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Fenofibric acid

Fenofibric acid is a lipid-lowering agent that is used in severe hypertriglyceridemia, primary hyperlipidemia, and mixed dyslipidemia. It works to decrease elevated low-density lipoprotein cholesterol, total cholesterol, triglycerides, apolipoprotein B, while increasing high-density lipoprotein cholesterol.[A32038,L12855] Due to its high hydrophilicity and poor absorption profile, prodrug ,fenofibrate, and other conjugated compounds...
Approved
Matched Name: … Fenofibric acid …
Matched Iupac: … 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoic acid …
Matched Description: … ], and other conjugated compounds of fenofibric acid, such as choline fenofibrate, have been developed ... [A32038,L12855] Due to its high hydrophilicity and poor absorption profile,[A32038] prodrug ,[fenofibrate ... Fenofibric acid is a lipid-lowering agent that is used in severe hypertriglyceridemia, primary hyperlipidemia …
Matched Categories: … Peroxisome Proliferator Receptor alpha Agonist ... Acids, Acyclic ... Fibric Acids ... Carboxylic Acids …
Matched Products: … Fenofibric Acid ... Fenofibric acid ... Fenofibric Acid Delayed-Release …

Tefidsogene civaparvovec

Tefidsogene civaparvovec, formerly known as SB-913, is an investigational therapy for genome editing. It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system that inserts a correct copy of the Iduronate 2-Sulfatase (IDS) gene into the albumin locus in hepatocytes. Developed by Sangamo...
Experimental
Matched Synonyms: … IDURONATE 2-SULFATASE (HIDS) TRANSGENE CASSETTE, ENCODING PARTS OF EXON 1 PLUS EXONS 2-9 FROM HIDS AND …
Matched Description: … It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system …

Valproic acid

Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in 1881 by Beverly S. Burton. It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century. In 1963, a serendipitous discovery was made by George Carraz during his investigations into...
Approved
Investigational
Matched Synonyms: … di-n-propylacetic acid ... DPA ... n-DPA …
Matched Name: … Valproic acid …
Matched Iupac: … 2-propylpentanoic acid …
Matched Description: … Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in ... [A178051] It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for ... It is currently a compound of interest in the field of oncology for its anti-proliferative effects and …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Fatty Acids ... valproic acid ... Pentanoic Acids …
Matched Products: … Dom-valproic Acid ... Dom-valproic Acid E.C. ... VALPRO BETA 150 …

Mozafancogene autotemcel

RP-L102 is a lentiviral vector carrying the Fanconi Anemia-A (FANCA) gene currently being developed by Rocket Pharmaceuticals for the treatment of Fanconi anemia type A
Investigational
Matched Synonyms: … Autologous CD34+-enriched Hematopoietic Stem and Progenitor Cells Transduced with Lentiviral Vector Carrying …

CP-12

Investigational
Matched Synonyms: … CYCLIZED P12 (PEPTIDE BOND BETWEEN THE CARBOXY AND AMINO-TERMINAL ENDS OF THE LINEAR PEPTIDE PSHISKYILRWRPK …

Mometasone furoate

Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions[FDA Label][F4292,F4295]. It has a glucocorticoid receptor binding affinity 22 times stronger than dexamethasone and higher than many other corticosteroids as well . Mometasone furoate is formulated as a dry powder...
Approved
Investigational
Vet approved
Matched Description: … Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different ... Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and ... It has a glucocorticoid receptor binding affinity 22 times stronger than [dexamethasone] and higher than …
Matched Mixtures name: … Hyaluronic Acid Sodium Salt 2% / Mometasone Furoate 0.1% / Niacinamide 4% ... HEXALER DUO ... MORFEX 5/100 MCG INHALASYON IÇIN ÖLÇÜLÜ DOZLU AEROSOL ,120 DOZ …
Matched Categories: … formoterol and mometasone …
Matched Products: … Up and Up Allergy ... Nasonex Allergy and Congestion ... Nasal Allergy and Congestion Relief …

Betamethasone

Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmune disorders. Betamethasone has potent glucocorticoid activity and negligible mineralocorticoid activity.
Approved
Vet approved
Matched Synonyms: … beta-Methasone alcohol …
Matched Description: … Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. ... [A192444] It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally ... [A192444] Betamethasone has potent glucocorticoid activity and negligible mineralocorticoid activity. …
Matched Mixtures name: … BACTAFUZ-B Fusidic Acid and Betamethasone Valerate Cream ... AXCEL FUSIDIC ACID-B CREAM ... Betamethasone Sodium Phosphate and Betamethasone Acetate …
Matched Salts name: … Betamethasone acetate …
Matched Categories: … Alimentary Tract and Metabolism ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Sex Hormones and Insulins ... betamethasone and mydriatics ... betamethasone and antiseptics …
Matched Products: … Dr. Throwers Beta ... Betnesol Eye and Ear Drops ... Betnesol Eye and Ear Drops 0.1% …

Ibandronate

Ibandronate, or BM 21.0955, is a third generation, nitrogen containing bisphosphonate similar to zoledronic acid, minodronic acid, and risedronic acid.[A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis.[L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss in dogs. Ibandronate was granted FDA...
Approved
Investigational
Matched Synonyms: … Ibandronic acid …
Matched Iupac: … {1-hydroxy-3-[methyl(pentyl)amino]-1-phosphonopropyl}phosphonic acid …
Matched Description: … ], [minodronic acid], and [risedronic acid]. ... [A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis. ... Ibandronate, or BM 21.0955, is a third generation, nitrogen containing bisphosphonate similar to [zoledronic acid …
Matched Mixtures name: … IBONE D® ... IBONE D 30000 ... IBONE D 30000 …
Matched Categories: … ibandronic acid and colecalciferol ... Drugs Affecting Bone Structure and Mineralization ... ibandronic acid …
Matched Products: … IBANDRONSAEURE BETA 3MG ... ACIDO IBANDRONICO DOC GENERICI ... ASCENDRA 3MG DUO D3 1 + 90 …

Factor IX Complex (Human)

Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting factors found in functioning human plasma. Also known as prothrombin complex concentrate, products containing this complex often include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and low levels of...
Approved
Investigational
Matched Synonyms: … Coagulation factor IX, II, VII and X in combination …
Matched Description: … Coagulation factors are purified from pooled human plasma and subsequently sterilized and treated. ... include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and ... For example, Kcentra (FDA) also contains the antithrombotic proteins C and S, while Bebulin VH (FDA) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …

Ibuprofen

Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. Ibuprofen was finally patented in 1961 and...
Approved
Matched Synonyms: … (±)-p-isobutylhydratropic acid ... 4-isobutylhydratropic acid ... (±)-2-(p-isobutylphenyl)propionic acid …
Matched Iupac: … 2-[4-(2-methylpropyl)phenyl]propanoic acid …
Matched Description: … Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered ... [A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development ... in the UK in 1969 and USA in 1974. …
Matched Mixtures name: … Cimetidine 5% / Ibuprofen 2% / Salicylic Acid 17% ... Oxycodone Hydrochloride and Ibuprofen ... Oxycodone Hydrochloride and Ibuprofen …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Arylpropionic acid NSAIDS ... Antiinflammatory and Antirheumatic Products ... Ibuprofen and isomer …
Matched Products: … Up and Up Dye Free Infants Concentrated Ibuprofen ... Berkley and Jensen ibuprofen childrens dye free ... Betr Pain Relief …

Pantothenic acid

Pantothenic acid, also called pantothenate or vitamin B5 (a B vitamin), is a water-soluble vitamin discovered by Roger J. Williams in 1919. For many animals, pantothenic acid is an essential nutrient as it is required to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats....
Approved
Nutraceutical
Vet approved
Matched Synonyms: … D-pantothenic acid ... (+)-Pantothenic acid …
Matched Name: … Pantothenic acid …
Matched Iupac: … 3-[(2R)-2,4-dihydroxy-3,3-dimethylbutanamido]propanoic acid …
Matched Description: … Pantothenic acid is the amide between pantoic acid and β-alanine and commonly found as its alcohol analog ... Pantothenic acid is an ingredient in some hair and skin care products. ... Only the dextrorotatory (D) isomer of pantothenic acid possesses biological activity. while the levorotatory …
Matched Mixtures name: … Folivane-Plus with Ascorbic Acid Precursors ... PNV Ferrous Fumarate Docusate Folic Acid ... B-complex With Vitamin C, Biotin, Folic Acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Alimentary Tract and Metabolism ... Preparations for Treatment of Wounds and Ulcers …
Matched Products: … D-pantothenic Acid 250mg ... D-pantothenic Acid 250mg Cap ... D Pantothenic Acid Tab 100mg …

Tilmicosin

Tilmicosin is a macrolide antibiotic. It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with Mannheimia haemolytica.
Investigational
Vet approved
Matched Description: … It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory …
Matched Products: … Tilmovet® 200 g/kg Premix for Medicated Feeding Stuff for Pigs and Rabbits …

Tocopherol

Tocopherol exists in four different forms designated as α, β, δ, and γ. They present strong antioxidant activities, and it is determined as the major form of vitamin E. Tocopherol, as a group, is composed of soluble phenolic compounds that consist of a chromanol ring and a 16-carbon phytyl chain....
Approved
Investigational
Matched Synonyms: … tocoferol ... tocophérol ... Tocopherols …
Matched Name: … Tocopherol …
Matched Description: … Tocopherol exists in four different forms designated as α, β, δ, and γ. ... Tocopherol, as a group, is composed of soluble phenolic compounds that consist of a chromanol ring and ... The classification of the tocopherol molecules is designated depending on the number and position of …
Matched Mixtures name: … MultiVitamin Drops with Fluoride and Iron ... Hyaluronic Acid Watery Sun ... Ultra-Potent 2% Kojic Acid Glowing …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition ... tocopherol (vit E) …

Mucor circinelloides f. circinelloides

Mucor circinelloides f. circinelloides allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, mucor circinelloides f. circinelloides …

Carglumic acid

Carglumic acid is a drug used for the treatment of hyperammonemia in patients with a deficiency in N-acetyl glutamate synthase. This rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the blood–brain barrier and cause neurologic problems, cerebral edema, coma, and death. Carglumic acid was...
Approved
Matched Synonyms: … Acide carglumique ... Carglumic acid ... Acidum carglumicum …
Matched Name: … Carglumic acid …
Matched Iupac: … (2S)-2-(carbamoylamino)pentanedioic acid …
Matched Description: … Carglumic acid was approved by the U.S. Food and Drug Administration (FDA) on 18 March 2010. ... cause neurologic problems, cerebral edema, coma, and death. ... disorder results in elevated blood levels of ammonia, which can eventually cross the blood–brain barrier and …
Matched Categories: … Amino Acids and Derivatives ... Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Amino Acids, Acidic ... Amino Acids …
Matched Products: … Carglumic Acid ... Carglumic acid ... ACIDO CARGLUMICO WAYMADE …

Aluminum zirconium tetrachlorohydrex gly

Aluminum zirconium tetrachlorohydrex gly is a common active ingredient in personal care products as an antiperspirant agent. Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing sweat from leaving the body.
Approved
Matched Description: … Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing …
Matched Products: … Axe Dry Gel Anti-perspirant and Deodorant ... Ap 22% (regular,sport,musk and Unscented) ... Mitchum Clear Gel A.P. and Deod.supersport …

Thiamine

Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays...
Approved
Investigational
Nutraceutical
Vet approved
Matched Synonyms: … Thiamin ... Thiamine ... Thiaminum …
Matched Name: … Thiamine …
Matched Description: … Thiamine plays a key role in intracellular glucose metabolism and it is thought that thiamine inhibits ... It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. ... Thiamine plays an important role in helping the body convert carbohydrates and fat into energy. …
Matched Mixtures name: … Iron Polysaccharides Folic Acid DHA ... Folivane-Plus with Ascorbic Acid Precursors ... Vita-vim With Beta-carotene - Tab …
Matched Salts name: … Thiamine mononitrate ... Thiamine hydrochloride ... Thiamine chloride …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition ... thiamine (vit B1) …
Matched Products: … Thiamine Hydrochloride ... Thiamine Hydrochloride Inj 100mg/ml ... Thiamine Hydrochloride Inj 100mg/ml USP …

Beta carotene

Beta-carotene, with the molecular formula C40H56, belongs to the group of carotenoids consisting of isoprene units. The presence of long chains of conjugated double bonds donates beta-carotene with specific colors. It is the most abundant form of carotenoid and it is a precursor of the vitamin A. Beta-carotene is composed...
Approved
Nutraceutical
Matched Synonyms: … Beta carotene ... beta-carotene ... all-trans-β-carotene …
Matched Name: … Beta carotene …
Matched Description: … Beta-carotene is composed of two retinyl groups. ... It is an antioxidant that can be found in yellow, orange and green leafy vegetables and fruits. ... [T162] It is the most abundant form of carotenoid and it is a precursor of the vitamin A. …
Matched Mixtures name: … Iron Polysaccharides Folic Acid DHA ... PNV Ferrous Fumarate Docusate Folic Acid ... Beta-carotene,vitamin C,e and Selenium Combo …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition ... Emollients and Protectives …
Matched Products: … Beta Carotene ... Beta Carotene 25000 U.I. ... Beta-carotene Capsules …

Ivermectin

Ivermectin is a semi-synthetic antiparasitic medication derived from avermectins, a class of highly-active broad-spectrum antiparasitic agents isolated from the fermentation products of Streptomyces avermitilis. Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl-22,23-dihydroavermectin A1a (22,23-dihydroavermectin B1a) and 10% 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro­-25-(1-methylethyl)avermectin A1a (22,23-dihydroavermectin B1b). Ivermectin is mainly used in...
Approved
Investigational
Vet approved
Matched Description: … Due to a number of factors - for example, the relatively low number of patients per trial and the speed ... With the advent of 2020 and the COVID-19 pandemic, ivermectin began garnering notoriety due to its off-label ... use for the prophylaxis and treatment of COVID-19. …
Matched Mixtures name: … Eqvalan Duo Oral Paste for Horse ... Ivermectin 1% / Metronidazole 1% / Niacinamide 4% ... 171083 Ivermectin 1% / Metronidazole 1% / Niacinamide 4% …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Scabicides and Pediculicides …
Matched Products: … IVOMEC Injection 1% w/v for Cattle and Sheep …

Tretinoin

Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). It is an oxidation product in the physiological pathway of vitamin A metabolism. In human circulation, tretinoin is normally found at very low concentrations, approximately 4 to 14 nmol/L. Tretinoin exhibits anti-inflammatory, antineoplastic, antioxidant,...
Approved
Investigational
Nutraceutical
Matched Synonyms: … beta-Retinoic acid ... all-trans-beta-Retinoic acid ... Acide retinoique …
Matched Iupac: … (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid …
Matched Description: … Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of [vitamin ... activates nuclear receptors to regulate epithelial cell growth and differentiation. ... [A257689] Tretinoin exhibits anti-inflammatory, antineoplastic, antioxidant, and free radical-scavenging …
Matched Mixtures name: … Ascorbyl Palmitate 2% / Hyaluronic Acid Sodium Salt 0.2% / Niacinamide 5% / Tretinoin 0.025% ... Clindamycin Phosphate and Tretinion ... Hyaluronic Acid Sodium Salt 0.5% / Niacinamide 4% / Tretinoin 0.1% …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Cell Stimulants and Proliferants …
Matched Products: … RETIN A CREMA DE 0.050% ... RETIN A CREMA DE 0.025% ... Vitamin A Acid …

Glycolic acid

Approved
Investigational
Matched Synonyms: … alpha-Hydroxyacetic acid ... Glycollic acid ... 2-Hydroxyacetic acid …
Matched Name: … Glycolic acid …
Matched Iupac: … 2-hydroxyacetic acid …
Matched Mixtures name: … CREMA CON ACIDO GLICOLICO AL 8% …
Matched Categories: … Acetates ... Acids, Acyclic ... Hydroxy Acids ... Carboxylic Acids …
Matched Products: … Glycolic Acid ... ACIDO GLICOLICO OVOCELL ... Village 11 Factory Relax Day Aha Exfoliating Body …

Chenodeoxycholic acid

Chenodeoxycholic acid (or Chenodiol) is an epimer of ursodeoxycholic acid (DB01586). Chenodeoxycholic acid is a bile acid naturally found in the body. It works by dissolving the cholesterol that makes gallstones and inhibiting production of cholesterol in the liver and absorption in the intestines, which helps to decrease the formation...
Approved
Matched Synonyms: … Chenic acid ... Chenocholic acid ... Acide chenodeoxycholique …
Matched Name: … Chenodeoxycholic acid …
Matched Iupac: … 9aS,9bS,11aR)-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid …
Matched Description: … It works by dissolving the cholesterol that makes gallstones and inhibiting production of cholesterol ... in the liver and absorption in the intestines, which helps to decrease the formation of gallstones. ... Chenodeoxycholic acid is a bile acid naturally found in the body. …
Matched Categories: … Bile Acids and Salts ... Bile acids and derivatives ... Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Cholic Acids …
Matched Products: … ACIDO CHENODESOSSICOLICO LEADIANT ... Chenodeoxycholic Acid Leadiant …

Ceftazidime

Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Matched Description: … a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and ... through inhibition of essential PBPs, result in impaired cell wall homeostasis, loss of cell integrity, and ... [L32935] Ceftazidime was approved by the FDA on July 19, 1985, and is currently available either alone …
Matched Categories: … Thiazines ... beta-Lactams ... beta Lactam Antibiotics …
Matched Products: … Ceftazidime and Dextrose ... CEFTAZIDIME ALVOGEN POWDER FOR SOLUTION FOR INJECTION AND INFUSION 1G/ VIAL ... CEFTAZIDIMA DOC …

Isosorbide mononitrate

Isosorbide mononitrate is an organic nitrate with vasodilating properties. It is an anti-anginal agent that works by relaxing the smooth muscles of both arteries and veins, but but predominantly veins to reduce cardiac preload.[L11698, L11743] Isosorbide mononitrate is an active metabolite of isosorbide dinitrate. Like other organic nitrates, isosorbide mononitrate...
Approved
Matched International brands: … Monotrate …
Matched Synonyms: … Mononitrato de isosorbida ... Iso-5-mononitrate ... Isosorbide mononitrate …
Matched Name: … Isosorbide mononitrate …
Matched Description: … [L11743] Isosorbide mononitrate has a longer duration of action than [nitroglycerin] due to its slow ... onset of absorption and metabolism. ... [L11698] It is available in oral tablets generically and under the brand name ISMO and Monoket. …
Matched Categories: … Nitrates and Nitrites ... isosorbide mononitrate …
Matched Products: … ISOSORBIDE MONONITRATO DOC GENERICI ... Dom-ismn ... Isosorbide Mononitrate …

Ondansetron

A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties. Having been developed in the 1980s by GlaxoSmithKline and approved by the US FDA since January 1991, ondansetron has...
Approved
Withdrawn
Matched Description: … in a single dose, due to a high risk of QT prolongation. ... its approval for the use of all intravenous drug products containing more than 16 mg of ondansetron hydrochloride ... cisplatin, and has reported anxiolytic and neuroleptic properties. …
Matched Salts name: … Ondansetron hydrochloride ... Ondansetron hydrochloride dihydrate …
Matched Categories: … Antiemetics and Antinauseants …
Matched Products: … Ondansetron Hydrochloride and Dextrose ... Ondansetron hydrochloride and dextrose ... Ondansetron and Dextrose …
Displaying drugs 326 - 350 of 3799 in total