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Displaying drugs 2926 - 2950 of 3344 in total
Experimental
Matched Name: … 2-(2-{2-[(BIPHENYL-4-YLMETHYL)-AMINO]-3-MERCAPTO-PENTANOYLAMINO}-ACETYLAMINO)-3-METHYL-BUTYRIC ACID METHYL …
Experimental
Matched Name: … 8-BENZO[1,3]DIOXOL-,5-YLMETHYL-9-BUTYL-9H- …
Eculizumab is a monoclonal antibody that targets complement protein C5.[L6919,A2245] Binding to this protein prevents the activation of a complement terminal complex, which is used to treat a number of autoimmune conditions.[L6919,A2245,A2246] Eculizumab was granted FDA approval on 16 March 2007. In Q1 2023, the EMA's Committee for Medicinal Products...
Approved
Investigational
Matched Description: … [L6919] In Q1 2023, the EMA's Committee for Medicinal Products for Human Use (CHMP) adopted a positive ... opinion of two formulations of eculizumab indicated for the treatment of paroxysmal nocturnal hemoglobinuria …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Soliris Concentrate for Solution for Infusion 300mg/vial …
Doripenem is a broad-spectrum, carbapenem antibiotic marketed under the brand name Doribax by Janssen. Doripenem injection was approved by the FDA in 2007 to treat complicated urinary tract and intra-abdominal infections. In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin), it was found that...
Approved
Investigational
Matched Iupac: … ,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl]sulfanyl}-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
Matched Description: … to reiterate its safety and efficacy for its approved indications. ... Doripenem injection was approved by the FDA in 2007 to treat complicated urinary tract and intra-abdominal ... In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Powder for Injection 500mg ... DORIBAX 500 MG (Doripenem) for Injection …
Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and maintaining cell function.[A252235,A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in...
Approved
Investigational
Nutraceutical
Matched Synonyms: … Acidol
Matched Description: … The FDA and EMA have approved the product Cystadane (betaine anhydrous, oral solution) for the treatment ... occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and ... A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in plasma and
Matched Mixtures name: … Glutamic Acid Pepsin and Betaine Tablets ... Betaine HCl and Pepsin ... Rocky Mountain Multiple Vit and Min Mega Tab …
Matched Categories: … Amino Acids and Derivatives ... Alimentary Tract and Metabolism ... Acid Preparations …
Matched Products: … Betaine Anhydrous For Oral Solution ... Betaine Anhydrous for Oral Solution …
Obinutuzumab is a humanized monoclonal antibody used as a combination treatment with chlorambucil to treat patients with untreated chronic lymphocytic leukemia. It was approved by the FDA in November 2013 and is marketed under the brand name Gazyva. There is a black box warning of fatal Hepatitis B Virus (HBV)...
Approved
Investigational
Matched Description: … It was approved by the FDA in November 2013 and is marketed under the brand name Gazyva. ... There is a black box warning of fatal Hepatitis B Virus (HBV) reactivation and fatal Progressive Multifocal …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … GAZYVA 1000 MG/ 40 ML CONCENTRATE FOR SOLUTION FOR INFUSION ... GAZYVA CONCENTRATE FOR SOLUTION FOR INFUSION 1000MG/40ML …
Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1.[L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1....
Approved
Investigational
Matched Description: … It consists of 934 amino acids. ... [L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region ... variety of inflammatory conditions including rheumatoid arthritis (RA), ankylosing spondylitis (AS), and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Biologics for Rheumatoid Arthritis Treatment …
Matched Products: … ENBREL FOR INJECTION 25 mg/vial ... Enbrel Solution for Injection in a Pre-filled Pen 50mg ... Eucept 50 mg / mL Solution for Injection in Pre-filled Syringe …
Terlipressin is a synthetic analogue of vasopressin, which is an endogenous neurohormone that acts as a vasoconstrictor. It is a prodrug of lypressin, or lysine vasopressin. Compared to endogenous vasopressin, terlipressin has a longer half life and increased selectivity for the V1 receptor. As a potent vasopressor, terlipressin has been...
Approved
Investigational
Matched Description: … Compared to endogenous vasopressin, terlipressin has a longer half life and increased selectivity for ... [L43217] As a potent vasopressor, terlipressin has been investigated in various shock states and conditions ... [A2601, A2602, A2603, A2604, A2605] It was also studied in hepatorenal syndrome (HRS) and variceal bleeding …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Insulins ... Vasopressin and Analogues …
Matched Products: … GLYPRESSIN FOR INJECTION 1 mg/vial ... GLYPRESSIN 1mg/8.5ml solution for injection ... GLYPRESSIN solution for injection, 1 mg/8.5 ml …
Experimental
Matched Name: … [4-(4-Hydroxy-Benzyl)-2-(2-Hydroxy-1-Methyl-Ethyl)-5-Oxo-Imidazolidin-1-Yl]-Acetic Acid
Matched Iupac: … -1-amino-2-hydroxyethyl]-4-[(4-hydroxyphenyl)methylidene]-5-oxo-4,5-dihydro-1H-imidazol-1-yl]acetic acid
Experimental
Matched Name: … 3-(9-HYDROXY-1,3-DIOXO-4-PHENYL-2,3-DIHYDROPYRROLO[3,4-C]CARBAZOL-6(1H)-YL)PROPANOIC ACID
Matched Iupac: … 3-{9-hydroxy-1,3-dioxo-4-phenyl-1H,2H,3H,6H-pyrrolo[3,4-c]carbazol-6-yl}propanoic acid
Experimental
Matched Name: … DIMETHYLAMINO)PROP-1-ENYL]-4-FLUOROPHENYL}SULFONYL)AMINO]-5,6,7,8-TETRAHYDRONAPHTHALENE-1-CARBOXYLIC ACID
Matched Iupac: … dimethylamino)prop-1-en-1-yl]-4-fluorobenzenesulfonamido}-5,6,7,8-tetrahydronaphthalene-1-carboxylic acid
Experimental
Matched Name: … 1-{[1-(2-AMINO-3-PHENYL-PROPIONYL)-PYRROLIDINE-2-CARBONYL]-AMINO}-2-(3-CYANO-PHENYL)-ETHANEBORONIC ACID
Matched Iupac: … -{[(2S)-1-[(2R)-2-amino-3-phenylpropanoyl]pyrrolidin-2-yl]formamido}-2-(3-cyanophenyl)ethyl]boronic acid
Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and -resistant Staphylococcus aureus (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE).[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked...
Approved
Investigational
Matched Iupac: … carbamoyl}-3-[(2R)-3-carbamoyl-2-[(2S)-2-decanamido-3-(1H-indol-3-yl)propanamido]propanamido]propanoic acid
Matched Description: … and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked ring and the N-terminal ... with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and ... -resistant _Staphylococcus aureus_ (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE). …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … DAPTOCCORD 500 POWDER FOR SOLUTION FOR INJECTION OR INFUSION 500 MG/VIAL ... Daptomycin for Injection ... Daptomycin for Injection RF …
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is...
Approved
Matched Description: … Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic ... It is also found in plants and is used pharmacologically as a sympathomimetic. ... Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse …
Matched Categories: … Adrenergic and Dopaminergic Agents ... Alpha-and Beta-adrenergic Agonists ... Epinephrine and similars …
Matched Products: … N-EPI® 1mg/ml Concentrate for Solution for Infusion ... Noradrenaline Sintetica 1mg/ml Concentrate for Solution for Infusion ... NORADRENALINE AGUETTANT 1MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION …
A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2 (B2 CAS # 9060-10-0). It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. Bleomycin A2 is used as the representative structure for Bleomycin.
Approved
Investigational
Matched Description: … It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. ... of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and ... Bleomycin A2 is used as the representative structure for Bleomycin. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Bleomycin for Injection ... Bleomycin for Injection USP ... BLOICIN-S FOR INJECTION 15 UNITS …
Avibactam is a non-β-lactam β-lactamase inhibitor that is available in combination with ceftazidime (Avycaz). This combination was approved by the FDA on February 25, 2015 for the treatment of complicated intra-abdominal infections in combination with metronidazole, and the treatment of complicated urinary tract infections, including pyelonephritis caused by antibiotic resistant-pathogens,...
Approved
Matched Iupac: … [(2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl]oxidanesulfonic acid
Matched Description: … As there is limited clinical safety and efficacy data, Avycaz should be reserved for patients over 18 ... infections in combination with metronidazole, and the treatment of complicated urinary tract infections ... This combination was approved by the FDA on February 25, 2015 for the treatment of complicated intra-abdominal …
Matched Products: … ZAVICEFTA POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 2G/0.5G …
Trastuzumab deruxtecan is a HER2-directed antibody attached to a topoisomerase inhibitor that is approved for use in certain types of treatment-resistant HER2-positive cancers. It is classified as an antibody-drug conjugate. The cleavable peptide linker used to bind the antibody and drug in this product distinguishes it from other members of...
Approved
Investigational
Matched Description: … The cleavable peptide linker used to bind the antibody and drug in this product distinguishes it from ... A188988] Trastuzumab deruxtecan was developed by Daiichi Sankyo in collaboration with AstraZeneca and ... Trastuzumab deruxtecan is a HER2-directed antibody attached to a topoisomerase inhibitor that is approved for
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … ENHERTU POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/VIAL …
Fenthion is an organothiophosphate drug used as an insecticide, avicide, and acaricide. Its mode of action is explained by cholinesterase enzyme inhibition, which is similar to other organophosphates. Fenthion is listed as a restricted use compound by the United States Environmental Protection Agency due to its potential to cause cholinesterase...
Vet approved
Matched Synonyms: … Phosphorothioic acid, O,O-dimethyl O-(3-methyl-4-(methylthio)phenyl) ester …
Matched Description: … Fenthion is an _organothiophosphate_ drug used as an insecticide, avicide, and acaricide. ... States Environmental Protection Agency due to its potential to cause cholinesterase inhibition in humans and
Pabinafusp alfa is under investigation in clinical trial NCT03568175 (A Study of JR-141 in Patients With Mucopolysaccharidosis II).
Investigational
Matched Synonyms: … HUMAN-MUS MUSCULUS MONOCLONAL JR-141 .GAMMA.1-CHAIN) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC 2-AMINO ACID
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Paliperidone is the primary active metabolite of risperidone. The mechanism of action is unknown but it is likely to act via a similar pathway to risperidone. It has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and serotonin...
Approved
Matched Description: … Paliperidone is also active as an antagonist at alpha 1 and alpha 2 adrenergic receptors and H1 histaminergic ... therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and ... extended-release tablet, a once-monthly intramuscular injection, an every-three-month intramuscular injection, and
Matched Products: … INVEGA Sustenna Prolonged Release Suspension for IM Injection 50mg/0.5 ml ... INVEGA Sustenna Prolonged Release Suspension for IM Injection 75mg/0.75ml ... INVEGA TRINZA PROLONGED RELEASE SUSPENSION FOR IM INJECTION 350MG/1.75ML …
Experimental
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Scabicides, Insecticides and Repellents …
Matched Products: … BI-SOL FORT SAMPUAN, 60 ML …
Chondroitin sulfate is a glycosaminoglycan considered as a symptomatic slow-acting drug for osteoarthritis (SYSADOA). The SYSADOA status suggested a pain relief and increased joint mobility after a relative long regular administration, as well as a long-lasting effect after the end of the treatment. Chondroitin sulfate is composed of alternating 1,3-N-acetyl-β-d-galactosamine...
Approved
Investigational
Nutraceutical
Matched Description: … acid units which bear 4-O- and/or 6-O-sulfations at the N-acetylgalactosamine units disposed of in specific ... [A7906] The SYSADOA status suggested a pain relief and increased joint mobility after a relative long ... Chondroitin sulfate is composed of alternating 1,3-N-acetyl-β-d-galactosamine and 1,4-β-d-glucuronic …
Matched Mixtures name: … Blackmores Joint Formula with Glucosamine and Chondroitin ... FLEXURE®CAPSULA DE GELATINA ... FLEXURE®CAPSULA DE GELATINA …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … HIRUDOID FORT %0,445 JEL, 40 G ... HIRUDOID FORT %0,445 KREM, 40 G …
Tocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and autoimmune conditions. It was first described in the literature in 2003 when Chugai, a subsidiary of Roche began developing IL-6 inhibiting monoclonal antibodies. Tocilizumab was granted FDA approval on 8 January 2010 to treat a...
Approved
Matched Description: … [L40164] Subsequently, it was granted approval by Health Canada and the FDA in October [L43697] and December ... Tocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and ... autoimmune disorders, such as different types of arthritis and cytokine release syndrome. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Biologics for Rheumatoid Arthritis Treatment ... Experimental Unapproved Treatments for COVID-19 …
Matched Products: … Actemra Concentrate for Solution for Infusion 20mg/ml ... ACTEMRA 20 MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION. ... ACTEMRA (162 MG SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE) …
An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
Approved
Investigational
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Ganciclovir and prodrug ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors ... Antivirals for Systemic Use …
Matched Products: … CYMEVENE 500MG powder for concentrate for solution for infusion ... Ganciclovir for Injection ... GANCICLOVIR SODIUM FOR INJECTION …
Insulin glargine is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … a build-up of ketone acids in the blood and a syndrome called ketoacidosis, which is a life-threatening ... The resulting protein is soluble at pH 4 and forms microprecipitates at physiological pH 7.4 allowing ... Insulin glargine is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type …
Matched Mixtures name: … Soliqua SoloStar 100units/mL+33mcg/mL solution for injection in a pre-filled pen ... SOLIQUA SOLUTION FOR INJECTION IN A PRE-FILLED PEN 100UNITS/ML + 50MCG/ML ... SOLIQUA SOLUTION FOR INJECTION IN A PRE-FILLED PEN 100UNITS/ML + 33MCG/ML …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... insulin glargine and lixisenatide ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Glaritus 100 IU/mL Solution for injection ... solution for Injection in vial 100 Units/ml ... BASALOG 100 IU/mL, SOLUTION FOR INJECTION IN A VIAL …
Displaying drugs 2926 - 2950 of 3344 in total