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Displaying drugs 4426 - 4450 of 5282 in total
Experimental
Matched Name: … 5-[2-(4-hydroxyphenyl)ethyl]benzene-1,3-diol …
Matched Iupac: … 5-[2-(4-hydroxyphenyl)ethyl]benzene-1,3-diol …
Experimental
Matched Name: … 3-(4-fluorophenyl)-5-phenyl-4H-1,2,4-triazole …
Matched Iupac: … 3-(4-fluorophenyl)-5-phenyl-4H-1,2,4-triazole …
Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old. Due to concerns about the risk of hepatotoxicity, nimesulide has...
Approved
Investigational
Withdrawn
Matched Iupac: … N-(4-nitro-2-phenoxyphenyl)methanesulfonamide …
Matched Description: … Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and ... primary dysmenorrhoea in adolescents and adults above 12 years old. ... Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates …
Matched Products: … NIMELID %1 JEL, 20 G …
An anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
Approved
Matched Synonyms: … N-Acetyl-4-aminobenzenesulfonamide ... N(1)-Acetyl-4-aminophenylsulfonamide …
Matched Iupac: … N-(4-aminobenzenesulfonyl)acetamide …
Matched Description: … An anti-infective agent that is used topically to treat skin infections and orally for urinary tract …
Matched Mixtures name: … Salicylic Acid 2% /sodium Sulfacetamide Monohydrate 8% ... Salicylic Acid 2% / Sodium Sulfacetamide Monohydrate 8% ... Salicylic Acid 5% / Sodium Sulfacetamide Monohydrate 10% …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Experimental
Matched Name: … 8-(6-BROMO-BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISOPROPYLAMINO-PROPYL)-ADENINE …
Vet approved
Matched Synonyms: … 4-amino-N-(6-ethoxy-3-pyridazinyl)benzenesulfonamide …
Matched Iupac: … 4-amino-N-(6-ethoxypyridazin-3-yl)benzene-1-sulfonamide …
Investigational
Matched Synonyms: … 1-[2-[4-(2-amino-5-chloropyridin-3-yl)phenoxy]pyrimidin-5-yl]-3-[2-methylsulfonyl-5-(trifluoromethyl) …
Matched Salts name: … ONO-7579 Mono-4-Toluenesulfonate …
BMS-741672 is under investigation in clinical trial NCT00699790 (Proof of Confidence Study of CCR2 Antagonist (BMS-741672) in Insulin Resistance).
Investigational
Matched Synonyms: … N-(5-(ISOPROPYL(METHYL)AMINO)-2-(2-OXO-3-((6-(TRIFLUOROMETHYL)QUINAZOLIN-4-YL)AMINO)PYRROLIDIN-1-YL)CYCLOHEXYL …
One of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.
Approved
Investigational
Vet approved
Matched Synonyms: … 4-amino-N-2-pyrimidinylbenzenesulfonamide …
Matched Iupac: … 4-amino-N-(pyrimidin-2-yl)benzene-1-sulfonamide …
Matched Description: … combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and
Matched Mixtures name: … SDMT 480 Water Soluble Powder ... Zuprim 480 Water Soluble Powder ... ST-480 Powder …
Matched Categories: … Sulfonamides and trimethoprim ... sulfadiazine and tetroxoprim ... Genito Urinary System and Sex Hormones ... sulfadiazine and trimethoprim ... Gynecological Antiinfectives and Antiseptics …
Myelodysplastic syndromes (MDS) are a heterogeneous group of hematopoietic neoplasms with variable underlying etiology and presentation, including neutropenia and thrombocytopenia. Further mutations leading to increased proliferation of cancerous cells can eventually lead to secondary acute myeloid leukemia, which has a poor prognosis.[A215082, A215092] Among treatment options, nucleoside analogues such as...
Approved
Investigational
Matched Synonyms: … 4-amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-s-triazin-2(1H)-one …
Matched Iupac: … 4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one …
Matched Description: … approved by the FDA for the treatment of MDS on February 5, 2006. ... presentation, including neutropenia and thrombocytopenia. ... and related downstream therapeutic benefits. …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Antineoplastic and Immunomodulating Agents ... Nucleic Acid Synthesis Inhibitors …
Bedaquiline is a bactericidal antimycobacterial drug belonging to the class of diarylquinoline. The quinolinic central heterocyclic nucleus with alcohol and amine side chains is responsible for bedaquiline-mediated antimycobacterial activity. Although it is closely related to fluoroquinolones, bedaquiline does not affect DNA gyrase; instead, bedaquiline inhibits the c subunit of ATP...
Approved
Matched Synonyms: … 1-(6-Bromo-2-methoxy-quinolin-3-yl)-4-dimethylamino-2-naphthalen-1-yl-1-phenyl-butan-2-ol …
Matched Iupac: … (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol …
Matched Description: … favorable results in multiple pre-clinical and clinical studies. ... The quinolinic central heterocyclic nucleus with alcohol and amine side chains is responsible for bedaquiline-mediated ... [rifampin], is highly effective, the emergence of multidrug-resistant TB (MDR-TB) to [isoniazid] and
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates …
Experimental
Matched Synonyms: … 1-(4-Hydroxyphenyl)-1-hydroxy-2-butylaminoethane …
Matched Iupac: … 4-[2-(butylamino)-1-hydroxyethyl]phenol …
Matched Salts cas: … 5716-20-1 …
Investigational
Matched Synonyms: … )hept-5-yl-4-pyrimidinyl)- ... 2-pyridinamine, 3-(difluoromethoxy)-5-(2-(3,3-difluoro-1-pyrrolidinyl)-6-(1s,4s)-2-oxa-5-azabicyclo(2.2.1 …
Matched Iupac: … ]pyrimidin-4-yl]pyridin-2-amine ... 3-(difluoromethoxy)-5-[2-(3,3-difluoropyrrolidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl …
Investigational
Matched Synonyms: … tetrayl-.kappa.n21,.kappa.n22,.kappa.n23,.kappa.n24)tetrakis(1-(2-butoxyethyl)pyridiniumato))(2-))-, (sp-4- …
Matched Iupac: … butoxyethyl)pyridin-1-ium-2-yl]-21,22,23,24-tetraazapentacyclo[16.2.1.1^{3,6}.1^{8,11}.1^{13,16}]tetracosa-1(20
Ethchlorvynol is a sedative and hypnotic drug. It has been used to treat insomnia, but has been largely superseded and is only offered where an intolerance or allergy to other drugs exists.
Approved
Illicit
Withdrawn
Matched Synonyms: … 1-chloro-3-ethyl-1-penten-4-yn-3-ol ... 1-Chloro-3-ethyl-pent-1-en-4-yn-3-ol …
Matched Iupac: … (1E)-1-chloro-3-ethylpent-1-en-4-yn-3-ol …
Matched Description: … Ethchlorvynol is a sedative and hypnotic drug. ... It has been used to treat insomnia, but has been largely superseded and is only offered where an intolerance …
Matched Categories: … Hypnotics and Sedatives …
Resmetirom is a thyroid hormone receptor-beta (THR-beta) agonist. On March 14, 2024, it was approved by the FDA as the first treatment of liver fibrosis due to noncirrhotic non-alcoholic steatohepatitis (NASH), which is a form of non-alcoholic fatty liver disease (NAFLD). Thyroid hormones directly regulate lipid metabolism in the liver;...
Approved
Investigational
Matched Synonyms: … 1,2,4-Triazine-6-carbonitrile, 2-[3,5-dichloro-4-[[1,6-dihydro-5-(1-methylethyl)-6-oxo-3-pyridazinyl] ... 2-[3,5-Dichloro-4-[[1,6-dihydro-5-(1-methylethyl)-6-oxo-3-pyridazinyl]oxy]phenyl]-2,3,4,5-tetrahydro- …
Matched Iupac: … 2-(3,5-dichloro-4-{[6-oxo-5-(propan-2-yl)-1,6-dihydropyridazin-3-yl]oxy}phenyl)-3,5-dioxo-2,3,4,5-tetrahydro …
Matched Description: … [A263461] Resmetirom works to reduce liver fat by stimulating fatty acid degradation and oxidation. ... On March 14, 2024, it was approved by the FDA as the first treatment of liver fibrosis due to noncirrhotic …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C8 Inhibitors ... Cytochrome P-450 CYP2C8 Substrates ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP2C8 Inhibitors (weak) …
Investigational
Matched Synonyms: … 2-(4-(2,4-dichlorophenethyl)-3,6-dioxo-1-(2-(thiophen-2-yl)ethyl)piperazin-2-yl)-n-(2-(5-methoxy-1h-indol ... 2-piperazineacetamide, 4-(2-(2,4-dichlorophenyl)ethyl)-n-(2-(5-methoxy-1h-indol-3-yl)ethyl)-3,6-dioxo ... 2-(4-(2,4-dichlorophenethyl)-3,6-dioxo-1-(2-(thiophen-2-yl)ethyl)piperazin-2-yl)-n-(2-(5-methoxy-1h-indol …
Matched Iupac: … 2-{4-[2-(2,4-dichlorophenyl)ethyl]-3,6-dioxo-1-[2-(thiophen-2-yl)ethyl]piperazin-2-yl}-N-[2-(5-methoxy …
Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.[L12207,A176173] Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabetes without causing hypoglycemia. It is commonly described as an "insulin sensitizer", leading to a decrease in insulin...
Approved
Matched Description: … Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management ... It is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and ... [A36559] Metformin was first approved in Canada in 1972,[A36552] and received subsequent FDA approval …
Matched Salts cas: … 1115-70-4
Matched Mixtures name: … VILMET 50 MG/1000 MG FILM KAPLI TABLET ,1TABLET, 20 ADET ... AMARYL®M 4 MG/ 1000 MG ... GLIBOMET FİLM KAPLI TABLET, 40 ADET …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and ertugliflozin ... metformin and gemigliptin ... metformin and sulfonylureas ... metformin and linagliptin …
Matched Products: … Glycon
Sotatercept is an activin signalling inhibitor. It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. On March 26, 2024, sotatercept was approved by the FDA for the treatment of pulmonary arterial hypertension...
Approved
Investigational
Matched Synonyms: … (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN ... (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN …
Matched Description: … [L50361] Sotatercept works to resolve the imbalance in activin–growth differentiation factor and BMP ... [L50351] On March 26, 2024, sotatercept was approved by the FDA for the treatment of pulmonary arterial …
Matched Categories: … Amino Acids, Peptides, and Proteins …
A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
Approved
Investigational
Matched Synonyms: … 4,4'- (Isopropylidenedithio)bis(2,6-di-tert-butylphenol) ... Acetone bis(3,5-di-tert-butyl-4-hydroxyphenyl) mercaptole …
Matched Iupac: … 2,6-di-tert-butyl-4-({2-[(3,5-di-tert-butyl-4-hydroxyphenyl)sulfanyl]propan-2-yl}sulfanyl)phenol …
Matched Description: … A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol …
Methylchloroisothiazolinone (MCI) is an isothiazolinone commonly used as a preservative with antibacterial and antifungal properties. It is found within many commercially available cosmetics, lotions, and makeup removers. It is also a known dermatological sensitizer and allergen; some of its side effects include flaky or scaly skin, breakouts, redness or itchiness,...
Approved
Experimental
Matched Synonyms: … 4-Isothiazolin-3-one, 5-chloro-2-methyl- …
Matched Description: … Methylchloroisothiazolinone (MCI) is an isothiazolinone commonly used as a preservative with antibacterial and ... It is found within many commercially available cosmetics, lotions, and makeup removers. ... It is also a known dermatological sensitizer and allergen; some of its side effects include flaky or …
Tomivosertib is under investigation in clinical trial NCT03318562 (A PD Study of Oral eFT508 in Subjects With Advanced TNBC and HCC).
Investigational
Matched Synonyms: … 6'-((6-Amino-4-pyrimidinyl)amino)-8'-methyl-2'H-spiro(cyclohexane-1,3'-imidazo(1,5-a)pyridine)-1',5'- …
Matched Iupac: … 6'-[(6-aminopyrimidin-4-yl)amino]-8'-methyl-2',5'-dihydro-1'H-spiro[cyclohexane-1,3'-imidazo[1,5-a]pyridine …
Matched Description: … investigation in clinical trial NCT03318562 (A PD Study of Oral eFT508 in Subjects With Advanced TNBC and
Tirabrutinib is under investigation in clinical trial NCT02626026 (Safety and Pharmacokinetics of GS-4059 in Healthy Volunteers and Subjects With Rheumatoid Arthritis (RA)).
Investigational
Matched Synonyms: … 6-amino-9-[(3R)-1-but-2-ynoylpyrrolidin-3-yl]-7-(4-phenoxyphenyl)purin-8-one …
Matched Iupac: … 6-amino-9-[(3R)-1-(but-2-ynoyl)pyrrolidin-3-yl]-7-(4-phenoxyphenyl)-8,9-dihydro-7H-purin-8-one …
Matched Description: … Tirabrutinib is under investigation in clinical trial NCT02626026 (Safety and Pharmacokinetics of GS- ... 4059 in Healthy Volunteers and Subjects With Rheumatoid Arthritis (RA)). …
Suzetrigine is under investigation in clinical trial NCT05558410 (Evaluation of Efficacy and Safety of VX-548 for Acute Pain After an Abdominoplasty).
Investigational
Matched Synonyms: … 4-[[[(2R,3S,4S,5R)-3-(3,4-Difluoro-2-methoxyphenyl)tetrahydro-4,5-dimethyl-5-(trifluoromethyl)-2-furanyl …
Matched Description: … Suzetrigine is under investigation in clinical trial NCT05558410 (Evaluation of Efficacy and Safety of …
Gamma cyclodextrin is under investigation in clinical trial NCT03931057 (The use of ADV6209 for Premedication in Pediatric Anesthesia).
Investigational
Matched Synonyms: … Cyclooctakis-(1->4)-(.alpha.-d-glucopyranosyl) …
Displaying drugs 4426 - 4450 of 5282 in total