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Displaying drugs 2826 - 2850 of 3370 in total

Betahistine

Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss. It has a significant impact on both the physical and social functioning of affected individuals.[A220318,L16408] Betahistine is a histamine-like antivertigo drug used for treating symptoms associated with Ménière's disease. It is thought to...
Approved
Investigational
Matched Description: … Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing ... It has a significant impact on both the physical and social functioning of affected individuals. ... [A220318,L16408] Betahistine is a histamine-like antivertigo drug used for treating symptoms associated …
Matched Products: … Betahist Forte Tablets 16mg ... VASOSERC FORT 16 MG TABLET, 60 ADET ... ROTASTIN FORT 16 MG TABLET, 60 ADET …

Hydrocortisone succinate

Approved
Matched Iupac: … 3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethoxy}-4-oxobutanoic acid …
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SOLU-CORTEF FOR INJECTION 100 mg/vial ... Hydrocortisone Sodium Succinate for Injection ... HYDROCORTISONE SODIUM SUCCINATE FOR INJECTION B. P …

Trimethyllysine

Experimental
Matched Synonyms: … (S)-2-amino-6-(trimethylammonio)hexanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino …

Fidrisertib

Investigational
Matched Synonyms: … 1-piperazinecarboxylic acid, 4-(6-(5-(4-ethoxy-1-(1-methylethyl)-4-piperidinyl)-2-pyridinyl)pyrrolo(1,2 …

Sodium zirconium cyclosilicate

Sodium zirconium cyclosilicate is approved as the trade product Lokelma developed by AstraZeneca - an insoluble, non-absorbed sodium zirconium silicate, formulated as a powder for oral suspension that acts as a highly selective potassium removing agent. It is administered orally and is odorless, tasteless, and stable at room temperature. Approval...
Approved
Investigational
Matched Description: … [L2933] It is administered orally and is odorless, tasteless, and stable at room temperature. ... Approval of the medication is supported by data from three double-blind, placebo-controlled trials and ... two open-label trials which showed that the onset of action was approximately 1.0 hour and the median …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia ... Ion Exchange Resins ... Acids ... Acids, Noncarboxylic ... Gastric Acid Lowering Agents …
Matched Products: … LOKELMA POWDER FOR ORAL SUSPENSION 5G ... LOKELMA POWDER FOR ORAL SUSPENSION 10G ... Lokelma 5g Powder for Oral Suspension …

Tigecycline

Tigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil. It was developed in response to the growing prevalence of antibiotic resistance in bacteria such as Staphylococcus aureus. It was granted fast-track approval by the U.S. Food and Drug Administration (FDA) on June 17, 2005.
Approved
Matched Description: … Food and Drug Administration (FDA) on June 17, 2005. ... Tigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Tigaciv 50mg Lyophilized Powder for Concentrate for Solution for Infusion ... TIGECYCLINE SANDOZ POWDER FOR SOLUTION FOR INFUSION 50 MG PER VIAL ... TIGAR 50 (Tigecycline Powder for Solution for Infusion 50mg/Vial) …

Interferon beta-1a

Human interferon beta (166 residues), glycosylated, MW=22.5kD. It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta gene has been introduced. The amino acid sequence is identical to that of natural human interferon beta.
Approved
Investigational
Matched Description: … The amino acid sequence is identical to that of natural human interferon beta. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … Rebif 22mcg/0.5ml solution for injection ... Rebif 44mcg/0.5ml solution for injection ... Rebif Solution for Injection in Cartridge 22mcg/0.5ml …

Iltamiocel

Investigational
Matched Synonyms: … THE EXPANSION IS CONSISTENT WITH ROUTINE CELL CULTURE PRACTICES FOR ADHERENT CELLS. …

Pemetrexed

Pemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the brand name Alimta. It is indicated for use in combination with cisplatin for the treatment of patients with malignant pleural mesothelioma whose disease is either unresectable or who are otherwise not candidates for...
Approved
Investigational
Matched Iupac: … )-2-{[4-(2-{2-amino-4-oxo-1H,4H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}ethyl)phenyl]formamido}pentanedioic acid …
Matched Description: … Pemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the ... It is indicated for use in combination with cisplatin for the treatment of patients with malignant pleural ... mesothelioma whose disease is either unresectable or who are otherwise not candidates for curative surgery …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Dicarboxylic …
Matched Products: … Pemirex powder for concentrate for solution for infusion 500mg ... Pemirex powder for concentrate for solution for infusion 100mg ... EMETA 500mg Powder for Concentrate for Solution for Infusion …

Ixabepilone

Ixabepilone is an epothilone B analog developed by Bristol-Myers Squibb as a cancer drug. It was FDA approved on October 16, 2007, for the treatment of unresponsive aggressive metastatic or locally advanced breast cancer. Ixabepilone is administered through injection, and will be marketed under the trade name Ixempra. Ixabepilone is...
Approved
Investigational
Matched Description: … Ixabepilone is administered through injection, and will be marketed under the trade name Ixempra. ... It was FDA approved on October 16, 2007, for the treatment of unresponsive aggressive metastatic or locally …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … IXEMPRA FOR INJECTION 15 MG ... IXEMPRA (FOR INJECTION 15 MG) ... IXEMPRA FOR INJECTION 45 MG …

Decitabine

Myelodysplastic syndromes (MDS) are a heterogeneous group of hematopoietic neoplasms with variable underlying etiology and presentation, including neutropenia and thrombocytopenia. Further mutations leading to increased proliferation of cancerous cells can eventually lead to secondary acute myeloid leukemia, which has a poor prognosis.[A215082, A215092] Among treatment options, nucleoside analogues such as...
Approved
Investigational
Matched Description: … approved by the FDA for the treatment of MDS on February 5, 2006. ... presentation, including neutropenia and thrombocytopenia. ... and related downstream therapeutic benefits. …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Antineoplastic and Immunomodulating Agents ... Nucleic Acid Synthesis Inhibitors …
Matched Products: … DACOGEN (Decitabine) 50 mg Powder for Concentrate for Solution for Infusion ... Redtibin (Decitabine) Powder for Injection 50mg/vial …

Daunorubicin

A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of leukemia and other neoplasms.
Approved
Matched Description: … , used in treatment of leukemia and other neoplasms. ... A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... cytarabine and daunorubicin ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … DAUNOCIN FOR INJ ... DAUNOCIN FOR INJECTION 20 mg/vial ... DAUNOBLASTINA FOR INJECTION 20 mg/vial …

PPI-1040

Investigational
Matched Synonyms: … 4,7,10,13,16,19-docosahexaenoic acid, 2-((1z)-1-hexadecen-1-yloxy)-1-(((2-oxido-1,3,2-oxazaphospholidin …

Methoxsalen

A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA adducts in the presence of ultraviolet A irradiation.
Approved
Matched Synonyms: … 6-hydroxy-7-methoxy-5-benzofuranacrylic acid δ-lactone …
Matched Description: … It is a photoactive substance that forms DNA adducts in the presence of ultraviolet A irradiation. …
Matched Categories: … Indicators and Reagents ... Antipsoriatics for Systemic Use ... Antipsoriatics for Topical Use ... Psoralens for Topical Use ... Psoralens for Systemic Use …

Leflunomide

Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and pharmacologically very heterogeneous. Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999.
Approved
Investigational
Matched Synonyms: … 5-Methylisoxazole-4-carboxylic acid (4-trifluoromethyl)anilide …
Matched Description: … belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and ... Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Leflunomide and metabolite …

Glycyl-L-a-Aminopimelyl-E-(D-2-Aminoethyl)Phosphonate

Experimental
Matched Name: … Glycyl-L-a-Aminopimelyl-E-(D-2-Aminoethyl)Phosphonate …

Guselkumab

Guselkumab is a human immunoglobulin G1 lambda (IgG1λ) monoclonal antibody that selectively blocks interleukin-23. IL-23 is an inflammatory cytokine that activates the CD4+ T-helper (Th17) cell pathway to mediate the inflammatory cascade that induces psoriatic plaque formation . In clinical trials, guselkumab demonstrated improved skin clearance and symptomatic improvements in...
Approved
Investigational
Matched Description: … In clinical trials, guselkumab demonstrated improved skin clearance and symptomatic improvements in dermatological ... Developed by Janssen, the subcutenous injection form of guselkumab was approved in July 2017 under the ... market name Tremfya for the treatment of adult patients with moderate-to-severe plaque psoriasis. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Skin and Mucous Membrane Agents …
Matched Products: … TREMFYA 100MG/ML SOLUTION FOR INJECTION ... Tremfya One-Press 100mg/ml Solution for Injection ... TREMFYA SOLUTION FOR INJECTION IN PRE-FILLED PEN 100MG/ML …

Emicizumab

Emicizumab is a humanized recombinant monoclonal antibody that mimics the function of the coagulation Factor VIII and it has the capacity to bind simultaneously to activated Factor IX and Factor X. The ability of Emicizumab to bind to all these three different factors allows it to overcome immunogenicity and unstable...
Approved
Investigational
Matched Description: … Emicizumab was originated as an improved form of hBS23 and it was approved on November 16, 2017. ... Ltd. and co-developed with Roche and Genentech.[L1015] ... a humanized recombinant monoclonal antibody that mimics the function of the coagulation Factor VIII and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … HEMLIBRA 30MG/ML SOLUTION FOR INJECTION ... HEMLIBRA 150MG/ML SOLUTION FOR INJECTION ... HEMLIBRA SOLUTION FOR INJECTION 30MG/ML …

Insulin glulisine

Insulin glulisine is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … B3 is replaced by lysine and the lysine at position B29 is replaced by glutamic acid. ... a build-up of ketone acids in the blood and a syndrome called ketoacidosis, which is a life-threatening ... Insulin glulisine is a short-acting form of insulin used for the treatment of hyperglycemia caused by …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Insulins and Analogues for Injection, Fast-Acting ... Alimentary Tract and Metabolism ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … APIDRA 100 Units/ml Solution for Injection in vial ... APIDRA 100 U/ML- SOLUTION FOR INJECTION IN VIAL ... Apidra SoloStar 100 Units/ml Solution for injection in a pre-filled pen …

Plerixafor

Plerixafor is a small-molecule inhibitor of C-X-C chemokine receptor type 4 (CXCR4) that acts as a hematopoietic stem cell mobilizer.[A7117,L45678] It is used to stimulate the release of stem cells from the bone marrow into the blood in patients with non-Hodgkin's lymphoma (NHL) and multiple myeloma to stimulate their immune...
Approved
Investigational
Matched Description: … These stem cells are then collected and used in autologous stem cell transplantation to replace blood-forming ... of achieving the optimal CD34+ cell target for tandem transplantation in fewer apheresis procedures. ... Since CXCR4 and SDF-1α are involved in the trafficking and homing of CD34+ cells to the marrow compartment …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Mozobil 20 mg/ml solution for injection ... Mozobil Solution for Injection 20mg/ml ... PLERIXAFOR SEACROSS 20 MG/ML SOLUTION FOR INJECTION …

Ferric derisomaltose

Iron deficiency is an extremely common condition and is the most frequent cause of anemia worldwide. Iron deficiency results when iron intake, iron stores, and loss of iron from the body do not adequately support production of erythrocytes, also known as red blood cells. Though it is generally considered non...
Approved
Matched Description: … is associated with other forms of injectable iron. ... [A190528] Ferric derisomaltose is a form of iron used in the treatment of iron deficiency. ... [L11581,L11587] Clinical trials show that it is non-inferior to [iron sucrose], another form of iron …
Matched Products: … MONOFER® SOLUTION FOR INJECTION OR INFUSION 100 MG/ML ... Monofer 100 mg/ml solution for injection/infusion in vials ... Monofer 100mg/ml solution for injection/infusion in ampoules …

Atosiban

Atosiban is an inhibitor of the hormones oxytocin and vasopressin. It is used intravenously to halt premature labor. Although initial studies suggested it could be used as a nasal spray and hence would not require hospital admission, it is not used in that form. Atobisan was developed by the Swedish...
Approved
Investigational
Matched Description: … Atosiban is licensed in proprietary and generic forms for the delay of imminent pre-term birth in pregnant ... admission, it is not used in that form. ... Atosiban is an inhibitor of the hormones oxytocin and vasopressin. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … TRACTOCILE 7.5MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION ... TRACTOCILE (7.5 MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION) ... TRACTOCILE 7.5MG/ML,SOLUTION FOR INJECTION …

Atracurium besylate

A non-depolarizing neuromuscular blocking agent with short duration of action. Its lack of significant cardiovascular effects and its lack of dependence on good kidney function for elimination provide clinical advantage over alternate non-depolarizing neuromuscular blocking agents.
Approved
Matched Description: … Its lack of significant cardiovascular effects and its lack of dependence on good kidney function for …
Matched Products: … Atracurium - (for Single Dose ) ... Atracurium Kabi 10mg/ml Solution for Injection USP ... ATRACURIUM LABATEC IV SOLUTION FOR INJECTION 10MG/ML …

Galcanezumab

Galcanezumab is a humanized monoclonal antibody developed by Eli Lilly and Company against human calcitonin gene-related peptide (CGRP). Although several small-molecule CGRP receptor antagonists have been developed, humanized monoclonal antibodies like galcanezumab are specifically designed to selectively bind to CGRP entities with high potency. Given this target specificity, lack of...
Approved
Investigational
Matched Description: … [A33112] Galcanezumab was approved by the FDA in September 2018, and is indicated for the preventive ... promising safety and tolerability. ... Galcanezumab is a humanized monoclonal antibody developed by Eli Lilly and Company against human calcitonin …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … EMGALITY SOLUTION FOR INJECTION IN PRE-FILLED PEN 120 MG/ML ... Pontevia 120 mg solution for injection in pre-filled pen ... EMGALITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 100 MG/ML …

NBI-98782

Approved
Investigational
Matched Synonyms: … (2r,3r,11br)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2h-benzo(a)quinolizin-2-ol …
Displaying drugs 2826 - 2850 of 3370 in total