Displaying drugs 401 - 425 of 8039 in total
N-Acetylglucosamine
The N-acetyl derivative of glucosamine.
Approved
Investigational
Nutraceutical
Matched Description: … The N-acetyl derivative of glucosamine. …
Insulin human
Human Insulin, also known as Regular Insulin, is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Human insulin is produced by recombinant DNA technology and is identical to endogenously produced insulin. Typically prescribed for the management of diabetes mellitus,...
Approved
Investigational
Matched Description: … , with a goal of avoiding any periods of hypoglycemia. ... of insulin in a short period of time to mimic the release of endogenous insulin from the pancreas after ... Insulin is also used in the treatment of Type 2 Diabetes (T2D), another form of diabetes mellitus that …
Pirfenidone
Pirfenidone is a synthetic pyridone drug. It is an antifibrotic agent with anti-inflammatory and antioxidant properties that is used to treat idiopathic pulmonary fibrosis (IPF), which is a chronic, progressive form of interstitial pneumonia. While its mechanism of action is not yet fully understood, pirfenidone is proposed to primarily regulate...
Approved
Investigational
Matched Description: … is used to treat idiopathic pulmonary fibrosis (IPF),[L26801] which is a chronic, progressive form of ... [A251365] The FDA first approved pirfenidone alongside [nintedanib] as one of the first drugs to treat ... [A251370] While its mechanism of action is not yet fully understood, pirfenidone is proposed to primarily …
Chlorcyclizine
Chlorcyclizine is a first generation phenylpiperazine class antihistamine used to treat urticaria, rhinitis, pruritus, and other allergy symptoms. Chlorcyclizine also has some local anesthetic, anticholinergic, and antiserotonergic properties, and can be used as an antiemetic.
Approved
Tedizolid
Drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and penicillin-resistant Streptococcus penumoniae, represent a massive public health threat.[A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the previously approved linezolid and is generally effective against multidrug-resistant Gram-positive bacteria. Tedizolid is indicated for the...
Approved
Investigational
Matched Description: … [A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the ... Tedizolid is indicated for the treatment of acute bacterial skin and skin structure infections (ABSSSI …
Vibegron
Vibegron is a potent, selective beta-3 adrenergic receptor (β3) agonist that relaxes the detrusor smooth muscle of the bladder, thereby increasing bladder capacity. Vibegron was first approved in Japan in September 2018 for the treatment of overactive bladder, a condition associated with distressing symptoms of urge urinary incontinence, urgency, and...
Approved
Investigational
Matched Description: … urinary frequency, and reduced quality of life of patients. ... a potent, selective beta-3 adrenergic receptor (β3) agonist that relaxes the detrusor smooth muscle of ... [L28305] Vibegron was first approved in Japan in September 2018 for the treatment of overactive bladder …
Simvastatin
Simvastatin, also known as the brand name product Zocor, is a lipid-lowering drug derived synthetically from a fermentation product of Aspergillus terreus. It belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid levels by inhibiting the endogenous production...
Approved
Matched Description: … studies to significantly reduce the risk of development of CVD and all-cause mortality. ... It belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease ... and for people with a moderate to high risk of development of CVD, such as those with Type 2 Diabetes …
Riociguat
Riociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for the treatment of patients with inoperable CTEPH (chronic thromboembolic pulmonary hypertension), or persistent/recurrent PH (pulmonary hypertension)...
Approved
Matched Description: … Treatment with riociguat costs USD $7,500 for 30 days of treatment. ... patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for the treatment of …
Malathion
Malathion is a parasympathomimetic organophosphate compound that is used as an insecticide for the treatment of head lice. Malathion is an irreversible cholinesterase inhibitor and has low human toxicity.
Approved
Investigational
Matched Description: … is a parasympathomimetic organophosphate compound that is used as an insecticide for the treatment of …
Cilostazol
Cilostazol is a quinolinone derivative and antiplatelet agent with vasodilating properties that has been used in the symptomatic treatment of intermittent claudication in patients with peripheral ischaemia. It is marketed under the brand name Pletal by Otsuka Pharmaceutical Co.. Cilostazol works by inhibiting both primary and secondary aggregation and reducing...
Approved
Investigational
Matched Description: … and antiplatelet agent with vasodilating properties that has been used in the symptomatic treatment of …
Omega-3 fatty acids
Omega-3 fatty acids are polyunsaturated fatty acids (PUFAs) with a double bond at the third carbon atom from the end of the carbon chain. The three types of omega-3 fatty acids involved in human physiology are α-linolenic acid (ALA) (found in plant oils), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA)...
Approved
Nutraceutical
Matched Description: … acids are polyunsaturated fatty acids (PUFAs) with a double bond at the third carbon atom from the end of ... The three types of omega-3 fatty acids involved in human physiology are α-linolenic acid (ALA) (found ... in fish oil that originally come from microalgae that is further consumed by phytoplankton, a source of …
Lenacapavir
HIV/AIDS remains an area of concern despite the introduction of numerous successful therapies, mainly due to the emergence of multidrug resistance and patient difficulty in adhering to treatment regimens.[A244170, A244175] Lenacapavir is a first-in-class capsid inhibitor that demonstrates picomolar HIV-1 inhibition as a monotherapy in vitro, little to no cross-resistance...
Approved
Investigational
Matched Description: … HIV/AIDS remains an area of concern despite the introduction of numerous successful therapies, mainly ... due to the emergence of multidrug resistance and patient difficulty in adhering to treatment regimens …
Anacaulase
Anacaulase (anacaulase-bcdb) is a mixture of proteolytic enzymes extracted from the stems of pineapple plants (Ananas comosus [L.] Merr.). It is mostly composed (80-95% w/w) of proteins such as stem bromelain, ananain, jacalin-like lectin, bromelain inhibitors, and phytocystatin inhibitor, as well as saccharides, as both free monosaccharides and the N-linked...
Approved
Investigational
Matched Description: … Anacaulase (anacaulase-bcdb) is a mixture of proteolytic enzymes extracted from the stems of pineapple ... It is mostly composed (80-95% w/w) of proteins such as stem bromelain, ananain, jacalin-like lectin, ... phytocystatin inhibitor, as well as saccharides, as both free monosaccharides and the N-linked glycan of …
Entacapone
Entacapone is a selective, reversible catechol-O-methyl transferase (COMT) inhibitor for the treatment of Parkinson's disease. It is a member of the class of nitrocatechols. When administered concomittantly with levodopa and a decarboxylase inhibitor (e.g., carbidopa), increased and more sustained plasma levodopa concentrations are reached as compared to the administration of...
Approved
Investigational
Matched Description: … It is a member of the class of nitrocatechols. ... Entacapone is a selective, reversible catechol-O-methyl transferase (COMT) inhibitor for the treatment of ... increased and more sustained plasma levodopa concentrations are reached as compared to the administration of …
alpha-Tocopherol acetate
Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the...
Approved
Matched Description: … alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the alpha-tocopherol ... Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet ... sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of …
Cannabidiol
Cannabidiol, or CBD, is one of at least 85 active cannabinoids identified within the Cannabis plant. It is a major phytocannabinoid, accounting for up to 40% of the Cannabis plant's extract, that binds to a wide variety of physiological targets of the endocannabinoid system within the body. Although the exact...
Approved
Investigational
Matched Description: … to a wide variety of physiological targets of the endocannabinoid system within the body. ... , a class of compounds that act upon endogenous cannabinoid receptors of the body [A32584]. ... (cannabidiol oral solution) for the treatment of two rare forms of epilepsy - Lennox-Gastaut syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Somapacitan
Somapacitan, also known as NNC0195-0092, is a growth hormone analog indicated to treat adults with growth hormone deficiency.[A219126,L15661] This human growth hormone analog differs by the creation of an albumin binding site, and prolonging the effect so that it requires weekly dosing rather than daily. Somapacitan was granted FDA approval...
Approved
Investigational
Matched Description: … [A219126,L15661] This human growth hormone analog differs by the creation of an albumin binding site, …
Amiodarone
Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings. Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpatient setting for atrial fibrillation. Because of its ability to cause serious toxicity and possibly death, amiodarone...
Approved
Investigational
Matched Description: … Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings. ... Because of its ability to cause serious toxicity and possibly death, amiodarone use should be reserved …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Nicorandil
Nicorandil is an orally efficacious vasodilatory drug and antianginal agent marketed in the UK, Australia, most of Europe, India, Philippines, Japan, South Korea, and Taiwan. It is not an approved drug by FDA. It is a niacinamide derivative that induces vasodilation of arterioles and large coronary arteries by activating potassium...
Approved
Investigational
Matched Description: … is an orally efficacious vasodilatory drug and antianginal agent marketed in the UK, Australia, most of ... It is a niacinamide derivative that induces vasodilation of arterioles and large coronary arteries by ... hyperpolarization via increased transmembrane potassium conductance and increased intracellular concentration of …
Bemiparin
Bemiparin is an antithrombotic and belongs to the group of drugs known as the low molecular weight heparins (LMWH). Like semuloparin, bemiparin is classified as an ultra-LMH because of its low mean molecular mass of 3600 daltons, which is a unique property of this class . These heparins have lower...
Approved
Investigational
Matched Description: … Like semuloparin, bemiparin is classified as an ultra-LMH because of its low mean molecular mass of 3600 ... Interestingly, current research is underway for the potential benefit of bemiparin in the treatment of ... daltons, which is a unique property of this class [A7866]. …
Synthetic Conjugated Estrogens, A
Synthetic conjugated estrogens A are composed of a blend of the following nine synthetic estrogenic substances: estrone sulfate, sodium equilin sulfate, sodium 17α-dihydroequilin sulfate, sodium 17α-estradiol sulfate, sodium 17β dihydroequilin sulfate, sodium 17α-dihydroequilenin sulfate, sodium 17β-dihydroequilenin sulfate, sodium equilenin sulfate, and sodium 17β-estradiol sulfate. This blend of nine estrogen derivatives...
Approved
Matched Description: … of estradiol daily, depending on the phase of the menstrual cycle. ... Synthetic conjugated estrogens A are composed of a blend of the following nine synthetic estrogenic substances ... This blend of nine estrogen derivatives are plant-derived forms of endogenous estrogens and contain many …
Synthetic Conjugated Estrogens, B
Synthetic conjugated estrogens, B tablets contain a blend of ten synthetic estrogenic substances. The estrogenic substances are: sodium estrone sulfate, sodium equilin sulfate, sodium 17α-dihydroequilin sulfate, sodium 17α-estradiol sulfate, sodium 17β dihydroequilin sulfate, sodium 17α-dihydroequilenin sulfate, sodium 17β-dihydroequilenin sulfate, sodium equilenin sulfate, sodium 17β-estradiol sulfate, and sodium Δ8,9-dehydroestrone sulfate. This...
Approved
Matched Description: … of estradiol daily, depending on the phase of the menstrual cycle. ... This blend of ten estrogen derivatives are plant-derived forms of endogenous estrogens and contain many ... There is currently no generic form of CEEs available as a detailed analytical characterization of the …
N-alkyl ethylbenzyl dimethyl ammonium (C12-C14)
N-alkyl ethylbenzyl dimethyl ammonium (c12-c14) is a quaternary ammonium compound with surfactant properties. It is found in sanitizing solutions or soaps as an active ingredient due to its antimicrobial properties.
Employed in a great variety of cleaning agents and sanitizing agents, it possesses relatively broad gram-positive and gram-negative antibacterial activities...
Approved
Matched Description: … action of quaternary ammonium compounds like n-alkyl C12-C14 dimethyl ethylbenzyl ammonium chloride ... activities and relatively little chance for systemic absorption and exposure, although the formal mechanism of ... Employed in a great variety of cleaning agents and sanitizing agents, it possesses relatively broad gram-positive …
Benserazide
When levodopa is used by itself as a therapy for treating Parkinson's disease, its ubiquitous metabolism into dopamine is responsible for a resultant increase in the levels of circulating dopamine in the blood and to various extracerebral tissues. This can result in a number of side effects like nausea, vomiting,...
Approved
Investigational
Matched Description: … disease, its ubiquitous metabolism into dopamine is responsible for a resultant increase in the levels of ... This can result in a number of side effects like nausea, vomiting, or even cardiac arrhythmias that may ... crossing the blood-brain barrier itself but acts to prevent the formation of dopamine from levadopa …
Displaying drugs 401 - 425 of 8039 in total