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Displaying drugs 301 - 325 of 10641 in total

Dihydroergocristine

Dihydroergocristine is part of the ergoloid mixture products. It is a semisynthetic ergot alkaloid and thus, it is characterized by a structural skeleton formed by an alkaloid ergoline. To know more about ergoloid mixtures, please visit DB01049.
Approved
Experimental
Matched Iupac: … diazatricyclo[7.3.0.0^{2,6}]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1( …

Relatlimab

Relatlimab is a human IgG4 monoclonal antibody and novel immune checkpoint inhibitor that targets lymphocyte activation gene-3 (LAG-3).[A246165,L41265] It was the first commercially developed anti-LAG-3 antibody, entering clinical trials in 2013, and has garnered interest in the treatment of a variety of cancers, including leukemia and melanoma. As immune checkpoint...
Approved
Investigational
Matched Description: … like relatlimab have been trialed in combination with other checkpoint inhibitors - for example, PD-1 ... [A246155] Relatlimab received FDA approval in March 2022, alongside the PD-1 inhibitor [nivolumab] …

Hexylresorcinol

Hexylresorcinol is a substituted dihydroxybenzene. It exhibits antiseptic, anthelmintic, and local anesthetic properties. It can be found in topical applications for minor skin infections and in oral solutions or throat lozenges for pain relief and first aid antiseptic. The compound may also be used commonly in various commercial cosmetic anti-aging...
Approved

Lincomycin

Lincomycin is a lincosamide antibiotic first isolated from the soil bacterium Streptomyces lincolnensis in Lincoln, Nebraska. Clinical use of lincomycin has largely been superseded by its semisynthetic derivative clindamycin due to its higher efficacy and a wider range of susceptible organisms, though lincomycin remains in use.[A190657, A190621] Lincomycin was approved...
Approved
Vet approved
Matched Iupac: … -1-methyl-4-propylpyrrolidine-2-carboxamide ... (2S,4R)-N-[(1R,2R)-2-hydroxy-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl] …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … LINCO-NOBEL AMPUL, 1 ADET ... LINKOMED 600 MG 1 AMPUL ... LINKOMISIN İE AMPUL, 1 ADET …

Tolterodine

Tolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.
Approved
Investigational
Matched Iupac: … 2-[(1R)-3-[bis(propan-2-yl)amino]-1-phenylpropyl]-4-methylphenol …
Matched Products: … URIONE TABLETAS 1 MG ... DETRUSITOL TABLET 1 mg ... TOLTEX 1 MG 56 FILMTABLET …

Enfuvirtide

Enfuvirtide is a 36 amino acid biomimetic peptide that is structurally similar to the HIV proteins that are responsible for the fusion of the virus to cell membranes and subsequent intracellular uptake. The first agent in the novel class of antiretroviral drugs called HIV fusion inhibitors, enfuvirtide works by inhibiting...
Approved
Investigational
Matched Description: … novel class of antiretroviral drugs called HIV fusion inhibitors, enfuvirtide works by inhibiting HIV-1 …
Matched Categories: … Human Immunodeficiency Virus 1 Fusion Inhibitor …

Vancomycin

Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear. As of January 29 2018, CutisPharma's Firvanq is the only FDA approved vancomycin oral liquid treatment option available for the the treatment of...
Approved
Matched Iupac: … pentanamido]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2^{3,6}.2^{14,17}.1^ ... {8,12}.1^{29,33}.0^{10,25}.0^{34,39}]pentaconta-3,5,8,10,12(48),14,16,29(45),30,32,34,36,38,46,49-pentadecaene …
Matched Products: … VANKOMISIN HCL DBL 1 GR FLAKON, 1 ADET ... PMS-vancomycin 1 G ... EDICIN 1 G IV INFÜZYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 1 ADET …

Etoposide

A semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division,...
Approved
Matched Iupac: … hydroxy-3,5-dimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1,3(7),8-trien-12 …
Matched Products: … ICEREN FLAKON, 1 ADET ... LASTET 100 MG ENJEKTABL, 1 ADET ... INFUZYON COZELTISI ICEREN FLAKON, 1 ADET …

Canakinumab

Canakinumab is a recombinant, human anti-human-IL-1β monoclonal antibody that belongs to the IgG1/κ isotype subclass. It is expressed in a murine Sp2/0-Ag14 cell line and comprised of two 447- (or 448-) residue heavy chains and two 214-residue light chains, with a molecular mass of 145157 Daltons when deglycosylated. Both heavy...
Approved
Investigational
Matched Description: … receptors, but it does not bind IL-1alpha or IL-1 receptor antagonist (IL-1ra). ... binds to human IL-1β and neutralizes its inflammatory activity by blocking its interaction with IL-1 ... safe and effective, offering a considerable advantage over the existing treatment with the human IL-1 …
Matched Categories: … Interleukin-1 Blockers …
Matched Products: … İLARİS 150 MG/ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... ILARIS 150 MG/ML ENJEKSIYONLUK COZELTI ICIN TOZ ICEREN FLAKON, 1 ADET ... IBECTA 150 MG/ML SC ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ İÇEREN FLAKON, 1 ADET …

Testosterone

Testosterone is a steroid sex hormone indicated to treat primary hypogonadism and hypogonadotropic hypogonadism.[L8983,L8935,L8938,L8986,L8989,L8992,L8995] Testosterone antagonizes the androgen receptor to induce gene expression that causes the growth and development of masculine sex organs and secondary sexual characteristics.[A187114,L8983,L8935,L8938,L8986,L8989,L8992,L8995] Testosterone was isolated from samples and also synthesized in 1935.
Approved
Investigational
Matched Iupac: … (1S,3aS,3bR,9aR,9bS,11aS)-1-hydroxy-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta …
Matched Products: … Testim 1% ... Testosterone Gel, 1% ... ANDROGEL ® 1% GEL …

Aminosalicylic acid

An antitubercular agent often administered in association with isoniazid. The sodium salt of the drug is better tolerated than the free acid.
Approved
Matched Salts cas: … 6059-16-1 …
Matched Products: … เอส-เอ-เอส-1 ... PAS 1 G TABLET, 250 ADET ... PAS 1 G TABLET , 5000 ADET …

Trabectedin

Trabectedin, also referred as ET-743 during its development, is a marine-derived antitumor agent discovered in the Carribean tunicate Ecteinascidia turbinata and now produced synthetically. Trabectedin has a unique mechanism of action. It binds to the minor groove of DNA interfering with cell division and genetic transcription processes and DNA repair...
Approved
Investigational
Matched Iupac: … (1R,2R,3R,11S,12S,14R,26R)-5,6',12-trihydroxy-6,7'-dimethoxy-7,21,30-trimethyl-27-oxo-3',4'-dihydro-2 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … YONDELIS 1 MG IV KONSANTRE INFUZYONLUK COZELTI ICIN TOZ ... Trabectedin TEVA 1 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung ... Trabectedin SUN 1 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung …

Tetrakis(2-methoxyisobutylisocyanide)copper(I) tetrafluoroborate

Tetrakis (2-methoxyisobutylisocyanide) copper (I) tetrafluoroborate is a component of Cardiolite, a technetium Tc99m-based imaging agent used for assessing myocardial perfusion.
Approved
Matched Iupac: … lambda1-copper(1+) tetrakis(1-isocyano-2-methoxy-2-methylpropane) tetrafluoroboranuide …
Matched Products: … MIBITEC 1 mg Kit für ein radioaktives Arzneimittel ... STAMICIS 1 mg Kit für ein radioaktives Arzneimittel ... CardioTOP 1 mg Kit für ein radioaktives Arzneimittel …

Xylometazoline

Xylometazoline is an imidazoline derivative with sympathomimetic and nasal decongestant activity. Xylometazoline works by binding to alpha (α)-adrenergic receptors to cause vasoconstriction of nasal blood vessels. Xylometazoline is available in over-the-counter (OTC) nasal sprays or drops to temporarily relieve nasal congestion due to cold, hay fever or other respiratory allergies....
Approved
Investigational
Matched Mixtures name: … NASOWELL 1 MG/ML+ 50 MG/ML BURUN SPREYİ, ÇÖZELTİ, 1 ADET ... Otrivin plus Dexpanthenol 1 mg/ml + 50 mg/ml Nasenspray, Lösung ... NASOVİNE DUO 0,5 MG + 0,6 MG/ML BURUN SPREYİ, ÇÖZELTİ, 1 ADET …
Matched Categories: … Adrenergic alpha-1 Receptor Agonists ... Heterocyclic Compounds, 1-Ring …
Matched Products: … NAZE % 0.1 BURUN SPREYI, 1 ADET ... Certified Decongestant Nasal Spray .1% ... easynasan 1 mg/ml Nasenspray, Lösung …

Mesalazine

An anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory drugs like acetylsalicylic acid, which is active in inflammatory bowel disease . Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stability as a pharmaceutical...
Approved
Matched Products: … JARD-1 ... SALOFALK 1 G ... PENTASA (ENEMA) 1 G …

Iophendylate

Iophendylate is a mixture of isomers used as contrast medium, mainly for brain and spinal cord visualization. Iophendylate is a myelographic oil-ester (U.S. Patent 2,348,231). Iophendylate, which was never shown to be safe, was initially introduced for use in small amounts (1-2cc) for locating spinal tumors. It next appeared on...
Approved
Matched Description: … Iophendylate, which was never shown to be safe, was initially introduced for use in small amounts (1- ... It next appeared on the world scene for high volume (12-15cc), routine use, in diagnosing disc herniations …

Lebrikizumab

Lebrikizumab is a monoclonal antibody against IL-13 that binds to a different epitope compared tralokinumab.[A262874,A262879] On November 17, 2023, lebrikizumab was approved by the EMA under the brand name EBGLYSS for the treatment of moderate-to-severe atopic dermatitis in adult and adolescent patients 12 years and older with a body weight...
Approved
Investigational
Matched Description: … EBGLYSS for the treatment of moderate-to-severe atopic dermatitis in adult and adolescent patients 12 ... This approval is based on the positive results obtained from the Phase 3 studies ADvocate 1 and ADvocate …

Gallium citrate Ga-67

Gallium citrate Ga 67 is the citrate salt of the radioisotope gallium Ga 67. Although the mechanism is unknown, gallium Ga 67 concentrates in lysosomes and is bound to a soluble intracellular protein in certain viable primary and metastatic tumors and focal sites of inflammation, allowing scintigraphic localization. Ga-67 scintigraphy...
Approved
Matched Products: … GA - 67 MM-1 ... MON.GALYUM-67 74 MBQ/ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET (5 ML) ... MON.GALYUM-67 74 MBQ/ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET (2.5 ML) …

Lactic acid

A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste. It is produced by fermentation of a sugar source, such as...
Approved
Vet approved
Matched Mixtures name: … DIANEAL PD-1 with Dextrose ... DIANEAL PD-1 with Dextrose ... DIANEAL PD-1 with Dextrose …
Matched Products: … 1/6 MOLAR SODYUM LAKTAT 500 ML SOLUSYON SETLI SISE ... 1/6 MOLAR SODYUM LAKTAT 1000 ML SOLUSYON SETLI SISE ... 1/6 MOLAR SODYUM LAKTAT 500 ML SOLUSYON SETSIZ SISE …

Ergoloid mesylate

Ergoloid Mesylate is an equiproportional preparation of three different ergotamantriones: dihydroergocornine, dihydroergocristine, and dihydroergocryptine. All these components are produced by the fungus Claviceps purpurea and are all derivatives of the tetracyclic compound 6-methylergonovine. The derivatives of this fungus are identified to be about 350 different substances from which the components...
Approved
Matched Products: … อินเดอร์จิน 1 มก. ... นิวโรจีน 1 มิลลิกรัม ... SEGOL 1 MG/ML DAMLA, ÇÖZELTİ, 50 ML …

Gentamicin

Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from Micromonospora purpurea in 1963. It is one of the most frequently prescribed aminoglycosides due to its spectrum of activity, low cost, and availability.[A234339,A234354] Gentamicin is effective against both gram-positive and gram-negative organisms but is particularly useful for the treatment...
Approved
Vet approved
Matched Iupac: … (2R,3R,4R,5R)-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,6S)-3-amino-6-(1-aminoethyl)oxan-2-yl]oxy}- ... methylamino)oxane-3,5-diol; (2R,3R,4R,5R)-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,6S)-3-amino-6-[1- …
Matched Products: … GENTAMICINA40 MG/ 1 ML ... GENTAMED 20 MG 1 AMPUL ... GENTAMED 40 MG 1 AMPUL …

Streptomycin

Streptomycin, an antibiotic derived from Streptomyces griseus, was the first aminoglycoside to be discovered and used in practice in the 1940s.[A233325,A233390] Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in Medicine for their discovery of streptomycin and its antibacterial activity.[A233325,A232294] Although streptomycin was the first antibiotic...
Approved
Vet approved
Matched Products: … STREPTOMYCIN SULFATE FOR INJECTION 1 g/vial ... STREPTOMYCIN SULFAT ENJEKTABL FLAKON, 1 ADET ... KRİSTALİZE STREPTOMİSİN SÜLFAT 1 G ENJEKSİYONLUK ÇÖZELTİ TOZU, 50 ADET …

Brinzolamide

Brinzolamide is a highly specific, non-competitive, reversible carbonic anhydrase II (CA-II) inhibitor indicated to reduce ocular pressure in patients with ocular hypertension or open-angle glaucoma. Although the exact pathophysiology of glaucoma is still unknown, one of the main hallmarks of this disease is vascular dysregulation and abnormalities.[A2049,A2051] The resulting vascular...
Approved
Matched Mixtures name: … BRİTİL-T 10 MG/ML + 5 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 1 ADET …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … BRİTİL %1 GÖZ DAMLASI ... AZOPT OPHTHALMIC SUSPENSION 1% ... BRINZOPT 10 MG/ML GÖZ DAMLASI SÜSPANSIYONU, 1 ADET …

Leucovorin

Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin) is the 5-formyl derivative of tetrahydrofolic acid, a necessary co-factor in the body. Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the...
Approved
Matched Description: … Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary …
Matched Products: … SOLUSYON 1 AMPUL ... ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... ENJEKSİYONLUK ÇÖZELTİ, 1 ADET …

Somatostatin

Somatostatin, also known as growth hormone-inhibiting hormone, is a naturally-occurring peptide hormone of 14 or 28 amino acid residues that regulates the endocrine system. It is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also generated in the hypothalamus, where...
Approved
Investigational
Matched Iupac: … aminobutyl)-37-{2-[(2S)-2-aminopropanamido]acetamido}-13,25,28-tribenzyl-31-(carbamoylmethyl)-10,16-bis[(1R)-1- …
Matched Salts cas: … 54472-66-1 …
Matched Products: … İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 FLAKON + 1 ÇÖZÜCÜ AMPUL ... SOMATOSAN 3 MG IV INFUZYON ICIN 1 AMPUL ... SOMATOSTATIN EUMEDICA 250 MCG IV INFÜZYON ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET …
Displaying drugs 301 - 325 of 10641 in total