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Displaying drugs 4026 - 4050 of 9536 in total

Icaritin

Icaritin has been used in trials studying the treatment of Solid Tumors, Metastatic Breast Cancer, and Hepatocellular Carcinoma (HCC).
Investigational
Matched Iupac: … 3,5,7-trihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4H-chromen-4-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

4-methyl-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-2-amine

Experimental
Matched Name: … 4-methyl-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-2-amine …
Matched Iupac: … 4-methyl-5H,7H,8H-thiopyrano[4,3-d]pyrimidin-2-amine …

Murizatoclax

Investigational
Matched Iupac: … (1S,3'R,6'R,7'R,8'E,11'S,12'R)-7'-{[(9aR)-octahydro-1H-pyrido[1,2-a]pyrazin-2-yl]methyl}-6-chloro-7'- ... [14.7.2.0^{3,6}.0^{19,24}]pentacosane]-8',16',18',24'-tetraene-13',13',15'-trione ... methoxy-11',12'-dimethyl-3,4-dihydro-2H-20'-oxa-13'lambda6-thia-1',14'-diazaspiro[naphthalene-1,22'-tetracyclo …

Doranidazole

Investigational
Matched Synonyms: … (2rs,3sr)-3-((2-nitroimidazol-1-yl)methoxy)butane-1,2,4-triol ... 1,2,4-butanetriol, 3-((2-nitro-1h-imidazol-1-yl)methoxy)-, (2r,3s)-rel- …
Matched Iupac: … (2R,3S)-3-[(2-nitro-1H-imidazol-1-yl)methoxy]butane-1,2,4-triol …

DG031

DG031, deCODE genetics's lead compound, is being developed for the prevention of myocardial infarction, or heart attack.
Investigational

KB002

KB002 is an engineered human IgG1k antibody engineered human. It is developed for the treatment of autoimmune diseases, initially rheumatoid arthritis.
Investigational

PRX-07034

Investigational
Matched Iupac: … N-[1-(5-chloro-2,3-dimethoxyphenyl)ethyl]-2-methanesulfonyl-5-(piperazin-1-yl)aniline hydrochloride …

GLPG-0259

GLPG-0259 is under investigation in clinical trial NCT01024517 (GLPG0259 Solid Formulation Bioavailability and Food Effect).
Investigational
Matched Iupac: … 4-[8-({4-[(1S,4S)-5-(propan-2-yl)-2,5-diazabicyclo[2.2.1]heptan-2-yl]phenyl}amino)-[1,2,4]triazolo[1,5 ... -a]pyrazin-5-yl]furan-2-carboxamide …

PR006

PR006 is a non-replicating recombinant adeno-associated virus serotype 9 containing the progranulin gene. It is being investigated for the treatment of dementia.
Investigational

PBR-06 F-18

Investigational
Matched Synonyms: … Acetamide, n-((2,5-dimethoxyphenyl)methyl)-2-(fluoro-18f)-n-(2-phenoxyphenyl)- …
Matched Iupac: … N-[(2,5-dimethoxyphenyl)methyl]-2-(¹⁸F)fluoro-N-(2-phenoxyphenyl)acetamide …

NRC-AN-019

Investigational
Matched Synonyms: … 3,5-BIS(TRIFLUOROMETHYL)-N-(4-METHYL-3-((4-(PYRIDIN-3-YL)PYRIMIDIN-2-YL)AMINO)PHENYL)BENZAMIDE ... (3,5-BIS TRIFLUOROMETHYL)-N-(4-METHYL-3-(4-PYRIDIN-3YL-PYRIMIDIN-2-YL AMINO) PHENYL)BENZAMIDE ... (3,5-Bis Trifluoromethyl)-N-[4-Methyl-3-(4-Pyridin-3Yl-Pyrimidin-2-Yl Amino) Phenyl] Benzamide …

SNS01-T

SNS01-T is a gene therapy nanoparticle. It is composed of three components: a B cell-specific plasmid expressing eIF5AK50R; an siRNA that targets the native eIF5A that promotes growth/anti-apoptosis of cancer cells; and polyethylenimine.
Investigational

RR001

RR001 is an investigational gene therapy consisting of autologous human adipose perivascular stromal cells genetically modified to secrete soluble tumour necrosis factor-related apoptosis-inducing ligand (AD-PC sTRAIL).
Investigational

TTAX01

TTAX01 is a cryopreserved human umbilical cord product being developed by TissueTech.
Investigational

ALMB-0166

ALMB-0166 is a umanized connexin 43 (Cx43) monoclonal antibody being investigated for the treatment of acute spinal cord injury. It was granted FDA orphan designation in November 2018.
Investigational

NX001

Investigational

EB003

EB003 is a CRISPR-based sequence-specific antimicrobial (SSAM) targeted against shiga toxin-producing E. coli.
Investigational

PBGM01

PBGM01 is a non-replicating recombinant adeno-associated virus serotype hu68 vector, which contains human GLB1 transgene encoding the galactosidase beta 1 enzyme.
Investigational

VGB-R04

VGB-R04 is an adeno-associated viral vector delivering human FIX Padua gene.
Investigational

Ivuxolimab

Ivuxolimab is under investigation in clinical trial NCT02554812 (A Study of Avelumab in Combination With Other Cancer Immunotherapies in Advanced Malignancies (JAVELIN Medley)).
Investigational

STX-107

Investigational
Matched Synonyms: … 3-fluoro-5-[5-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridin-2-yl]benzonitrile ... 3-Fluoro-5-(5-((2-methylthiazol-4-yl)ethynyl)pyridin-2-yl)benzonitrile …
Matched Iupac: … 3-fluoro-5-{5-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridin-2-yl}benzonitrile …

NSI-189

NSI-189 is under investigation in clinical trial NCT02695472 (Study of NSI-189 for Major Depressive Disorder).
Investigational
Matched Iupac: … 3-(4-benzylpiperazine-1-carbonyl)-N-(3-methylbutyl)pyridin-2-amine …

(2R,3R,4R,5R)-3,4-Dihydroxy-N,N'-bis[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-2,5-bis(2-phenylethyl)hexanediamide

Experimental
Matched Name: … (2R,3R,4R,5R)-3,4-Dihydroxy-N,N'-bis[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-2,5-bis(2-phenylethyl …
Matched Iupac: … (2R,3R,4R,5R)-3,4-dihydroxy-N,N'-bis[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-2,5-bis(2-phenylethyl …

Allylestrenol

A synthetic steroid with progestational activity. It is widely marketed throughout Europe, including Russia and many other European countries, and is also available in Japan, Hong Kong, India, Bangladesh, Indonesia, and much of Southeast Asia, though notably not in the United States or Canada.
Experimental
Matched Synonyms: … 3-deketo-17α-allyl-19-nortestosterone …
Matched Iupac: … (1R,3aS,3bR,9aR,9bS,11aS)-11a-methyl-1-(prop-2-en-1-yl)-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H …

(3aS)-3a-hydroxy-5-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one

Experimental
Displaying drugs 4026 - 4050 of 9536 in total