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Displaying drugs 376 - 400 of 6246 in total
Magnesium carbonate, also known as magnesite, is a common over the counter remedy for heartburn and upset stomach caused by overproduction of acid in the stomach [FDA Label].
Approved
Investigational
Matched Iupac: … magnesium(2+) carbonate …
Matched Description: … Magnesium carbonate, also known as magnesite, is a common over the counter remedy for heartburn and upset …
Matched Mixtures name: … Mag/cal 1:1 Capsules W Vitamin D ... Isotonix Vitamin B-folic Acid-mineral Supple ... Isotonix Advanced B-complex Vitamins With Potassium and Magnesium …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Brivudine is used in the treatment of herpes zoster. Although not approved in the U.S. or Canada, it is approved in several European countries.
Approved
Investigational
Matched Synonyms: … (E)-5-(2-Bromovinyl)-deoxyuridine …
Matched Iupac: … 5-[(1E)-2-bromoethenyl]-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear. As of January 29 2018, CutisPharma's Firvanq is the only FDA approved vancomycin oral liquid treatment option available for the the treatment of...
Approved
Matched Iupac: … -pentaazaoctacyclo[26.14.2.2^{3,6}.2^{14,17}.1^{8,12}.1^{29,33}.0^{10,25}.0^{34,39}]pentaconta-3,5,8,10,12 ... (1S,2R,18R,19R,22S,25R,28R,40S)-48-{[(2S,3R,4S,5S,6R)-3-{[(2S,4S,5S,6S)-4-amino-5-hydroxy-4,6-dimethyloxan ... -2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-22-(carbamoylmethyl)-5,47-dichloro-2,18,32,35,37 ... -pentahydroxy-19-[(2R)-4-methyl-2-(methylamino)pentanamido]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43 …
Matched Description: … It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to ... As of January 29 2018, CutisPharma's Firvanq is the only FDA approved vancomycin oral liquid treatment …
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Matched Products: … INJOVAN®500 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... INJOVAN®1000 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... VANCOSALA 500 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …
Carbamide peroxide, also known as urea-hydrogen peroxide, is a water-soluble, white crystalline solid compound consisting of hydrogen peroxide and urea. As it is a source of hydrogen peroxide, it can be found in disinfecting and dental bleaching products. Some adverse effects of carbamide peroxide as a dental bleaching agent include...
Approved
Matched Description: … /or gingival irritation led by unstable and reactive H+ free radicals and low pH from prolonged use. ... Carbamide peroxide, also known as urea-hydrogen peroxide, is a water-soluble, white crystalline solid ... As it is a source of hydrogen peroxide, it can be found in disinfecting and dental bleaching products …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Wax B Gone Ear Wax Removal Drops …
Aprocitentan is a dual antagonist of endothelin receptors A and B used for treatment-resistant hypertension. It is the active metabolite of macitentan. Approximately 10-15% of patients with hypertension have resistant hypertension, defined as uncontrolled high blood pressure despite the combined use of a renin-angiotensin system blocker, a calcium channel blocker,...
Approved
Investigational
Matched Iupac: … N-[5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl]aminosulfonamide …
Matched Description: … Aprocitentan is a dual antagonist of endothelin receptors A and B used for treatment-resistant hypertension ... renin-angiotensin system blocker, a calcium channel blocker, and a diuretic at maximally tolerated doses ... have resistant hypertension, defined as uncontrolled high blood pressure despite the combined use of a
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Bazedoxifene is a third generation selective estrogen receptor modulator (SERM), developed by Pfizer following the completion of their takeover of Wyeth Pharmaceuticals. In late 2013, Pfizer received approval for bazedoxifene as part of the combination drug DUAVEE in the prevention (not treatment) of postmenopausal osteoporosis. It is approved in the...
Approved
Investigational
Matched Iupac: … 1-({4-[2-(azepan-1-yl)ethoxy]phenyl}methyl)-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol …
Matched Description: … Bazedoxifene is a third generation selective estrogen receptor modulator (SERM), developed by Pfizer …
Matched Salts cas: … 198481-33-3
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Cetirizine, also commonly known as Zyrtec, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and other symptoms , . One of the most common uses for this drug is for a condition called allergic...
Approved
Matched Iupac: … 2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid …
Matched Description: … One of the most common uses for this drug is for a condition called _allergic rhinitis_. …
Matched Salts cas: … 83881-52-1
Matched Products: … H-E-B Allergy Relief ... CETIRIZIN HEXAL B ALLERGIE ... CETIRIZIN HEXAL SAFT B ALL …
Benperidol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders, among others.
Approved
Investigational
Matched Iupac: … 1-(4-fluorophenyl)-4-[4-(2-hydroxy-1H-1,3-benzodiazol-1-yl)piperidin-1-yl]butan-1-one …
Matched Products: … BENPERIDOL-NEURAX 2 MG …
Macitentan is a dual endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension (PAH). It was first approved by the FDA in 2013. Macitentan differs from its predecessor bosentan in part due to its lower risk of hepatotoxicity. A combination product (Opsynvi) comprising macitentan and tadalafil was approved...
Approved
Matched Iupac: … {[5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl]sulfamoyl}(propyl)amine …
Matched Description: … Macitentan is a dual endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension ... A combination product (Opsynvi) comprising macitentan and [tadalafil] was approved in Canada in October …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Endothelin A Receptor Antagonists ... Endothelin B Receptor Antagonists …
Pantoprazole is a first-generation proton pump inhibitor (PPI) used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison (ZE) Syndrome. It can also be...
Approved
Matched Iupac: … 6-(difluoromethoxy)-2-[(3,4-dimethoxypyridin-2-yl)methanesulfinyl]-1H-1,3-benzodiazole …
Matched Description: … As the binding of pantoprazole to the (H+, K+)-ATPase enzyme is irreversible and new enzyme needs to ... step in gastric acid production by covalently binding to sulfhydryl groups of cysteines found on the (H+ ... rebound effect and a short term increase in hypersecretion. …
Matched Salts cas: … 164579-32-2
Matched Categories: … 2-Pyridinylmethylsulfinylbenzimidazoles …
Matched Products: … Pantoprazol A-Med 20 mg magensaftresistente Tabletten ... Pantoprazol A-Med 40 mg magensaftresistente Tabletten ... flakon+ 1 adet çözücü içeren flakon …
Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. Mannitol elevates blood plasma osmolality, resulting in enhanced flow of water from tissues, including the brain and cerebrospinal fluid, into interstitial fluid and plasma. As a...
Approved
Investigational
Matched International brands: … Mannisol A
Matched Description: … Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar ... As a result, cerebral edema, elevated intracranial pressure, and cerebrospinal fluid volume and pressure ... established; the promotion of urinary excretion of toxic substances; as an Antiglaucoma agent; and as a
Matched Mixtures name: … Cystosol W 3% Hexitols …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … B. BRAUN OSMOFUNDIN 20% ... B. BRAUN OSMOFUNDIN 10% (500ML) ... B. Braun Mannitol 20% Solution for Infusion …
Atropine is an alkaloid originally synthesized from Atropa belladonna. It is a racemic mixture of d-and l-hyoscyamine, of which only l-hyoscyamine is pharmacologically active.[A251670,L42835] Atropine is generally available as a sulfate salt and can be administered by intravenous, subcutaneous, intramuscular, intraosseous, endotracheal and ophthalmic methods. Oral atropine is only available...
Approved
Vet approved
Matched Iupac: … (1R,3S,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 3-hydroxy-2-phenylpropanoate …
Matched Description: … It is a racemic mixture of d-and l-hyoscyamine, of which only l-hyoscyamine is pharmacologically active ... [A251660,L42840] Atropine is a competitive, reversible antagonist of muscarinic receptors that blocks ... [A251670,L42835] Atropine is generally available as a sulfate salt and can be administered by intravenous …
Matched Salts cas: … 55-48-1
Matched Mixtures name: … B-Donna ... PHARMANIAGA DIPHENOXYLATE A TABLET …
Matched Products: … N/a ... ATROPİN SÜLFAT 1/2 MG AMPUL , 10 ADET ... ATROPIN SÜLFAT 1/2 MG/1 ML ENJEKSİYONLUK ÇÖZELTİ, 10 AMPUL …
Gemtuzumab ozogamicin is a recombinant humanized IgG4 kappa antibody which is conjugated with calicheamicin derivative, a cytotoxic antitumor antibiotic isolated from fermentation of Micromonospora echinospora ssp. calichensis. Gemtuzumab ozogamicin has approximately 50% of the antibody loaded with 4-6 moles calicheamicin per mole of antibody [FDA Label]. The antibody is specifically...
Approved
Investigational
Matched Description: … On September 1 2017, gemtuzumab ozogamicin was again approved for the treatment of adults with newly ... It is also indicated for the treatment of patients aged 2 years and older with CD33-positive AML who ... The antibody is specifically directed against the CD33 antigen present on leukemic myeloblasts in most …
Matched Products: … MYLOTARG 5 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ, 1 FLAKON …
Atazanavir (formerly known as BMS-232632) is an antiretroviral drug of the protease inhibitor (PI) class. Like other antiretrovirals, it is used to treat infection of human immunodeficiency virus (HIV). Atazanavir is distinguished from other PIs in that it can be given once daily (rather than requiring multiple doses per day)...
Approved
Investigational
Matched Iupac: … methyl N-[(1S)-1-{N'-[(2S,3S)-2-hydroxy-3-[(2S)-2-[(methoxycarbonyl)amino]-3,3-dimethylbutanamido]-4- ... phenylbutyl]-N'-{[4-(pyridin-2-yl)phenyl]methyl}hydrazinecarbonyl}-2,2-dimethylpropyl]carbamate …
Matched Description: … Like other antiretrovirals, it is used to treat infection of human immunodeficiency virus (HIV). …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
HIV/AIDS remains an area of concern despite the introduction of numerous successful therapies, mainly due to the emergence of multidrug resistance and patient difficulty in adhering to treatment regimens.[A244170, A244175] Lenacapavir is a first-in-class capsid inhibitor that demonstrates picomolar HIV-1 inhibition as a monotherapy in vitro, little to no cross-resistance...
Approved
Investigational
Matched Iupac: … N-[(1S)-1-{3-[4-chloro-3-methanesulfonamido-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl]-6-(3-methanesulfonyl ... -3-methylbut-1-yn-1-yl)pyridin-2-yl}-2-(3,5-difluorophenyl)ethyl]-2-[(2S,4R)-5,5-difluoro-9-(trifluoromethyl ... )-7,8-diazatricyclo[4.3.0.0^{2,4}]nona-1(6),8-dien-7-yl]acetamide …
Matched Description: … [A244170, A244175] Lenacapavir is a first-in-class capsid inhibitor that demonstrates picomolar HIV-1 ... inhibition as a monotherapy _in vitro_, little to no cross-resistance with existing antiretroviral agents …
Matched Categories: … Human Immunodeficiency Virus 1 Capsid Inhibitor ... Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 1-Ring …
Dequalinium is an antibacterial agent with multi-targeted actions. It also possesses antifungal, antiparasitic, antiviral, anticancer, and neuroprotective properties. It is a quaternary ammonium compound, as it consists of an amphipathic cation with two aminoquinaldinium rings at both ends of a long hydrophobic hydrocarbon chain. Due to its flexible structure, dequalinium...
Approved
Investigational
Matched Synonyms: … 1,1'-(1,10-Decanediyl)bis(4-amino-2-methylquinolinium) dichloride …
Matched Iupac: … 4-amino-1-[10-(4-amino-2-methylquinolin-1-ium-1-yl)decyl]-2-methylquinolin-1-ium …
Matched Description: … two aminoquinaldinium rings at both ends of a long hydrophobic hydrocarbon chain. ... [A249255] It is a quaternary ammonium compound,[L42190] as it consists of an amphipathic cation with …
Matched Salts cas: … 4028-98-2
Matched Mixtures name: … Eucillin "B" - Salbe …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.
Approved
Matched Iupac: … N-[(1S)-3-amino-1-{[(1S,2R)-1-{[(1S)-3-amino-1-{[(6R,9S,12R,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3- ... [(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan ... -21-yl]carbamoyl}propyl]carbamoyl}-2-hydroxypropyl]carbamoyl}propyl]-5-methylheptanamide …
Matched Description: … It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes ... Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally. …
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
A fluorinated cytosine analog that is used as an antifungal agent.
Approved
Investigational
Matched Iupac: … 4-amino-5-fluoro-1,2-dihydropyrimidin-2-one …
Matched Description: … A fluorinated cytosine analog that is used as an antifungal agent. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
This is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (pyridoxamine).
Approved
Investigational
Nutraceutical
Matched Synonyms: … 3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinecarboxaldehyde ... 3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde 5-phosphate …
Matched Iupac: … [(4-formyl-5-hydroxy-6-methylpyridin-3-yl)methoxy]phosphonic acid …
Matched Description: … This is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters …
Matched Salts cas: … 41468-25-1
Matched Categories: … Vitamin B Complex ... Heterocyclic Compounds, 1-Ring …
Antihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential component of the coagulation cascade. Antihemophilic factor is manufactured with reduced amounts of von Willebrand Factor antigen (VWF:Ag) and purified from extraneous plasma-derived...
Approved
Matched Description: … Antihemophilic factor is manufactured with reduced amounts of von Willebrand Factor antigen (VWF:Ag) ... technology and is identical in sequence to endogenously produced Factor VIII, but does not contain the B-domain ... The final purified concentrate contains albumin as a stabilizer.[L1053]. …
Matched Mixtures name: … BERIPLAST-P COMBI SET 3 ML TROMBİN ÇÖZELTİSİ VE 1 ML FİBRİNOJEN ÇÖZELTİSİ İÇEREN FİBRİN YAPIŞTIRICI ... BERIPLAST-P COMBI SET 1 ML TROMBİN ÇÖZELTİSİ VE 1 ML FİBRİNOJEN ÇÖZELTİSİ İÇEREN FİBRİN YAPIŞTIRICI ... IMMUNATE 500 IU/375 IU IV INFUZYONLUK TOZ ICEREN FLAKON, 1 ADET …
Matched Categories: … Hemophilia A
Matched Products: … +1 ADET ÇÖZÜCÜ İÇEREN ENJEKTÖR ... FACTOR VIII 500 IU FLAKON, 1 ADET ... OCTANATE 500 IU IV ENJEKSIYON IÇIN TOZ IÇEREN FLAKON, 1 ADET …
Binimetinib, also known as Mektovi, is a potent and selective oral mitogen-activated protein kinase 1/2 (MEK 1/2) inhibitor which is combined with Encorafenib.[A34275,L3335] On June 27, 2018, the Food and Drug Administration approved the combination of Encorafenib and binimetinib (BRAFTOVI and MEKTOVI, from Array BioPharma Inc.) in combination for patients...
Approved
Investigational
Matched Iupac: … 5-[(4-bromo-2-fluorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-1,3-benzodiazole-6-carboxamide …
Matched Description: … 1/2 (MEK 1/2) inhibitor which is combined with [Encorafenib]. ... Binimetinib, also known as _Mektovi_, is a potent and selective oral mitogen-activated protein kinase ... [A34275,L3335] On June 27, 2018, the Food and Drug Administration approved the combination of [Encorafenib …
Matched Categories: … MAP Kinase Kinase 1, antagonists & inhibitors ... Heterocyclic Compounds, 2-Ring ... MAP Kinase Kinase 2, antagonists & inhibitors ... UGT1A1 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index …
A topical anti-inflammatory glucocorticoid used in dermatoses, skin allergies, psoriasis, etc.
Approved
Matched Synonyms: … 9alpha-fluoro-16alpha-methyl-delta(1)-corticosterone …
Matched Iupac: … (1S,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-10-hydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H,2H,3H ... ,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one …
Matched Description: … A topical anti-inflammatory glucocorticoid used in dermatoses, skin allergies, psoriasis, etc. …
An antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564). Dacarbazine with Oblimersen is in clinical trials for the treatment of malignant melanoma.
Approved
Investigational
Matched Synonyms: … 4-(3,3-dimethyl-1-triazeno)imidazole-5-carboxamide ... 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide ... 4-(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide …
Matched Iupac: … 5-[(1E)-3,3-dimethyltriaz-1-en-1-yl]-1H-imidazole-4-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic Index …
Matched Products: … TREXTECH® 200 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …
Fomivirsen is a antisense 21 mer phosphorothioate oligonucleotide. It is an antiviral agent that was used in the treatment of cytomegalovirus retinitis (CMV) in immunocompromised patients, including those with AIDS. As a complementary nucleotide to the messenger RNA of the major immediate-early region proteins of human cytomegalovirus, it disrupts the...
Approved
Investigational
Withdrawn
Matched Description: … cytomegalovirus, it disrupts the replication of the virus through an antisense mechanism [L1428]. ... Fomivirsen is a antisense 21 mer phosphorothioate oligonucleotide. ... As a complementary nucleotide to the messenger RNA of the major immediate-early region proteins of human …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).[label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation...
Approved
Vet approved
Matched Synonyms: … [2-(2,6-dichloroanilino)phenyl]acetic acid ... 2-((2,6-dichlorophenyl)amino)benzeneacetic acid …
Matched Iupac: … 2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid …
Matched Description: … [label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins ... Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID). ... other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation from a
Matched Mixtures name: … Calcipotriene 0.005% / Diclofenac Sodium 3% / Hyaluronic Acid Sodium Salt 2% / Niacinamide 2% ... Diclo Gel 1% Pak ... DICLOVITH-B
Matched Categories: … Cyclooxygenase-2 (COX-2) Inhibitors ... Non COX-2 selective NSAIDS …
Matched Products: … 3-A OFTENO ... 3- A OFTENO ... VOLTAREN %1 FLASTER, 2 ADET …
Displaying drugs 376 - 400 of 6246 in total