Displaying drugs 3301 - 3325 of 3973 in total
Cyclobenzaprine
Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961 and has been available for human use since 1977. It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from Amitriptyline by only a single double bond.[A185039,A184982] Since its approval, it has...
Approved
Matched Synonyms: … (3-Dibenzo[a,d]cyclohepten-5-ylidene-propyl)-dimethyl-amine ... N,N-dimethyl-5H-dibenzo(a,d)cycloheptene-Δ5,γ-propylamine …
Matched Description: … Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961[A185039] and has been …
Matched Salts name: … Cyclobenzaprine hydrochloride …
Matched Products: … Dom-cyclobenzaprine ... Cyclobenzaprine Hydrochloride ... Cyclobenzaprine hydrochloride …
Matched Description: … Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961[A185039] and has been …
Matched Salts name: … Cyclobenzaprine hydrochloride …
Matched Products: … Dom-cyclobenzaprine ... Cyclobenzaprine Hydrochloride ... Cyclobenzaprine hydrochloride …
Medroxyprogesterone acetate
Medroxyprogesterone acetate (MPA) is a progesterone derivative that is more resistant to metabolism for improved pharmacokinetic properties. MPA can be use to treat secondary amenorrhea, endometrial hyperplasia, abnormal uterine bleeding, osteoporosis, vasomotor symptoms in menopause, vulvar and vaginal atrophy, prevent pregnancy, manage pain in endometriosis, prevent pregnancy, and is also...
Approved
Investigational
Matched Synonyms: … 6-alpha-Methyl-17-alpha-acetoxyprogesterone ... 6-alpha-Methyl-17-alpha-hydroxyprogesterone acetate …
Matched Description: … in palliative care for endometrial and renal carcinoma. ... endometrial hyperplasia, abnormal uterine bleeding, osteoporosis, vasomotor symptoms in menopause, vulvar and ... vaginal atrophy, prevent pregnancy, manage pain in endometriosis, prevent pregnancy, and is also used …
Matched Categories: … Corpus Luteum Hormones ... Antineoplastic and Immunomodulating Agents ... Combination Contraceptives (with Estrogen and derivatives) ... Hormones and Related Agents ... Genito Urinary System and Sex Hormones …
Matched Products: … Dom-medroxyprogesterone ... ACETATO DE MEDROXIPROGESTERONA SUSPENSION INYECTABLE 150MG …
Matched Description: … in palliative care for endometrial and renal carcinoma. ... endometrial hyperplasia, abnormal uterine bleeding, osteoporosis, vasomotor symptoms in menopause, vulvar and ... vaginal atrophy, prevent pregnancy, manage pain in endometriosis, prevent pregnancy, and is also used …
Matched Categories: … Corpus Luteum Hormones ... Antineoplastic and Immunomodulating Agents ... Combination Contraceptives (with Estrogen and derivatives) ... Hormones and Related Agents ... Genito Urinary System and Sex Hormones …
Matched Products: … Dom-medroxyprogesterone ... ACETATO DE MEDROXIPROGESTERONA SUSPENSION INYECTABLE 150MG …
BMSC-0013
Experimental
Matched Synonyms: … N-{6-[(Methoxycarbonyl)amino]hexanoyl}-β-D-galactopyranosylamine …
Finasteride
Finasteride is a synthetic 4-azasteroid compound and specific inhibitor of steroid Type II 5α-reductase, which is an intracellular enzyme that converts the androgen testosterone into 5α-dihydrotestosterone (DHT). It works in a similar fashion as dutasteride, which is another 5-alpha-reductase inhibitor, by exerting antiandrogenic effects. Finasteride is an orally active drug...
Approved
Matched Description: … [A178159] In the treatment of benign prostate hyperplasia, alpha-blockers such as [tamsulosin] and [terazosin ... Finasteride is a synthetic 4-azasteroid compound [L10565] and specific inhibitor of steroid Type II 5α-reductase ... by _in situ_ high levels of DHT. …
Matched Categories: … 5-alpha Reductase Inhibitors ... Adrenergic alpha-Antagonists ... Genito Urinary System and Sex Hormones ... Skin and Mucous Membrane Agents ... doxazosin and finasteride …
Matched Products: … FOLIX 1 MG TABLETAS ... Dom-finasteride ... FINASTERIDE DOC …
Matched Categories: … 5-alpha Reductase Inhibitors ... Adrenergic alpha-Antagonists ... Genito Urinary System and Sex Hormones ... Skin and Mucous Membrane Agents ... doxazosin and finasteride …
Matched Products: … FOLIX 1 MG TABLETAS ... Dom-finasteride ... FINASTERIDE DOC …
{[2-(1h-1,2,3-Benzotriazol-1-Yl)-2-(3,4-Difluorophenyl)Propane-1,3-Diyl]Bis[4,1-Phenylene(Difluoromethylene)]}Bis(Phosphonic Acid)
Experimental
Matched Name: … Benzotriazol-1-Yl)-2-(3,4-Difluorophenyl)Propane-1,3-Diyl]Bis[4,1-Phenylene(Difluoromethylene)]}Bis(Phosphonic Acid …
Matched Iupac: … {4-[difluoro(phosphono)methyl]phenyl}-2-(3,4-difluorophenyl)propyl]phenyl}difluoromethyl)phosphonic acid …
Matched Iupac: … {4-[difluoro(phosphono)methyl]phenyl}-2-(3,4-difluorophenyl)propyl]phenyl}difluoromethyl)phosphonic acid …
4-Oxo-2-Phenylmethanesulfonyl-Octahydro-Pyrrolo[1,2-a]Pyrazine-6-Carboxylic Acid [1-(N-Hydroxycarbamimidoyl)-Piperidin-4-Ylmethyl]-Amide
Experimental
Matched Name: … 4-Oxo-2-Phenylmethanesulfonyl-Octahydro-Pyrrolo[1,2-a]Pyrazine-6-Carboxylic Acid [1-(N-Hydroxycarbamimidoyl …
2-[3-({Methyl[1-(2-Naphthoyl)Piperidin-4-Yl]Amino}Carbonyl)-2-Naphthyl]-1-(1-Naphthyl)-2-Oxoethylphosphonic Acid
Experimental
Matched Name: … Methyl[1-(2-Naphthoyl)Piperidin-4-Yl]Amino}Carbonyl)-2-Naphthyl]-1-(1-Naphthyl)-2-Oxoethylphosphonic Acid …
Matched Iupac: … naphthalene-2-carbonyl)piperidin-4-yl]carbamoyl}naphthalen-2-yl)-1-(naphthalen-1-yl)-2-oxoethyl]phosphonic acid …
Matched Iupac: … naphthalene-2-carbonyl)piperidin-4-yl]carbamoyl}naphthalen-2-yl)-1-(naphthalen-1-yl)-2-oxoethyl]phosphonic acid …
2-[2-ETHANESULFONYLAMINO-3-(5-PROPOXY-1H-INDOL-3-YL)-PROPIONYLAMINO]-PENTANEDIOIC ACID 5-AMIDE 1-(4-CARBAMIMIDOYL-BENZYLAMIDE)
Experimental
Matched Name: … 2-[2-ETHANESULFONYLAMINO-3-(5-PROPOXY-1H-INDOL-3-YL)-PROPIONYLAMINO]-PENTANEDIOIC ACID 5-AMIDE 1-(4-CARBAMIMIDOYL-BENZYLAMIDE …
[1-(6-{6-[(1-methylethyl)amino]-1H-indazol-1-yl}pyrazin-2-yl)-1H-pyrrol-3-yl]acetic acid
Experimental
Matched Name: … [1-(6-{6-[(1-methylethyl)amino]-1H-indazol-1-yl}pyrazin-2-yl)-1H-pyrrol-3-yl]acetic acid …
Matched Iupac: … 2-[1-(6-{6-[(propan-2-yl)amino]-1H-indazol-1-yl}pyrazin-2-yl)-1H-pyrrol-3-yl]acetic acid …
Matched Iupac: … 2-[1-(6-{6-[(propan-2-yl)amino]-1H-indazol-1-yl}pyrazin-2-yl)-1H-pyrrol-3-yl]acetic acid …
(1R,4S,7AS)-1-(1-FORMYLPROP-1-EN-1-YL)-4-METHOXY-2,4,5,6,7,7A-HEXAHYDRO-1H-ISOINDOLE-3-CARBOXYLIC ACID
Experimental
Matched Name: … (1R,4S,7AS)-1-(1-FORMYLPROP-1-EN-1-YL)-4-METHOXY-2,4,5,6,7,7A-HEXAHYDRO-1H-ISOINDOLE-3-CARBOXYLIC ACID …
Matched Iupac: … (1R,4S,7aS)-4-methoxy-1-[(2E)-1-oxobut-2-en-2-yl]-2,4,5,6,7,7a-hexahydro-1H-isoindole-3-carboxylic acid …
Matched Iupac: … (1R,4S,7aS)-4-methoxy-1-[(2E)-1-oxobut-2-en-2-yl]-2,4,5,6,7,7a-hexahydro-1H-isoindole-3-carboxylic acid …
1-Beta-Ribofuranosyl-1,3-Diazepinone
Experimental
Matched Name: … 1-Beta-Ribofuranosyl-1,3-Diazepinone …
Methoxy polyethylene glycol-epoetin beta
Methoxy polyethylene glycol-epoetin beta is a chemically synthesised Erythropoiesis Stimulating Agent (ESA) with a longer half-life than erythropoietin. ESA is used to increase synthesis of red blood cells to treat chronic kidney disease associated anemia.
Approved
Matched Name: … Methoxy polyethylene glycol-epoetin beta …
Matched Description: … Methoxy polyethylene glycol-epoetin beta is a chemically synthesised Erythropoiesis Stimulating Agent …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Intercellular Signaling Peptides and Proteins ... methoxy polyethylene glycol-epoetin beta …
Matched Description: … Methoxy polyethylene glycol-epoetin beta is a chemically synthesised Erythropoiesis Stimulating Agent …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Intercellular Signaling Peptides and Proteins ... methoxy polyethylene glycol-epoetin beta …
Bosentan
Bosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals. Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure.
Approved
Investigational
Matched Description: … blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … BOSENTAN BETA 125MG ... BOSENTAN BETA 62.5MG ... TRACLEER ® 62.5 MG TABLETAS RECUBIERTAS DE PELICULA. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … BOSENTAN BETA 125MG ... BOSENTAN BETA 62.5MG ... TRACLEER ® 62.5 MG TABLETAS RECUBIERTAS DE PELICULA. …
5'-Guanylylmethylenebisphosphonate
Experimental
Matched Synonyms: … guanosine 5'-[beta,gamma-methylene]triphosphate …
Matched Iupac: … dihydro-2H-purin-9-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}methyl)phosphonic acid …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … dihydro-2H-purin-9-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}methyl)phosphonic acid …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
D-erythrose 4-phosphate
Experimental
Matched Synonyms: … 4-O-phosphono-D-erythrose …
Matched Name: … D-erythrose 4-phosphate …
Matched Iupac: … [(2R,3R)-2,3-dihydroxy-4-oxobutoxy]phosphonic acid …
Matched Name: … D-erythrose 4-phosphate …
Matched Iupac: … [(2R,3R)-2,3-dihydroxy-4-oxobutoxy]phosphonic acid …
P-113D
P-113D is a novel 12 amino-acid antimicrobial peptide drug derived from histatins, which are compounds found naturally in human saliva. It is being pursued as a potential treatment for cystic fibrosis by Demegen, Inc.
Investigational
Matched Synonyms: … D-PEPTIDE OF THE SEQUENCE AKRHHGYKRKFH - NH2 …
Matched Description: … P-113D is a novel 12 amino-acid antimicrobial peptide drug derived from histatins, which are compounds …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Salivary Proteins and Peptides …
Matched Description: … P-113D is a novel 12 amino-acid antimicrobial peptide drug derived from histatins, which are compounds …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Salivary Proteins and Peptides …
Talditercept alfa
Talditercept alfa is under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and Tolerability of RO7239361 in Ambulatory Boys With Duchenne Muscular Dystrophy).
Investigational
Matched Synonyms: … Immunoglobulin g1 (human fc fragment) fusion protein with peptide (synthetic 17-amino acid linker) fusion …
Matched Description: … under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and …
Matched Description: … under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and …
Lerodalcibep
Lerodalcibep is under investigation in clinical trial NCT05004675 (Trial to Evaluate Efficacy and Safety of LIB003 and Inclisiran in High-risk CVD Patients).
Investigational
Matched Synonyms: … 9 ligand-binding tenth fibronectin type iii domain) fusion protein with peptide (synthetic 6-amino acid …
Matched Description: … Lerodalcibep is under investigation in clinical trial NCT05004675 (Trial to Evaluate Efficacy and Safety ... of LIB003 and Inclisiran in High-risk CVD Patients). …
Matched Description: … Lerodalcibep is under investigation in clinical trial NCT05004675 (Trial to Evaluate Efficacy and Safety ... of LIB003 and Inclisiran in High-risk CVD Patients). …
2'-Deoxy-thymidine-beta-L-rhamnose
Experimental
Matched Name: … 2'-Deoxy-thymidine-beta-L-rhamnose …
Matched Iupac: … 5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy})phosphinic acid …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … 5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy})phosphinic acid …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate
Experimental
Matched Name: … Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate …
Matched Iupac: … -yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}methyl)phosphonic acid …
Matched Iupac: … -yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}methyl)phosphonic acid …
Dapiprazole
Dapiprazole (U.S. trade name Rev-Eyes) is an alpha blocker. It is found in ophthalmic solutions used to reverse mydriasis after an eye examination.
Approved
Matched Synonyms: … 5,6,7,8-Tetrahydro-3-(2-(4-(o-tolyl)-1-piperazinyl)ethyl)-s-triazolo(4,3-a)pyridine …
Matched Description: … Dapiprazole (U.S. trade name Rev-Eyes) is an alpha blocker. …
Matched Salts name: … Dapiprazole hydrochloride …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …
Matched Description: … Dapiprazole (U.S. trade name Rev-Eyes) is an alpha blocker. …
Matched Salts name: … Dapiprazole hydrochloride …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …
JQ1
First-in-class potent and selective inhibitor of the BRD4 signaling pathway.
Investigational
Matched Synonyms: … 6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine-6-acetic acid, 4-(4-chlorophenyl)-2,3,9-trimethyl …
Matched Description: … First-in-class potent and selective inhibitor of the BRD4 signaling pathway.[A252967] …
Matched Description: … First-in-class potent and selective inhibitor of the BRD4 signaling pathway.[A252967] …
Betula pendula pollen
Betula pendula pollen allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Betula pendula pollen ... Betula alba var. pendula pollen ... Betula pendula pollen extract …
Matched Name: … Betula pendula pollen …
Matched Description: … Betula pendula pollen allergenic extract is used in allergenic testing. …
Matched Products: … ITULAZAX 12 SQ-Bet Lyophilisat zur sublingualen Anwendung …
Matched Name: … Betula pendula pollen …
Matched Description: … Betula pendula pollen allergenic extract is used in allergenic testing. …
Matched Products: … ITULAZAX 12 SQ-Bet Lyophilisat zur sublingualen Anwendung …
ASTX-029
ASTX-029 is under investigation in clinical trial NCT03520075 (Study of ASTX029 in Subjects With Advanced Solid Tumors).
Investigational
Matched Synonyms: … -METHYL-1-OXO-, (.ALPHA.R)- ... 2H-PYRAN-4-YL)AMINO)-4-PYRIMIDINYL)-N-((1S)-1-(3-FLUORO-5-METHOXYPHENYL)-2-HYDROXYETHYL)-1,3-DIHYDRO-.ALPHA …
PLX-4720
Experimental
Matched Synonyms: … N-[3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl]propane-1-sulfonamide …
Matched Iupac: … N-(3-{5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide …
Matched Iupac: … N-(3-{5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide …
Displaying drugs 3301 - 3325 of 3973 in total