Displaying drugs 3476 - 3500 of 3889 in total
Prostaglandin D2
The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages. Among its many biological actions, the most important are its bronchoconstrictor, platelet-activating-factor-inhibitory, and cytotoxic effects.
Investigational
Matched Synonyms: … 11-Dehydroprostaglandin F2-alpha …
Matched Iupac: … (5Z)-7-[(1R,2R,5S)-5-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-3-oxocyclopentyl]hept-5-enoic acid …
Matched Description: … The principal cyclooxygenase metabolite of arachidonic acid. ... It is released upon activation of mast cells and is also synthesized by alveolar macrophages. ... biological actions, the most important are its bronchoconstrictor, platelet-activating-factor-inhibitory, and …
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated …
Matched Iupac: … (5Z)-7-[(1R,2R,5S)-5-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-3-oxocyclopentyl]hept-5-enoic acid …
Matched Description: … The principal cyclooxygenase metabolite of arachidonic acid. ... It is released upon activation of mast cells and is also synthesized by alveolar macrophages. ... biological actions, the most important are its bronchoconstrictor, platelet-activating-factor-inhibitory, and …
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated …
Vocacapsaicin
Investigational
Matched Synonyms: … 1-piperidinecarboxylic acid, 2-((methylamino)methyl)-, 2-methoxy-4-((((6e)-8-methyl-1-oxo-6-nonen-1-yl …
+/-METHYL 4-(AMINOIMINOMETHYL)-BETA-[3- INH (AMINOIMINO)PHENYL]BENZENE PENTANOATE
Experimental
Matched Name: … +/-METHYL 4-(AMINOIMINOMETHYL)-BETA-[3- INH (AMINOIMINO)PHENYL]BENZENE PENTANOATE …
{(2S)-1-[N-(tert-butoxycarbonyl)glycyl]pyrrolidin-2-yl}methyl (3-chlorophenyl)acetate
Experimental
Matched Name: … {(2S)-1-[N-(tert-butoxycarbonyl)glycyl]pyrrolidin-2-yl}methyl (3-chlorophenyl)acetate …
Matched Iupac: … [(2S)-1-(2-{[(tert-butoxy)carbonyl]amino}acetyl)pyrrolidin-2-yl]methyl 2-(3-chlorophenyl)acetate …
Matched Iupac: … [(2S)-1-(2-{[(tert-butoxy)carbonyl]amino}acetyl)pyrrolidin-2-yl]methyl 2-(3-chlorophenyl)acetate …
CAN-106
CAN-106 a novel, long-acting monoclonal antibody directed against human complement C5.
Investigational
Matched Synonyms: … Immunoglobulin G [27-histidine,57-histidine,253-tyrosine,255- threonine,257-glutamic acid], anti-(human …
Ezabenlimab
Investigational
Matched Synonyms: … Immunoglobulin g4 (228-proline), anti-(human programmed cell death protein 1) (human monoclonal bi754091 …
Zimberelimab
Investigational
Matched Synonyms: … Immunoglobulin g4(231-proline), anti-(human programmed cell death protein 1) (human monoclonal ab122 …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
IFx-Hu2.0
IFx-Hu2.0 is an investigational cancer vaccine. It is composed of plasmid DNA encoding the streptococcal membrane protein, Emm55, contained within a cationic polymer.
Investigational
Matched Synonyms: … consisting of pAc/emm55, a plasmid DNA (pDNA), which codes for a modified immunogenic, streptococcal Emm55 protein …
Matched Description: … It is composed of plasmid DNA encoding the streptococcal membrane protein, Emm55, contained within a …
Matched Description: … It is composed of plasmid DNA encoding the streptococcal membrane protein, Emm55, contained within a …
Vixarelimab
Vixarelimab is under investigation in clinical trial NCT03816891 (A Study to Assess the Efficacy, Safety, and Tolerability of KPL-716 in Reducing Pruritus in Prurigo Nodularis).
Investigational
Matched Synonyms: … Immunoglobulin g (234-proline,303-glutamine), anti-(human oncostatin m receptor subunit .beta.) …
Matched Description: … Vixarelimab is under investigation in clinical trial NCT03816891 (A Study to Assess the Efficacy, Safety, and …
Matched Description: … Vixarelimab is under investigation in clinical trial NCT03816891 (A Study to Assess the Efficacy, Safety, and …
Teropavimab
Teropavimab is under investigation in clinical trial NCT05729568 (A Study of GS-5423 and GS-2872 in Combination With Capsid Inhibitor Lenacapavir in Virologically Suppressed Adults With HIV-1 Infection).
Investigational
Matched Synonyms: … Immunoglobulin g1 (434-leucine,440-serine), anti-(human immunodeficiency virus 1 envelope protein gp120env …
Matched Description: … Teropavimab is under investigation in clinical trial NCT05729568 (A Study of GS-5423 and GS-2872 in Combination …
Matched Description: … Teropavimab is under investigation in clinical trial NCT05729568 (A Study of GS-5423 and GS-2872 in Combination …
Nerinetide
Na 1 is under investigation in clinical trial NCT00728182 (Evaluating Neuroprotection in Aneurysm Coiling Therapy).
Investigational
Matched Synonyms: … -GLUTAMYL-L-SERYL-L-.ALPHA.-ASPARTYL- ... -GLUTAMYL-L-SERYL-L-.ALPHA.-ASPARTYL-L-VALINE ... L-TYROSYLGLYCYL-L-ARGINYL-L-LYSYL-L-LYSYL-L-ARGINYL-L-ARGINYL-L-GLUTAMINYL-L-ARGINYL-L-ARGINYL-L-ARGINYL-L-LYSYL-L-LEUCYL-L-SERYL-L-SERYL-L-ISOLEUCYL-L-.ALPHA …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Diclofenamide
A carbonic anhydrase inhibitor that is used in the treatment of glaucoma.
Approved
Investigational
Matched Synonyms: … 4,5-dichloro-benzene-1,3-disulfonic acid diamide …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Cefazolin
A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
Approved
Matched Synonyms: … sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … methyl}-8-oxo-7-[2-(1H-1,2,3,4-tetrazol-1-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … It attains high serum levels and is excreted quickly via the urine. …
Matched Categories: … beta-Lactams ... Thiazines …
Matched Iupac: … methyl}-8-oxo-7-[2-(1H-1,2,3,4-tetrazol-1-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … It attains high serum levels and is excreted quickly via the urine. …
Matched Categories: … beta-Lactams ... Thiazines …
Lirentelimab
Lirentelimab is under investigation in clinical trial NCT04856891 (A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Duodenitis).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS SIALIC ACID-BINDING IG-LIKE LECTIN 8 (SIALOADHESIN FAMILY ... IMMUNOGLOBULIN G1, ANTI-(HUMAN SIALIC ACID-BINDINGE IG-LIKE LECTIN 8) (HUMAN-MUS MUSCULUS MONOCLONAL …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
3-(4-(8-Fluoroquinoline) imidazole(1,2-a)pyridine-7-(1-phenyl-4-(1-(4-methyl piperazine)
Investigational
Matched Synonyms: … 3-(4-(8-fluoroquinoline)imidazole(1,2-a)pyridine-7-(1-phenyl-4-(1-(4-methyl piperazine) …
Matched Name: … 3-(4-(8-Fluoroquinoline) imidazole(1,2-a)pyridine-7-(1-phenyl-4-(1-(4-methyl piperazine) …
Matched Name: … 3-(4-(8-Fluoroquinoline) imidazole(1,2-a)pyridine-7-(1-phenyl-4-(1-(4-methyl piperazine) …
[2,4,6-Triisopropyl-Phenylsulfonyl-L-[3-Amidino-Phenylalanine]]-Piperazine-N'-Beta-Alanine
Experimental
Matched Name: … [2,4,6-Triisopropyl-Phenylsulfonyl-L-[3-Amidino-Phenylalanine]]-Piperazine-N'-Beta-Alanine …
Nebivolol
Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity. Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than atenolol, propranolol, or pindolol. Nebivolol and other beta...
Approved
Investigational
Matched Description: … Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other ... [A182579] Nebivolol and other beta blockers are generally not first line therapies as many patients are ... [A182579] Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure …
Matched Salts name: … Nebivolol hydrochloride …
Matched Categories: … Beta blocking agents and calcium channel blockers ... Beta Blocking Agents and Thiazides ... Beta Blocking Agents, Selective, and Thiazides ... valsartan and nebivolol ... nebivolol and amlodipine …
Matched Products: … NEBIVOLOL HYDROCHLORIDE ... Nebivolol Hydrochloride …
Matched Salts name: … Nebivolol hydrochloride …
Matched Categories: … Beta blocking agents and calcium channel blockers ... Beta Blocking Agents and Thiazides ... Beta Blocking Agents, Selective, and Thiazides ... valsartan and nebivolol ... nebivolol and amlodipine …
Matched Products: … NEBIVOLOL HYDROCHLORIDE ... Nebivolol Hydrochloride …
Methylphenobarbital
A barbiturate that is metabolized to phenobarbital. It has been used for similar purposes, especially in epilepsy, but there is no evidence mephobarbital offers any advantage over phenobarbital.
Approved
Matched Synonyms: … 5-ethyl-1-methyl-5-phenylbarbituric acid …
Matched Categories: … Barbiturates and Derivatives ... Hypnotics and Sedatives ... Phenobarbital and similars …
Matched Categories: … Barbiturates and Derivatives ... Hypnotics and Sedatives ... Phenobarbital and similars …
Felodipine
Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker (CCB)b. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and vasoconstriction. Felodipine is the most potent CCB...
Approved
Investigational
Matched Synonyms: … 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid ethyl methyl ester …
Matched Description: … contraction and vasoconstriction. ... In addition to binding to L-type calcium channels, felodipine binds to a number of calcium-binding proteins ... Felodipine is the most potent CCB in use and is unique in that it exhibits fluorescent activity. …
Matched Categories: … Beta blocking agents and calcium channel blockers ... ACE Inhibitors and Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... ramipril and felodipine ... metoprolol and felodipine …
Matched Description: … contraction and vasoconstriction. ... In addition to binding to L-type calcium channels, felodipine binds to a number of calcium-binding proteins ... Felodipine is the most potent CCB in use and is unique in that it exhibits fluorescent activity. …
Matched Categories: … Beta blocking agents and calcium channel blockers ... ACE Inhibitors and Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... ramipril and felodipine ... metoprolol and felodipine …
Ezetimibe
Ezetimibe is a lipid-lowering compound that inhibits intestinal cholesterol and phytosterol absorption. The discovery and research of this drug began in the early 1990s, after the intravenous administration of radiolabelled ezetimibe in rats revealed that it was being localized within enterocytes of the intestinal villi - this prompted studies investigating...
Approved
Matched Description: … [L11347]
Unlike other classes of cholesterol-reducing compounds including statins and bile acid sequestrants ... affect the absorption of fat-soluble nutrients such as fat-soluble vitamins, triglycerides, or bile acids ... Ezetimibe is a lipid-lowering compound that inhibits intestinal cholesterol and phytosterol absorption …
Matched Mixtures name: … Ezetimibe and Simvastatin ... Ezetimibe and Simvastatin ... Ezetimibe and Simvastatin …
Matched Categories: … bempedoic acid and ezetimibe ... simvastatin and ezetimibe ... pravastatin and ezetimibe ... atorvastatin and ezetimibe ... rosuvastatin and ezetimibe …
Matched Products: … EZETIMIB BETA 10 MG …
Matched Mixtures name: … Ezetimibe and Simvastatin ... Ezetimibe and Simvastatin ... Ezetimibe and Simvastatin …
Matched Categories: … bempedoic acid and ezetimibe ... simvastatin and ezetimibe ... pravastatin and ezetimibe ... atorvastatin and ezetimibe ... rosuvastatin and ezetimibe …
Matched Products: … EZETIMIB BETA 10 MG …
Peginterferon alfa-2a
Peginterferon alfa-2a is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Investigational
Matched Synonyms: … Pegylated interferon alpha-2a …
Matched Description: … development of endocrine and autoimmune disorders, retinopathies, cardiovascular and neuropsychiatric ... categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and ... the janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Interferon alpha ... Antineoplastic and Immunomodulating Agents ... Proteins …
Matched Description: … development of endocrine and autoimmune disorders, retinopathies, cardiovascular and neuropsychiatric ... categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and ... the janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Interferon alpha ... Antineoplastic and Immunomodulating Agents ... Proteins …
Betazole
A histamine H2 agonist used clinically to test gastric secretory function.
Approved
Matched Synonyms: … 3-(beta-aminoethyl)pyrazole …
Matched Salts name: … Betazole hydrochloride …
Matched Salts name: … Betazole hydrochloride …
Telbivudine
Telbivudine is a synthetic thymidine nucleoside analog with specific activity against the hepatitis B virus. Telbivudine is orally administered, with good tolerance, lack of toxicity and no dose-limiting side effects.
Approved
Investigational
Matched Synonyms: … Beta-l-thymidine …
Matched Description: … Telbivudine is orally administered, with good tolerance, lack of toxicity and no dose-limiting side effects …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Nucleosides and Nucleotides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors ... Nucleic Acid Synthesis Inhibitors …
Matched Description: … Telbivudine is orally administered, with good tolerance, lack of toxicity and no dose-limiting side effects …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Nucleosides and Nucleotides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors ... Nucleic Acid Synthesis Inhibitors …
3-(5-amino-7-hydroxy-(1,2,3)triazolo(4,5-d)pyrimidin-2-yl)benzoic acid
Experimental
Matched Name: … 3-(5-amino-7-hydroxy-(1,2,3)triazolo(4,5-d)pyrimidin-2-yl)benzoic acid …
Matched Iupac: … 3-{5-amino-7-hydroxy-2H-[1,2,3]triazolo[4,5-d]pyrimidin-2-yl}benzoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Iupac: … 3-{5-amino-7-hydroxy-2H-[1,2,3]triazolo[4,5-d]pyrimidin-2-yl}benzoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
2-Amino-3-[5-(Amino-Carboxy-Methyl)-2,3-Dihydro-Isoxazol-3-Ylsulfanyl]-Propionic Acid
Experimental
Matched Name: … 2-Amino-3-[5-(Amino-Carboxy-Methyl)-2,3-Dihydro-Isoxazol-3-Ylsulfanyl]-Propionic Acid …
Matched Iupac: … (2R)-2-amino-3-{[(3R)-5-[(S)-amino(carboxy)methyl]-2,3-dihydro-1,2-oxazol-3-yl]sulfanyl}propanoic acid …
Matched Iupac: … (2R)-2-amino-3-{[(3R)-5-[(S)-amino(carboxy)methyl]-2,3-dihydro-1,2-oxazol-3-yl]sulfanyl}propanoic acid …
Displaying drugs 3476 - 3500 of 3889 in total