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Displaying drugs 426 - 450 of 6574 in total
Benztropine, with the chemical formula 3alpha-diphenylmethoxytropane, is a tropane-based dopamine inhibitor used for the symptomatic treatment of Parkinson's disease. It is a combination molecule between a tropane ring, similar to cocaine, and a diphenyl ether from the dialkylpiperazines determined to be a dopamine uptake inhibitor since 1970. The generation of...
Approved
Matched Synonyms: … 3-alpha-(diphenylmethoxy)tropane ... benzhydryl 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ether …
Matched Iupac: … (1R,3R,5S)-3-(diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane …
Matched Description: … It is a combination molecule between a tropane ring, similar to cocaine, and a diphenyl ether from the ... dialkylpiperazines determined to be a dopamine uptake inhibitor since 1970. ... Benztropine, with the chemical formula 3alpha-diphenylmethoxytropane, is a tropane-based dopamine inhibitor …
Matched Salts cas: … 132-17-2
Matched Products: … TICOLIN 2 MG/2 ML IM/IV ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL,1 ADET ... COGENTIN INJECTION 2 mg/2 ml ... BENZATROPINE PHEBRA SOLUTION FOR INJECTION 2 MG/2 ML …
A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with anemia, short stature, hypogonadism, impaired wound...
Approved
Investigational
Matched Description: … polymorphism of the common polymorphism in zinc transporter _SLC30A8/ZnT8_ may increase susceptibility to type 2 ... A metallic element of atomic number 30 and atomic weight 65.38. ... It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an …
Matched Mixtures name: … Acti-cal/mag 2:1 + Zinc and D Caplet ... Chelated Cal-mag(2:1)with Zn Vit.c and D ... ADDAMEL N
Matched Products: … Port A Mins Super Zinc 15 ... Port A Mins Super Zinc 30 …
Tigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil. It was developed in response to the growing prevalence of antibiotic resistance in bacteria such as Staphylococcus aureus. It was granted fast-track approval by the U.S. Food and Drug Administration (FDA) on June 17, 2005.
Approved
Matched Synonyms: … -3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide ... (4S,4aS,5aR,12aS)-9-(2-(tert-butylamino)acetamido)-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro …
Matched Iupac: … -dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide ... (4S,4aS,5aR,12aS)-9-[2-(tert-butylamino)acetamido]-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11 …
Matched Description: … Tigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil …
Matched Products: … INFÜZYON IÇIN LIYOFILIZE TOZ IÇEREN FLAKON,FLAKON, 1 ADET ... TIGECLIN ® POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE. ... TIGECICLINA 50 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …
Larotrectinib is an orally administered inhibitor of tropomyosin receptor kinase (Trk), a receptor tyrosine kinase activated by neurotrophins which is mutated in a variety of cancer cell types and plays an important role in tumor cell growth and survival. Upon administration, larotrectinib binds to Trk, thereby preventing neurotrophin-Trk interaction and...
Approved
Investigational
Matched Iupac: … (3S)-N-{5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl}-3-hydroxypyrrolidine ... -1-carboxamide …
Matched Description: … [L49821] Larotrectinib was granted accelerated approval by the FDA in November 2018 for the treatment ... Larotrectinib is an orally administered inhibitor of tropomyosin receptor kinase (Trk), a receptor tyrosine ... kinase activated by neurotrophins which is mutated in a variety of cancer cell types and plays an important …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Bordetella pertussis fimbriae 2/3 antigen is a vaccine for the prophylaxis of the disease caused by Bordetella pertussis which is a a Gram-negative coccobacillus that expresses two serologically distinct fimbriae (Fim2 and Fim3).
Approved
Investigational
Matched Synonyms: … Bordetella pertussis fimbriae 2/3 vaccine, inactivated
Matched Name: … Bordetella pertussis fimbriae 2/3 antigen
Matched Description: … Bordetella pertussis fimbriae 2/3 antigen is a vaccine for the prophylaxis of the disease caused by Bordetella ... pertussis which is a a Gram-negative coccobacillus that expresses two serologically distinct fimbriae …
Matched Mixtures name: … ANTIGEN, and BORDETELLA PERTUSSIS FIMBRIAE 2/3 ANTIGEN ... CLOSTRIDIUM TETANI TOXOID ANTIGEN (FORMALDEHYDE INACTIVATED), CORYNEBACTERIUM DIPHTHERIAE TOXOID ANTIGEN ... (FORMALDEHYDE INACTIVATED), BORDETELLA PERTUSSIS TOXOID ANTIGEN (GLUTARALDEHYDE INACTIVATED), BORDETELLA …
Matched Categories: … Inactivated Bordetella Pertussis Vaccine …
Potassium is an essential nutrient, like Calcium and Magnesium. It was identified as a shortfall nutrient by the 2015-2020 Advisory Committee of Dietary Guidelines for Americans. Many conditions and diseases interfere with normal body potassium balance, and underconsumption of potassium is one example. Hypokalemia (low potassium) or hyperkalemia (high potassium)...
Approved
Experimental
Matched Description: … It was identified as a shortfall nutrient by the 2015-2020 Advisory Committee of Dietary Guidelines for ... Potassium is often a key ingredient for intravenous fluids, given to patients in clinical settings for …
Matched Mixtures name: … BION 3 FILM COATED TABLET ... Spectrum 2 Cap ... Calcium and Magnesium 1:1 Plus Tablets …
Matched Products: … Port A Mins Super Potassium 99 …
Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.[A233300,L13362] Both bisacodyl and picosulfate are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).[A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956 but has been used as a laxative since 1952.
Approved
Matched Synonyms: … Phenol, 4,4'-(2-pyridinylmethylene)bis-, diacetate (ester) …
Matched Iupac: … 4-{[4-(acetyloxy)phenyl](pyridin-2-yl)methyl}phenyl acetate …
Matched Description: … bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2- ... Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional ... A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as a
Matched Mixtures name: … GaviLyte-H and Bisacodyl ... BEKUNIS 3 MG/5 MG KAPLI TABLET, 30 ADET …
Matched Products: … Lax-A Go ... Feen-A-mint - Ect 5mg …
Iptacopan is a small-molecule factor B inhibitor previously investigated as a potential treatment for the rare blood disease paroxysmal nocturnal hemoglobinuria (PNH) by inhibiting the complement factor B. Factor B is a positive regulator of the alternative complement pathway, where it activates C3 convertase and subsequently C5 convertase. This is...
Approved
Investigational
Matched Synonyms: … 4-((2S,4S)-4-ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl) benzoic acid ... BENZOIC ACID, 4-((2S,4S)-4-ETHOXY-1-((5-METHOXY-7-METHYL-1H-INDOL-4-YL)METHYL)-2-PIPERIDINYL)- …
Matched Iupac: … 4-[(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl]benzoic acid …
Matched Description: … Iptacopan is a small-molecule factor B inhibitor previously investigated as a potential treatment for ... [A262566] Factor B is a positive regulator of the alternative complement pathway, where it activates ... progeny erythrocytes will lack the glycosyl phosphatidylinositol–anchored proteins that normally anchor 2
Matched Salts cas: … 2447007-60-3
Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration . It was initially approved by the FDA in 1991 . It is primarily used for the treatment of respiratory, enteric and genitourinary infections and may be used instead of other macrolides for...
Approved
Matched Iupac: … (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl ... -heptamethyl-1-oxa-6-azacyclopentadecan-15-one ... ]oxy}-2-ethyl-3,4,10-trihydroxy-13-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,6,8,10,12,14 …
Matched Description: … Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue ... , and contains a 15-membered ring, with a methyl-substituted nitrogen instead of a carbonyl group at ... -19 with a combination of azithromycin and the anti-malaria drug [hydroxychloroquine]. …
Matched Products: … ZITHROMAX TR-SAFT K B 25KG ... ZITROTEK FILM KAPLI TABLET, 2 ADET ... AZİTROTEK 500 MG FİLM TABLET, 2 TABLET …
Betamethasone phosphate is a prodrug that is rapidly hydrolyzed, providing rapidly accessible betamethasone to agonize glucocorticoid receptors. Betamethasone provides greater anti-inflammatory activity than prednisolone with less sodium and water retention. Betamethasone sodium phosphate was granted FDA approval on 3 March 1965.
Approved
Vet approved
Matched Iupac: … ,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethoxy}phosphonic acid ... {2-[(1R,2S,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-1,10-dihydroxy-2,9a,11a-trimethyl-7-oxo-1H,2H,3H,3aH,3bH …
Matched Description: … [L11994] Betamethasone sodium phosphate was granted FDA approval on 3 March 1965.[L11994] ... Betamethasone phosphate is a prodrug that is rapidly hydrolyzed, providing rapidly accessible [betamethasone …
Zinc gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc cation (2+). Zinc gluconate is a generally recognized as safe (GRAS) substance by FDA . It is available as a trace mineral supplement and over the counter as a lozenge form for...
Approved
Vet approved
Matched Iupac: … zinc(2+) ion bis((2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate) …
Matched Description: … cation (2+). ... It is available as a trace mineral supplement and over the counter as a lozenge form for a reduced duration ... Zinc gluconate is a generally recognized as safe (GRAS) substance by FDA [L2081]. …
Matched Mixtures name: … Super Daily No 2 ... KORDEL`S EXECUTIVE B TABLET ... Extra 11
Matched Products: … ZINC INJECTABLE A 1mg/ml, solution injectable pour perfusion ... Zink Aguettant 1 mg/ml Konzentrat zur Herstellung einer Infusionslösung …
Famciclovir, marketed as Famvir by Novartis, is a guanine analogue used to treat herpes virus infections. It is most commonly used to treat herpes zoster (shingles). Famciclovir is a prodrug of penciclovir with higher oral bioavailability.
Approved
Investigational
Matched Synonyms: … 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine ... 2-(2-(2-amino-9H-purin-9-yl)ethyl)-1,3-propanediol diacetate ... acetic acid 2-acetoxymethyl-4-(2-amino-purin-9-yl)-butyl ester …
Matched Iupac: … 2-[(acetyloxy)methyl]-4-(2-amino-9H-purin-9-yl)butyl acetate …
Matched Description: … Famciclovir, marketed as Famvir by Novartis, is a guanine analogue used to treat herpes virus infections ... Famciclovir is a prodrug of penciclovir with higher oral bioavailability. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor …
Inositol is a collection of nine different stereoisomers but the name is usually used to describe only the most common type of inositol, myo-inositol. Myo-inositol is the cis-1,2,3,5-trans-4,6-cyclohexanehexol and it is prepared from an aqueous extract of corn kernels by precipitation and hydrolysis of crude phytate. These molecules have structural...
Approved
Investigational
Withdrawn
Matched Description: … It is considered a pseudovitamin as it is a molecule that does not qualify to be an essential vitamin ... Inositol is a collection of nine different stereoisomers but the name is usually used to describe only ... because even though its presence is vital in the body, a deficiency in this molecule does not translate …
Matched Mixtures name: … Hoa 1 ... Vege 1 Daily Tab ... For-2
Matched Categories: … Vitamin B Complex …
Erenumab (AMG-334) (INN; trade name Aimovig) is a human monoclonal antibody designed specifically to bind and antagonize the calcitonin gene-related peptide receptor (CGRPR) as a means to prevent migraines. Aimovig, as released and marketed by Novartis and Amgen, is in fact a novel therapeutic approach as the first and only...
Approved
Investigational
Matched Description: … It is composed of 2 heavy chains, each containing 456 amino acids, and 2 light chains of the lambda subclass ... Erenumab (AMG-334) (INN; trade name Aimovig) is a human monoclonal antibody designed specifically to ... bind and antagonize the calcitonin gene-related peptide receptor (CGRPR) as a means to prevent migraines …
Matched Products: … Pasurta 70mg/ml Solution for Injection in a Prefilled Syringe ... KUZELVA 70 MG ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET …
Butylscopolamine is a peripherally acting antimuscarinic, anticholinergic agent. It is used to treat pain and discomfort caused by abdominal cramps, menstrual cramps, or other spasmodic activity in the digestive system. It is also effective at preventing bladder spasms. It is not a pain medication in the normal sense, since it...
Approved
Investigational
Vet approved
Matched Synonyms: … N-butylscopolammonium ... N-butylscopolammonium ion ... N-butylscopolammonium cation …
Matched Iupac: … (1R,2R,4S,5S,7R)-9-butyl-7-{[(2S)-3-hydroxy-2-phenylpropanoyl]oxy}-9-methyl-3-oxa-9-azatricyclo[3.3.1.0 …
Matched Description: … Butylscopolamine is a peripherally acting antimuscarinic, anticholinergic agent. ... It is on the WHO Model List of Essential Medicines, the most important medications needed in a basic ... It is not a pain medication in the normal sense, since it does not directly affect pain, but rather works …
Matched Mixtures name: … BIPASMIN COMPUESTO N ... DIPIRONA N- BULTILBROMURO DE HIOSCINA ... HIOSCINA N-BUTILBROMURO+ ACETAMINOFEN GOTAS …
Matched Products: … HIOSCINA N-BUTIL BROMURO 20 MG / 1 ML ... N-BUTIL BROMURO DE HIOSCINA 20 MG/1 ML ... N-BUTIL BROMURO HIOSCINA 20 MG/1 ML SOLUCION INYECTBLE …
A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid. As the sodium salt form, sodium benzoate is used as a treatment for urea cycle disorders due to its ability to bind amino acids. This leads...
Approved
Investigational
Matched Description: … Recent research shows that sodium benzoate may be beneficial as an add-on therapy (1 gram/day) in schizophrenia ... A fungistatic compound that is widely used as a food preservative. ... This leads to excretion of these amino acids and a decrease in ammonia levels. …
Matched Salts cas: … 532-32-1 ... 2090-05-3
Matched Mixtures name: … POLY-N OINTMENT ... SAW HONG CHOON SKIN OINTMENT ... SAW HONG CHOON SKIN OINTMENT …
Matched Categories: … Compounds used in a research, industrial, or household setting …
A synthetic morphinan analgesic with narcotic antagonist action. It is used in the management of severe pain.
Approved
Illicit
Vet approved
Matched Synonyms: … (−)-N-cyclobutylmethyl-3,14-dihydroxymorphinan …
Matched Iupac: … (1S,9R,10S)-17-(cyclobutylmethyl)-17-azatetracyclo[7.5.3.0^{1,10}.0^{2,7}]heptadeca-2(7),3,5-triene-4,10 …
Matched Description: … A synthetic morphinan analgesic with narcotic antagonist action. …
Patent blue is aniline dye and it is one of the most common dyes used. It is a sodium or calcium salt of diethylammonium hydroxide inner salt. It has the chemical designation of (4-(alpha-(p-(diethylamino)phenyl)-2,4-disulfobenzylidene)-2,5-cyclohexadiene-1-ylidene)diethylammonium hydroxide. Patent blue was developed by Guerbet and approved by Health Canada on December 31, 1979....
Approved
Matched Iupac: … 4-{[4-(diethylamino)phenyl](5-hydroxy-2,4-disulfophenyl)methylidene}-N,N-diethylcyclohexa-2,5-dien-1- …
Matched Description: … [A32573] It is a sodium or calcium salt of diethylammonium hydroxide inner salt. ... chemical designation of (4-(alpha-(p-(diethylamino)phenyl)-2,4-disulfobenzylidene)-2,5-cyclohexadiene-1- …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Flunisolide (marketed as AeroBid, Nasalide, Nasarel) is a corticosteroid with anti-inflammatory actions. It is often prescribed as treatment for allergic rhinitis and its principle mechanism of action involves activation of glucocorticoid receptors.
Approved
Investigational
Matched Iupac: … (1S,2S,4R,8S,9S,11S,12S,13R,19S)-19-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo …
Matched Description: … Flunisolide (marketed as AeroBid, Nasalide, Nasarel) is a corticosteroid with anti-inflammatory actions …
Lucinactant is a new synthetic peptide-containing surfactant for intratracheal use. It contains sinapultide, a novel, hydrophobic, 21-amino acid peptide (leucine and lysine repeating units, KL4 peptide) designed to mimic human surfactant protein-B (SB-P). More specifically, it mimics the C-terminal amphipathic helical domain of this protein. It also consists of phospholipids...
Approved
Investigational
Matched Description: … , KL4 peptide) designed to mimic human surfactant protein-B (SB-P). ... Lucinactant is a new synthetic peptide-containing surfactant for intratracheal use. ... It contains sinapultide, a novel, hydrophobic, 21-amino acid peptide (leucine and lysine repeating units …
Terbutaline was first synthesized in 1966 and described in the literature in the late 1960s and early 1970s. It is a selective beta-2 adrenergic agonist used as a bronchodilator in asthmatic patients.[A230333,L32093,L32098] Terbutaline was granted FDA approval on 25 March 1974.
Approved
Matched Iupac: … 5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diol …
Matched Description: … [A230328] It is a selective beta-2 adrenergic agonist used as a bronchodilator in asthmatic patients. …
Matched Categories: … Adrenergic beta-2 Receptor Agonists ... Selective Beta 2-adrenergic Agonists …
Matched Products: … B - LENE ... บรองโคนิล (N) …
Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis (MS), and was initially approved by the FDA in 1992. Multiple Sclerosis is a devastating neurodegenerative disease that is usually progressive and significantly debilitating with a profound impact on the quality of life. Interferon...
Approved
Investigational
Matched Description: … results from infection with the novel 2019 SARS-CoV-2 virus. ... It is therefore a potential drug candidate for SARS-CoV-2 based on viral genetic similarity. ... the past in clinical studies with other coronaviruses due to its demonstrated activity against the virus
Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss. It has a significant impact on both the physical and social functioning of affected individuals.[A220318,L16408] Betahistine is a histamine-like antivertigo drug used for treating symptoms associated with Ménière's disease. It is thought to...
Approved
Investigational
Matched Synonyms: … N-methyl-2-(2-pyridinyl)ethanamine ... N-methyl-2-pyridineethanamine ... [2-(2-pyridyl)ethyl]methylamine …
Matched Iupac: … methyl[2-(pyridin-2-yl)ethyl]amine …
Matched Description: … It has a significant impact on both the physical and social functioning of affected individuals. ... Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing ... [A220318,L16408] Betahistine is a histamine-like antivertigo drug used for treating symptoms associated …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … BETAVERT N 8MG ... BETAVERT N 16MG ... BETAVERT N 24MG …
Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology and otolaryngology. Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions.
Approved
Investigational
Matched Synonyms: … 4-Amino-3-n-butoxy-benzoesäure-diäthylaminoäthylester ... 4-Amino-3-butoxy-2-(diethylamino)ethyl ester benzoic acid ... 4-Amino-3-butoxy-benzoic acid 2-diethylamino-ethyl ester …
Matched Iupac: … 2-(diethylamino)ethyl 4-amino-3-butoxybenzoate …
Matched Description: … Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology …
Matched Mixtures name: … AMIGDAL-B® …
Matched Products: … Benoxinat 1% - Lösung zur Anästhesie in der Oto-Rhino-Laryngologie …
Lifitegrast is a FDA approved drug for the treatment of keratoconjunctivitis sicca (dry eye syndrome). It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist that was discovered through the rational design process. The ophthalmic solution was approved in July, 2016 under the trade name Xiidra. It has...
Approved
Matched Iupac: … (2S)-2-{[2-(1-benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinolin-6-yl]formamido}-3-(3- …
Matched Description: … It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist ... Lifitegrast is a FDA approved drug for the treatment of keratoconjunctivitis sicca (dry eye syndrome) …
Matched Categories: … Lymphocyte Function-Associated Antigen-1 ... Lymphocyte Function-Associated Antigen-1 Antagonist ... Lymphocyte Function-Associated Antigen-1 Antagonists ... Compounds used in a research, industrial, or household setting …
Displaying drugs 426 - 450 of 6574 in total