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Displaying drugs 251 - 275 of 11875 in total
Aminocaproic acid
An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
Approved
Investigational
Matched Mixtures name: … NAVI Black and C-Clinic …
Exagamglogene autotemcel
Sickle cell disease (SCD) is a genetic disorder characterized by the production of abnormal sickle-shaped red blood cells (called hemoglobin S, HbS) that initiate a pathophysiology resulting in severe pain, progressive multi-organ damage, and premature death. Treatment options for SCD are largely focused on preventing the production and circulation of...
Approved
Investigational
Matched Description: … in HbS. ... sickle-shaped red blood cells (called hemoglobin S, HbS) that initiate a pathophysiology resulting in ... [L49231] It is the first CRISPR-based gene editing therapy to be approved in the United States. …
Influenza B virus B/Phuket/3073/2013 live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …
Influenza B virus B/Brisbane/60/2008 live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …
Turoctocog alfa pegol
Turoctocog alfa pegol is a pegylated version of turoctocog alfa. Novo Nordisk's brand name Esperoct (turoctocog alfa pegol, N8-GP) was approved by the US FDA on February 19, 2019.
Fundamentally, the N8-GP moiety is identical to turoctocog alfa, a recombinant human clotting factor VIII (rFVIII) with a truncated B-domain made...
Approved
Matched Description: … acid 720, and a monoclonal antibody binding C-terminal to this position is used in the purification ... During secretion, some rFVIII molecules are cleaved at the C-terminal of the heavy chain (HC) at amino ... B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus …
Influenza B virus B/Austria/1359417/2021 live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in …
Nintedanib
Nintedanib is a small molecule kinase inhibitor used in the treatment of pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and non-small cell lung cancer (NSCLC).[L8453,L8459] It was first approved for use in the United States in 2014. Within the spectrum of idiopathic pulmonary fibrosis treatment options, nintedanib is currently one...
Approved
Matched Description: … [L8453,L8459] It was first approved for use in the United States in 2014. ... Nintedanib is a small molecule kinase inhibitor used in the treatment of pulmonary fibrosis, systemic ... [A185237] As a chemotherapeutic agent for NSCLC, nintedanib, in combination with [Docetaxel], is reserved …
Becaplermin
Becaplermin is produced by recombinant DNA technology by insertion of the gene for the B chain of platelet derived growth factor (PDGF) into the yeast, Saccharomyces cerevisiae. Becaplermin has a molecular weight of approximately 25 KD and is a homodimer composed of two identical polypeptide chains that are bound together...
Approved
Investigational
Matched Categories: … Proto-Oncogene Proteins c-sis …
Tazobactam
Tazobactam is an antibiotic of the beta-lactamase inhibitor class that prevents the breakdown of other antibiotics by beta-lactamase enzyme producing organisms. It is combined with Piperacillin and Ceftolozane for the treatment of a variety of bacterial infections.
Piperacillin-tazobactam was initially approved by the FDA in 1994, and ceftolozane-tazobactam was approved...
Approved
Matched Description: … by the FDA in 2014[FDA label], providing wider antibacterial coverage for gram-negative infections. ... In June 2019, ceftolozane-tazobactam was approved by the FDA for treating hospital-acquired bacterial ... ventilator-associated bacterial pneumonia, which are significant causes of morbidity and mortality in …
Matched Mixtures name: … Zosyn in Galaxy Containers ... Zosyn in Galaxy Containers ... Zosyn in Galaxy Containers …
Matched Mixtures name: … Zosyn in Galaxy Containers ... Zosyn in Galaxy Containers ... Zosyn in Galaxy Containers …
Esculin
Esculin is found in barley. Vitamin C2 is generally considered a bioflavanoid, related to vitamin P esculin is a glucoside that naturally occurs in the horse chestnut (Aesculus hippocastanum), California Buckeye (Aesculus californica) and in daphnin (the dark green resin of Daphne mezereum). Esculin belongs to the family of Glycosyl...
Approved
Matched Description: … group via a C-, S-,N-,O-, or Se- glycosidic bond. ... Esculin is found in barley. ... generally considered a bioflavanoid, related to vitamin P esculin is a glucoside that naturally occurs in …
Theobroma cacao whole
Theobroma cacao, whole, allergenic extract is used in allergenic testing.
Approved
Matched Description: … Theobroma cacao, whole, allergenic extract is used in allergenic testing. …
Fluconazole
Fluconazole, commonly known as Diflucan, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. It was initially approved by the FDA in 1990. This drug is an azole antifungal, in the same drug family as ketoconazole and itraconazole. Fluconazole...
Approved
Investigational
Matched Description: … It was initially approved by the FDA in 1990. ... This drug is an _azole_ antifungal, in the same drug family as [ketoconazole] and [itraconazole]. ... Diflucan_, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in …
Matched Products: … Fluconazole in Dextrose ... Fluconazole in Sodium Chloride ... Fluconazole In Sodium Chloride Injection USP …
Matched Products: … Fluconazole in Dextrose ... Fluconazole in Sodium Chloride ... Fluconazole In Sodium Chloride Injection USP …
Salmeterol
Salmeterol is a long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and chronic obstructive pulmonary disease COPD.[L11545,L11548,L11551,L11554,L11557] It has a longer duration of action than the short-acting beta-2 adrenergic receptor agonist, salbutamol. Salmeterol was first described in the literature in 1988. Salmeterol's structure...
Approved
Matched Description: … [A190459] Salmeterol was first described in the literature in 1988. …
Matched Mixtures name: … SEROHALE 250 SYNCHROBREATHE SB ... SEROHALE 125 SYNCHROBREATHE SB …
Matched Mixtures name: … SEROHALE 250 SYNCHROBREATHE SB ... SEROHALE 125 SYNCHROBREATHE SB …
Hydroxocobalamin
Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B 12 that has been used therapeutically to treat vitamin B 12 deficiency. It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia.
Approved
Matched Description: … It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia. …
Matched Mixtures name: … TRIBEDOCE C/L …
Matched Mixtures name: … TRIBEDOCE C/L …
Cilazapril
Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure. It belongs to the angiotensin-converting enzyme inhibitors (ACE inhibitors) class of drugs. It is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat. It is branded as Inhibace in Canada and...
Approved
Matched Description: … It is branded as Inhibace in Canada and other countries, Vascace and Dynorm in a number of European countries ... None of these varieties are available in the United States. ... Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure. …
Pentoxyverine
Pentoxyverine, also referred to as carbetapentane, is a non-opioid central acting antitussive with antimuscarinic, anticonvulsant , and local anesthetic properties. It is an active ingredient in over-the-counter cough suppressants in combination with guaifenesin and H1-receptor antagonists . Pentoxyverine acts on sigma-1 receptors, as well as kappa and mu-opioid receptors.
The...
Approved
Investigational
Withdrawn
Matched Description: … It is an active ingredient in over-the-counter cough suppressants in combination with guaifenesin and …
Matched Mixtures name: … C-Tanna 12D Suspension …
Matched Mixtures name: … C-Tanna 12D Suspension …
Caffeine
Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness. Caffeine is similar in chemical structure to Theophylline and Theobromine.[A187691,L9851] It can be sourced from coffee beans, but also occurs naturally in...
Approved
Matched Description: … [A187694] Caffeine is beneficial in preventing and treating apnea and bronchopulmonary dysplasia in newborns ... This correlates to about 1 in 10 births. ... Caffeine is similar in chemical structure to [Theophylline] and [Theobromine]. …
Matched Mixtures name: … Acetaminophen 325 C & C ... . & C. 8mg ... Trianal C½ …
Matched Mixtures name: … Acetaminophen 325 C & C ... . & C. 8mg ... Trianal C½ …
Triclocarban
Triclocarban, with the chemical formula C13H9Cl3N2O is an antibacterial agent that is particularly effective against Gram-positive bacteria such as Staphylococcus aureus. It is a bacteriostatic compound that has been found in antibacterial soaps and other personal care products. In 2017, the US FDA prohibited the marketing of over-the-counter (OTC) consumer...
Approved
Matched Description: … In 2017, the US FDA prohibited the marketing of over-the-counter (OTC) consumer antiseptic wash products ... It is a bacteriostatic compound that has been found in antibacterial soaps and other personal care products …
Nabilone
Nabilone (marketed as Cesamet) is a synthetic form of delta-9-tetrahydrocannabinol (Δ⁹-THC), the primary psychoactive component of cannabis (marijuana). Although structurally distinct from THC, nabilone mimics THC's structure and pharmacological activity through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid-2 (CB2R) receptors, however it is considered to be twice as...
Approved
Investigational
Matched Iupac: … (6aR,10aR)-1-hydroxy-6,6-dimethyl-3-(2-methyloctan-2-yl)-6H,6aH,7H,8H,9H,10H,10aH-benzo[c]isochromen- …
Matched Description: … Though it was approved by the FDA in 1985, the drug only began marketing in the United States in 2006 ... It is also approved for use in treatment of anorexia and weight loss in patients with AIDS. ... CB1 receptors are found in both the central and peripheral nervous system, and are most abundant in the …
Matched Description: … Though it was approved by the FDA in 1985, the drug only began marketing in the United States in 2006 ... It is also approved for use in treatment of anorexia and weight loss in patients with AIDS. ... CB1 receptors are found in both the central and peripheral nervous system, and are most abundant in the …
Rimegepant
Rimegepant is an oral antagonist of the CGRP receptor developed by Biohaven Pharmaceuticals. It received FDA approval on February 27, 2020 for the acute treatment migraine headache, and was subsequently approved by the European Commission in April 2022 for both the treatment and prevention of migraines. While several parenteral antagonists...
Approved
Investigational
Matched Description: … acute treatment migraine headache,[L11974] and was subsequently approved by the European Commission in ... only CGRP antagonists that possessed oral bioavailability[A189207] until the approval of [atogepant] in ... abortive treatment with "triptans", such as [sumatriptan], but these medications are contraindicated in …
Ceftobiprole
Ceftobiprole is a fifth-generation semisynthetic cephalosporin antibacterial which is available commercially as the prodrug ceftobiprole medocaril. Ceftobiprole is a broad-spectrum agent with demonstrated activity against both Gram-positive and Gram-negative bacteria, including antibiotic-resistant strains of Staphylcoccus aureus (methicillin-resistant Staphylococcus aureus; MRSA).
The EMA's Committee for Medicinal Products for Human Use (CHMP)...
Approved
Investigational
Matched Description: … [L50467] It received its first approval in Canada in October 2017 for use in certain patients with bacterial ... due to data quality issues in pivotal clinical studies. ... skin and skin structure infections and bacteremia in April 2024. …
Potassium bicarbonate
Potassium bicarbonate is a white, crystalline, slightly alkaline and salty substance. It is produced by the passage of carbon dioxide through an aqueous potassium carbonate solution. It is used in medicine as an antacid. It is registered in the FDA under the section of suitable, safe and effective ingredients for...
Approved
Matched Description: … It is used in medicine as an antacid. ... [T141] It is registered in the FDA under the section of suitable, safe and effective ingredients for …
Matched Mixtures name: … Multi-min Electro C Pow Plus B2 ... Buffered Vitamin C Pwr W Cal-mag-potassium …
Matched Mixtures name: … Multi-min Electro C Pow Plus B2 ... Buffered Vitamin C Pwr W Cal-mag-potassium …
Cefditoren
Cefditoren is an oral third-generation cephalosporin. It is commonly marketed under the trade name Spectracef by Cornerstone BioPharma.
Approved
Investigational
Displaying drugs 251 - 275 of 11875 in total