. ... Like cellulose, it is not digestible, not toxic, and not allergenic ... Methyl cellulose polymer consisting of numerous linked glucose molecules used as a stabiliser, thickener and …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Foster and Thrive Fiber Laxative 188 …

Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine

Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine is used to prevent invasive meningococcal disease, which is caused by bacteria Neisseria meningitidis entering the bloodstream and invading the blood-brain barrier to cause a variety of infections such as septicemia, meningitis, and pneumonia. Several serogroups of N....
Approved
Matched Name: … Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine …
Matched Description: … Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine is used ... meningococcal disease, which is caused by bacteria _Neisseria meningitidis_ entering the bloodstream and ... invading the blood-brain barrier to cause a variety of infections such as septicemia, meningitis, and …

Aloe vera leaf

Aloe describes a genus including over 500 species of flowering succulent plants that grow in the Southern peninsula and various islands. Aloe vera, or Aloe barbadensis miller, is the most common species of Aloe that is cultivated for agricultural and medical purposes. It is a perennial succulent xerophyte with elongated...
Experimental
Matched Synonyms: … Aloe vera leaf juice ... Aloe vera leaf powder ... Aloe vera leaf extract …
Matched Name: … Aloe vera leaf …
Matched Description: … While aloe vera has a long history of commercial uses, it is still widely used in cosmetic, food and ... The use of aloe vera in constipation, inflammatory disorders, cancer, ulcer, and diabetes has also been ... and medical purposes. …
Matched Mixtures name: … Mousturizing Gloves and Socks ... Aloe Vera Sprayer …
Matched Products: … Ramosu Aloe Vera Leaf Extract 100 ... Aloe Vera Gel …

Tavokinogene telseplasmid

Tavokinogene telseplasmid consists of a DNA Plasmid Vector Encoding IL-12.
Investigational
Matched Synonyms: … Dna plasmid containing genes coding for the human interleukin 12 (il-12) p35 and p40 subunits that are ... separated by an internal ribosomal entry site (ires) and under the control of a single cytomegalovirus …

Azercabtagene zapreleucel

Investigational
Matched Synonyms: … Adult allogeneic CD4+ and CD8+ enriched T cells transduced with an anti-CD19 chimeric antigen receptor ... Adult allogeneic CD4+ and CD8+ enriched T cells, gene edited through the electroporati …

Ergidina

Ergidina is a recombinant human minibody against complement component C5 fused with RGD-motif.
Investigational
Matched Synonyms: … Neutralizing scFv dimer to C5 fused at the C terminal end to the Fc domains of human IgG1 and the cyclic …

Quinoline Yellow WS

Experimental
Matched Synonyms: … D and C Yellow No. 10 …

Naproxen

Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994. It can effectively manage acute pain as well as pain related to rheumatic diseases, and has a well studied adverse effect profile. Given its...
Approved
Vet approved
Matched Description: … prescription use in 1976 and then for over-the-counter (OTC) use in 1994. ... Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for ... [A178975] It can effectively manage acute pain as well as pain related to rheumatic diseases, and has …
Matched Mixtures name: … All Night Pain Relief PM ... Equate All Night Pain Relief ... Topcare All Night Pain Relief PM …
Matched Categories: … naproxen and misoprostol ... sumatriptan and naproxen ... naproxen and esomeprazole ... naproxen and diphenhydramine ... Antiinflammatory and Antirheumatic Products …
Matched Products: … Up and Up Naproxen sodium ... Back and Muscle Pain ... Aleve Back and Muscle Pain …

Tioconazole

Tioconazole is an imidazole antifungal used to treat fungal and yeast infections. Topical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus". Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane. In...
Approved
Matched Description: … Tioconazole is an imidazole antifungal used to treat fungal and yeast infections. ... Topical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus …
Matched Categories: … Imidazole and Triazole Derivatives ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Metabolic Side Effects of Drugs and Substances ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Up and up tioconazole 1 ... Foster and Thrive Tioconazole …

Calcium carbonate

Calcium carbonate is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. Calcium carbonate may also...
Approved
Investigational
Matched Description: … An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. …
Matched Mixtures name: … OB Complete Gold ... Good Night/pm Formula Tab ... Mylanta Coat and Cool …
Matched Categories: … Antacids and Adsorbents ... Alimentary Tract and Metabolism ... ascorbic acid (vit C) and calcium …
Matched Products: … CALCIUM VERLA 600MG ... HEB Lime and Berry Antacid Chews ... Tums Chewy Bites Orange and Cream ES …

Leuprolide

Leuprolide is a synthetic 9-residue peptide analogue of gonadotropin-releasing hormone (GnRH). Unlike the endogenous decapeptide GnRH, leuprolide contains a single D-amino acid (D-leucyl) residue, which helps to increase its circulating half-life from three to four minutes to approximately three hours. As a GnRH mimic, leuprolide is capable of binding to...
Approved
Investigational
Matched Description: … downstream modulation of both gonadotropin hormone and sex steroid levels. ... [A203222] As a GnRH mimic, leuprolide is capable of binding to the GnRH receptor (GnRHR) and inducing ... [L13850] Since this initial approval, various long-acting intramuscular and subcutaneous products have …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones and Related Agents ... leuprorelin and bicalutamide ... Antineoplastic and Immunomodulating Agents …
Matched Products: … POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 45mg ... POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 7.5mg ... POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 22.5mg …

Loratadine

Loratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis. A lack of sedative and CNS adverse effects make loratadine, along with other second generation antihistamines, preferable over their 1st generation counterparts in many clinical situations.
Approved
Investigational
Matched Description: … [A176435] A lack of sedative and CNS adverse effects make loratadine, along with other second generation …
Matched Mixtures name: … Loratadine and Pseudoephedrine ... Up and Up allergy and congestion relief ... Loratadine and Pseudoephedrine …
Matched Categories: … Loratadine and derivatives …
Matched Products: … Vicks QlearQuil All Day And All Night 24 Hour Allergy Relief ... Up and Up Allergy Relief ... Up and Up Childrens Allergy Relief …

Glyceryl monostearate

Glycerol monostearate, commonly known as GMS, is the glycerol ester of stearic acid . It is commonly used as an emulsifier in foods.
Experimental
Matched Synonyms: … Geleol mono and diglycerides …

Oxametacin

Experimental
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … FLOGAR …

Cinnamon leaf oil

Experimental
Matched Synonyms: … Cinnamomum verum leaf essential oil ... Cinnamomum zeylanicum leaf oil …
Matched Name: … Cinnamon leaf oil …

Miconazole

Miconazole is a broad-spectrum azole antifungal with some activity against Gram-positive bacteria as well. It is widely used to treat mucosal yeast infections, including both oral and vaginal infections; although intravenous miconazole is no longer available, a wide variety of suppositories, creams, gels, and tablet-based products are available.[L14021, L14024, L14027,...
Approved
Investigational
Vet approved
Matched Description: … [A203636] It is widely used to treat mucosal yeast infections, including both oral and vaginal infections ... although intravenous miconazole is no longer available, a wide variety of suppositories, creams, gels, and ... [A203636, A203639] Miconazole was first synthesized in 1969 and first granted FDA approval on January …
Matched Mixtures name: … Up and Up Miconazole 1 ... Up and Up Miconazole 1 ... Up and Up Miconazole 1 …
Matched Categories: … Imidazole and Triazole Derivatives ... Vaginal Creams, Foams, and Jellies ... Genito Urinary System and Sex Hormones ... Antiinfectives and Antiseptics for Local Oral Treatment ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Up and Up Miconazole 7 ... Soothe And Cool Treat ... Up and Up Jock Itch Relief …

Propylene glycol

A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
Approved
Investigational
Matched Description: … A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations. …
Matched Mixtures name: … Systane Day and Night Value Pack ... Systane Day and Night Value Pack ... Aloe Vera Gel …
Matched Products: … Eyelash and Eyebrow Lengthener …
Displaying drugs 251 - 275 of 712 in total