Displaying drugs 376 - 400 of 15247 in total
Cocaine
An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of...
Approved
Illicit
Matched Description: … It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in ... Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism ... It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse …
Matched Salts cas: … 53-21-4 …
Matched Products: … PMS-cocaine Hydrochloride Topical Sol 4% …
Matched Salts cas: … 53-21-4 …
Matched Products: … PMS-cocaine Hydrochloride Topical Sol 4% …
Beractant
Beractant is a pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants. Considered a natural source of surfactant as it is made from bovine lung extract, beractant contains a mixture of phospholipids, neutral lipids, fatty acids, and surfactant-associated proteins such as SP-B and SP-C. The...
Approved
Matched Description: … Beractant is a pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in ... a reduced incidence of pneumothorax and reduced mortality. ... Considered a natural source of surfactant as it is made from bovine lung extract, beractant contains …
Matched Products: … SURVANTA ® 4 ML …
Matched Products: … SURVANTA ® 4 ML …
Nitroprusside
Nitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles and venules (venules more than arterioles). Nitroprusside is often administered intravenously to patients who are experiencing a hypertensive emergency.
Approved
Investigational
Matched Description: … Nitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles ... Nitroprusside is often administered intravenously to patients who are experiencing a hypertensive emergency …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Sodium Nitroprusside In 0.9% Sodium Chloride …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Sodium Nitroprusside In 0.9% Sodium Chloride …
Aluminum chloride
Aluminum chloride is a chemical compound with the chemical formula AlCl3. When contaminated with iron chloride, it often displays a yellow color compared to the white pure compound. It is used in various chemical applications as a Lewis base, with anhydrous aluminium trichloride being the most commonly used Lewis acid....
Approved
Investigational
Matched Description: … It is used in various chemical applications as a Lewis base, with anhydrous aluminium trichloride being ... Aluminum chloride is a chemical compound with the chemical formula AlCl3. ... When contaminated with iron chloride, it often displays a yellow color compared to the white pure compound …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Hemox A …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Hemox A …
Melphalan
Melphalan is a nitrogen mustard or bischloroethylamine type alkylating agent. It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard.[A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. It is also used for high-conditioning before hematopoietic stem...
Approved
Matched Synonyms: … 4-(Bis(2-chloroethyl)amino)-L-phenylalanine …
Matched Iupac: … (2S)-2-amino-3-{4-[bis(2-chloroethyl)amino]phenyl}propanoic acid …
Matched Description: … [L40928] It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group ... Melphalan is a nitrogen mustard or bischloroethylamine type alkylating agent. ... [A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. …
Matched Iupac: … (2S)-2-amino-3-{4-[bis(2-chloroethyl)amino]phenyl}propanoic acid …
Matched Description: … [L40928] It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group ... Melphalan is a nitrogen mustard or bischloroethylamine type alkylating agent. ... [A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. …
Penicillium chrysogenum var. chrysogenum
Penicillium chrysogenum var. chrysogenum is a fungus which can provoke allergic reactions. Penicillium chrysogenum var. chrysogenum extract is used in allergenic testing.
Approved
Matched Description: … Penicillium chrysogenum var. chrysogenum extract is used in allergenic testing. ... Penicillium chrysogenum var. chrysogenum is a fungus which can provoke allergic reactions. …
Matched Mixtures name: … Molds - Mold Mix 4 ... Molds - Mold Mix 4 ... Molds - Mold Mix 4 …
Matched Mixtures name: … Molds - Mold Mix 4 ... Molds - Mold Mix 4 ... Molds - Mold Mix 4 …
Olopatadine
Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating inflammatory and allergic reactions. It is a structural analog of doxepin, which has a minimal anti-allergic activity. Olopatadine works by blocking the effects of histamine, which is a primary inflammatory mediator that causes inflammatory and...
Approved
Matched Description: … Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating ... [L6790] Olopatadine works by blocking the effects of histamine, which is a primary inflammatory mediator ... [A1172] In comparison to other anti-allergenic ophthalmic medications, olopatadine displays a good comfort …
Matched Products: … OLO-A-DAY ... Pataday Twice A Day Relief …
Matched Products: … OLO-A-DAY ... Pataday Twice A Day Relief …
Atomoxetine
Atomoxetine is a selective norepinephrine (NE) reuptake inhibitor used for the treatment of attention deficit hyperactivity disorder (ADHD). Also known as the marketed product Strattera, atomoxetine is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve developmentally inappropriate symptoms associated with ADHD including distractibility, short attention...
Approved
Matched Description: … In particular, increased dopamine in key areas caused by these stimulant medications is associated with ... noradrenergic and dopaminergic pathways plays a critical role in suboptimal executive functioning within ... adults and children as recommended by CADDRA (Canadian ADHD Resource Alliance). …
Matched Products: … STRATTERA 4 MG/ML ORAL ÇÖZELTI ... ATTEX 4 MG/ML ORAL ÇÖZELTİ, 100 ML ... SETİNOX 4 MG/ML ORAL ÇÖZELTİ, 100 ml …
Matched Products: … STRATTERA 4 MG/ML ORAL ÇÖZELTI ... ATTEX 4 MG/ML ORAL ÇÖZELTİ, 100 ML ... SETİNOX 4 MG/ML ORAL ÇÖZELTİ, 100 ml …
Aspergillus fumigatus
Aspergillus fumigatus is a fungus which can provoke allergic reactions. Aspergillus fumigatus extract is used in allergenic testing.
Approved
Matched Description: … Aspergillus fumigatus extract is used in allergenic testing. ... Aspergillus fumigatus is a fungus which can provoke allergic reactions. …
Matched Mixtures name: … Molds - Mold Mix 4 ... Molds - Mold Mix 4 ... Molds - Mold Mix 4 …
Matched Mixtures name: … Molds - Mold Mix 4 ... Molds - Mold Mix 4 ... Molds - Mold Mix 4 …
Talimogene laherparepvec
Talimogene laherparepvec is an oncolytic treatment used in local treatment of unresectable cutaneous, subcutaneous, and nodal lesions in patients with recurrent melanoma. It is a genetically administered herpes simplex virus 1 (HSV-1) that expresses human cytokine granulocyte-macrophage colony stimulating factor (GM-CSF) with antitumor and immune-stimulating activities. It specifically replicates within...
Approved
Experimental
Investigational
Matched Description: … It was approved by the FDA in 2015 under the market name Imlygic. ... It is a genetically administered herpes simplex virus 1 (HSV-1) that expresses human cytokine granulocyte-macrophage ... subcutaneous, and nodal lesions in patients with recurrent melanoma. …
Matched Categories: … Antineoplastic cell and gene therapy …
Matched Categories: … Antineoplastic cell and gene therapy …
Baloxavir marboxil
Baloxavir marboxil is an antiviral drug used to treat influenza. More specifically, it is a first-in-class cap-dependent endonuclease inhibitor that works to block influenza virus proliferation.[A39895, A251755] It is a prodrug of baloxavir with an improved absorption profile than its active metabolite due to the addition of a phenolic hydroxyl...
Approved
Investigational
Matched Description: … by the US approval in October, 2018. ... More specifically, it is a first-in-class cap-dependent endonuclease inhibitor that works to block influenza ... [L4779] It was also approved by the European Commission on January 7, 2021.[L45241] …
Matched Products: … XOFLUZA 20 MG FİLM KAPLI TABLET, 4 ADET …
Matched Products: … XOFLUZA 20 MG FİLM KAPLI TABLET, 4 ADET …
Migalastat
Fabry disease is a rare, progressive genetic disorder characterized by a defective GLA gene that causes a deficiency in the enzyme alpha-Galactosidase A (alpha-Gal A). This enzyme is responsible for breaking down glycosphingolipid substrate that, when deficient in patients with Fabry disease, builds up in the blood vessels, the kidneys,...
Approved
Investigational
Matched Description: … Fabry disease is a rare, progressive genetic disorder characterized by a defective GLA gene that causes ... [L47036,L47057,L4274,L4278] In these patients, migalastat works by stabilizing the body’s dysfunctional ... a deficiency in the enzyme alpha-Galactosidase A (alpha-Gal A). …
Matched Categories: … Alpha-Galactosidase A (alpha-Gal A) Pharmacological Chaperones …
Matched Categories: … Alpha-Galactosidase A (alpha-Gal A) Pharmacological Chaperones …
Indacaterol
Indacaterol is a novel, ultra-long-acting, rapid onset β(2)-adrenoceptor agonist developed for Novartis for the once-daily management of asthma and chronic obstructive pulmonary disease. It was approved by the European Medicines Agency (EMA) on 30 November 2009 and by the FDA on 1 July 2011. It is marketed in Europe as...
Approved
Matched Description: … It is marketed in Europe as Onbrez and in America as Arcapta Neohaler. ... It was approved by the European Medicines Agency (EMA) on 30 November 2009 and by the FDA on 1 July 2011 ... Indacaterol is also a chiral molecule but only the pure R-enantiomer is dispensed. …
Agalsidase beta
Agalsidase beta is a recombinant human α-galactosidase A similar to agalsidase alfa. While patients generally do not experience a clinically significant difference in outcomes between the two drugs, some patients may experience greater benefit with agalsidase beta.[A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa,...
Approved
Investigational
Matched Description: … a contamination event in 2009. ... While patients generally do not experience a clinically significant difference in outcomes between the ... Agalsidase beta is a recombinant human α-galactosidase A similar to [agalsidase alfa]. …
Topiramate
Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults.[A188309,L10544,L43478] Since 2012, the extended-release formulation has been approved in combination with phentermine for chronic weight management therapy...
Approved
Matched Description: … [A175249] It was initially approved by the FDA in 1996. ... chemical structure containing a sulfamate, and 40% of its mass accounted for by oxygen. ... [A175249] Interestingly, topiramate was discovered by chance when attempts were made to formulate a novel …
Matched Salts cas: … 1246279-00-4 …
Matched Products: … Topamax 15 mg Granulat in Kapseln ... Topamax 25 mg Granulat in Kapseln ... Topamax 50 mg Granulat in Kapseln …
Matched Salts cas: … 1246279-00-4 …
Matched Products: … Topamax 15 mg Granulat in Kapseln ... Topamax 25 mg Granulat in Kapseln ... Topamax 50 mg Granulat in Kapseln …
Palivizumab
Humanized monoclonal antibody (IgG1k) produced by recombinant DNA technology, directed to an epitope in the A antigenic site of the F protein of respiratory syncytial virus (RSV). Synagis is a composite of human (95%) and murine (5%) antibody sequences. The human heavy chain sequence was derived from the constant domains...
Approved
Investigational
Matched Description: … in the A antigenic site of the F protein of respiratory syncytial virus (RSV). ... K104 withJk-4. ... lightchain sequence was derived from the constant domain of Ck and the variable framework regions of the VL gene …
Milrinone
Heart failure is a multifactorial condition that affects roughly 1-2% of the adult population. Often the result of long-term myocardial ischemia, cardiomyopathy, or other cardiac insults, heart failure results from an inability of the heart to perfuse peripheral tissues with sufficient oxygen and metabolites, resulting in complex systemic pathologies. Heart...
Approved
Matched Description: … Heart failure is underpinned by numerous physiological changes, including alteration in β-adrenergic ... [A228333] As a PDE-III inhibitor, milrinone results in increased cAMP levels and improves cardiac function ... ® by Sanofi-Aventis US before being discontinued. …
Matched Mixtures name: … Milrinone Lactate in Dextrose …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Milrinone Lactate in Dextrose …
Matched Mixtures name: … Milrinone Lactate in Dextrose …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Milrinone Lactate in Dextrose …
Ginkgo biloba
Ginkgo biloba extract contains a group of terpene lactones (notably, ginkgolides and diterpenes) and ginkgo flavone glycosides (notably, ginkgetin, bilobetin, and sciadopitysin) that have antioxidant and vasoactive properties. Most of the studies that investigate the effect of ginkgo biloba use the standardized extract of Ginkgo biloba (EGb) 761 (EGb761), which...
Approved
Investigational
Nutraceutical
Matched Description: … a German pharmaceutical company in 1964. ... _Ginkgo biloba_ is found in a number of homeopathic and over-the-counter herbal products and dietary ... [A232384] _Ginkgo biloba_ was investigated in preliminary studies for a variety of therapeutic purposes …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Products: … EXTRACTO DE GINKO BILOBA AL 24 % EQUIVALENTE A 9.6 MG DE GLICOSIDOS FLAVONOIDES. …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Products: … EXTRACTO DE GINKO BILOBA AL 24 % EQUIVALENTE A 9.6 MG DE GLICOSIDOS FLAVONOIDES. …
Melatonin
Melatonin is a biogenic amine that is found in animals, plants and microbes. Aaron B. Lerner of Yale University is credited for naming the hormone and for defining its chemical structure in 1958. In mammals, melatonin is produced by the pineal gland. The pineal gland is small endocrine gland, about...
Approved
Nutraceutical
Vet approved
Matched Description: … In mammals, melatonin is produced by the pineal gland. ... In particular, melatonin regulates the sleep-wake cycle by chemically causing drowsiness and lowering ... Melatonin is a biogenic amine that is found in animals, plants and microbes. Aaron B. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Mellozzan 4 mg Tabletten …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Mellozzan 4 mg Tabletten …
Velaglucerase alfa
Velaglucerase alfa is a gene-activated human recombinant glucocerebrosidase used for the treatment of Type 1 Gaucher disease, caused by a deficiency of the lysosomal enzyme glucocerebrosidase. Additionally, Velaglucerase alfa has also been investigated for use in Type 3 Gaucher disease.
Approved
Investigational
Matched Description: … Type 1 Gaucher disease, caused by a deficiency of the lysosomal enzyme glucocerebrosidase. ... Velaglucerase alfa is a gene-activated human recombinant glucocerebrosidase used for the treatment of ... Additionally, Velaglucerase alfa has also been investigated for use in Type 3 Gaucher disease. …
Yellowfin tuna
Yellowfin tuna allergenic extract is used in allergenic testing.
Approved
Matched Description: … Yellowfin tuna allergenic extract is used in allergenic testing. …
Leuprolide
Leuprolide is a synthetic 9-residue peptide analogue of gonadotropin-releasing hormone (GnRH). Unlike the endogenous decapeptide GnRH, leuprolide contains a single D-amino acid (D-leucyl) residue, which helps to increase its circulating half-life from three to four minutes to approximately three hours. As a GnRH mimic, leuprolide is capable of binding to...
Approved
Investigational
Matched Iupac: … hydroxyphenyl)propanamido]-4-methylpentanamido]-4-methylpentanamido]pentanoyl]-N-ethylpyrrolidine-2-carboxamide ... -1-[(2S)-5-carbamimidamido-2-[(2S)-2-[(2R)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-4- ... )-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4- …
Matched Description: … tradename Lupron™ by Abbvie Endocrine Inc. ... [A203126, A203132] Leuprolide was first approved in 1985 as a daily subcutaneous injection under the ... Leuprolide is a synthetic 9-residue peptide analogue of gonadotropin-releasing hormone (GnRH). …
Matched Products: … LUPRON ® DEPOT 11.25 MG POLVO LIOFILIOZADO PARA RECONSTITUIR A SUSPENSIÓN INYECTABLE …
Matched Description: … tradename Lupron™ by Abbvie Endocrine Inc. ... [A203126, A203132] Leuprolide was first approved in 1985 as a daily subcutaneous injection under the ... Leuprolide is a synthetic 9-residue peptide analogue of gonadotropin-releasing hormone (GnRH). …
Matched Products: … LUPRON ® DEPOT 11.25 MG POLVO LIOFILIOZADO PARA RECONSTITUIR A SUSPENSIÓN INYECTABLE …
Permethrin
A pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. It is a yellow to light orange-brown, low melt-ing solid or viscous liquid.
Approved
Investigational
Matched Description: … A pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. ... It is a yellow to light orange-brown, low melt-ing solid or viscous liquid. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … A Scabs ... A-LICES LOTION 1%w/w …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … A Scabs ... A-LICES LOTION 1%w/w …
Capsaicin
Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements. Capsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical formulations. The most recent...
Approved
Matched Iupac: … (6E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide …
Matched Description: … Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, ... Capsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical ... and patch preparations of various strengths; however, it may also be found in some dietary supplements …
Matched Mixtures name: … Tianhe Gutong Tiegao (in Polyisobutylene Carrier) ... 1st Medxpatch With Lidocaine 4% ... 1st Medxpatch With Lidocaine 4%-rx …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Products: … Antiphlogistine Rub A-535 Capsaicin Gel ... Antiphlogistine Rub A-535 Capsaicin Liquid …
Matched Description: … Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, ... Capsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical ... and patch preparations of various strengths; however, it may also be found in some dietary supplements …
Matched Mixtures name: … Tianhe Gutong Tiegao (in Polyisobutylene Carrier) ... 1st Medxpatch With Lidocaine 4% ... 1st Medxpatch With Lidocaine 4%-rx …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Products: … Antiphlogistine Rub A-535 Capsaicin Gel ... Antiphlogistine Rub A-535 Capsaicin Liquid …
Methylphenidate
Methylphenidate is a central nervous system stimulant used most commonly in the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) and for narcolepsy. Also known as the marketed products Ritalin, Concerta, or Biphentin, methylphenidate is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve the following group of developmentally...
Approved
Investigational
Matched Description: … gene (DAT1), the D4 receptor gene (DRD-4), and/or the D2 receptor gene that may be at least partly overcome ... by the dopaminergic effects of methylphenidate, suggesting a possible mode of action. ... [A631] OROS is comprised of an osmotically active trilayer core surrounded by a semipermeable membrane …
Matched Salts cas: … 23655-65-4 …
Matched Salts cas: … 23655-65-4 …
Displaying drugs 376 - 400 of 15247 in total