Displaying drugs 376 - 400 of 13476 in total
Acetohexamide
A sulfonylurea hypoglycemic agent that is metabolized in the liver to 1-hydrohexamide. Acetohexamide has been discontinued in the US market.
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-[(4-acetylbenzene)sulfonyl]-3-cyclohexylurea 4-acetyl-N-(cyclohexylcarbamoyl)benzenesulfonamide …
Matched Iupac: … 1-(4-acetylbenzenesulfonyl)-3-cyclohexylurea …
Matched Iupac: … 1-(4-acetylbenzenesulfonyl)-3-cyclohexylurea …
Nedocromil
A pyranoquinolone derivative that inhibits activation of inflammatory cells which are associated with asthma, including eosinophils, neutrophils, macrophages, mast cells, monocytes, and platelets.
Approved
Investigational
Matched Categories: … 4-Quinolones ... Heterocyclic Compounds, 2-Ring …
Sodium citrate
Sodium citrate is the sodium salt of citric acid. It is white, crystalline powder or white, granular crystals, slightly deliquescent in moist air, freely soluble in water,
practically insoluble in alcohol. Like citric acid, it has a sour taste.
From the medical point of view, it is used as alkalinizing...
Approved
Investigational
Matched Iupac: … trisodium 2-hydroxypropane-1,2,3-tricarboxylate …
Matched Mixtures name: … B S S STERILE IRRIGATING SOLUTION ... MINICA S ENEMA ... Cytra-2 …
Matched Products: … Sodium Citrate 4% w/v Anticoagulant ... Anticoagulant Sodium Citrate Sol 4% USP ... Anticoagulant Sodium Citrate 4% W/V Solution, USP …
Matched Mixtures name: … B S S STERILE IRRIGATING SOLUTION ... MINICA S ENEMA ... Cytra-2 …
Matched Products: … Sodium Citrate 4% w/v Anticoagulant ... Anticoagulant Sodium Citrate Sol 4% USP ... Anticoagulant Sodium Citrate 4% W/V Solution, USP …
Pentobarbital
A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA...
Approved
Investigational
Vet approved
Matched Iupac: … 5-ethyl-5-(pentan-2-yl)-1,3-diazinane-2,4,6-trione …
Masoprocol
A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in fats and oils. [PubChem]
Approved
Investigational
Matched Synonyms: … meso-4-[4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol …
Matched Iupac: … 4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol …
Matched Iupac: … 4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol …
Polyethylene glycol
Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage.[A190975,A190978] PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water molecules per one PEG molecule. Molecular weights of PEGs vary...
Approved
Vet approved
Matched Products: … GOLYTELY BAGIRSAK TEMIZLEME TOZU, 4 L ... Forlax 4 g Pulver zur Herstellung einer Lösung zum Einnehmen ... CASENLAX 4 G ORAL ÇÖZELTİ HAZIRLAMAK İÇİN TOZ İÇEREN SAŞE , 20 ADET …
Clobazam
Clobazam belongs to the 1,5-benzodiazepine class of drugs and is marketed under different names, Onfi, Frisium, Urbanyl, and others. . Clobazam was first synthesized in 1966 and first published in 1969, following the incidental synthesis and discovery of the first benzodiazepine chlordiazepoxide in the 1950s. Unlike older 1,4-benzodiazepines, clobazam has...
Approved
Illicit
Matched Description: … [A256963,A256868] This is likely because of clobazam's higher affinity to the α2 subunit of …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Bisphenol A diglycidyl ether
Approved
Experimental
Matched Synonyms: … 2,2-Bis(4-glycidyloxyphenyl)propane ... 2,2-bis(4'-glycidyloxyphenyl)propane …
Matched Iupac: … 2-{[4-(2-{4-[(oxiran-2-yl)methoxy]phenyl}propan-2-yl)phenoxy]methyl}oxirane …
Matched Iupac: … 2-{[4-(2-{4-[(oxiran-2-yl)methoxy]phenyl}propan-2-yl)phenoxy]methyl}oxirane …
Etanercept
Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1.[L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1....
Approved
Investigational
Matched Products: … COZ.ICIN KULLANIMA HAZIR KALEM, 2 ADET ... COZ.ICIN KULLANIMA HAZIR KALEM, 4 ADET ... ENBREL 25MG ENJEKSIYONLUK SOLUSYON ICIN TOZ FLAKON, 4 ADET …
Ergosterol
A steroid of interest both because its biosynthesis in FUNGI is a target of ANTIFUNGAL AGENTS, notably AZOLES, and because when it is present in SKIN of animals, ULTRAVIOLET RAYS break a bond to result in ERGOCALCIFEROL.
Approved
Experimental
Matched Iupac: … (1R,3aR,7S,9aR,9bS,11aR)-1-[(2R,3E,5R)-5,6-dimethylhept-3-en-2-yl]-9a,11a-dimethyl-1H,2H,3H,3aH,6H,7H …
Felodipine
Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker (CCB)b. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and vasoconstriction. Felodipine is the most potent CCB...
Approved
Investigational
Matched Synonyms: … (±)-ethyl methyl 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate ... 3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate ... 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid ethyl methyl ester …
Matched Iupac: … 3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Iupac: … 3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate …
Bictegravir
Bictegravir is a recently approved investigational drug that has been used in trials studying the treatment of HIV-1 and HIV-2 infection. It has been approved for HIV-1 monotherapy combined with 2 other antiretrovirals in a single tablet.
Approved
Investigational
Matched Description: … approved investigational drug that has been used in trials studying the treatment of HIV-1 and HIV-2 ... It has been approved for HIV-1 monotherapy combined with 2 other antiretrovirals in a single tablet. …
Finafloxacin
Finafloxacin is a fluoroquinolone antibiotic indicated in the treatment of acute otitis externa (swimmer's ear) caused by the bacteria Pseudomonas aeruginosa and Staphylococcus aureus. Finafloxacin is marketed by Novartis under the brand Xtoro™, and was approved by the FDA in December 2014.
Approved
Investigational
Matched Synonyms: … 8-Cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b][1,4]oxazin-6(2H)-yl]-4-oxo-1,4-dihydro …
Matched Iupac: … 7-[(4aS,7aS)-octahydropyrrolo[3,4-b]morpholin-6-yl]-8-cyano-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 7-[(4aS,7aS)-octahydropyrrolo[3,4-b]morpholin-6-yl]-8-cyano-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Lucinactant
Lucinactant is a new synthetic peptide-containing surfactant for intratracheal use. It contains sinapultide, a novel, hydrophobic, 21-amino acid peptide (leucine and lysine repeating units, KL4 peptide) designed to mimic human surfactant protein-B (SB-P). More specifically, it mimics the C-terminal amphipathic helical domain of this protein. It also consists of phospholipids...
Approved
Investigational
Rupatadine
Rupatadine is a dual histamine H1 receptor and platelet activating factor receptor antagonist that is used for symptomatic relief in seasonal and perennial rhinitis as well as chronic spontaneous urticaria. It was approved for marketing in Canada under the tradename Rupall and comes in tablet formulation for adult use and...
Approved
Matched Iupac: … 13-chloro-2-{1-[(5-methylpyridin-3-yl)methyl]piperidin-4-ylidene}-4-azatricyclo[9.4.0.0^{3,8}]pentadeca …
Tecovirimat
The World Health Organization declared smallpox, a contagious and sometimes fatal infectious disease, eradicated in 1980. However, there have been longstanding concerns that smallpox may be used as a bioweapon.[A35133,L3614] Tecovirimat is an antiviral drug that was identified via a high-throughput screen in 2002. It is effective against all orthopoxviruses,...
Approved
Investigational
Matched Iupac: … N-[(1R,2R,6S,7S,8S,10R)-3,5-dioxo-4-azatetracyclo[5.3.2.0^{2,6}.0^{8,10}]dodec-11-en-4-yl]-4-(trifluoromethyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Dichlorobenzyl alcohol
Dichlorobenzyl alcohol is a mild antiseptic with a broad spectrum for bacterial and virus associated with mouth and throat infections. Dichlorobenzyl alcohol is considered as an active ingredient found in several marketed OTC products by Health Canada which has categorized this agent as an anatomical therapeutic chemical. On the other...
Approved
Mucor plumbeus
Mucor plumbeus is a fungus which can provoke allergic reactions. Mucor plumbeus extract is used in allergenic testing.
Approved
Matched Mixtures name: … Mold Mix 2 ... Mold Mix 2 ... Mold Mix 2 …
Vitamin A
Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of carotenoids found in plants. It is enriched in...
Approved
Nutraceutical
Vet approved
Matched Salts cas: … 79-81-2 …
Matched Mixtures name: … Mvc 9+4 Inj ... For-2 ... Kordel"s Kid"s Multivitamins Plus Lysine Chewable Tablet …
Matched Products: … VITAMIN A (S/C TABLET ) …
Matched Mixtures name: … Mvc 9+4 Inj ... For-2 ... Kordel"s Kid"s Multivitamins Plus Lysine Chewable Tablet …
Matched Products: … VITAMIN A (S/C TABLET ) …
Sutimlimab
Cold agglutinin disease (CAD) is a type of autoimmune hemolytic anemia (AIHA) in which autoantibodies directed against red blood cell surface antigens cause hemolysis at low (3-4°C) temperatures.[A245154,L40114] This cold subtype accounts for approximately 15-25% of all AIHA and is more common in the elderly.[A245159,L40114] In approximately 90% of cases,...
Approved
Investigational
Matched Synonyms: … Humanized IgG4 monoclonal antibody against total complement component 1, subcomponent s …
Matched Description: … in which autoantibodies directed against red blood cell surface antigens cause hemolysis at low (3-4° ... M (IgM) autoantibodies towards the I antigen on erythrocytes - these antibodies react optimally at 4° …
Matched Description: … in which autoantibodies directed against red blood cell surface antigens cause hemolysis at low (3-4° ... M (IgM) autoantibodies towards the I antigen on erythrocytes - these antibodies react optimally at 4° …
Levonordefrin
Levonordefrin acts as a topical nasal decongestant and vasoconstrictor, most often used in dentistry.
Approved
Matched Iupac: … 4-[(1R,2S)-2-amino-1-hydroxypropyl]benzene-1,2-diol …
Matched Mixtures name: … Scandonest 2% L ... Isocaine HCl Inj 2% ... Carbocaine 2% With Neo-cobefrin …
Matched Mixtures name: … Scandonest 2% L ... Isocaine HCl Inj 2% ... Carbocaine 2% With Neo-cobefrin …
Cochliobolus spicifer
Cochliobolus spicifer is a fungus which can provoke allergic reactions. Cochliobolus spicifer extract is used in allergenic testing.
Approved
Matched Mixtures name: … Mold Mix 2 ... Mold Mix 2 ... Mold Mix 2 …
Crisaborole
Crisaborole is a novel oxaborole approved by FDA on December 14, 2016 as Eucrisa, a topical treatment of for mild to moderate atopic dermatitis.
This non-steroidal agent is efficacious in improving disease severity, reducing the risk of infection and reducing the signs and symptoms in patients 2 years old and...
Approved
Investigational
Matched Iupac: … 4-[(1-hydroxy-1,3-dihydro-2,1-benzoxaborol-5-yl)oxy]benzonitrile …
Matched Description: … atom, which facilitates skin penetration and binding to the bimetal center of the phosphodiesterase 4 ... improving disease severity, reducing the risk of infection and reducing the signs and symptoms in patients 2 …
Matched Categories: … Phosphodiesterase 4 Inhibitors …
Matched Description: … atom, which facilitates skin penetration and binding to the bimetal center of the phosphodiesterase 4 ... improving disease severity, reducing the risk of infection and reducing the signs and symptoms in patients 2 …
Matched Categories: … Phosphodiesterase 4 Inhibitors …
Gibberella fujikuroi
Gibberella fujikuroi allergenic extract is used in allergenic testing.
Approved
Matched Mixtures name: … Mold Mix 2 ... Mold Mix 2 ... Mold Mix 2 …
Alogliptin
Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 (DPP-4). Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conversion in vivo to the (S)-enantiomer. FDA approved January 25, 2013.
Approved
Matched Iupac: … 2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl}methyl)benzonitrile …
Matched Description: … (DPP-4). ... It undergoes little or no chiral conversion in vivo to the (S)-enantiomer. ... Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 …
Matched Description: … (DPP-4). ... It undergoes little or no chiral conversion in vivo to the (S)-enantiomer. ... Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 …
Displaying drugs 376 - 400 of 13476 in total