Displaying drugs 3001 - 3025 of 9437 in total
20-Hydroxyecdysone
Investigational
Matched Synonyms: … Cholest-7-en-6-one, 2,3,14,20,22,25-hexahydroxy-, (2.beta.,3.beta.,5.beta.,22r)- …
Matched Iupac: … (1S,3aS,5aR,7R,8S,9aR,9bR,11aR)-3a,7,8-trihydroxy-9a,11a-dimethyl-1-[(2R,3R)-2,3,6-trihydroxy-6-methylheptan …
Matched Iupac: … (1S,3aS,5aR,7R,8S,9aR,9bR,11aR)-3a,7,8-trihydroxy-9a,11a-dimethyl-1-[(2R,3R)-2,3,6-trihydroxy-6-methylheptan …
Vebicorvir
Investigational
Matched Synonyms: … 5,5,11-trioxo-n-((2-(trifluoromethyl)-1,3-thiazol-5-yl)methyl)-10,11-dihydro-5h- 5.lambda.6-dibenzo(b …
Cadisegliatin
Cadisegliatin is under investigation in clinical trial NCT06334133 (Cadisegliatin as Adjunctive Therapy in Type 1 Diabetes).
Investigational
Matched Synonyms: … 2-((2-(3-cyclohexyl-3-((1r,4r)-4-propoxycyclohexyl)ureido)thiazol-5-yl)thio)acetic acid ... [(2-{[cyclohexyl(trans-4-propoxycyclohexyl)carbamoyl]amino}-1,3-thiazol-5-yl)sulfanyl]acetic acid …
Matched Description: … Cadisegliatin is under investigation in clinical trial NCT06334133 (Cadisegliatin as Adjunctive Therapy in Type 1 …
Matched Description: … Cadisegliatin is under investigation in clinical trial NCT06334133 (Cadisegliatin as Adjunctive Therapy in Type 1 …
Quinacrine
An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
Investigational
Matched Synonyms: … 3-chloro-7-methoxy-9-(1-methyl-4-diethylaminobutylamino)acridine ... 6-chloro-9-((4-(diethylamino)-1-methylbutyl)amino)-2-methoxyacridine …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Soquelitinib
Investigational
Matched Synonyms: … Cyclopropanecarboxamide, N-[5-[[5-[[(3R)-hexahydro-3-methyl-4-(1-oxo-2-propen-1-yl)-1H-1,4-diazepin-1 ... ]-1,3-thiazol-2-yl}cyclopropanecarboxamide ... N-{5-[(5-{[(3R)-4-(prop-2-enoyl)-3-methyl-1,4-diazepan-1-yl]carbonyl}-4-methoxy-2-methylphenyl)sulfanyl …
Tozuleristide
Tozuleristide is under investigation in clinical trial NCT02464332 (Safety Study of BLZ-100 in Adult Subjects With Sarcoma Undergoing Surgery).
Investigational
Matched Synonyms: … N6.27-(6-(2-(7-(1,1-DIMETHYL-3-(4-SULFONATOBUTYL)-1H-BENZO(E)INDOL-1-IUM-2-YL)HEPTA-2,4,6-TRIENYLIDENE ... )-1,1-DIMETHYL-1,2-DIHYDRO-3H-BENZO(E)INDOL-3-YL)HEXANOYL)(15-ARGININE(K>R),23-ARGININE(K>R))CHLOROTOXIN …
Reveglucosidase alfa
Investigational
Matched Synonyms: … Des-(2-7)-human insulin-like growth factor ii fusion protein with glycyl-l-alanyl-l-prolyl-human lysosomal …
Edotreotide yttrium Y-90
Investigational
Matched Synonyms: … (2-7)disulfide ... Y-90 dota-tyr(3)-octreotide ... Yttrium Y-90 n-((4,7,10-triscarboxymethyl-1,4,7,10-tetraazacyclododec-1-yl)acetyl)-d-phe-cys-tyr-d-trp-lys-thr-cys-thr …
Matched Iupac: … (90Y)yttrium(3+) 2-[4-({[(1R)-1-{[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-4-{[(2R,3R)-1,3-dihydroxybutan ... -2-yl]carbamoyl}-7-[(1R)-1-hydroxyethyl]-16-[(4-hydroxyphenyl)methyl]-13-[(1H-indol-3-yl)methyl]-6,9,12,15,18 ... carbamoyl}-2-phenylethyl]carbamoyl}methyl)-7,10-bis(carboxylatomethyl)-1,4,7,10-tetraazacyclododecan-1- …
Matched Iupac: … (90Y)yttrium(3+) 2-[4-({[(1R)-1-{[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-4-{[(2R,3R)-1,3-dihydroxybutan ... -2-yl]carbamoyl}-7-[(1R)-1-hydroxyethyl]-16-[(4-hydroxyphenyl)methyl]-13-[(1H-indol-3-yl)methyl]-6,9,12,15,18 ... carbamoyl}-2-phenylethyl]carbamoyl}methyl)-7,10-bis(carboxylatomethyl)-1,4,7,10-tetraazacyclododecan-1- …
H3B-8800
H3B-8800 is a novel spliceosome inhibitor developed by H3 Biomedicine . It offers the benefit of preferentially killing spliceosome-mutant cancer cells whereas other splicesome inhibitors, such as the pladienolide analogue E7107, show no such preferential targeting . H3B-8800 was granted orphan drug status by the FDA in August 2017 and...
Investigational
Matched Synonyms: … )-1-METHYL-5-(2-PYRIDINYL)-1,3-HEXADIEN-1-YL)-12-OXOOXACYCLODODEC-4-EN-6-YL ESTER ... 3,7-dimethyl-12-oxo-2-[(2E,4E,6R)-6-(2-pyridinyl)-2,4-heptadien-2-yl]oxacyclododec-4-en-6-yl 4-methyl-1- ... 12-Oxo-2-[(2E,4E,6R)-6-(Pyridin-2-Yl)Hepta-2,4-Dien-2-Yl]Oxacyclododec-4-En-6-Yl 4-Methylpiperazine-1- …
Matched Iupac: … oxacyclododec-4-en-6-yl 4-methylpiperazine-1-carboxylate ... 3S,4E,6S,7R,10R)-7,10-dihydroxy-3,7-dimethyl-12-oxo-2-[(4E,6R)-6-(pyridin-2-yl)hepta-2,4-dien-2-yl]-1- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … oxacyclododec-4-en-6-yl 4-methylpiperazine-1-carboxylate ... 3S,4E,6S,7R,10R)-7,10-dihydroxy-3,7-dimethyl-12-oxo-2-[(4E,6R)-6-(pyridin-2-yl)hepta-2,4-dien-2-yl]-1- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Folitixorin
Investigational
Matched Synonyms: … L-glutamic acid, n-(4-(3-amino-1,2,5,6,6a,7-hexahydro-1-oxoimidazo(1,5-f)pteridin-8(9h)-yl)benzoyl)- …
Matched Iupac: … (2S)-2-[(4-{3-amino-1-oxo-1H,2H,5H,6H,6aH,7H,8H,9H-imidazo[1,5-f]pteridin-8-yl}phenyl)formamido]pentanedioic …
Matched Iupac: … (2S)-2-[(4-{3-amino-1-oxo-1H,2H,5H,6H,6aH,7H,8H,9H-imidazo[1,5-f]pteridin-8-yl}phenyl)formamido]pentanedioic …
Apramycin
Apramycin is an aminoglycoside antibiotic and has a bactericidal action against many gram-negative bacteria. Apramycin is a structurally unique antibiotic that contains a bicyclic sugar moiety and a monosubstituted deoxystreptamine. It is not approved for use in humans.
Experimental
Vet approved
Matched Synonyms: … -1,5:8,4-dipyranos-1-yl)-2-deoxy-D-streptamine ... 4-O-((8R)-2-amino-8-O-(4-amino-4-deoxy-α-D-glucopyranosyl)-2,3,7-trideoxy-7-(methylamino)-D-glycero-α-D-allo-octodialdo …
Matched Iupac: … ]oxy}-4-hydroxy-3-(methylamino)-octahydropyrano[3,2-b]pyran-2-yl]oxy}-5-amino-6-(hydroxymethyl)oxane- ... (2R,3R,4S,5S,6S)-2-{[(2R,3S,4R,4aR,6S,7R,8aS)-7-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl …
Matched Iupac: … ]oxy}-4-hydroxy-3-(methylamino)-octahydropyrano[3,2-b]pyran-2-yl]oxy}-5-amino-6-(hydroxymethyl)oxane- ... (2R,3R,4S,5S,6S)-2-{[(2R,3S,4R,4aR,6S,7R,8aS)-7-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl …
Bazlitoran
Bazlitoran is under investigation in clinical trial NCT02092909 (Phase 1/2 Dose Escalation Study in Patients With Relapsed or Refractory Waldenstrom's Macroglobulinemia).
Investigational
Matched Synonyms: … Antagonist of the endosomal Toll-like receptors (TLRs) 7, 8, and 9 ... ALL-P-AMBO-2'-DEOXY-P-THIOCYTIDYLYL-(3'->5')-P-THIOTHYMIDYLYL-(3'->5')-2'-DEOXY-P-THIOADENYLYL-(3'->5 ... ')-P-THIOTHYMIDYLYL-(3'->5')-2'-DEOXY-P-THIOCYTIDYLYL-(3'->5')-P-THIOTHYMIDYLYL-(3'->5')-2'-O-METHYL-P-THIOGUANYLYL …
Matched Description: … Bazlitoran is under investigation in clinical trial NCT02092909 (Phase 1/2 Dose Escalation Study in Patients …
Matched Salts cas: … 1613607-40-1 …
Matched Description: … Bazlitoran is under investigation in clinical trial NCT02092909 (Phase 1/2 Dose Escalation Study in Patients …
Matched Salts cas: … 1613607-40-1 …
Taniraleucel
Investigational
Matched Synonyms: … expanded and differentiated in the presence of cytokines including thrombopoietin, SCF, Flt3 ligand, IL-7, …
Delpazolid
Delpazolid (LCB01-0371) is under investigation in clinical trial NCT01554995 (A Clinical Study, Randomized, Double-blind, Placebo-controlled, Single Dose Study).
Investigational
Matched Synonyms: … (5R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(hydroxymethyl)-1,3-oxazolidin ... (5R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one ... 2-oxazolidinone, 3-(4-(5,6-dihydro-1-methyl-1,2,4-triazin-4(1H)-yl)-3-fluorophenyl)-5-(hydroxymethyl) …
Matched Iupac: … (5R)-3-[3-fluoro-4-(1-methyl-1,4,5,6-tetrahydro-1,2,4-triazin-4-yl)phenyl]-5-(hydroxymethyl)-1,3-oxazolidin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … (5R)-3-[3-fluoro-4-(1-methyl-1,4,5,6-tetrahydro-1,2,4-triazin-4-yl)phenyl]-5-(hydroxymethyl)-1,3-oxazolidin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Fenvalerate
Investigational
Matched Synonyms: … methyl (R)-4-((3S,5R,7R,8R,9S,10S,13R,14S,17R)-7-hydroxy-10,13-dimethyl-3-((4-((pyridin-3- ylmethyl)amino ... .-(1-methylethyl)-, cyano(3-phenoxyphenyl)methyl ester ... Cyano(3-phenoxyphenyl)methyl 4-chloro-.alpha.-(1-methylethyl)benzeneacetate …
Matched Iupac: … cyano(3-phenoxyphenyl)methyl 2-(4-chlorophenyl)-3-methylbutanoate …
Matched Iupac: … cyano(3-phenoxyphenyl)methyl 2-(4-chlorophenyl)-3-methylbutanoate …
AP-102
Investigational
Matched Synonyms: … -, cyclic (2->7)-disulfide ... H-(4-amino-3-iodo)-d-phe-c(cys-(3-iodo)-tyr-d-trp-lys-val-cys)-thr-nh2 ... H-(4-amino-3-iodo)-D-Phe-c[Cys-(3-iodo)-Tyr-D-Trp-Lys-Val-Cys]-Thr-NH2 …
Matched Iupac: … )-16-[(4-hydroxy-3-iodophenyl)methyl]-13-[(1H-indol-3-yl)methyl]-6,9,12,15,18-pentaoxo-7-(propan-2-yl ... (2S,3R)-2-{[(4R,7S,10S,13R,16S,19R)-19-[(2R)-2-amino-3-(4-amino-3-iodophenyl)propanamido]-10-(4-aminobutyl ... )-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]formamido}-3-hydroxybutanamide …
Matched Iupac: … )-16-[(4-hydroxy-3-iodophenyl)methyl]-13-[(1H-indol-3-yl)methyl]-6,9,12,15,18-pentaoxo-7-(propan-2-yl ... (2S,3R)-2-{[(4R,7S,10S,13R,16S,19R)-19-[(2R)-2-amino-3-(4-amino-3-iodophenyl)propanamido]-10-(4-aminobutyl ... )-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]formamido}-3-hydroxybutanamide …
3D-185 free base
Investigational
Matched Synonyms: … Benzamide, N-(6-(2,6-dichloro-3,5-dimethoxyphenyl)-1H-pyrazolo(3,4-B)pyridin-3-yl)-4-(3,3-dimethyl-1- …
OCU-100
Investigational
Matched Synonyms: … LEDGF(1-326) ... Lens epithelial derived growth factor (1-326) …
Zelpultide alfa
Zelpultide alfa is a recombinant human surfactant protein D.
Investigational
Matched Synonyms: … HUMAN PULMONARY SURFACTANT-ASSOCIATED PROTEIN D (PSPD, SURFACTANT PROTEIN D, SP-D, COLLECTIN-7, SURFACTANT …
MK-3207
Mk3207 has been used in trials studying the treatment of Migraine and Migraine Disorders.
Investigational
Matched Iupac: … 2-[(8R)-8-(3,5-difluorophenyl)-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]-N-[(2R)-2'-oxo-1,1',2',3-tetrahydrospiro …
JPC-3210
JPC-3210 is a potent antimalarial agent. It is an erythrocytic schizonticide with potent in vitro antimalarial activity against multidrug-resistant Plasmodium falciparum lines, low cytotoxicity, potent in vivo efficacy against murine malaria, and favourable preclinical pharmacokinetics including a lengthy plasma elimination half-life.
Experimental
Matched Iupac: … 4-tert-butyl-2-[(tert-butylamino)methyl]-6-[5-fluoro-6-(trifluoromethyl)pyridin-3-yl]phenol …
Valemetostat
Investigational
Matched Iupac: … (2R)-7-chloro-N-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-2,4-dimethyl-2-[(1r,4R)-4-(dimethylamino ... )cyclohexyl]-2H-1,3-benzodioxole-5-carboxamide …
Matched Salts cas: … 1809336-93-3 …
Matched Salts cas: … 1809336-93-3 …
Erbumine
Investigational
Matched Synonyms: … 1-((3-chloro-2-fluorophenyl)methyl)-4-((3-fluoro-6-((5-methyl-1h-pyrazol-3-yl)amino)-2-pyridinyl)methyl ... 4-piperidinecarboxylic acid, 1-((3-chloro-2-fluorophenyl)methyl)-4-((3-fluoro-6-((5-methyl-1h-pyrazol ... -3-yl)amino)-2-pyridinyl)methyl)-2-methyl-, (2r,4r)- …
Matched Iupac: … (2R,4R)-1-[(3-chloro-2-fluorophenyl)methyl]-4-({3-fluoro-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyridin-2 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … (2R,4R)-1-[(3-chloro-2-fluorophenyl)methyl]-4-({3-fluoro-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyridin-2 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
N,N-[2,5-O-[Dibenzyl]-glucaryl]-DI-[isoleucyl-amido-methane]
Experimental
Matched Iupac: … (2R,3R,4R,5R)-2,5-bis(benzyloxy)-3,4-dihydroxy-N,N'-bis[(1S,2S)-2-methyl-1-(methylcarbamoyl)butyl]hexanediamide …
CT-001
Investigational
Displaying drugs 3001 - 3025 of 9437 in total