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Displaying drugs 4226 - 4250 of 5627 in total

Doranidazole

Investigational
Matched Synonyms: … (2rs,3sr)-3-((2-nitroimidazol-1-yl)methoxy)butane-1,2,4-triol ... 1,2,4-butanetriol, 3-((2-nitro-1h-imidazol-1-yl)methoxy)-, (2r,3s)-rel- …
Matched Iupac: … (2R,3S)-3-[(2-nitro-1H-imidazol-1-yl)methoxy]butane-1,2,4-triol …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

1-(3-fluoro-4-(7-(5-methyl-1H-imidazol-2-yl)-1-oxo-2,3-dihydro-1H-isoindo-1-4-yl)-phenyl)-3-(3-trifluoromethyl-phenyl)-urea

Investigational
Matched Synonyms: … Urea, n-(4-(2,3-dihydro-7-(5-methyl-1h-imidazol-2-yl)-1-oxo-1h-isoindol-4-yl)-3-fluorophenyl)-n'-(3-( …
Matched Name: … 1-(3-fluoro-4-(7-(5-methyl-1H-imidazol-2-yl)-1-oxo-2,3-dihydro-1H-isoindo-1-4-yl)-phenyl)-3-(3-trifluoromethyl-phenyl …
Matched Iupac: … 3-{3-fluoro-4-[7-(4-methyl-1H-imidazol-2-yl)-1-oxo-2,3-dihydro-1H-isoindol-4-yl]phenyl}-1-[3-(trifluoromethyl …

Sildenafil

In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614]. The result of doing so allows cGMP present in both the penis and pulmonary vasculature to...
Approved
Investigational
Matched Synonyms: … 1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl) …
Matched Iupac: … 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1H,4H,7H-pyrazolo[4,3-d]pyrimidin …
Matched Description: … /or fatal hypotensive crises [A175579, A175582, A175654]. ... it to grow in size and become erect and rigid [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614 ... The result of doing so allows cGMP present in both the penis and pulmonary vasculature to elicit smooth …
Matched Mixtures name: … DAPOKSEL 30 MG/50 MG FILM TABLET ,3 FILM TABLET ... DAPOXIL 30/50 MG FILM KAPLI TABLET, 3 FILM KAPLI TABLET ... DAPOKSEL 30 MG/50 MG FILM TABLET ,6 FILM TABLET …
Matched Products: … SILDENAFIL BETA 20MG ... SILDENAFIL BETA PAH 20MG …

Masitinib

Masitinib is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in dogs. It has been available in Europe since 2009, under the brand name Masivet. In the USA it is distributed under the name Kinavet and has been available for veterinaries since 2011.
Investigational
Vet approved
Matched Synonyms: … 4-((4-METHYLPIPERAZIN-1-YL)METHYL)-N-(4-METHYL-3-((4-PYRIDIN-3-YL-1,3-THIAZOL-2-YL)AMINO)PHENYL)BENZAMIDE …
Matched Iupac: … N-(4-methyl-3-{[4-(pyridin-3-yl)-1,3-thiazol-2-yl]amino}phenyl)-4-[(4-methylpiperazin-1-yl)methyl]benzamide …
Matched Description: … In the USA it is distributed under the name Kinavet and has been available for veterinaries since 2011 …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Antineoplastic and Immunomodulating Agents ... Protein Kinase Inhibitors …

KX-2361

Investigational
Matched Synonyms: … N-(3-fluorobenzyl)-2-(5-(4-morpholinophenyl) pyridin-2-yl) acetamide ... 2-pyridineacetamide, n-((3-fluorophenyl)methyl)-5-(4-(4-morpholinyl)phenyl)- …
Matched Iupac: … N-[(3-fluorophenyl)methyl]-2-{5-[4-(morpholin-4-yl)phenyl]pyridin-2-yl}acetamide …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Acetates ... Protein Kinase Inhibitors …

Hepatitis B Vaccine (Recombinant)

Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada. The hepatitis B virus induces a severe form of viral hepatitis. Other causative agents are hepatitis...
Approved
Withdrawn
Matched Synonyms: … Hepatitis B virus hbsag surface protein antigen …
Matched Description: … It is estimated that the reservoir of persistent hepatitis B surface antigen carriers amounts to 350 ... Other causative agents are hepatitis A virus, and the non-A, non-B hepatitis viruses. ... epidemiology vary widely among geographical areas and population subgroups. …
Matched Salts name: … Hepatitis B virus subtype ADW HBSAG surface protein antigen ... Hepatitis B virus subtype ADW2 HBSAG surface protein antigen …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Bacterial and viral vaccines, combined ... haemophilus influenzae B and hepatitis B ... Proteins ... Viral Proteins …
Matched Products: … ENGERIX-B ERİŞKİN 20 MCG/ 1ML ENJEKSİYON İÇİN SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTOR, 3 DOZ …

Adenylate-3'-phosphate-[[2'-deoxy-uridine-5'-phosphate]-3'-phosphate]

Experimental
Matched Name: … Adenylate-3'-phosphate-[[2'-deoxy-uridine-5'-phosphate]-3'-phosphate] …
Matched Iupac: … ]-4-hydroxyoxolan-3-yl]oxy}phosphonic acid ... {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-[({[({[(2R,3S,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin ... -1-yl)-2-[(phosphonooxy)methyl]oxolan-3-yl]oxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl …

3-AMINO-3-BENZYL-[4.3.0]BICYCLO-1,6-DIAZANONAN-2-ONE

Experimental
Matched Name: … 3-AMINO-3-BENZYL-[4.3.0]BICYCLO-1,6-DIAZANONAN-2-ONE …

3-fluoro-N-[3-(1H-tetrazol-5-yl)phenyl]benzamide

Experimental
Matched Name: … 3-fluoro-N-[3-(1H-tetrazol-5-yl)phenyl]benzamide …
Matched Iupac: … 3-fluoro-N-[3-(1H-1,2,3,4-tetrazol-5-yl)phenyl]benzamide …

5-imino-4-(3-trifluoromethyl-phenylazo)-5H-pyrazol-3-ylamine

5-imino-4-(3-trifluoromethyl-phenylazo)-5H-pyrazol-3-ylamine is a solid. This compound belongs to the benzene and substituted derivatives. These are aromatic compounds containing at least one benzene ring. This drug targets the protein methionine aminopeptidase.
Experimental
Matched Name: … 5-imino-4-(3-trifluoromethyl-phenylazo)-5H-pyrazol-3-ylamine …
Matched Iupac: … 4-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-4,5-dihydro-3H-pyrazole-3,5-diimine …
Matched Description: … This compound belongs to the benzene and substituted derivatives. ... This drug targets the protein methionine aminopeptidase. ... 5-imino-4-(3-trifluoromethyl-phenylazo)-5H-pyrazol-3-ylamine is a solid. …

RP-L201

Investigational
Matched Synonyms: … Hematopoietic stem cells modified with a lentiviral vector containing the CD18 (integrin beta 2) gene …

Dyclonine

Dyclonine is an oral anaesthetic found in Sucrets, an over the counter throat lozenge. It may also be found in some Cepacol sore throat spray products.
Approved
Matched Synonyms: … 3-piperidino-4'-butoxypropiophenone ... 4'-butoxy-3-piperidinopropiophenone ... 1-(4-Butoxyphenyl)-3-(1-piperidinyl)-1-propanone …
Matched Iupac: … 1-(4-butoxyphenyl)-3-(piperidin-1-yl)propan-1-one …
Matched Mixtures name: … Salicylic Acid ... Benzethonium Chloride and Dyclonine Hydrochloride ... Benzethonium chloride and Dyclonine hydrochloride …
Matched Salts name: … Dyclonine hydrochloride …
Matched Products: … Sucrets Extra Strength Mint Flav.loz 3mg …

Edralbrutinib

Edralbrutinib is an orally available small molecule inhibitor of Bruton's tyrosine kinase.
Investigational
Matched Synonyms: … 4-amino-3-(4-(2,6-difluorophenoxy)phenyl)-1,6-dihydro-1-((3r)-1-(1-oxo-2-butyn-1-yl)-3-pyrrolidinyl)- ... oxo-2-butyn-1-yl)-3-pyrrolidinyl)- ... 7h-pyrrolo(2,3-d)pyridazin-7-one, 4-amino-3-(4-(2,6-difluorophenoxy)phenyl)-1,6-dihydro-1-((3r)-1-(1- …
Matched Iupac: … 4-amino-1-[(3R)-1-(but-2-ynoyl)pyrrolidin-3-yl]-3-[4-(2,6-difluorophenoxy)phenyl]-1H,6H,7H-pyrrolo[2,3 …

N-(CYCLOPROPYLMETHYL)-4-(METHYLOXY)-3-({5-[3-(3-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-YL}AMINO)BENZENESULFONAMIDE

Experimental
Matched Name: … N-(CYCLOPROPYLMETHYL)-4-(METHYLOXY)-3-({5-[3-(3-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-YL}AMINO)BENZENESULFONAMIDE …
Matched Iupac: … N-(cyclopropylmethyl)-4-methoxy-3-({5-[3-(pyridin-3-yl)phenyl]-1,3-oxazol-2-yl}amino)benzene-1-sulfonamide …

ST-101

ST-101 is a small peptide antagonist of C/EBPβ and T-type calcium channel activator. ST101 has been used in trials studying the treatment of Essential Tremor and Alzheimer's Disease.
Investigational
Matched Synonyms: … ST-101 (D-AMINO ACID PEPTIDE) ... C/EBP Beta Antagonist ST101 …
Matched Description: … ST-101 is a small peptide antagonist of C/EBPβ and T-type calcium channel activator. ... ST101 has been used in trials studying the treatment of Essential Tremor and Alzheimer's Disease. …

Nepidermin

Experimental
Matched Synonyms: … Beta-urogastrone …
Matched Mixtures name: … Artemes 3R effect hyaluronic mask ... ARTEMES 3R Effect Hyaluronic Ampoule …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Proteins ... EGF Family of Proteins …
Matched Products: … EASYDEW EX REPAIR CONTROL REPAIR CONTROL EGF 3mL …

P1-(5'-Adenosyl)P5-(5'-(3'azido-3'-Deoxythymidyl))Pentaphosphate

Experimental
Matched Name: … P1-(5'-Adenosyl)P5-(5'-(3'azido-3'-Deoxythymidyl))Pentaphosphate …
Matched Iupac: … }oxy)(oxido)phosphoryl]oxy}(hydroxy)phosphoryl phosphonato)oxy](oxido)phosphoryl}oxy)methyl]-4-azidooxolan ... 1-[(2R,4S,5S)-5-[({[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonato …

(3S)-N-(3-BROMOPHENYL)-1-CYCLOHEXYL-5-OXOPYRROLIDINE-3-CARBOXAMIDE

Experimental
Matched Name: … (3S)-N-(3-BROMOPHENYL)-1-CYCLOHEXYL-5-OXOPYRROLIDINE-3-CARBOXAMIDE …
Matched Iupac: … (3S)-N-(3-bromophenyl)-1-cyclohexyl-5-oxopyrrolidine-3-carboxamide …

Lotilaner

Lotilaner is an ectoparasiticide that is a member of the isoxazoline family of compounds. Lotilaner has largely been used for veterinary uses as an antiparasitic agent to treat flea and tick infestations in animals.[A260746, L47556] Lotilaner consists of two enantiomers: the S-enantiomer is active in vivo, while the R-enantiomer is...
Approved
Vet approved
Matched Synonyms: … )-4,5-dihydro-1,2-oxazol-3-yl)thiophene-2-carboxamide ... )-3-methyl-n-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)- ... 2-thiophenecarboxamide, 5-((5s)-4,5-dihydro-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-3-isoxazolyl …
Matched Iupac: … 2-({3-methyl-5-[(5S)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]thiophen …
Matched Description: … L47546] Lotilaner has largely been used for veterinary uses as an antiparasitic agent to treat flea and ... 2023, lotilaner was approved by the FDA for the treatment of Demodex blepharitis, making it the first and …
Matched Categories: … Scabicides, Insecticides and Repellents …

(1S)-2-oxo-1-phenyl-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate

Experimental
Matched Name: … (1S)-2-oxo-1-phenyl-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate …
Matched Iupac: … (S)-phenyl[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)carbamoyl]methyl acetate …

Diosmin

Chronic venous insufficiency is a common condition the western population. Compression and pharmacotherapy are frequently used to manage chronic venous insufficiency, improving circulation and symptoms of venous disease. Diosmin is a bioflavonoid isolated from various plants or synthesized from hesperidin. It is used for the improvement of capillary fragility or...
Approved
Investigational
Matched Synonyms: … 3',5,7-trihydroxy-4'-methoxyflavone-7-rutinoside ... 3',5,7-trihydroxy-4'-methoxyflavone 7-rhamnoglucoside …
Matched Iupac: … 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5 …
Matched Description: … circulation and symptoms of venous disease. ... Compression and pharmacotherapy are frequently used to manage chronic venous insufficiency, improving ... improvement of capillary fragility or venous insufficiency, including chronic venous insufficiency (CVI) and …
Matched Mixtures name: … VENAFIX (Diosmin and Hesperidin Tablet) ... DIOKERN 450 MG/50 MG FILM KAPLI TABLET,30 ADET ... VARIDOS 450 MG/50 MG FILM KAPLI TABLET, 30 ADET …
Matched Products: … VENDIOS 600 MG TABLET, 30 ADET …

Normethadone

Normethadone is used as an opioid antitussive in combination with DB11610. It is marketed in Canada by Valeant under the tradename Cophylac.
Approved
Illicit
Matched Synonyms: … 6-dimethylamino-4,4-diphenyl-3-hexanone …
Matched Iupac: … 6-(dimethylamino)-4,4-diphenylhexan-3-one …
Matched Salts name: … Normethadone hydrochloride …
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives …

Namodenoson

Namodenoson has been used in trials studying the treatment of Chronic Hepatitis C and Hepatocellular Carcinoma.
Investigational
Matched Synonyms: … 2-Chloro-N(6)-(3-iodobenzyl)adenosine-5'-N-methyluronamide …
Matched Iupac: … (2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl]amino}-9H-purin-9-yl)-3,4-dihydroxy-N-methyloxolane …
Matched Description: … Namodenoson has been used in trials studying the treatment of Chronic Hepatitis C and Hepatocellular …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Foslevodopa

Foslevodopa is under investigation in clinical trial NCT04750226 (Study to Assess Adverse Events and Change in Disease Activity of 24-hour Continuous Subcutaneous Infusion of ABBV-951 in Adult Participants With Advanced Parkinson's Disease).
Approved
Investigational
Matched Synonyms: … 3-hydroxy-O-phosphono-L-tyrosine …
Matched Iupac: … (2S)-2-amino-3-[3-hydroxy-4-(phosphonooxy)phenyl]propanoic acid …
Matched Description: … Foslevodopa is under investigation in clinical trial NCT04750226 (Study to Assess Adverse Events and …
Matched Categories: … Dopa and Dopa Derivatives ... foslevodopa and decarboxylase inhibitor …

ABT-737

An inhibitor of members of the Bcl‑2 family of apoptosis regulators.
Investigational
Matched Synonyms: … -1-((phenylthio)methyl)propyl)amino)-3-nitrophenyl)sulfonyl)- ... Benzamide, 4-(4-((4'-chloro(1,1'-biphenyl)-2-yl)methyl)-1-piperazinyl)-n-((4-(((1r)-3-(dimethylamino) …
Matched Iupac: … biphenyl]-2-yl}methyl)piperazin-1-yl]-N-(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)butan-2-yl]amino}-3- …
Matched Categories: … Proto-Oncogene Proteins c-bcl-2 …
Displaying drugs 4226 - 4250 of 5627 in total