Displaying drugs 3401 - 3425 of 10056 in total
AGN-201904
Agn 201904 has been used in trials studying the prevention of Peptic Ulcer.
Investigational
Matched Iupac: … 2-[4-({5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methanesulfinyl]-1H-1,3-benzodiazol-1-yl}sulfonyl …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... 2-Pyridinylmethylsulfinylbenzimidazoles …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... 2-Pyridinylmethylsulfinylbenzimidazoles …
RP-L201
Investigational
Matched Synonyms: … Hematopoietic stem cells modified with a lentiviral vector containing the CD18 (integrin beta 2) gene …
Sinefungin
Sinefungin is a solid. This compound belongs to the purine nucleosides and analogues. These are compounds comprising a purine base attached to a sugar. The proteins that adenosyl-ornithine target include RdmB, modification methylase TaqI, rRNA (adenine-N6-)-methyltransferase, and modification methylase RsrI.
Experimental
Matched Synonyms: … (2S,5S)-2,5-diamino-6-[(2R,3S,R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]hexanoic ... 6,9-Diamino-1-(6-amino-9H-purin-9-yl)-1,5,6,7,8,9-hexadeoxydecofuranuronic acid ... 6,9-Diamino-1-(6-amino-9H-purin-9-yl)-1,5,6,7,8,9-hexadeoxy-beta-D-ribo-decofuranuronic acid …
Matched Iupac: … (2S,5S)-2,5-diamino-6-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]hexanoic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … (2S,5S)-2,5-diamino-6-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]hexanoic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Osugacestat
Osugacestat (BMS-906024) has been used in trials studying the treatment of Cancer, Lymphoblastic Leukemia, Acute T-cell, and Precursor T-Cell Lymphoblastic Lymphoma.
Investigational
Matched Synonyms: … Butanediamide, N1-((3S)-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)-2,3-bis(3,3,3- ... (2R,3S)-N1-((S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-2,3-bis(3,3,3-trifluoropropyl …
Matched Iupac: … (2R,3S)-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-2,3-bis(3,3,3-trifluoropropyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … (2R,3S)-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-2,3-bis(3,3,3-trifluoropropyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
TAK-418 free base
Investigational
Matched Synonyms: … 5-((1R,2R)-2-((Cyclopropylmethyl)amino)cyclopropyl)-N-(tetrahydro-2H-pyran-4-yl)thiophene-3-carboxamide …
Matched Iupac: … 5-[(1R,2R)-2-[(cyclopropylmethyl)amino]cyclopropyl]-N-(oxan-4-yl)thiophene-3-carboxamide …
Matched Salts cas: … 1818252-53-7 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 5-[(1R,2R)-2-[(cyclopropylmethyl)amino]cyclopropyl]-N-(oxan-4-yl)thiophene-3-carboxamide …
Matched Salts cas: … 1818252-53-7 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Taxifolin
Experimental
Matched Iupac: … (2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-1-benzopyran-4-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Non COX-2 selective NSAIDS ... Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Non COX-2 selective NSAIDS ... Heterocyclic Compounds, 2-Ring …
LY-2090314
Ly2090314 has been used in trials studying the treatment of Leukemia, Advanced Cancer, and Pancreatic Cancer.
Investigational
Matched Iupac: … 3-[6-fluoro-10-(piperidine-1-carbonyl)-1,10-diazatricyclo[6.4.1.0^{4,13}]trideca-2,4,6,8(13)-tetraen- ... 3-yl]-4-{imidazo[1,2-a]pyridin-3-yl}-2,5-dihydro-1H-pyrrole-2,5-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Glycogen Synthase Kinase 3, antagonists & inhibitors …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Glycogen Synthase Kinase 3, antagonists & inhibitors …
BAL200
Investigational
OAV201
OAV201 is a non-replicating, recombinant adeno-associated virus serotype 9 (AAV9) containing the human Methyl CpG Binding Protein 2B (MECP2B) cDNA under the control of a segment of the murine MECP2 promoter. It was first developed by Novartis and investigated for the treatment of Rett syndrome, but further investigation in clinical...
Investigational
ECT204
ECT204 is an autologous T-cell therapy whereby T cells are genetically modified to target tumor-specific antigens.
Investigational
Doranidazole
Investigational
Matched Synonyms: … (2rs,3sr)-3-((2-nitroimidazol-1-yl)methoxy)butane-1,2,4-triol ... 1,2,4-butanetriol, 3-((2-nitro-1h-imidazol-1-yl)methoxy)-, (2r,3s)-rel- …
Matched Iupac: … (2R,3S)-3-[(2-nitro-1H-imidazol-1-yl)methoxy]butane-1,2,4-triol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … (2R,3S)-3-[(2-nitro-1H-imidazol-1-yl)methoxy]butane-1,2,4-triol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
WU-CART-007
WU-CART-007 consists of allogeneic, fratricide-resistant genetically modified T cells transduced with a 2nd generation 4-1BB-CD3z chimeric antigen receptor targeting human CD7.
Investigational
BQ-788
Investigational
Matched Synonyms: … d-tryptophyl-, sodium salt (1:1) ... D-norleucine, n-(((2r,6s)-2,6-dimethyl-1-piperidinyl)carbonyl)-4-methyl-l-leucyl-1-(methoxycarbonyl)- …
Matched Iupac: … ]-3-[1-(methoxycarbonyl)-1H-indol-3-yl]propanamido]hexanoate ... sodium (2R)-2-[(2R)-2-[(2S)-2-{[(2R,6S)-2,6-dimethylpiperidine-1-carbonyl]amino}-4,4-dimethylpentanamido …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … ]-3-[1-(methoxycarbonyl)-1H-indol-3-yl]propanamido]hexanoate ... sodium (2R)-2-[(2R)-2-[(2S)-2-{[(2R,6S)-2,6-dimethylpiperidine-1-carbonyl]amino}-4,4-dimethylpentanamido …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
ICG-001
Investigational
Matched Synonyms: … (6S,9aS)-N-benzyl-6-(4-hydroxybenzyl)-4,7-dioxo-2-((3-(pyridin-2-yl)isoxazol-5-yl)methyl)-8-(quinolin ... -5-ylmethyl)hexahydro-2H-pyrazino[2,1-c][1,2,4]triazine-1(6H)-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
(3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE
Experimental
Matched Name: … (3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE …
Matched Iupac: … (3Z)-N,N-dimethyl-2-oxo-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylidene]-2,3-dihydro-1H-indole-5-sulfonamide …
Matched Iupac: … (3Z)-N,N-dimethyl-2-oxo-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylidene]-2,3-dihydro-1H-indole-5-sulfonamide …
6-BROMO-13-THIA-2,4,8,12,19-PENTAAZATRICYCLO[12.3.1.1~3,7~]NONADECA-1(18),3(19),4,6,14,16-HEXAENE 13,13-DIOXIDE
Experimental
Matched Name: … 6-BROMO-13-THIA-2,4,8,12,19-PENTAAZATRICYCLO[12.3.1.1~3,7~]NONADECA-1(18),3(19),4,6,14,16-HEXAENE 13,13 …
Matched Iupac: … 6-bromo-13lambda6-thia-2,4,8,12,19-pentaazatricyclo[12.3.1.1^{3,7}]nonadeca-1(18),3(19),4,6,14,16-hexaene …
Matched Iupac: … 6-bromo-13lambda6-thia-2,4,8,12,19-pentaazatricyclo[12.3.1.1^{3,7}]nonadeca-1(18),3(19),4,6,14,16-hexaene …
SB-218078
SB-218078 is a specific inhibitor of CHK1.
Investigational
Matched Synonyms: … 9,10,11,12-tetrahydro-9,12-epoxy-1h-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocine-1,3 ... 9,12-epoxy-1h-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocine-1,3(2h)-dione, 9,10,11,12 …
Matched Iupac: … 26),2(6),7(27),8(13),9,11,20(25),21,23-nonaene-3,5-dione ... oxa-4,14,19-triazaoctacyclo[12.11.2.1^{15,18}.0^{2,6}.0^{7,27}.0^{8,13}.0^{19,26}.0^{20,25}]octacosa-1( …
Matched Iupac: … 26),2(6),7(27),8(13),9,11,20(25),21,23-nonaene-3,5-dione ... oxa-4,14,19-triazaoctacyclo[12.11.2.1^{15,18}.0^{2,6}.0^{7,27}.0^{8,13}.0^{19,26}.0^{20,25}]octacosa-1( …
NP-51
Investigational
Matched Synonyms: … 3-pyridinecarboximidamide, n-(2-hydroxy-3-(1-piperidinyl)propoxy)- ... (+/-)-o-(3-piperidino-2-hydroxy-1-propyl)nicotinic acid amidoxime …
Matched Iupac: … N-[2-hydroxy-3-(piperidin-1-yl)propoxy]pyridine-3-carboximidamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … N-[2-hydroxy-3-(piperidin-1-yl)propoxy]pyridine-3-carboximidamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
(S)-TETRAHYDROFURAN-3-YL (2S,3S)-4-((S)-4-((1R,3R)-3-(2-AMINO-2-OXOETHYL)-2,3-DIHYDRO-1H-INDEN-1-YL)-2-BENZYL-3-OXO-2,3-DIHYDRO-1H-PYRROL-2-YL)-3-HYDROXY-1-PHENYLBUTAN-2-YLCARBAMATE
Experimental
Matched Name: … 2-BENZYL-3-OXO-2,3-DIHYDRO-1H-PYRROL-2-YL)-3-HYDROXY-1-PHENYLBUTAN-2-YLCARBAMATE ... (S)-TETRAHYDROFURAN-3-YL (2S,3S)-4-((S)-4-((1R,3R)-3-(2-AMINO-2-OXOETHYL)-2,3-DIHYDRO-1H-INDEN-1-YL)- …
Matched Iupac: … ]-3-oxo-2,3-dihydro-1H-pyrrol-2-yl]-3-hydroxy-1-phenylbutan-2-yl]carbamate ... (3S)-oxolan-3-yl N-[(2S,3S)-4-[(2S)-2-benzyl-4-[(1R,3R)-3-(carbamoylmethyl)-2,3-dihydro-1H-inden-1-yl …
Matched Iupac: … ]-3-oxo-2,3-dihydro-1H-pyrrol-2-yl]-3-hydroxy-1-phenylbutan-2-yl]carbamate ... (3S)-oxolan-3-yl N-[(2S,3S)-4-[(2S)-2-benzyl-4-[(1R,3R)-3-(carbamoylmethyl)-2,3-dihydro-1H-inden-1-yl …
Crenolanib
Crenolanib is under investigation for the treatment of Diffuse Intrinsic Pontine Glioma and Progressive or Refractory High-Grade Glioma.
Investigational
Matched Iupac: … 1-(2-{5-[(3-methyloxetan-3-yl)methoxy]-1H-1,3-benzodiazol-1-yl}quinolin-8-yl)piperidin-4-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
AX200
AX200, which has been developed for the treatment of stroke, is the most advanced drug candidate and is halfway through the process of gaining clinical approval. The expression of the endogenous AX200 protein in the brain is increased after brain damage. Thus, if this drug administered in the acute phase...
Investigational
6-bromoindirubin-3'-oxime
Experimental
Matched Synonyms: … (2Z,3E)-6'-bromo-2,3'-biindole-2',3(1H,1'H)-dione 3-oxime ... (2Z,3E)-6-Bromoindirubin-3'-oxime …
Matched Name: … 6-bromoindirubin-3'-oxime …
Matched Iupac: … (Z,3E)-6'-bromo-3-(hydroxyimino)-1',2'-dihydro-1H,3H-[2,3'-biindolyliden]-2'-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Glycogen Synthase Kinase 3, antagonists & inhibitors …
Matched Name: … 6-bromoindirubin-3'-oxime …
Matched Iupac: … (Z,3E)-6'-bromo-3-(hydroxyimino)-1',2'-dihydro-1H,3H-[2,3'-biindolyliden]-2'-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Glycogen Synthase Kinase 3, antagonists & inhibitors …
INS018_055
Investigational
Matched Synonyms: … 5’-(4-fluorophenyl)-3’-isopropyl-N-(4-(4-methylpiperazin-1-yl)phenyl)-1H,3’H-[2,4’-biimidazole]-4-carboxamide …
Matched Iupac: … 5'-(4-fluorophenyl)-N-[4-(4-methylpiperazin-1-yl)phenyl]-3'-(propan-2-yl)-3H,3'H-[2,4'-biimidazole]-4 …
Matched Iupac: … 5'-(4-fluorophenyl)-N-[4-(4-methylpiperazin-1-yl)phenyl]-3'-(propan-2-yl)-3H,3'H-[2,4'-biimidazole]-4 …
Promegestone
Experimental
Prexasertib
Prexasertib has been used in trials studying the treatment and basic science of mCRPC, Leukemia, Neoplasm, breast cancer, and Ovarian Cancer, among others.
Investigational
Matched Iupac: … 5-({5-[2-(3-aminopropoxy)-6-methoxyphenyl]-1H-pyrazol-3-yl}amino)pyrazine-2-carbonitrile …
Matched Salts cas: … 1234015-54-3 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Salts cas: … 1234015-54-3 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 3401 - 3425 of 10056 in total