Advanced Filter

Filter by Group

Filter by Market Availability

Clear
Displaying drugs 251 - 275 of 10683 in total

Upadacitinib

Upadacitinib is an oral Janus kinase (JAK)1-selective inhibitor and a disease-modifying antirheumatic drug (DMARD) used in the treatment of rheumatoid arthritis to slow down disease progression. Rheumatoid arthritis is a chronic autoimmune inflammatory disease affecting the peripheral joints. It is characterized by synovial inflammation and hyperplasia, autoantibody production, cartilage damage...
Approved
Investigational
Matched Description: … [A189165] The FDA approved upadacitinib in August 2019 and it is used for the treatment of active ... oral Janus kinase (JAK)1-selective inhibitor and a disease-modifying antirheumatic drug (DMARD) used in ... [A189171] The etiology of the disease is mostly unknown; however, the role of JAK as a driver of immune-mediated …

Streptococcus pneumoniae type 9n capsular polysaccharide antigen

Streptococcus pneumoniae type 9n capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 9n of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Description: … vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 9n of …
Matched Mixtures name: … PNEUMOVAX 23 Injektionslösung in einer Fertigspritze ... PNEUMOVAX 23 Injektionslösung in einer Durchstechflasche …

Thiosulfuric acid

Thiosulfuric acid is available in its salt forms sodium thiosulfate and sodium thiosulfate pentahydrate. Sodium thiosulfate is part of the World Health Organization’s list of essential medicines, and it has a variety of industrial uses, including food preservative, water de-chlorinator and paper pulp bleaching agent. Sodium thiosulfate is rapidly degraded...
Approved
Investigational
Matched Description: … ] and it is frequently used in conjunction with sodium nitrite (a salt form of [nitrous acid]). ... Thiosulfuric acid is available in its salt forms sodium thiosulfate and sodium thiosulfate pentahydrate ... [A252827] Sodium thiosulfate is rapidly degraded in the stomach; therefore, it is normally administered …
Matched Salts cas: … 7772-98-7 ... 10102-17-7 …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Poliovirus type 2 antigen (formaldehyde inactivated)

Poliovirus type 2 antigen is a suspension of poliovirus Type 2 (MEF-1) used in the active immunization of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis caused by poliovirus Type 2. The vaccine contains purified and inactivated poliovirus type 2 that were...
Approved
Investigational
Matched Description: … Poliovirus type 2 antigen is a suspension of poliovirus Type 2 (MEF-1) used in the active immunization ... of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis caused ... vaccine contains purified and inactivated poliovirus type 2 that were grown from a continuous line of …
Matched Mixtures name: … VeroPol Injektionslösung in einer Fertigspritze ... -POLIO SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE ... Repevax Injektionssuspension in einer Fertigspritze …

Poliovirus type 3 antigen (formaldehyde inactivated)

Poliovirus type 3 antigen is a suspension of poliovirus Type 3 (Saukett) used in the active immunization of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis caused by poliovirus Type 3. The vaccine contains purified and inactivated poliovirus type 3 that were...
Approved
Investigational
Matched Description: … Poliovirus type 3 antigen is a suspension of poliovirus Type 3 (Saukett) used in the active immunization ... of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis caused ... vaccine contains purified and inactivated poliovirus type 3 that were grown from a continuous line of …
Matched Mixtures name: … VeroPol Injektionslösung in einer Fertigspritze ... -POLIO SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE ... Repevax Injektionssuspension in einer Fertigspritze …

Inositol

Inositol is a collection of nine different stereoisomers but the name is usually used to describe only the most common type of inositol, myo-inositol. Myo-inositol is the cis-1,2,3,5-trans-4,6-cyclohexanehexol and it is prepared from an aqueous extract of corn kernels by precipitation and hydrolysis of crude phytate. These molecules have structural...
Approved
Investigational
Withdrawn
Matched Description: … [L1113] By the FDA, inositol is considered in the list of specific substances affirmed as generally recognized ... the body, a deficiency in this molecule does not translate into disease conditions. ... the most common type of inositol, myo-inositol. …
Matched Mixtures name: … Mega 13 Multivitamin Formula ... Harvest Of Values All B Complex Tab …

Procarbazine

An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
Approved
Investigational
Matched Description: … (the MOPP protocol) in the treatment of Hodgkin's disease. ... An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Naldemedine

Naldemedine is an opioid receptor antagonist [FDA Label]. It is a modified form of DB00704 to which a side chain has been added to increase molecular weight and polar surface area resulting in restricted transport across the blood brain barrier. Naldemedine was approved in 2017 in both the US and...
Approved
Investigational
Matched Description: … Naldemedine was approved in 2017 in both the US and Japan for the treatment of Opioid-induced Constipation ... It is a modified form of [DB00704] to which a side chain has been added to increase molecular weight ... and polar surface area resulting in restricted transport across the blood brain barrier. …

Abemaciclib

Abemaciclib is an antitumor agent and dual inhibitor of cyclin-dependent kinases 4 (CDK4) and 6 (CDK6) that are involved in the cell cycle and promotion of cancer cell growth in case of unregulated activity. On September 28, 2017, FDA granted approval of abemaciclib treatment under the market name Verzenio for...
Approved
Investigational
Matched Description: … ) that are involved in the cell cycle and promotion of cancer cell growth in case of unregulated activity ... of cancer, or in combination with [DB00947]. ... Abemaciclib has been used in trials studying the treatment of melanoma, lymphoma, neoplasm, solid tumor …
Matched Salts cas: … 1231930-82-7 …

Conestat alfa

C1 Esterase Inhibitor (Recombinant) is a recombinant analogue of endogenous complement component-1 esterase inhibitor (rhC1INH), purified from the milk of transgenic rabbits. The primary function of endogenous C1INH is to regulate the activation of the complement and contact system pathways. It does this through inhibition of several target proteases within...
Approved
Investigational
Matched Description: … Intravenous replacement of C1 esterase inhibitor results in reversal of acute symptoms of HAE. ... Down-stream effects of the lack of enzyme inhibition by C1 esterase inhibitor results in swelling due ... Additionally, C4 and C2 cleavage occurs resulting in auto-activation of the complement system. …
Matched Categories: … Drugs Used in Hereditary Angioedema …

Streptococcus pneumoniae type 15b capsular polysaccharide antigen

Streptococcus pneumoniae type 15b capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 15b of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Description: … vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 15b of …
Matched Mixtures name: … PNEUMOVAX 23 Injektionslösung in einer Fertigspritze ... PNEUMOVAX 23 Injektionslösung in einer Durchstechflasche …

Amiloxate

Amiloxate is an EMA-approved chemical UV-filter found in over-the-counter sunscreen products at concentrations up to 10%m . It is often referred to as isoamyl 4-methoxycinnamate or isoamyl p-methoxycinnamate. Amiloxate is a cinnamic acid derivative with an anti-inflammatory activity .
Approved
Matched Description: … Amiloxate is an EMA-approved chemical UV-filter found in over-the-counter sunscreen products at concentrations …
Matched Mixtures name: … The History of Whoo Jin Hae Yoon Sun …

Poliovirus type 1 antigen (formaldehyde inactivated)

Poliovirus type 1 antigen is a suspension of poliovirus Type 1 (Mahoney) used in the active immunization of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis caused by poliovirus Type 1. The vaccine contains purified and inactivated poliovirus type 1 that were...
Approved
Investigational
Matched Description: … Poliovirus type 1 antigen is a suspension of poliovirus Type 1 (Mahoney) used in the active immunization ... of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis caused ... vaccine contains purified and inactivated poliovirus type 1 that were grown from a continuous line of …
Matched Mixtures name: … VeroPol Injektionslösung in einer Fertigspritze ... -POLIO SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE ... Repevax Injektionssuspension in einer Fertigspritze …

Cisatracurium

Cisatracurium is a non-depolarising neuromuscular blocking agent of the benzylisoquinolinium class, available in its salt form, cisatracurium besylate.[A243416,A253592] Cisatracurium has an intermediate duration of action and is one of the most commonly used neuromuscular blocking agents in intensive care.[A253592,A253597]. Cisatracurium acts on cholinergic receptors, blocking neuromuscular transmission. This action is...
Approved
Investigational
Matched Description: … in its salt form, cisatracurium besylate. ... used neuromuscular blocking agents in intensive care. ... [A243416,A253592] Cisatracurium has an intermediate duration of action and is one of the most commonly …

Carbenicillin

Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function.
Approved
Investigational
Matched Synonyms: … N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)hept-6-yl)-2-phenylmalonamic acid ... (2S,5R,6R)-6-{[carboxy(phenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic …
Matched Iupac: … (2S,5R,6R)-6-(2-carboxy-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic …
Matched Categories: … combinations of penicillins …

Phylloquinone

Vitamin K1, also called phylloquinone or phytonadione, is a fat soluble vitamin.[L33319,L33345] Phylloquinone is a cofactor of the enzyme γ-carboxylase, which modifies and activates precursors to coagulation factors II, VII, IX, and X.[A234264,A234195,A234259] It is indicated in the treatment of coagulation disorders due to faulty formation of coagulation factors II,...
Approved
Investigational
Matched Description: … of coagulation factors II, VII, IX, and X caused by deficiency or interference in the activity of vitamin ... [A234264,A234195,A234259] It is indicated in the treatment of coagulation disorders due to faulty formation ... [L33319,L33345] Phylloquinone is a cofactor of the enzyme γ-carboxylase, which modifies and activates …

Brigatinib

Brigatinib, originally named AP26113, is a reversible dual inhibitor of anaplastic lymphoma kinase (ALK) and epidermal growth factor receptor (EGFR). It presents selectivity against the mutant forms of EGFR compared to the wild-type. It also exhibits selectivity against 9 different Crizotinib-resistant mutants of the EML4-ALK fusion gene, which is a...
Approved
Investigational
Matched Description: … fusion gene, which is a pivotal player in the transformation of susceptible lung parenchyma. ... It presents selectivity against the mutant forms of EGFR compared to the wild-type. ... Brigatinib, originally named AP26113, is a reversible dual inhibitor of anaplastic lymphoma kinase (ALK …
Matched Mixtures name: … ALUNBRİG 90 MG VE 180 MG FİLM KAPLI TABLET TEDAVİYE BAŞLANGIÇ PAKETİ, 7 ADET 90 MG VE 21 ADET 180 MG ... ALUNBRİG 90 MG VE 180 MG FİLM KAPLI TABLET TEDAVİYE BAŞLANGIÇ PAKETİ, 7 ADET 90 MG VE 21 ADET 180 MG ... ALUNBRİG 90 MG VE 180 MG FİLM KAPLI TABLET TEDAVİYE BAŞLANGIÇ PAKETİ, 7 ADET 90 MG VE 23 ADET 180 MG …
Matched Products: … ALUNBRİG 90 MG FİLM KAPLI TABLET, 7 ADET …

Glucagon

Glucagon is a 29 amino acid hormone used as a diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and to treat severe hypoglycemia.[L7634,L7637,L7640,L7643,L8519] Glucagon raises blood sugar through activation of hepatic glucagon receptors, stimulating glycogenolysis and the release of glucose.[L7640,L7643] Glucagon was granted FDA...
Approved
Matched Description: … Glucagon is a 29 amino acid hormone used as a diagnostic aid in radiologic exams to temporarily inhibit ... , stimulating glycogenolysis and the release of glucose. ... the movement of the gastrointestinal tract and to treat severe hypoglycemia. …

Becaplermin

Becaplermin is produced by recombinant DNA technology by insertion of the gene for the B chain of platelet derived growth factor (PDGF) into the yeast, Saccharomyces cerevisiae. Becaplermin has a molecular weight of approximately 25 KD and is a homodimer composed of two identical polypeptide chains that are bound together...
Approved
Investigational
Matched Description: … Becaplermin is produced by recombinant DNA technology by insertion of the gene for the B chain of platelet ... Becaplermin has a molecular weight of approximately 25 KD and is a homodimer composed of two identical …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers …

Oritavancin

Oritavancin is a glycopeptide antibiotic used for the treatment of skin infections. It was developed by The Medicines Company (acquired by Novartis). Oritavancin was initially approved by the FDA in 2014 and formulated to combat susceptible gram-positive bacteria that cause skin and skin structure infections. It boasts the option of...
Approved
Investigational
Matched Description: … [A39384,A193482,L8492] On March 12, 2021 the FDA approved Kimyrsa, a complete course of therapy in ... of [vancomycin] therapy. ... [L12858] Oritavancin was initially approved by the FDA in 2014 and formulated to combat susceptible gram-positive …

Clobazam

Clobazam belongs to the 1,5-benzodiazepine class of drugs and is marketed under different names, Onfi, Frisium, Urbanyl, and others. . Clobazam was first synthesized in 1966 and first published in 1969, following the incidental synthesis and discovery of the first benzodiazepine chlordiazepoxide in the 1950s. Unlike older 1,4-benzodiazepines, clobazam has...
Approved
Illicit
Matched Synonyms: … 7-Chloro-1-methyl-5-phenyl-1,5-dihydro-benzo[b][1,4]diazepine-2,4-dione …
Matched Iupac: … 7-chloro-1-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine-2,4-dione …
Matched Description: … and discovery of the first benzodiazepine chlordiazepoxide in the 1950s. ... [A256963,A256868] This is likely because of clobazam's higher affinity to the α2 subunit of ... Clobazam was first synthesized in 1966 and first published in 1969, following the incidental synthesis …

Chloroquine

Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. Chloroquine and its derivative hydroxychloroquine have since been repurposed for the treatment of a...
Approved
Investigational
Vet approved
Matched Synonyms: … N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine …
Matched Iupac: … 7-chloro-N-[5-(diethylamino)pentan-2-yl]quinolin-4-amine …
Matched Description: … Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria ... [A192432] **The FDA emergency use authorization for [hydroxychloroquine] and chloroquine in the treatment ... [A191655] It was the drug of choice to treat malaria until the development of newer antimalarials such …

Technetium Tc-99m nofetumomab merpentan

Technetium Tc-99m nofetumomab merpentan (Tc-99m nm) consists of a Fab fragment of an IgG2b of the pancarcinoma murine antibody NR-LU-10. The NR-LU-10 antibody is directed against a 40 kDa glycoprotein antigen expressed in a variety of cancers and some normal tissues.[FDA label] Tc-99m nm was developed by Boehringer Ingelheim Pharma...
Approved
Withdrawn
Matched Description: … It was after discontinued on August 13, 2013, but in the 2018 FDA submission list, it can be found as ... Technetium Tc-99m nofetumomab merpentan (Tc-99m nm) consists of a Fab fragment of an IgG2b of the pancarcinoma ... [A32115] The NR-LU-10 antibody is directed against a 40 kDa glycoprotein antigen expressed in a variety …

Tyropanoic acid

Tyropanoic acid is a radiocontrast agent used in cholecystography, the X-ray diagnosis of gallstones under the trade names include Bilopaque, Lumopaque, Tyropaque, and Bilopac. The molecule contains three heavy iodine atoms which obstruct X-rays in the same way as the calcium in bones, which results in a visible image .
Approved
Matched Description: … Tyropanoic acid is a radiocontrast agent used in cholecystography, the X-ray diagnosis of gallstones ... The molecule contains three heavy iodine atoms which obstruct X-rays in the same way as the calcium in ... bones, which results in a visible image [L1608]. …
Matched Categories: … Diagnostic Uses of Chemicals ... Compounds used in a research, industrial, or household setting …

Emtricitabine

Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) indicated for the treatment of HIV infection in adults or combined with tenofovir alafenamide for the prevention of HIV-1 infection in high risk adolescents and adults. Emtricitabine is a cytidine analogue. The drug works by inhibiting HIV reverse transcriptase, preventing transcription of...
Approved
Investigational
Matched Description: … infection in adults[L9019] or combined with [tenofovir alafenamide] for the prevention of HIV-1 infection ... in high risk adolescents and adults. ... Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) indicated for the treatment of HIV …
Matched Categories: … Antivirals used in combination for the treatment of HIV infections …
Displaying drugs 251 - 275 of 10683 in total