Search Results | DrugBank Online

Displaying drugs 3201 - 3225 of 9612 in total

LX-7101

LX-7101 is under investigation in clinical trial NCT01528111 (Study to Evaluate the Safety, Tolerability, and Efficacy of LX7101 in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension).

Investigational

Matched Iupac: … 3-[4-(aminomethyl)-1-{5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl}piperidine-4-amido]phenyl N,N-dimethylcarbamate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

7beta-hydroxycholesterol

Experimental

Matched Iupac: … (1R,3aS,3bS,4R,7S,9aR,9bS,11aR)-9a,11a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-1H,2H,3H,3aH,3bH,4H,6H,7H …

Zofin, previously known as Organicell Flow, is a nanoparticle-based therapeutic derived from perinatal sources which is manufactured in a way that retains the naturally occurring microRNAs without the addition of other substances .

Investigational

Ochromycinone

Ochromycinone is under investigation in clinical trial NCT01047943 (STA-21 Topical Efficacy on Psoriasis).

Investigational

Matched Synonyms: … Benz(a)anthracene-1,7,12(2h)-trione, 3,4-dihydro-8-hydroxy-3-methyl-, (s)- ... (3s)-3.beta.-methyl-8-hydroxy-1,2,3,4,7,12-hexahydrobenzo(a)anthracene-1,7,12-trione …
Matched Iupac: … (3S)-8-hydroxy-3-methyl-1,2,3,4,7,12-hexahydrotetraphene-1,7,12-trione …

Lintuzumab satetraxetan AC-225

Lintuzumab actinium Ac-225 is under investigation in clinical trial NCT00672165 (Targeted Atomic Nano-Generators (Actinium-225-Labeled Humanized Anti-CD33 Monoclonal Antibody HuM195) in Patients With Advanced Myeloid Malignancies).

Investigational

Freneslerbart

Freneslerbart is under investigation in clinical trial NCT04981717 (A Study to Examine the Efficacy and Safety of Anti-fel D 1 Antibodies Injections in Cat-allergic Adolescent and Adult Patients With Allergic Rhinitis Who Live With a Cat).

Investigational

Matched Synonyms: … Anti-cat allergen fel d 1 monoclonal anitbody regn-1908 …
Matched Description: … investigation in clinical trial NCT04981717 (A Study to Examine the Efficacy and Safety of Anti-fel D 1 …

Nelonicline

Nelonicline is under investigation in clinical trial NCT01678755 (A Phase 2 Study to Evaluate ABT-126 for the Treatment of Cognitive Deficits in Schizophrenia).

Investigational

Matched Synonyms: … 2-((3r,4s,5s,7s)-1-azaadamantan-4-yloxy)-5-phenyl-1,3,4-thiadiazole, rel- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Tovinontrine

Tovinontrine is an orally administered, highly selective phosphodiesterase 9 (PDE9) small molecule inhibitor. Tovinontrine is under investigation in clinical trial NCT04474314 (A Study of IMR-687 in Subjects With Sickle Cell Disease).

Investigational

Matched Synonyms: … 6-((3S,4S)-4-METHYL-1-(2-PYRIMIDINYLMETHYL)-3-PYRROLIDINYL)-3-(TETRAHYDRO-2H-PYRAN-4-YL)IMIDAZO(1,5-A ... 6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-3- tetrahydropyran-4-yl-7H-imidazo[1,5-a ... 6-[(3S,4S-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-3-tetrahydropyran-4-yl-7H-imadazo[1,5-a]pyrazin …
Matched Iupac: … 6-[(3S,4S)-4-methyl-1-[(pyrimidin-2-yl)methyl]pyrrolidin-3-yl]-3-(oxan-4-yl)-7H,8H-imidazo[1,5-a]pyrazin …

Arbaclofen Placarbil

Arbaclofen Placerbil is a prodrug of Arbaclofen, which is a selective gamma-amino-butyric acid type B receptor agonist and the R-enantiomer of baclofen. It was discovered, and has been patented by XenoPort as a new chemical entity with an improved pharmacokinetic profile compared to baclofen, which allows for sustained release properties....

Investigational

Matched Iupac: … (3R)-3-(4-chlorophenyl)-4-({[(1S)-2-methyl-1-[(2-methylpropanoyl)oxy]propoxy]carbonyl}amino)butanoic …

SEL120-34A free base

Investigational

Matched Synonyms: … 4h-imidazo(4,5,1-ij)quinoline, 7,8-dibromo-5,6-dihydro-9-methyl-2-(1-piperazinyl)- ... 7,8-DIBROMO-5,6-DIHYDRO-9-METHYL-2-(1-PIPERAZINYL)-4H-IMIDAZO(4,5,1-IJ)QUINOLINE …
Matched Iupac: … 6,7-dibromo-5-methyl-2-(piperazin-1-yl)-1,3-diazatricyclo[6.3.1.0^{4,12}]dodeca-2,4,6,8(12)-tetraene …
Matched Salts cas: … 1609452-30-3 …

Tigilanol tiglate

Investigational

Matched Synonyms: … 12-tigloyl-13-(2-methylbutanoyl)-6,7-epoxy-4,5,9,12,13,20-hexahydroxy-1-tiglian-3-one ... tigliaen-3-one ... ,13s,14r)-12-(2e)-2-methyl-2-enoatyl-13((2s)-2-methylbutyroyl)-6,7-epoxy-4,5,9,12,13,20-hexahydroxy-1- …

3,7,11,15-tetramethyl-hexadecan-1-ol

Experimental

Investigational

Matched Name: … 3,7,11,15-tetramethyl-hexadecan-1-ol …
Matched Iupac: … (3S,7S,11S)-3,7,11,15-tetramethylhexadecan-1-ol …

Gusperimus

Gusperimus has been used in trials studying the treatment of Lupus Nephritis, Wegeners Granulomatosis, and Wegener's Granulomatosis.

Investigational

Matched Iupac: … N-[({4-[(3-aminopropyl)amino]butyl}carbamoyl)(hydroxy)methyl]-7-carbamimidamidoheptanamide …

Ad5-nCoV

Ad5-nCoV is a recombinant adenovirus type-5 vector (Ad5) vaccine currently being investigated for prophylaxis against SARS-CoV-2.[L12675,L12678] It is being developed by CanSino Biologics Inc., in partnership with the Beijing Institute of Biotechnology, who in March 2020 announced the approval of a phase I clinical trial (ChiCTR2000030906) with an expected completion...

Investigational

Matched Description: … who will receive one of three study doses, with follow-up taking place at weeks 2 and 4 and months 3 …
Matched Categories: … Experimental Unapproved Treatments for COVID-19 …

BNT162a1 SARS-CoV-2 Vaccine

BNT162a1 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002, L15007] BNT162a1 is a uridine mRNA (uRNA) vaccine formulated in lipid nanoparticles for delivery via intramuscular injection.[L15002, L15007] BNT162a1 is undergoing evaluation in clinical trials in both the USA (NCT04368728)...

Investigational