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Displaying drugs 3126 - 3150 of 3888 in total
TBI-223 is under investigation in clinical trial NCT06192160 (Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis).
Investigational
Matched Synonyms: … CARBAMIC ACID, N-(((5S)-3-(3-FLUORO-4-(2-OXA-6-AZASPIRO(3.3)HEPT-6-YL)PHENYL)-2-OXO-5-OXAZOLIDINYL)METHYL …
Matched Description: … TBI-223 is under investigation in clinical trial NCT06192160 (Trial of Novel Regimens for the Treatment …
Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. Ramiprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII)....
Approved
Matched Synonyms: … 2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid
Matched Iupac: … [(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-octahydrocyclopenta[b]pyrrole-2-carboxylic acid
Matched Description: … It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. ... ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... Ramipril may be used in the treatment of hypertension, congestive heart failure, nephropathy, and to …
Matched Mixtures name: … Hypren plus HCT forte 5 mg/25 mg Tabletten ... Lannapril plus forte - Tabletten ... PMS-ramipril-hctz …
Matched Categories: … simvastatin, acetylsalicylic acid and ramipril ... atorvastatin, acetylsalicylic acid and ramipril ... Antihypertensive Agents Indicated for Hypertension ... ACE Inhibitors and Calcium Channel Blockers ... ACE Inhibitors and Diuretics …
Matched Products: … PMS-ramipril ... Prv-ramipril ... Pro-ramipril - 5 …
Technetium Tc-99m tilmanocept is a radiopharmaceutical diagnostic imaging agent approved by the U.S. Food and Drug Administration (FDA) for the imaging of lymph nodes with or without scintigraphic imaging. It is a macromolecule consisting of multiple units of diethylenetriaminepentaacetic acid (DTPA) and mannose, each covalently attached to a 10 kDa...
Approved
Investigational
Matched Description: … It is a macromolecule consisting of multiple units of diethylenetriaminepentaacetic acid (DTPA) and mannose ... Food and Drug Administration (FDA) for the imaging of lymph nodes with or without scintigraphic imaging ... DTPA serves as a chelating agent for technetium Tc 99m to bind [FDA Label]. …
Matched Products: … Kit for the preparation of Lymphoseek (technetium Tc 99m tilmanocept) …
CL-315585 is the D isomer of Verteporfin.
Approved
Matched Synonyms: … 23h,25h-benzo(b)porphine-9,13-dipropanoic acid, 18-ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19 ... 23h,25h-benzo(b)porphine-9,13-dipropanoic acid, 18-ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19 …
A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.
Approved
Matched Synonyms: … thiazolyl)(((2S,3S,)-2-methyl-4-oxo-1-sulfo-3-azetidinyl)carbamoyl)methylene)amino)oxy)-2-methylpropionic acid ... {[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino} -2- oxoethylidene]amino}oxy)-2-methylpropanoic acid
Matched Description: … , bladder, and kidneys. ... It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … AZACTAM FOR INJECTION 1 g/vial …
Acromegaly is a disorder caused by excess growth hormone (GH), increasing the growth of body tissues and causing metabolic dysfunction. In most cases, it results from an anterior pituitary growth hormone-releasing tumor. Typically, the feet, hands, and face grow abnormally large; organomegaly and insulin resistance may also occur. Acromegaly is...
Approved
Investigational
Matched Description: … [L14513] Additionally, it is used for the treatment of acromegaly and symptoms arising from various tumors ... Typically, the feet, hands, and face grow abnormally large; organomegaly and insulin resistance may also ... Acromegaly is a disorder caused by excess growth hormone (GH), increasing the growth of body tissues and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Somatostatin and Analogues ... Sex Hormones and Insulins ... P-glycoprotein substrates …
Matched Products: … BYNFEZIA Pen ... SANDOSTATIN LAR FOR INJECTION 10 mg ... SANDOSTATIN LAR FOR INJECTION 20 mg …
Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. First approved in the United States in November 2002 and in Europe in April 2003, teriparatide makes the first approved drug in...
Approved
Investigational
Matched Synonyms: … PTH 1-34 ... PTH (1-34) …
Matched Description: … Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. ... [A251395] It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. ... [A251395] First approved in the United States in November 2002 and in Europe in April 2003,[A251400] …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Calcium-Regulating Hormones and Agents ... Parathyroid Hormones and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SONDELBAY (Teriparatide) 20 micrograms/ 80 microliters solution for injection in pre-filled pen ... FORTEO 250 UG SOLUTION FOR INJECTION ... MEGAPTH-G Teriparatide 20 micrograms / 80 microliters solution for injection …
Dinoprostone is a naturally occurring prostaglandin E2 (PGE2). It has important effects in labour. It also stimulates osteoblasts to release factors which stimualtes bone resorption by osteoclasts. As a prescription drug it is used as a vaginal suppository, to prepare the cervix for labour and to induce labour.
Approved
Matched Synonyms: … (5Z,11α,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid ... (Z)-7-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)hept-5-enoic acid ... (E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid
Matched Iupac: … (5Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]hept-5-enoic acid
Matched Description: … As a prescription drug it is used as a vaginal suppository, to prepare the cervix for labour and to induce …
Matched Categories: … Genito Urinary System and Sex Hormones ... Fatty Acids ... Fatty Acids, Unsaturated …
Risdiplam is an orally bioavailable mRNA splicing modifier used for the treatment of spinal muscular atrophy (SMA). It increases systemic SMN protein concentrations by improving the efficiency of SMN2 gene transcription. This mechanism of action is similar to its predecessor nusinersen, the biggest difference being their route of administration: nusinersen...
Approved
Investigational
Matched Description: … substantially cheaper than other available SMA therapies,[L15351] risdiplam appears to provide a novel and ... Risdiplam is an orally bioavailable mRNA splicing modifier used for the treatment of spinal muscular ... relatively accessible treatment option for patients with SMA regardless of severity or type. …
Matched Categories: … Cytochrome P-450 Substrates ... P-glycoprotein substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates ... Cytochrome P-450 CYP3A7 Substrates …
Matched Products: … Evrysdi Powder for oral solution 0.75 mg/mL ... EVRYSDI POWDER FOR ORAL SOLUTION 0.75 MG/ML …
Capromab is a Murine IgG1 monoclonal 7E11-C5.3 antibody that recognizes prostate specific membrane antigen (PSMA – also known as glutamate carboxypeptidase 2) from prostate cancer cells and normal prostate tissue. When linked to pendetide, capromab is used as a chelating agent for the radionuclide Indium In-111 during imaging to evaluate...
Approved
Matched Description: … specific membrane antigen (PSMA – also known as glutamate carboxypeptidase 2) from prostate cancer cells and ... When linked to pendetide, capromab is used as a chelating agent for the radionuclide [Indium In-111] …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Indicators and Reagents …
Matched Products: … ProstaScint Kit for the Preparation of Indium In 111 Capromab Pendetide …
Galsufase is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant DNA origin. Galsulfase is a glycoprotein with a molecular weight of approximately 56 kD. The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation sites, four of which carry a bis mannose-6-phosphate...
Approved
Investigational
Matched Description: … The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation ... which is required for enzyme activity and is conserved in all members of the sulfatase enzyme family. ... sites, four of which carry a bis mannose-6-phosphate manose7 oligosaccharide for specific cellular recognition …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Chondroitinases and Chondroitin Lyases …
Matched Products: … Naglazyme Concentrated Solution for Intravenous Infusion 1mg/1ml …
Approved
Nutraceutical
Matched Mixtures name: … AMINOVEN SOLUTION FOR INFUSION 15% …
Matched Salts name: … L-arginine hydrochloride
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino ... Amino Acids, Essential …
Matched Products: … LYSAKARE SOLUTION FOR INFUSION 25G / 25G …
Technetium 99m sulfur colloid is a radiopharmaceutical diagnostic agent used in the evaluation of various conditions including lymph node metastases in breast cancer, detection of shunt patency, imaging of reticuloendothelial cells for assessment of liver function, and studies of esophageal transit and gastroesophageal reflux. Following injection or oral administration, single...
Approved
Investigational
Matched Description: … assessment of liver function, and studies of esophageal transit and gastroesophageal reflux. ... Depending on site of administration and intended usage, Technetium 99m sulfur colloid enters the capillaries ... and is transported to the lymph nodes (subcutaneous injection), mixes with peritoneal fluid (intraperitoneal …
Matched Categories: … Indicators and Reagents ... Hepatic and Reticulo Endothelial System ... Technetium (99Mtc), Particles and Colloids …
Matched Products: … Kit for the Prepartion of Technetium Tc99m Sulfur Colloid ... Kit for the Preparation of Technetium Tc 99m Sulfur Colloid …
Bacampicillin is a prodrug of ampicillin and is microbiologically inactive. It is absorbed following oral administration. During absorption from the gastrointestinal tract, bacampicillin is hydrolyzed by esterases present in the intestinal wall. It is microbiologically active as ampicillin, and exerts a bactericidal action through the inhibition of the biosynthesis of...
Approved
Investigational
Matched Description: … Bacampicillin is a prodrug of ampicillin and is microbiologically inactive. ... It is used to cure infection of upper and lower respiratory tract; skin and soft tissue; urinary tract ... and acute uncomplicated gonococcal urethritis etc. …
Matched Salts name: … Bacampicillin hydrochloride
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … BAKAMSİLİN FORT 800 MG FİLM TABLET, 10 ADET …
Entinostat is under investigation for the treatment and other of Volunteers, Breast Cancer, Human Volunteers, and Normal Volunteers. Entinostat has been investigated for the treatment of Non-Small Lung Cancer, Epigenetic Therapy.
Investigational
Matched Synonyms: … N-[[4-[(2-aminoanilino)-oxomethyl]phenyl]methyl]carbamic acid 3-pyridinylmethyl ester …
Matched Description: … Entinostat is under investigation for the treatment and other of Volunteers, Breast Cancer, Human Volunteers ... , and Normal Volunteers. ... Entinostat has been investigated for the treatment of Non-Small Lung Cancer, Epigenetic Therapy. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Acids, Carbocyclic ... Carboxylic Acids
PLX51107 is a potent and selective inhibitor of the bromodomain and extraterminal (BET) protein family.[A257246,A257251] PLX51107 is under investigation in clinical trial NCT04022785 (PLX51107 and Azacitidine in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome).
Investigational
Matched Synonyms: … Benzoic acid, 4-(6-(3,5-dimethyl-4-isoxazolyl)-1-((1s)-1-(2-pyridinyl)ethyl)-1h-pyrrolo(3,2-b)pyridin …
Matched Iupac: … 4-[6-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[1-(pyridin-2-yl)ethyl]-1H-pyrrolo[3,2-b]pyridin-3-yl]benzoic acid
Matched Description: … PLX51107 is a potent and selective inhibitor of the bromodomain and extraterminal (BET) protein family ... [A257246,A257251] PLX51107 is under investigation in clinical trial NCT04022785 (PLX51107 and Azacitidine …
Overactive bladder (OAB) is a common condition negatively impacting the lives of millions of patients worldwide. Due to its urinary symptoms that include nocturia, urgency, and frequency, this condition causes social embarrassment and a poor quality of life.[A185996,A185999] Oxybutynin, also marketed as Ditropan XL, is an anticholinergic medication used for...
Approved
Investigational
Matched Synonyms: … 4-(Diethylamino)-2-butynyl alpha-phenylcyclohexaneglycolic acid ester …
Matched Description: … the relief of overactive bladder symptoms that has been optimized for high levels of safety and efficacy ... embarrassment and a poor quality of life. ... Due to its urinary symptoms that include nocturia, urgency, and frequency, this condition causes social …
Matched Categories: … Drugs for Urinary Frequency and Incontinence ... Genito Urinary System and Sex Hormones ... Acids, Carbocyclic ... Carboxylic Acids ... Hydroxy Acids
Matched Products: … Oxytrol For Women ... Oxytrol for Women ... PMS-oxybutynin …
Sotrovimab (VIR-7831), also known as GSK4182136, is a monoclonal antibody that can neutralize the SARS-CoV-2 virus. Sotrovimab was initially been granted emergency use authorization (EUA) to treat mild-to-moderate COVID-19 on May 26, 2021, based on interim results from a clinical trial, where sotrovimab was found to reduce the risk of...
Approved
Investigational
Matched Description: … [L34425, L34430, L34440] However, in April 2022, the FDA removed the EUA for sotrovimab due to the rising …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins ... Antiinfectives for Systemic Use ... Approved Treatments for COVID-19 ... Experimental Unapproved Treatments for COVID-19 …
Matched Products: … Sotrovimab for Injection …
A orally active prolyl-hydroxylase inhibitor which can stabilize hypoxia-inducible transcription factor independent of oxygen availability.
Investigational
Matched Synonyms: … (((1-Chloro-4-hydroxyisoquinolin-3-yl)carbonyl)amino)acetic acid
Matched Iupac: … 2-[(1-chloro-4-hydroxyisoquinolin-3-yl)formamido]acetic acid
Approved
Experimental
Matched Products: … Pulmolite, Kit for the Preparation of Technetium Tc99m Albumin Aggregated …
Approved
Investigational
Matched Mixtures name: … -POLIO SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE ... Tetanus and Diphtheria Toxoids Adsorbed for Adult Use ... Diphtheria and Tetanus Toxoids Adsorbed …
Matched Categories: … Antiinfectives for Systemic Use …
Matched Products: … Diphtheria Toxoid for Reaction Test 0.2lf/ml ... Diphtheria Toxoid for Schick Control 0.2lf/ml …
Edaravone is a free radical scavenger and neuroprotective agent with antioxidant properties. It has three tautomers. Edaravone works to scavenge reactive oxygen species, which have been implicated in neurological disorders, such as amyotrophic lateral sclerosis (ALS) and cerebral ischemia.[A19140,L44007,A254257] The intravenous formulation of edaravone was first approved in Japan in...
Approved
Investigational
Matched Description: … Medicinal Products for Human Use (CHMP) for a long-term study demonstrating the long-term efficacy and ... [L44007] It was later approved for the treatment of amyotrophic lateral sclerosis (ALS) in Japan and ... Edaravone is a free radical scavenger and neuroprotective agent with antioxidant properties. …
Matched Products: … RADICAVA™ IV Concentrate Solution for Infusion 30mg/20mL …
Cytomegalovirus immunoglobulin is obtained from pooled adult human plasma selected for high titers of antibody for cytomegalovirus (CMV). It contains purified immunoglobulin G (IgG) antibodies targeting cytomegalovirus (CMV)[FDA label]. Cytomegalovirus, a member of the herpes virus family, is ubiquitous the human population, leading to infections which are followed by life-long...
Approved
Matched Description: … CMV infection can lead to a high fever and severe organ-specific damage with significant morbidity and ... antibody for cytomegalovirus (CMV). ... vaginal excretions, semen, breast milk and blood [L2228]. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins ... Antiinfectives for Systemic Use …
Matched Products: … MEGALOTECT CP SOLUTION FOR INFUSION 100 U/ML …
Experimental
Matched Name: … (2R)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(9E)-HEXADEC-9-ENOYLOXY]PROPYL (9E …
Matched Iupac: … 2,3-dihydroxypropoxy][(2R)-2-[(9Z)-hexadec-9-enoyloxy]-3-[(9Z)-octadec-9-enoyloxy]propoxy]phosphinic acid
Fomepizole is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. Fomepizole is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites.
Approved
Vet approved
Matched Description: … alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2A6 Inhibitors ... Cytochrome P-450 CYP2E1 Inducers ... Cytochrome P-450 Enzyme Inducers ... Cytochrome P-450 CYP2E1 Inhibitors …
Matched Products: … Fomepizole for Injection …
Displaying drugs 3126 - 3150 of 3888 in total