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Displaying drugs 401 - 425 of 1131 in total
Melphalan is a nitrogen mustard or bischloroethylamine type alkylating agent. It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard.[A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. It is also used for high-conditioning before hematopoietic stem...
Approved
Matched Synonyms: … 3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine ... 3-p-(Di(2-chloroethyl)amino)-phenyl-L-alanine ... L-3-(p-(Bis(2-chloroethyl)amino)phenyl)alanine
Matched Description: … [A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. ... [L40928] It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group …
Matched Salts name: … Melphalan hydrochloride
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Melphalan Hydrochloride ... Melphalan hydrochloride
A sulfur containing essential amino acid that is important in many body functions. It is a chelating agent for heavy metals.
Approved
Nutraceutical
Matched Synonyms: … Methionine ... L-Methionin ... L-Methionine
Matched Name: … Methionine
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Men's Biomultiple Vitamin and Mineral Supplement …
Matched Salts name: … Methionine hydrochloride
Matched Categories: … Amino Acids, Peptides, and Proteins ... methionine
Investigational
Matched Synonyms: … Immunoglobulin G4 (52-glycine, 57-phenylalanine, 227-proline, 233-alanine, 234-alanine, 446-alanine), …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Hexaminolevulinate is an optical imaging drug. In solution form it is instilled intravesically for use with photodynamic blue light cystoscopy as an adjunct to white light cystoscopy. On May 28, 2010, the U.S. Food and Drug Administration (FDA) granted approval for hexaminolevulinate hydrochloride (Cysview for Intravesical Solution, Photocure ASA), as...
Approved
Matched Synonyms: … Hexyl 5-amino-4-oxopentanoate hydrochloride ... Hexyl(5-amino-4-oxopentanoat)-hydrochlorid ... Pentanoic acid, 5-amino-4-oxo-, hexyl ester, hydrochloride
Matched Description: … Food and Drug Administration (FDA) granted approval for hexaminolevulinate hydrochloride (Cysview for …
Matched Salts name: … Hexaminolevulinate hydrochloride
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … Threonate ... L-threonate ... L-threonic acid …
Matched Name: … L-threonic acid …
Matched Salts name: … Magnesium L-threonate
Dipivefrin is a prodrug of adrenaline, which is used to treat glaucoma. It is available as ophthalmic solution (eye drops).
Approved
Matched Salts name: … Dipivefrin hydrochloride
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … Dipivefrin Hydrochloride ... Propine ... PROPINE
Investigational
Matched Synonyms: … 2-fluoro-5-hydroxy-l-phenylalanine F-18 ... L-phenylalanine, 2-fluoro-5-hydroxy-F-18 ... 6-(18f) fluoro-l-m-tyrosine
Matched Name: … 6-[18F]-Fluoro-L-m-tyrosine
Investigational
Matched Synonyms: … 11c-methionine ... Methionine (11c) ... L-(s-methyl-11c)methionine
Matched Name: … Methionine C-11 …
Matched Categories: … methionine (11C) …
Dapiclermin is a recombinant ciliary neurotrophic factor.
Investigational
Matched Synonyms: … 2-185-ciliary neurotrophic factor (17 -alanine,63-arginine) (human isoform axokine) ... 2-185-(17-alanine,63-agrinine)ciliary neurotrophic factor-(2,185)-peptide (human isoform axokine) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Angiotensin II is under investigation for the treatment of Sepsis, Septic Shock, Diabetes Mellitus, and Acute Renal Failure. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy. As of December 21, 2017 the FDA approved La Jolla Pharmaceutical's...
Approved
Investigational
Matched Synonyms: … 5-isoleucine-angiotensin II ... isoleucine5-angiotensin II …
Matched Description: … Angiotensin II is under investigation for the treatment of Sepsis, Septic Shock, Diabetes Mellitus, and ... , Renin Angiotensin System, and Idiopathic Membranous Nephropathy. ... and death within hours, no matter young or o ld. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Valine is a branched-chain essential amino acid that has stimulant activity. It promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway.
Approved
Nutraceutical
Matched Synonyms: … Valine ... L-valin ... (S)-Valine
Matched Name: … Valine
Matched Description: … It promotes muscle growth and tissue repair. ... Valine is a branched-chain essential amino acid that has stimulant activity. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … O-sulfo-L-serine ... Serine O-sulfate ... O-sulfonato-L-serine
Matched Name: … L-serine O-sulfate …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients who have undergone prior systemic therapies with limited success. Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases and improve survival. On April 23 2021, the Food and Drug Administration granted accelerated...
Approved
Investigational
Matched Synonyms: … immunoglobulin G1 antibody directed against human CD19 conjugated to SG3199 through A protease cleavable valine-alanine
Matched Description: … and improve survival. ... Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients ... [A234439] Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Investigational
Matched Synonyms: … Acetyl-l-leucine ... N-acetyl leucine ... N-Acetyl-Leucine
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … L-valine, l-valyl-, 2-((2-amino-1,6-dihydro-6-oxo-9h-purin-9-yl)methoxy)-3-hydroxypropyl ester …
Matched Name: … Valine-valine-ganciclovir …
Experimental
Matched Synonyms: … Methionine Sulfoxide …
Matched Name: … L-methionine (R)-S-oxide …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic. It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges , eyes , and inner ear . Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins, but worse activity against methicillin-susceptible S.aureus. Ceftriaxone...
Approved
Matched Description: … meninges[A215582], eyes[A215647], and inner ear[A215627]. ... [A215582] It has a very long half-life compared to other cephalosporins and is high penetrable into the ... Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins …
Matched Products: … Ceftriaxone and Dextrose …
Domvanalimab is under investigation in clinical trial NCT05502237 (Zimberelimab and Domvanalimab in Combination With Chemotherapy Versus Pembrolizumab With Chemotherapy in Patients With Untreated Metastatic Non-small Cell Lung Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g1 (236-alanine,237-alanine,de-c-terminal-lysine), anti-(human receptor tigit)(human-mus …
Matched Description: … Domvanalimab is under investigation in clinical trial NCT05502237 (Zimberelimab and Domvanalimab in Combination …
Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed in yeast. It is a glycoprotein that is 127 residues. Substitution of Leu23 leads to a difference from native protein.
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … Leukine
Investigational
Matched Synonyms: … Acetylcysteine lysine ... Lysine acetylcysteinate ... N-acetylcysteinate lysine
Matched Categories: … Amino Acids, Peptides, and Proteins …
A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin.
Experimental
Matched Synonyms: … D-Tyrosin ... (R)-3-(p-Hydroxyphenyl)alanine
Matched Name: … D-Tyrosine
Matched Description: … It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin. ... In animals it is synthesized from PHENYLALANINE. …
Experimental
Matched Synonyms: … O3-acetyl-L-serine ... L-Serine, acetate (ester) …
Matched Name: … O-acetyl-L-serine
Investigational
Matched Synonyms: … Glycine, L-tryptophyl-L-serylglycyl-L-tryptophyl-L-seryl-L-seryl-L-cysteinyl-L-seryl-L-arginyl-L-seryl-L-cysteinyl ... H-L-tryphophanyl-L-seryl-glycyl-L-tryptophanyl-L-seryl-L-seryl-L-cysteinyl-L-seryl-L-arginyl-L-seryl-L-cysteinyl-glycyl-OH …
Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Approved
Matched Description: … It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus …
Matched Categories: … cefuroxime and metronidazole …
Matched Products: … Cefuroxime and Dextrose …
Experimental
Matched Synonyms: … L-N2-(2-Carboxyethyl)arginine ... N2-(2-carboxyethyl)arginine ... N2-(2-Carboxyethyl)-L-arginine
Matched Name: … N(2)-(2-carboxyethyl)-L-arginine
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 401 - 425 of 1131 in total