Advanced Filter

Filter by Group

Filter by Market Availability

Displaying drugs 3101 - 3125 of 3311 in total
Hyaluronidase is an enzyme used to improve the absorption and dispersion of parenterally administered fluids, drugs, and contrast agents. The action of hyaluronidase was first described in 1936, and named in 1939. Early research into hyaluronidase identified it as a "spreading factor" which allowed for increased permeability of the connective...
Approved
Matched Description: … fluids, drugs, and contrast agents. ... Hyaluronidase is an enzyme used to improve the absorption and dispersion of parenterally administered ... [L13338] The action of hyaluronidase was first described in 1936, and named in 1939. …
Matched Categories: … Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Matched Products: … HYALASE POWDER FOR INJECTION 1500 iu/ampoule …
Experimental
Matched Name: … }ami no)pentanedioic acid ... dihydroxy-5-[(phosphonooxy)methyl]tetrahydro-2-furanyl}amino)-2-oxoethyl]amino}-2-hydroxy-2-propanyl]benzoyl
Matched Iupac: … phosphonooxy)methyl]oxolan-2-yl]carbamoyl}methyl)amino]-2-hydroxypropan-2-yl]phenyl}formamido)pentanedioic acid
Indacaterol is a novel, ultra-long-acting, rapid onset β(2)-adrenoceptor agonist developed for Novartis for the once-daily management of asthma and chronic obstructive pulmonary disease. It was approved by the European Medicines Agency (EMA) on 30 November 2009 and by the FDA on 1 July 2011. It is marketed in Europe as...
Approved
Matched Description: … Indacaterol is provided as its maleate salt form. ... for the once-daily management of asthma and chronic obstructive pulmonary disease. ... It is marketed in Europe as Onbrez and in America as Arcapta Neohaler. …
Matched Categories: … indacaterol and mometasone ... indacaterol and glycopyrronium bromide ... indacaterol, glycopyrronium bromide and mometasone ... Drugs for Obstructive Airway Diseases …
Matched Products: … Onbrez Breezhaler Powder for inhalation Hard Capsule 300 mcg ... Onbrez Breezhaler Powder for Inhalation Hard Capsule 150 mcg …
Kanamycin (also known as kanamycin A) is an aminoglycoside bacteriocidal antibiotic, available in oral, intravenous, and intramuscular forms, and used to treat a wide variety of infections. Kanamycin is isolated from the bacterium Streptomyces kanamyceticus and its most commonly used form is kanamycin sulfate.
Approved
Investigational
Vet approved
Matched Description: … intramuscular forms, and used to treat a wide variety of infections. ... Kanamycin is isolated from the bacterium Streptomyces kanamyceticus and its most commonly used form is ... known as kanamycin A) is an aminoglycoside bacteriocidal antibiotic, available in oral, intravenous, and
Matched Categories: … Alimentary Tract and Metabolism ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … KANAMYCIN MEIJI FOR INJECTION 1 g/vial …
Ganirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist. Derived from endogenous GnRH, ganirelix has amino acid substitutions. Ganirelix is indicated for controlled ovarian hyperstimulation in assisted reproduction techniques. The first case of pregnancy achieved after the use of ganirelix in an assisted reproduction program was reported...
Approved
Matched Description: … Ganirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist ... Derived from endogenous GnRH, ganirelix has amino acid substitutions. ... Ganirelix is indicated for controlled ovarian hyperstimulation in assisted reproduction techniques. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … ORGALUTRAN 0.25MG/0.5ML (SOLUTION FOR INJECTION) ... ORGALUTRAN SOLUTION FOR INJECTION 0.25 mg/0.5 ml …
Polymyxin B was discovered in the 1940s . They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes . Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic[A176426,FDA Label]. All gram-positive bacteria, fungi, and the gram-negative cocci,...
Approved
Vet approved
Matched Description: … They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes ... Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic ... It is appropriate for treatment of infections of the urinary tract, meninges, and blood stream, caused …
Matched Mixtures name: … Small Cuts and Burns ... ACME Small Cuts and Burns ... Triple Antibiotic and Burn Relief …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Pore Forming Cytotoxic Proteins ... Ophthalmological and Otological Preparations ... Antibacterials for Systemic Use …
Matched Products: … Polymyxin B for Injection USP ... POLY-MxB for Injection U.S.P. 500,000 Units (Lyophilized) …
Levosimendan increases calcium sensitivity to myocytes by binding to troponin C in a calcium dependent manner. This increases contractility without raising calcium levels. It also relaxes vascular smooth muscle by opening adenosine triphosphate sensitive potassium channels. Levosimendan is used to manage acutely decompensated congestive heart failure.
Approved
Investigational
Matched Description: … Levosimendan increases calcium sensitivity to myocytes by binding to troponin C in a calcium dependent ... This increases contractility without raising calcium levels. …
Matched Products: … SIMDAX 2.5 MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION …
Etilefrine is an adrenergic agonist that appears to interact with beta-1 and some alpha-adrenergic receptors. It has been used as a vasoconstrictor agent.
Approved
Withdrawn
Matched International brands: … Tonus-Forte
Matched Description: … Etilefrine is an adrenergic agonist that appears to interact with beta-1 and some alpha-adrenergic receptors …
Matched Categories: … Adrenergic and Dopaminergic Agents …
Myasthenia gravis is an autoimmune disease involving dysfunction at the neuromuscular junction, most commonly due to autoantibodies directed against the acetylcholine receptor (AChR), which results in muscle tone loss, muscle weakness, and fatigue. Acetylcholinesterase inhibitors have been the symptomatic treatment of choice in myasthenia gravis since the 1930s with the...
Approved
Investigational
Matched International brands: … Kalymin forte
Matched Description: … Possible dose forms have been expanded to include extended-release tablets, syrups, and injections, marketed ... under various brand and generic names. ... directed against the acetylcholine receptor (AChR), which results in muscle tone loss, muscle weakness, and
Cetuximab is a recombinant chimeric human/mouse IgG1 monoclonal antibody that competitively binds to epidermal growth factor receptor (EGFR) and competitively inhibits the binding of epidermal growth factor (EGF). EGFR is a member of the ErbB family of receptor tyrosine kinases found in both normal and tumour cells; it is responsible...
Approved
Matched Description: … cells; it is responsible for regulating epithelial tissue development and homeostasis. ... [A227963] Approved by the FDA in February 2004 under the brand name ERBITUX, cetuximab is used for ... the treatment of head and neck cancer and metastatic, KRAS wild-type colorectal cancer, and metastatic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … ERBITUX 5MG/ML SOLUTION FOR INFUSION …
Magnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can be extracted from brine or sea water.
Approved
Matched Description: … Magnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can …
Matched Mixtures name: … Dianeal Pd4 Capd Solution With 1.5% Dextrose and 2.5meq/l Calcium ... Dianeal Pd4 Capd Solution With 2.5% Dextrose and 2.5meq/l Calcium ... Dianeal Pd4 Capd Solution With 4.25% Dextrose and 2.5meq/l Calcium
Matched Categories: … Blood and Blood Forming Organs ... Alimentary Tract and Metabolism ... Blood Substitutes and Perfusion Solutions …
Matched Products: … Magnesium Chloride for Hemodialysis 5.15 …
Experimental
Matched Name: … 7A-DIMETHYL-4-OXY-OCTAHYDRO-1-OXA-4-AZA-CYCLOPROPA[A]NAPHTHALEN-4-YL) -ACETYLAMINO]-PHENYLCARBAMOYL}-BUTYRIC ACID
Approved
Experimental
Matched Iupac: … 2-(2-{2-[2-(benzoylsulfanyl)acetamido]acetamido}acetamido)acetic acid
Matched Products: … Kit for the Preparation of Technetium Tc99m Mertiatide …
Ephedrine was first described in western literature in 1888, as a naturally occurring component of the ephedra plant, along with pseudoephedrine. Ephedrine acts as both a direct and indirect sympathomimetic. It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of norepinephrine from sympathetic neurons,...
Approved
Matched Description: … [A193650,L12972] Ephedrine is used for its vasoconstrictive, positive chronotropic, and positive inotropic ... [A193698] Ephedrine acts as both a direct and indirect sympathomimetic. ... It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of …
Matched Mixtures name: … UNISEDYL FORTE LINCTUS ... COUGHLAX FORTE SYRUP ... SUNSEDYL FORTE COUGH LINCTUS …
Matched Categories: … Adrenergics for Systemic Use ... Adrenergic and Dopaminergic Agents ... Drugs for Obstructive Airway Diseases ... Alimentary Tract and Metabolism ... Alpha-and Beta-adrenergic Agonists …
Matched Products: … EPHEDRINE AGUETTANT SOLUTION FOR INJECTION 30MG/ML ... MARTINDALE PHARMA EPHEDRINE HYDROCHLORIDE SOLUTION FOR INJECTION 30MG/ML …
Investigational
Matched Synonyms: … (s)-1-(3,4-difluorophenyl)-6-(5-(3,5-dimethylisoxazol-4-yl)-1-((1r,4s)-4-methoxycyclohexyl)-1h-benzo( …
Alanyl Glutamine is under investigation in clinical trial NCT00338221 (Clinical Trial of Alanyl-Glutamine or Glycine in Children With Persistent Diarrhea or Malnutrition).
Investigational
Matched Iupac: … (2S)-2-[(2S)-2-aminopropanamido]-4-carbamoylbutanoic acid
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... Amino Acids ... Blood Substitutes and Perfusion Solutions …
Matched Products: … Kipo for IV Infusion 200 mg/ml …
Tenecteplase is a tissue plasminogen activator (tPA) developed from modifications of natural human tPA complementary DNA (cDNA). It is a 527 amino acid with a substitution of threonine 103 with asparagine and substitution of asparagine 117 with glutamine within the kringle 1 domain, and a tetra-alanine substitution at amino acids...
Approved
Matched Description: … It is a 527 amino acid with a substitution of threonine 103 with asparagine and substitution of asparagine ... 117 with glutamine within the kringle 1 domain, and a tetra-alanine substitution at amino acids 296- …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Matched Products: … METALYSE FOR INJECTION 10,000 u/vial …
Linezolid is a synthetic antibiotic which is used for the treatment of infections caused by aerobic Gram-positive bacteria. Its effects are bacteriostatic against both enterococci and staphylococci and bactericidal against most isolates of streptococci. Linezolid exerts its antibacterial activity by inhibiting the initiation of bacterial protein synthesis - more specifically,...
Approved
Investigational
Matched Description: … Its effects are bacteriostatic against both enterococci and staphylococci and bactericidal against most ... generally more effective and tolerable than its predecessor. ... synthesis - more specifically, it binds to the 23S ribosomal RNA of the 50S subunit[A11227,A199050] and
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Products: … ZYVOX SOLUTION FOR INFUSION 2 mg/ml ... CINEZOLID solution for infusion 2mg/mL ... ZYVOX 20MG/ML GRANULES FOR ORAL SUSPENSION …
Experimental
Matched Name: … Benzothiazol-2-Yl)-2-(1h-1,2,3-Benzotriazol-1-Yl)-5-Phenylpent-4-Enyl]Phenyl}(Difluoro)Methylphosphonic Acid
Matched Iupac: … benzothiazol-2-yl)-2-(1H-1,2,3-benzotriazol-1-yl)-5-phenylpent-4-en-1-yl]phenyl}difluoromethyl)phosphonic acid
Experimental
Matched Name: … 2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-3-METHYL-BUTYRIC ACID
Matched Iupac: … [4-(2-{2-amino-4-oxo-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}ethyl)phenyl]formamido}-3-methylbutanoic acid
Urokinase is an endogenous peptide that is cleaved in the presence of plasmin between lysine 158 and isoleucine 159 to yield active urokinase. Urokinase remains connected between these 2 chains by a sulfhydryl bond. Urokinase was granted FDA approval on 16 January 1978.
Approved
Investigational
Withdrawn
Matched Description: … Urokinase is an endogenous peptide that is cleaved in the presence of plasmin between lysine 158 and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Matched Products: … Kinlytic (urokinase for Injection) …
Pholcodine formula is 3-o-morpholinoethylmorphine and it is classified as an antitussive which is defined as an opioid cough suppressant. It belongs to the opioid family of compounds and it is widely used. Pholcodine activity is the suppression of unproductive cough and it also has a mild sedative effect with little...
Approved
Illicit
Matched Description: … It belongs to the opioid family of compounds and it is widely used. ... Pholcodine formula is 3-o-morpholinoethylmorphine and it is classified as an antitussive which is defined ... [A31738] Pholcodine activity is the suppression of unproductive cough and it also has a mild sedative …
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives …
Matched Products: … Pholcodyl Forte Syrup ... Ducodin Forte Linctus 15mg/5ml ... Tussedyl Forte Syrup 15mg/5ml …
Quinidine is a D-isomer of quinine present in the bark of the Cinchona tree and similar plant species. This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication.[A38016,A250050] Quinidine is considered the first antiarrhythmic drug (class Ia) and is moderately efficacious in the acute...
Approved
Investigational
Matched Description: … Quinidine is a D-isomer of [quinine] present in the bark of the Cinchona tree and similar plant species ... This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication. ... [A38016] It prolongs cellular action potential by blocking sodium and potassium currents. …
Matched Categories: … Quinine and stereoisomer ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … Quinidine Gluconate for Inj 80mg/ml USP …
Investigational
Matched Synonyms: … 6S)-4,5-dihydroxy-2-(hydroxymethyl)-6-(((6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo
Matched Iupac: … 2-{[(2S,3R,4S,5R,6R)-2-{[(2R,3S,4R,5R,6S)-6-{[(6aR,10aR)-6,6,9-trimethyl-3-pentyl-6H,6aH,7H,8H,10aH-benzo
Matched Categories: … Cannabinoids and similars …
Refractory anaplastic astrocytoma (WHO grade III) and Glioblastoma multiforme (WHO grade IV) are primary malignant brain tumours with poor prognosis and limited treatment options. Despite considerable genetic heterogeneity, these tumours often have impaired DNA repair systems, rendering them initially sensitive to alkylating agents, although they invariably develop resistance to these...
Approved
Investigational
Matched Description: … [A229848, A229858, L32033] Temozolomide is an imidazotetrazine prodrug that is stable at acidic pH but ... Refractory anaplastic astrocytoma (WHO grade III) and Glioblastoma multiforme (WHO grade IV) are primary ... both oral and intravenous administration. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … MOZOLA® 20MG CAPSULA
Displaying drugs 3101 - 3125 of 3311 in total