Displaying drugs 2801 - 2825 of 3434 in total
Mersalyl
Mersalyl is the sodium salt form of mersalyl acid, a mercurial diuretic. It is an outdated drug, and its approval has been discontinued by the FDA. Mersalyl acid is currently replaced by less toxic non-mercury containing diuretics [L1575, L1577]. The sodium salt of a mercury-containing derivative of salicylamide, was formerly...
Experimental
Matched Synonyms: … Acidum mersalylicum …
Matched Iupac: … 2-(2-{[3-(hydroxymercurio)-2-methoxypropyl]carbamoyl}phenoxy)acetic acid …
Matched Description: … It is an outdated drug, and its approval has been discontinued by the FDA. ... Mersalyl is the sodium salt form of mersalyl acid, a mercurial diuretic. ... Mersalyl acid is currently replaced by less toxic non-mercury containing diuretics [L1575, L1577]. …
Matched Iupac: … 2-(2-{[3-(hydroxymercurio)-2-methoxypropyl]carbamoyl}phenoxy)acetic acid …
Matched Description: … It is an outdated drug, and its approval has been discontinued by the FDA. ... Mersalyl is the sodium salt form of mersalyl acid, a mercurial diuretic. ... Mersalyl acid is currently replaced by less toxic non-mercury containing diuretics [L1575, L1577]. …
Dornase alfa
Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. It is produced in genetically modified Chinese hamster ovary (CHO) cells using recombinant DNA technology. The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and...
Approved
Matched Synonyms: … Dornase alpha …
Matched Description: … Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and 5´-phosphooligonucleotide end products ... Enzymatic breakdown of this extracellular DNA appears to reduce sputum viscosity and viscoelasticity. ... The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Enzymes and Coenzymes …
Matched Description: … Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and 5´-phosphooligonucleotide end products ... Enzymatic breakdown of this extracellular DNA appears to reduce sputum viscosity and viscoelasticity. ... The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Enzymes and Coenzymes …
MMDA
MMDA, or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant and psychedelic properties. It also acts as an entheogen and an entactogen. MMDA bears resemblance to the psychopharmacologically active essential oils elemicin and myristicin found in nutmeg. The effects of MMDA includes feelings of euphoria and warmth,...
Experimental
Illicit
Matched Synonyms: … 3-Methoxy-alpha-methyl-4,5-methylenedioxyphenethylamine …
Matched Description: … It also acts as an entheogen and an entactogen. ... or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant and ... MMDA bears resemblance to the psychopharmacologically active essential oils elemicin and myristicin found …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Description: … It also acts as an entheogen and an entactogen. ... or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant and ... MMDA bears resemblance to the psychopharmacologically active essential oils elemicin and myristicin found …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Cobicistat
Cobicistat, marketed under the name Tybost (formerly GS-9350), indicated for treating infection with human immunodeficiency virus (HIV). Although it does not have any anti-HIV activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and therefore increases the systemic exposure of coadministered agents that are metabolized...
Approved
Matched Synonyms: … thiazol-4-yl)methyl](methyl)carbamoyl}amino)-4-(morpholin-4-yl)butanoyl]amino}-1,6-diphenylhexan-2-yl]carbamate …
Matched Iupac: … -yl)-1,3-thiazol-4-yl]methyl})carbamoyl]amino}-4-(morpholin-4-yl)butanamido]-1,6-diphenylhexan-2-yl]carbamate …
Matched Description: … activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and ... exposure of anti-retrovirals (ARVs) without increasing dosage allows for better treatment outcomes and …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... darunavir and cobicistat ... atazanavir and cobicistat ... Metabolic Side Effects of Drugs and Substances …
Matched Iupac: … -yl)-1,3-thiazol-4-yl]methyl})carbamoyl]amino}-4-(morpholin-4-yl)butanamido]-1,6-diphenylhexan-2-yl]carbamate …
Matched Description: … activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and ... exposure of anti-retrovirals (ARVs) without increasing dosage allows for better treatment outcomes and …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... darunavir and cobicistat ... atazanavir and cobicistat ... Metabolic Side Effects of Drugs and Substances …
8-oxo-dGMP
Experimental
Matched Synonyms: … 2'-deoxy-7,8-dihydro-8-oxo-5'-guanylic acid …
Matched Iupac: … ,3S,5R)-5-(6,8-dihydroxy-2-imino-3,9-dihydro-2H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy}phosphonic acid …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … ,3S,5R)-5-(6,8-dihydroxy-2-imino-3,9-dihydro-2H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy}phosphonic acid …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Clesrovimab
Clesrovimab is under investigation in clinical trial NCT04938830 (Clesrovimab (MK-1654) in Infants and Children at Increased Risk for Severe Respiratory Syncytial Virus (RSV) Disease (MK-1654-007)).
Investigational
Matched Synonyms: … Immunoglobulin g1 (262-tyrosine,264-threonine,266-glutamic acid), anti-(human respiratory syncytial virus …
Matched Description: … Clesrovimab is under investigation in clinical trial NCT04938830 (Clesrovimab (MK-1654) in Infants and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Clesrovimab is under investigation in clinical trial NCT04938830 (Clesrovimab (MK-1654) in Infants and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Nadofaragene firadenovec
Nadofaragene firadenovec (nadofaragene firadenovec-vncg) is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human interferon alfa-2b (IFNα2b). It was approved by the FDA on December 2022 for the treatment of high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS) with or without...
Approved
Investigational
Matched Synonyms: … alpha-2b) gene under the control of the cytomegalovirus (cmv) immediate-early enhancer/promoter ... Replication-deficient adenovirus type 5 (ad5) vector encoding the human interferon alpha 2 (ifna2, interferon …
Matched Description: … [L44381,L44431] BCG-unresponsive NMIBC has a high recurrence and is notably difficult to treat. ... firadenovec is formulated with an excipient (Syn-3) that facilitates gene transfer across the urothelium and …
Matched Categories: … Cellular and Gene Therapy ... Antineoplastic and Immunomodulating Agents ... Antineoplastic cell and gene therapy …
Matched Description: … [L44381,L44431] BCG-unresponsive NMIBC has a high recurrence and is notably difficult to treat. ... firadenovec is formulated with an excipient (Syn-3) that facilitates gene transfer across the urothelium and …
Matched Categories: … Cellular and Gene Therapy ... Antineoplastic and Immunomodulating Agents ... Antineoplastic cell and gene therapy …
North-methanocarbathymidine
Investigational
Matched Synonyms: … .,2.alpha.,4.beta.,5.alpha ... 2,4(1h,3h)-pyrimidinedione, 1-(4-hydroxy-5-(hydroxymethyl)bicyclo(3.1.0)hex-2-yl)-5-methyl-, (1s-(1.alpha …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
(3,4,8b-Trimethyl-3-oxido-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-3-ium-7-yl) N-(2-ethylphenyl)carbamate
Experimental
Matched Name: … (3,4,8b-Trimethyl-3-oxido-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-3-ium-7-yl) N-(2-ethylphenyl)carbamate …
METHYL(2-ACETOXY-2-(2-CARBOXY-4-AMINO-PHENYL))ACETATE
Experimental
Matched Name: … METHYL(2-ACETOXY-2-(2-CARBOXY-4-AMINO-PHENYL))ACETATE …
Matched Iupac: … 2-[(1R)-1-(acetyloxy)-2-methoxy-2-oxoethyl]-5-aminobenzoic acid …
Matched Iupac: … 2-[(1R)-1-(acetyloxy)-2-methoxy-2-oxoethyl]-5-aminobenzoic acid …
Cefapirin
Cefapirin (INN, also spelled cephapirin), commonly marketed under the trade name Cefadyl, is a first-generation cephalosporin antibiotic that is available in injectable formulations. Production for use in humans has been discontinued in the United States. Cefapirin is partly plasma-bound and is effective against gram-negative and gram-positive organisms.
Approved
Vet approved
Matched Synonyms: … acetoxymethyl)-8-oxo-7-{[(pyridin-4-ylsulfanyl)acetyl]amino}-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … methyl]-8-oxo-7-[2-(pyridin-4-ylsulfanyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … Cefapirin is partly plasma-bound and is effective against gram-negative and gram-positive organisms. …
Matched Categories: … Thiazines …
Matched Iupac: … methyl]-8-oxo-7-[2-(pyridin-4-ylsulfanyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … Cefapirin is partly plasma-bound and is effective against gram-negative and gram-positive organisms. …
Matched Categories: … Thiazines …
TMP
Experimental
Matched Synonyms: … 5-methyl-5'-uridylic acid …
Matched Iupac: … -3,4-dihydroxy-5-(4-hydroxy-5-methyl-2-oxo-1,2-dihydropyrimidin-1-yl)oxolan-2-yl]methoxy}phosphonic acid …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … -3,4-dihydroxy-5-(4-hydroxy-5-methyl-2-oxo-1,2-dihydropyrimidin-1-yl)oxolan-2-yl]methoxy}phosphonic acid …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Nitroglycerin
Nitroglycerin, also known as glyceryl trinitrate, is an organic nitrate and a vasodilating agent that was first discovered in 1847. Originally used to dynamite, its antianginal effects were identified in the late 1860s after it produced headaches in factory workers while workers with angina pectoris or heart failure experienced relief...
Approved
Investigational
Matched Synonyms: … Glycerol, nitric acid triester …
Matched Description: … [A180166,A180172] Its use as a treatment for angina dates back to 1879 and is still used to treat and ... Nitroglycerin, also known as glyceryl trinitrate,[A180169] is an organic nitrate and a vasodilating agent ... [A249970] Nitroglycerin causes vasodilation in both arteries and veins. …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Nitrates and Nitrites …
Matched Description: … [A180166,A180172] Its use as a treatment for angina dates back to 1879 and is still used to treat and ... Nitroglycerin, also known as glyceryl trinitrate,[A180169] is an organic nitrate and a vasodilating agent ... [A249970] Nitroglycerin causes vasodilation in both arteries and veins. …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Nitrates and Nitrites …
CL-315555
CL-315555 is the C isomer of Verteporfin.
Approved
Matched Synonyms: … 23h,25h-benzo(b)porphine-9,13-dipropanoic acid, 18-ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19 …
Matched Iupac: … ^{8,11}.1^{13,16}.0^{19,24}]octacosa-1,3,5,7,9,11(27),12,14,16,18(25),19,21-dodecaen-9-yl]propanoic acid …
Matched Iupac: … ^{8,11}.1^{13,16}.0^{19,24}]octacosa-1,3,5,7,9,11(27),12,14,16,18(25),19,21-dodecaen-9-yl]propanoic acid …
Ticarcillin
An antibiotic derived from penicillin similar to carbenicillin in action.
Approved
Investigational
Vet approved
Matched Synonyms: … carboxy-2-thiophen-3-ylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … carboxy-2-(thiophen-3-yl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … carboxy-2-(thiophen-3-yl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Cinpanemab
Cinpanemab is under investigation in clinical trial NCT03318523 (Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of BIIB054 in Participants With Parkinson's Disease).
Investigational
Matched Synonyms: … Immunoglobulin g1-lambda, anti-(homo sapiens snca (synuclein alpha, alpha-synuclein, park1, park4, parkinson ... Immunoglobulin g1, anti-(human .alpha. ... Immunoglobulin g1-lambda, anti-(homo sapiens alpha-synuclein)humanized monoclonal antibody.gamma.1 heavy …
Matched Description: … under investigation in clinical trial NCT03318523 (Evaluating the Efficacy, Safety, Pharmacokinetics, and …
Matched Description: … under investigation in clinical trial NCT03318523 (Evaluating the Efficacy, Safety, Pharmacokinetics, and …
L-Dilinoleoyllecithin
Experimental
Matched Synonyms: … DLPC ... DL-PC …
Matched Categories: … Phosphatidic Acids …
Matched Categories: … Phosphatidic Acids …
Limonene, (+/-)-
Limonene, (+/-)- is under investigation in clinical trial NCT05525260 (Limonene for Pulmonary Nodule Chemoprevention).
Investigational
Matched Synonyms: … Limonene, dl- …
Dienestrol
Dienestrol is a synthetic, non-steroidal estrogen. It is an estrogen receptor agonist. Estrogens work partly by increasing a normal clear discharge from the vagina and making the vulva and urethra healthy. Using or applying an estrogen relieves or lessens: dryness and soreness in the vagina, itching, redness, or soreness of...
Approved
Investigational
Matched Synonyms: … alpha-dienestrol diacetate …
Matched Description: … Estrogens work partly by increasing a normal clear discharge from the vagina and making the vulva and ... Using or applying an estrogen relieves or lessens: dryness and soreness in the vagina, itching, redness ... include a genital skin condition (vulvar atrophy), inflammation of the vagina (atrophic vaginitis), and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Matched Description: … Estrogens work partly by increasing a normal clear discharge from the vagina and making the vulva and ... Using or applying an estrogen relieves or lessens: dryness and soreness in the vagina, itching, redness ... include a genital skin condition (vulvar atrophy), inflammation of the vagina (atrophic vaginitis), and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Azidocillin
Azidocillin is a penicillin antibiotic similir to ampicillin.
Experimental
Matched Synonyms: … 2R)-2-azido-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … -[(2R)-2-azido-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … -[(2R)-2-azido-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Seclidemstat
Investigational
Matched Synonyms: … Benzoic acid, 3-((4-methyl-1-piperazinyl)sulfonyl)-, (2e)-2-(1-(5-chloro-2-hydroxyphenyl)ethylidene)hydrazide …
Avizakimab
Avizakimab is under investigation in clinical trial NCT03371251 (Study of BOS161721 in Systemic Lupus Erythematosus (SLE) Patients on a Background of Limited Standard of Care).
Investigational
Matched Synonyms: … Immunoglobulin g1 (251-tyrosine,253-threonine,255-glutamic acid), anti-(human interleukin 21) (human-mus …
O-(N-acetyl-alpha-D-galactosaminyl)-L-serine
Experimental
Matched Name: … O-(N-acetyl-alpha-D-galactosaminyl)-L-serine …
Matched Iupac: … 2S)-2-amino-3-{[(2S,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}propanoic acid …
Matched Iupac: … 2S)-2-amino-3-{[(2S,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}propanoic acid …
N-(R-Carboxy-Ethyl)-Alpha-(S)-(2-Phenylethyl)
Experimental
Matched Name: … N-(R-Carboxy-Ethyl)-Alpha-(S)-(2-Phenylethyl) …
Matched Iupac: … -[(1H-imidazol-2-yl)methyl]piperidin-4-yl}-1-(4-pentylphenyl)formamido)methyl]-[1,1'-biphenyl]-4-yl}acetate …
Matched Iupac: … -[(1H-imidazol-2-yl)methyl]piperidin-4-yl}-1-(4-pentylphenyl)formamido)methyl]-[1,1'-biphenyl]-4-yl}acetate …
Glycyl-L-alpha-amino-epsilon-pimelyl-D-alanine
Experimental
Matched Name: … Glycyl-L-alpha-amino-epsilon-pimelyl-D-alanine …
Matched Iupac: … (2S)-2-(2-aminoacetamido)-6-{[(1R)-1-carboxyethyl]carbamoyl}hexanoic acid …
Matched Iupac: … (2S)-2-(2-aminoacetamido)-6-{[(1R)-1-carboxyethyl]carbamoyl}hexanoic acid …
Displaying drugs 2801 - 2825 of 3434 in total