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Displaying drugs 351 - 375 of 2346 in total

Phenylephrine

Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil, and induce local vasoconstriction. The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s. Phenylephrine was granted FDA approval in 1939.
Approved
Matched Description: … alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil,[L9413] and …
Matched Mixtures name: … Hemorrhoidal Cream with Aloe ... Up and Up Nighttime Flu and Severe Cold and Cough ... Up and Up Flu and Severe Cold and Cough Relief …
Matched Categories: … Mydriatics and Cycloplegics ... phenylephrine and ketorolac ... Adrenergic and Dopaminergic Agents ... Decongestants and Antiallergics ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Up and Up Sinus PE ... CareOne Cold and Sinus ... Uline Sinus and Congestion …

Capsicum oleoresin

Capsicum oleoresin is an oily organic resin derived from the fruit of plants in the Capsicum genus, such as chilli peppers. When the plants are finely ground, capsicum oleoresin is formed after the extraction process of capsaicin using oragnic solvents such as ethanol. It is commonly used as a culinary...
Approved
Matched Description: … pains of muscles and joints as an active ingredient in topical OTC preparations and has been studied ... , nordihydrocapsaicin, homocapsaicin, and homodihydrocapsaicin [A32318]. ... [DB06774] and dihydrocapsaicin are the most pungent capsaicinoid analogues [A32318]. …
Matched Mixtures name: … Half and Half Balm ... Hot Spice and Ice …
Matched Products: … Sheffield Arthritis and Muscle Pain Relief …

Palonosetron

Palonosetron (INN, trade name Aloxi) is an antagonist of 5-HT3 receptors that is indicated for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). It is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that appear more than 24 hours after the first...
Approved
Investigational
Matched Description: … Palonosetron (INN, trade name Aloxi) is an antagonist of 5-HT3 receptors that is indicated for the prevention ... and treatment of chemotherapy-induced nausea and vomiting (CINV). ... Food and Drug Administration. …
Matched Categories: … Alimentary Tract and Metabolism ... Antiemetics and Antinauseants …
Matched Products: … Aloxi ... ALOXI ... ALOXI 500mcg Soft Capsules …

Linvoseltamab

Linvoseltamab is an investigational bispecific antibody. It promotes the interaction of B-cell maturation antigen (BCMA) on multiple myeloma cells with CD3-expressing T cells.
Investigational
Matched Synonyms: … human IgG4-based anti-CD3 x anti-BCMA bispecific monoclonal antibody that binds to CD3 and BCMA …

GTP-506

GTP-506 is a gene therapy formed by two vectors, a nuclease vector targeting gene editing in the well-characterized PCSK9 gene locus and a therapeutic donor vector that inserts the OTC gene to provide the desired genetic correction.
Investigational
Matched Synonyms: … Non-replicating recombinant adeno-associated virus serotype rh79 (AAVrh.79) vectors: AAVrh79.TBG.M2PCSK9.WPRE.bGH and …
Matched Description: … by two vectors, a nuclease vector targeting gene editing in the well-characterized PCSK9 gene locus and …

Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase

Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase is an investigational lentiviral gene therapy. It comprises autologous CD34+ hematopoietic stem and progenitor cells (HSPCs) that had been genetically modified ex vivo with EFS-ADA LV.
Investigational
Matched Name: … Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase …
Matched Description: … Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase is an investigational ... It comprises autologous CD34+ hematopoietic stem and progenitor cells (HSPCs) that had been genetically …

Cinnamic acid

Investigational
Matched Synonyms: … Cinnamic acidum ... E-cinnamic acid ... 3-phenylacrylic acid …
Matched Name: … Cinnamic acid …
Matched Iupac: … (2E)-3-phenylprop-2-enoic acid …
Matched Categories: … Heparin and similars ... Acids, Carbocyclic ... Carboxylic Acids …

Amaranthus retroflexus pollen

Amaranthus retroflexus pollen is the pollen of the Amaranthus retroflexus plant. Amaranthus retroflexus pollen is mainly used in allergenic testing.
Approved
Matched Products: … Pollens - Weeds and Garden Plants, Pigweed, Rough Redroot Amaranthus retroflexus …

CVac

Approved
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with recombinant human fusion protein (MUCIN1 and Glutathione S Transferase …

AMG 424

AMG 424 is a novel, humanized, anti-CD3/CD38 bispecific monoclonal antibody being investigated for multiple myeloma.
Investigational
Matched Synonyms: … Humanized Bi-Specific Xmab(R) T Cell Recruiting Antibody Construct Directed Against Cd3 And Cd38 …

NTLA-2002

NTLA-2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger RNA (mRNA000042) encoding Cas9. It is an investigational therapy designed to knock out the target gene kallikrein B1 (KLKB1) to reduce plasma kallikrein activity, thereby preventing hereditary angioedema attacks.
Investigational
Matched Synonyms: … lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger …
Matched Description: … 2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and …

TPX-4589

TPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload MC-VC-PAB-MMAE.
Investigational
Matched Synonyms: … Antibody drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload …
Matched Description: … TPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and …

Oxothiazolidinecarboxylic acid

Procysteine has been used in trials studying the treatment of HIV Infections.
Investigational
Matched Synonyms: … (-)-2-OXO-4-THIAZOLIDINECARBOXYLIC ACID ... (R)-2-OXOTHIAZOLIDINE-4-CARBOXYLIC ACID ... L-2-OXO-4-THIAZOLIDINECARBOXYLIC ACI …
Matched Name: … Oxothiazolidinecarboxylic acid …
Matched Iupac: … (4R)-2-oxo-1,3-thiazolidine-4-carboxylic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Imino Acids ... Amino Acids, Cyclic …

Anbenitamab

Investigational
Matched Synonyms: … FC-fusion bispecific antibody targeting extracellular domains II and IV of HER 2 and FC-fusion bispecific ... IgG1 antibody inhibiting PD-L1 and CTLA-4 …

Heptanoic acid

Experimental
Investigational
Matched Synonyms: … Enanthic acid ... Heptoic acid ... Heptanoic acid …
Matched Name: … Heptanoic acid …
Matched Iupac: … heptanoic acid …

Nicotine

Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
Approved
Matched Description: … the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and …
Matched Mixtures name: … Nicorette and Aquafresh Fruit Chill and Extreme Clean Whitening …
Matched Products: … Up and Up Nicotine ... Up and Up nicotine ... Up and Up Mini Nicotine …

Ambrosia artemisiifolia pollen

Ambrosia artemisiifolia pollen is the pollen of the Ambrosia artemisiifolia plant. Ambrosia artemisiifolia pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … Short and Giant Ragweed Pollen Mix ... Pollens - Weeds and Garden Plants, Ragweed, Mixed Ambrosia ... Pollens - Weeds and Garden Plants, Ragweed, Mixed Ambrosia …
Matched Products: … Pollens - Weeds and Garden Plants, Short Ragweed, Ambrosia artemisiifolia …

Polyethylene glycol 400

Polyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain various derivatives and have various functions. Because many PEG types are hydrophilic, they are favorably used as enhancers of penetration, and used heavily in topical dermatological preparations. PEGs, along with their many nonionic derivatives, are...
Approved
Matched Description: … PEGs, along with their many nonionic derivatives, are widely utilized in cosmetic products as surfactants ... various derivatives and have various functions. ... , emulsifiers, cleansing agents, humectants, and skin conditioners. …
Matched Mixtures name: … Redness reliever and Lubricant ... Systane Day and Night Value Pack ... Systane Day and Night Value Pack …
Matched Products: … Foster and Thrive Dry Eye Relief …

Phytic acid

Phytic acid is under investigation in clinical trial NCT01000233 (Value of Oral Phytate (InsP6) in the Prevention of Progression of the Cardiovascular Calcifications).
Investigational
Matched Synonyms: … Fytic acid ... Acido fitico ... Acide fytique …
Matched Name: … Phytic acid …
Matched Iupac: … {[(1s,2R,3R,4r,5S,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl]oxy}phosphonic acid …
Matched Description: … Phytic acid is under investigation in clinical trial NCT01000233 (Value of Oral Phytate (InsP6) in the …

Spanlecortemlocel

Investigational
Matched Synonyms: … ALLOGENEIC UMBILICAL CORD BLOOD-DERIVED HEMATOPOIETIC STEM AND PROGENITOR CELLS MGTA-456 ... Allogeneic umbilical cord blood (UCB) cell therapy product consisting of two cell fractions (CD34 enriched and …

Cefoxitin

Cefoxitin is a semi-synthetic, broad-spectrum cepha antibiotic for intravenous administration. It is derived from cephamycin C, which is produced by Streptomyces lactamdurans.
Approved
Matched Synonyms: … methyl]-7-methoxy-8-oxo-7-[(thiophen-2-enyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … methyl]-7-methoxy-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Products: … Cefoxitin and Dextrose …

Viagenpumatucel-L

Viagenpumatucel-L is under investigation in clinical trial NCT02117024 (A Phase 2 Study of Viagenpumatucel-l (HS-110) in Patients With Non-small Cell Lung Cancer).
Investigational
Matched Synonyms: … Gp96-igg1-fc fusion protein and hla-a1 expressing, irradiated ad-100 whole cell vaccine …

TN-201

TN-201 is a gene therapy comprising a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human MYBPC3 gene.
Investigational
Matched Synonyms: … Native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type …
Matched Description: … comprising a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and …

Tricarballylic acid

Experimental
Matched Synonyms: … Carballylic acid ... 3-carboxyglutaric acid ... β-carboxyglutaric acid …
Matched Name: … Tricarballylic acid …
Matched Iupac: … propane-1,2,3-tricarboxylic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …

Atacicept

Atacicept is a recombinant fusion protein combined with the extracellular ligand binding portion of TACI.
Investigational
Matched Synonyms: … Human Transmembrane Activator and CAML Interactor (TACI) Immunoglobulin G1 Fc Domain Fusion Protein ( …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 351 - 375 of 2346 in total