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Displaying drugs 3151 - 3175 of 3344 in total

Brolucizumab

Brolucizumab, also known as RTH258 or ESBA1008, is a monoclonal antibody indicated to treat neovascular age related macular degeneration. Brolucizumab was granted FDA approval in October 2019.
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Pagenax 120mg/ml Solution For Injection …

Magnesium chloride

Magnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can be extracted from brine or sea water.
Approved
Matched Description: … Magnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can …
Matched Mixtures name: … Dianeal Pd4 Capd Solution With 1.5% Dextrose and 2.5meq/l Calcium ... Dianeal Pd4 Capd Solution With 2.5% Dextrose and 2.5meq/l Calcium ... Dianeal Pd4 Capd Solution With 4.25% Dextrose and 2.5meq/l Calcium …
Matched Categories: … Blood and Blood Forming Organs ... Alimentary Tract and Metabolism ... Blood Substitutes and Perfusion Solutions …
Matched Products: … Magnesium Chloride for Hemodialysis 5.15 …

Levosimendan

Levosimendan increases calcium sensitivity to myocytes by binding to troponin C in a calcium dependent manner. This increases contractility without raising calcium levels. It also relaxes vascular smooth muscle by opening adenosine triphosphate sensitive potassium channels. Levosimendan is used to manage acutely decompensated congestive heart failure.
Approved
Investigational
Matched Description: … Levosimendan increases calcium sensitivity to myocytes by binding to troponin C in a calcium dependent ... This increases contractility without raising calcium levels. …
Matched Products: … SIMDAX 2.5 MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION …

Lipegfilgrastim

Lipegfilgrastim, previously known as XM22, is a pegylated, recombinant granulocyte colony-stimulating factor (G-CSF) that was synthetized using a highly site-specific glycoPEGylation technology . It is used as an alternate to DB00019 for prophylactic use in cancer patients receiving chemotherapy and at risk for developing chemotherapy-induced neutropenia. Since July 2013, lipegfilgrastim...
Approved
Investigational
Matched Description: … Da for glycylsialic acid and approximately 20,000 Da for PEG [L2449]. ... and at risk for developing chemotherapy-induced neutropenia. ... Severe chemotherapy-induced neutropenia and febrile neutropenia significantly increases the risk for …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … LONQUEX SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 6MG/0.6ML …

Sage oil

Sage oil is extracted from sage or Salvia officinalis, the herb commonly used for culinary purposes. Salvia officinalis is a common sage and a member of the genus Salvia, that includes aromatic and perennial plants with flowers. Essential oil has been traditionally used in medicine for the relief of pain...
Nutraceutical
Matched Description: … Essential oil has been traditionally used in medicine for the relief of pain and the treatment of inflammation ... Sage oil is extracted from sage or *Salvia officinalis*, the herb commonly used for culinary purposes ... *Salvia officinalis* is a common sage and a member of the genus *Salvia*, that includes aromatic and …
Matched Products: … Storks Synergy for balance of uterus …

Interferon beta-1b

Human interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD
Approved
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … BETAFERON FOR INJECTION 0.25 mg/ml …

Quinidine

Quinidine is a D-isomer of quinine present in the bark of the Cinchona tree and similar plant species. This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication.[A38016,A250050] Quinidine is considered the first antiarrhythmic drug (class Ia) and is moderately efficacious in the acute...
Approved
Investigational
Matched Description: … Quinidine is a D-isomer of [quinine] present in the bark of the Cinchona tree and similar plant species ... This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication. ... [A38016] It prolongs cellular action potential by blocking sodium and potassium currents. …
Matched Categories: … Quinine and stereoisomer ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … Quinidine Gluconate for Inj 80mg/ml USP …

LM-030

Investigational
Matched Synonyms: … (S)-2-ISOBUTYRYLAMINO-PENTANEDIOIC ACID 5-AMIDE 1-{[(2S,5S,8S,11R,12S,15S,18S,21R)-2,8-BIS-((S)-SEC-BUTYL …

Hepatitis A Vaccine

Hepatitis A viral infection can lead to significant morbidity and mortality, with signs and symptoms that include anorexia, nausea, vomiting, and liver failure. Known by several trade names, such as Havrix and Twinrix, the Hepatitis A vaccine has been formulated for immunization against hepatitis A virus (HAV) infection and safely...
Approved
Matched Description: … formulated for immunization against hepatitis A virus (HAV) infection and safely confers strong protection ... Hepatitis A viral infection can lead to significant morbidity and mortality, with signs and symptoms ... that include anorexia, nausea, vomiting, and liver failure. …
Matched Products: … AVAXIM 80U PEDIATRIC SUSPENSION FOR INJECTION ... AVAXIM-SUSPENSION FOR INJ IN A PREFILLED SYRINGE ... AVAXIM 80U PEDIATRIC, SUSPENSION FOR INJECTION IN PREFILLED SYRINGE, 80U/0.5ml …

Olive oil

Oil extracted from olives . Consists primarily of the glycerides of the fatty acids linoleic, oleic and palmitic. Used as a source of fatty acids in total parenteral nutrition and as an additive in some cosmetic products [FDA Label].
Approved
Matched Description: … Consists primarily of the glycerides of the fatty acids linoleic, oleic and palmitic. ... Used as a source of fatty acids in total parenteral nutrition and as an additive in some cosmetic products …
Matched Mixtures name: … SmofKabiven, Emulsion for Infusion ... OLIMEL N7E, emulsion for infusion ... OLIMEL N9E, emulsion for infusion …
Matched Categories: … Diet, Food, and Nutrition …
Matched Products: … Intensive Treatment Bodyoil for Mommy To Be All Skin …

Mebrofenin

Approved
Experimental
Matched Iupac: … 2-({[(3-bromo-2,4,6-trimethylphenyl)carbamoyl]methyl}(carboxymethyl)amino)acetic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Matched Products: … Kit for the Preparation of Technetium Tc 99m Mebrofenin …

4-{4-[2-(1A,7A-DIMETHYL-4-OXY-OCTAHYDRO-1-OXA-4-AZA-CYCLOPROPA[A]NAPHTHALEN-4-YL) -ACETYLAMINO]-PHENYLCARBAMOYL}-BUTYRIC ACID

Experimental
Matched Name: … 7A-DIMETHYL-4-OXY-OCTAHYDRO-1-OXA-4-AZA-CYCLOPROPA[A]NAPHTHALEN-4-YL) -ACETYLAMINO]-PHENYLCARBAMOYL}-BUTYRIC ACID …

Hydroxocobalamin

Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B 12 that has been used therapeutically to treat vitamin B 12 deficiency. It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia.
Approved
Matched Iupac: … undecamethyl-15,20-dioxo-11,14,16-trioxa-2lambda5,9,19,26,43lambda5,44lambda5,45lambda5-heptaaza-15lambda5-phospha …
Matched Description: … Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B ... It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia. …
Matched Mixtures name: … FORVIN …
Matched Categories: … Vitamin B12 and Folic Acid ... Blood and Blood Forming Organs …
Matched Products: … HYDROXO-B12 SOLUTION FOR INJECTION 1MG/1ML …

Ephedrine

Ephedrine was first described in western literature in 1888, as a naturally occurring component of the ephedra plant, along with pseudoephedrine. Ephedrine acts as both a direct and indirect sympathomimetic. It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of norepinephrine from sympathetic neurons,...
Approved
Matched Description: … [A193650,L12972] Ephedrine is used for its vasoconstrictive, positive chronotropic, and positive inotropic ... [A193698] Ephedrine acts as both a direct and indirect sympathomimetic. ... It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of …
Matched Mixtures name: … UNISEDYL FORTE LINCTUS ... COUGHLAX FORTE SYRUP ... SUNSEDYL FORTE COUGH LINCTUS …
Matched Categories: … Adrenergics for Systemic Use ... Adrenergic and Dopaminergic Agents ... Drugs for Obstructive Airway Diseases ... Alimentary Tract and Metabolism ... Alpha-and Beta-adrenergic Agonists …
Matched Products: … EPHEDRINE AGUETTANT SOLUTION FOR INJECTION 30MG/ML ... MARTINDALE PHARMA EPHEDRINE HYDROCHLORIDE SOLUTION FOR INJECTION 30MG/ML …

{4-[(2s,4e)-2-(1,3-Benzothiazol-2-Yl)-2-(1h-1,2,3-Benzotriazol-1-Yl)-5-Phenylpent-4-Enyl]Phenyl}(Difluoro)Methylphosphonic Acid

Experimental
Matched Name: … Benzothiazol-2-Yl)-2-(1h-1,2,3-Benzotriazol-1-Yl)-5-Phenylpent-4-Enyl]Phenyl}(Difluoro)Methylphosphonic Acid …
Matched Iupac: … benzothiazol-2-yl)-2-(1H-1,2,3-benzotriazol-1-yl)-5-phenylpent-4-en-1-yl]phenyl}difluoromethyl)phosphonic acid …

2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-3-METHYL-BUTYRIC ACID

Experimental
Matched Name: … 2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-3-METHYL-BUTYRIC ACID …
Matched Iupac: … [4-(2-{2-amino-4-oxo-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}ethyl)phenyl]formamido}-3-methylbutanoic acid …

Rabies virus inactivated antigen, B

Inactivated rabies virus antigen B is a component of rabies vaccines used for pre- and post-exposure prophylaxis against rabies.
Approved
Matched Description: … Inactivated rabies virus antigen B is a component of rabies vaccines used for pre- and post-exposure …
Matched Categories: … Immune Sera and Immunoglobulins ... Antiinfectives for Systemic Use …
Matched Products: … RABIES VACCINE FOR HUMAN USE (VERO CELL), FREEZE-DRIED FINAL BULK …

Lecithin, soybean

A complex mixture of phospholipids; glycolipids; and triglycerides; with substantial amounts of phosphatidylcholines; phosphatidylethanolamines; and phosphatidylinositols, which are sometimes loosely termed as 1,2-diacyl-3-phosphocholines. Lecithin is a component of the cell membrane and commercially extracted from soybeans and egg yolk. The emulsifying and surfactant properties are useful in food additives and...
Experimental
Matched Description: … The emulsifying and surfactant properties are useful in food additives and for forming organogels (gels ... Lecithin is a component of the cell membrane and commercially extracted from soybeans and egg yolk. ... A complex mixture of phospholipids; glycolipids; and triglycerides; with substantial amounts of phosphatidylcholines …
Matched Products: … Essentiale Forte N ... ESSENTIALE FORTE 300 MG ... Essentiale forte - Kapseln …

Linezolid

Linezolid is a synthetic antibiotic which is used for the treatment of infections caused by aerobic Gram-positive bacteria. Its effects are bacteriostatic against both enterococci and staphylococci and bactericidal against most isolates of streptococci. Linezolid exerts its antibacterial activity by inhibiting the initiation of bacterial protein synthesis - more specifically,...
Approved
Investigational
Matched Description: … Its effects are bacteriostatic against both enterococci and staphylococci and bactericidal against most ... generally more effective and tolerable than its predecessor. ... synthesis - more specifically, it binds to the 23S ribosomal RNA of the 50S subunit[A11227,A199050] and …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Products: … ZYVOX SOLUTION FOR INFUSION 2 mg/ml ... CINEZOLID solution for infusion 2mg/mL ... ZYVOX 20MG/ML GRANULES FOR ORAL SUSPENSION …

Vecuronium

Monoquaternary homolog of pancuronium. A non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. Its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination as well as its short duration of action and easy reversibility provide advantages over, or alternatives to, other...
Approved
Investigational
Matched Description: … Its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination ... as well as its short duration of action and easy reversibility provide advantages over, or alternatives …
Matched Products: … Vecuronium Bromide for Injection ... VECURONIUM BROMIDE FOR INJECTION …

Human Rho(D) immune globulin

Human Rho(D) immune globulin is a medicine given by intramuscular or intravenous injection that is used to prevent the immunological condition known as Rh disease (or hemolytic disease of newborn). Rho (D) immune globulin is available as a sterile, lyophilized or liquid gamma globulin (IgG) fraction containing antibodies to the...
Approved
Investigational
Matched Description: … Immune globullin was purified via ion-exchange chromatography method and prepared from pools of human ... It was approved by FDA as treatment for suppression of rhesus (Rh) isoimmunization or chronic immune …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins ... Antiinfectives for Systemic Use …
Matched Products: … RHESONATIV 625 IU/ML SOLUTION FOR INJECTION ... rhophylac 300 microgram/2ml,solution for injection in pre-filled syringe …

Benzatropine

Benztropine, with the chemical formula 3alpha-diphenylmethoxytropane, is a tropane-based dopamine inhibitor used for the symptomatic treatment of Parkinson's disease. It is a combination molecule between a tropane ring, similar to cocaine, and a diphenyl ether from the dialkylpiperazines determined to be a dopamine uptake inhibitor since 1970. The generation of...
Approved
Matched Description: … It is a combination molecule between a tropane ring, similar to cocaine, and a diphenyl ether from the ... dopamine uptake inhibition as well as a decreased inhibition of serotonin and norepinephrine. ... [A37914] Benztropine was developed by USL Pharma and officially approved by the FDA on 1996.[L5500] …
Matched Products: … BENZATROPINE PHEBRA SOLUTION FOR INJECTION 2 MG/2 ML …

Nitroprusside

Nitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles and venules (venules more than arterioles). Nitroprusside is often administered intravenously to patients who are experiencing a hypertensive emergency.
Approved
Investigational
Matched Description: … Nitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles and …
Matched Categories: … Indicators and Reagents ... Nitrates and Nitrites …
Matched Products: … Sodium Nitroprusside for Injection …

Cocoa butter

Cocoa butter is an edible natural fat obtained from the Theobroma cocoa seeds that is predominantly found in dark chocolate . It is a rich source of monounsaturated and saturated fatty acids that mainly contains approximately 33% DB04224, 25% DB03796, and 33% DB03193 but does not contain caffeine or theobromine....
Approved
Matched Description: … skin products such as lotions, creams, and bars intended to maintain skin softness. ... It is a rich source of monounsaturated and saturated fatty acids [A33040] that mainly contains approximately ... The lipid-lowering effects of cocoa butter have been studied and investigated, as fatty acid constituents …
Matched Mixtures name: … Up and Up Hemorrhoidal ... Avedana Hemorrhoidal …
Matched Categories: … Antipruritics and Local Anesthetics ... Diet, Food, and Nutrition …
Matched Products: … Dermatitica Synergy for treatment of Dermatitis …

Inobrodib

Investigational
Matched Synonyms: … (s)-1-(3,4-difluorophenyl)-6-(5-(3,5-dimethylisoxazol-4-yl)-1-((1r,4s)-4-methoxycyclohexyl)-1h-benzo( …
Displaying drugs 3151 - 3175 of 3344 in total