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Displaying drugs 426 - 450 of 6316 in total

Inositol

Inositol is a collection of nine different stereoisomers but the name is usually used to describe only the most common type of inositol, myo-inositol. Myo-inositol is the cis-1,2,3,5-trans-4,6-cyclohexanehexol and it is prepared from an aqueous extract of corn kernels by precipitation and hydrolysis of crude phytate. These molecules have structural...
Approved
Investigational
Withdrawn
Matched Description: … It is considered a pseudovitamin as it is a molecule that does not qualify to be an essential vitamin ... Inositol is a collection of nine different stereoisomers but the name is usually used to describe only ... because even though its presence is vital in the body, a deficiency in this molecule does not translate …
Matched Mixtures name: … Hoa 1 ... Vege 1 Daily Tab ... For-2 …
Matched Categories: … Vitamin B Complex …

Idelalisib

Idelalisib is a phosphoinositide 3-kinase inhibitor indicated in the treatment of chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL). For the treatment of relapsed CLL, it is currently indicated as a second-line agent in combination with rituximab in patients for whom rituximab...
Approved
Matched Synonyms: … 5-Fluoro-3-phenyl-2-((S)-1-(9H-purin-6-ylamino)-propyl)-3H-quinazolin-4-one ... 5-fluoro-3-phenyl-2-[(1S)-1-(3H-purin-6-ylamino)propyl]quinazolin-4(3H)-one …
Matched Iupac: … 5-fluoro-3-phenyl-2-[(1S)-1-[(9H-purin-6-yl)amino]propyl]-3,4-dihydroquinazolin-4-one …
Matched Description: … Idelalisib is a phosphoinositide 3-kinase inhibitor indicated in the treatment of chronic lymphocytic ... specifically, idelalisib targets P110δ, the delta isoform of the enzyme phosphatidylinositol-4,5-bisphosphate 3- ... For the treatment of relapsed CLL, it is currently indicated as a second-line agent in combination with …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Phosphatidylinositol-3-kinase (Pi3K) inhibitors ... Class Ia Phosphatidylinositol 3-Kinase, antagonists & inhibitors ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …

Betahistine

Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss. It has a significant impact on both the physical and social functioning of affected individuals.[A220318,L16408] Betahistine is a histamine-like antivertigo drug used for treating symptoms associated with Ménière's disease. It is thought to...
Approved
Investigational
Matched Synonyms: … N-methyl-2-(2-pyridinyl)ethanamine ... N-methyl-2-pyridineethanamine ... [2-(2-pyridyl)ethyl]methylamine …
Matched Iupac: … methyl[2-(pyridin-2-yl)ethyl]amine …
Matched Description: … It has a significant impact on both the physical and social functioning of affected individuals. ... Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing ... [A220318,L16408] Betahistine is a histamine-like antivertigo drug used for treating symptoms associated …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … BETAVERT N 8MG ... BETAVERT N 16MG ... BETAVERT N 24MG …

Obiltoxaximab

Obiltoxaximab, an affinity-enhanced monoclonal antibody (Mab), is used for prevention and treatment of infection and death caused by anthrax toxin. Obiltoxaximab is a chimeric IgG1 kappa monoclonal antibody (mAb) that binds the PA component of B. anthracis toxin. It has an approximate molecular weight of 148 kDa.
Approved
Matched Description: … Obiltoxaximab is a chimeric IgG1 kappa monoclonal antibody (mAb) that binds the PA component of B. anthracis …
Matched Categories: … Anthrax Protective Antigen-directed Antibody ... Anthrax Protective Antigen-directed Antibody Interactions …

Bepridil

A long-acting, non selective, calcium channel blocker with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist. It is no longer marketed in the United States, as it has been implicated in causing...
Approved
Withdrawn
Matched Iupac: … N-benzyl-N-[3-(2-methylpropoxy)-2-(pyrrolidin-1-yl)propyl]aniline …
Matched Description: … A long-acting, non selective, calcium channel blocker with significant anti-anginal activity. ... It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist. …
Matched Salts cas: … 74764-40-2 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Flunisolide

Flunisolide (marketed as AeroBid, Nasalide, Nasarel) is a corticosteroid with anti-inflammatory actions. It is often prescribed as treatment for allergic rhinitis and its principle mechanism of action involves activation of glucocorticoid receptors.
Approved
Investigational
Matched Iupac: … (1S,2S,4R,8S,9S,11S,12S,13R,19S)-19-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo …
Matched Description: … Flunisolide (marketed as AeroBid, Nasalide, Nasarel) is a corticosteroid with anti-inflammatory actions …

Isosulfan blue

Approved
Matched Iupac: … 4-{[4-(diethylamino)phenyl](2,5-disulfophenyl)methylidene}-N,N-diethylcyclohexa-2,5-dien-1-iminium …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Lymphazurin 1% …

Chloroquine

Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. Chloroquine and its derivative hydroxychloroquine have since been repurposed for the treatment of a...
Approved
Investigational
Vet approved
Matched International brands: … Nivaquine B …
Matched Iupac: … 7-chloro-N-[5-(diethylamino)pentan-2-yl]quinolin-4-amine …
Matched Description: … Chloroquine and its derivative [hydroxychloroquine] have since been repurposed for the treatment of a …
Matched Salts cas: … 3545-67-3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Insulin beef

Insulin beef has been discontinued in the US and Canada since 2017.
Approved

Rifaximin

Rifaximin is a semisynthetic, rifamycin-based non-systemic antibiotic, meaning that the drug will not pass the gastrointestinal wall into the circulation as is common for other types of orally administered antibiotics. It has multiple indications and is used in treatment of traveller's diarrhea caused by E. coli; reduction in risk of...
Approved
Investigational
Matched Iupac: … (7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17,36-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22,30 …
Matched Description: … Rifaximin is a semisynthetic, rifamycin-based non-systemic antibiotic, meaning that the drug will not …
Matched Products: … RIFAXIMINA 2% ... RIFAXIGAL® 100MG/5ML POLVO PARA RECONSTITUIR A SUSPENSION ORAL ... RIFAX 2% - POLVO PARA RECONSTITUIR SUSPENSIONORAL …

Oxybuprocaine

Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology and otolaryngology. Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions.
Approved
Investigational
Matched Synonyms: … 4-Amino-3-n-butoxy-benzoesäure-diäthylaminoäthylester ... 4-Amino-3-butoxy-2-(diethylamino)ethyl ester benzoic acid ... 4-Amino-3-butoxy-benzoic acid 2-diethylamino-ethyl ester …
Matched Iupac: … 2-(diethylamino)ethyl 4-amino-3-butoxybenzoate …
Matched Description: … Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology …
Matched Mixtures name: … AMIGDAL-B® …
Matched Products: … Benoxinat 1% - Lösung zur Anästhesie in der Oto-Rhino-Laryngologie …

Prednisone

A synthetic anti-inflammatory glucocorticoid derived from cortisone. It is biologically inert and converted to prednisolone in the liver. Prednisone was granted FDA approval on 21 February 1955.
Approved
Vet approved
Matched Iupac: … (1R,3aS,3bS,9aR,9bS,11aS)-1-hydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH ... ,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene-7,10-dione …
Matched Description: … A synthetic anti-inflammatory glucocorticoid derived from [cortisone]. …
Matched Products: … ROMEZON DR 2 MG TABLET, 30 ADET ... ROMEZON DR 1 MG TABLET, 30 ADET ... LODOTRA® 1 MG TABLETAS DE CRONO LIBERACION MODIFICADA …

Sodium zirconium cyclosilicate

Sodium zirconium cyclosilicate is approved as the trade product Lokelma developed by AstraZeneca - an insoluble, non-absorbed sodium zirconium silicate, formulated as a powder for oral suspension that acts as a highly selective potassium removing agent. It is administered orally and is odorless, tasteless, and stable at room temperature. Approval...
Approved
Investigational
Matched Description: … powder for oral suspension that acts as a highly selective potassium removing agent. ... Lokelma developed by AstraZeneca - an insoluble, non-absorbed sodium zirconium silicate, formulated as a …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … SIMKELMA 5 G ORAL SÜSPANSİYON HAZIRLAMAK İÇİN TOZ, 11 ADET ... SIMKELMA 10 G ORAL SÜSPANSİYON HAZIRLAMAK İÇİN TOZ, 11 ADET …

Acetylcysteine

Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of acetaminophen overdose.[L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.[A228158,A228163,A228168] Acetylcysteine was granted FDA approval on 14 September 1963.
Approved
Investigational
Matched Synonyms: … (2R)-2-acetylamino-3-sulfanylpropanoic acid ... (R)-2-acetylamino-3-mercaptopropanoic acid ... N-acetylcysteine …
Matched Iupac: … (2R)-2-acetamido-3-sulfanylpropanoic acid …
Matched Description: … [L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications …
Matched Mixtures name: … AMINOSTERIL N-HEPA 500 ML SOLUSYON ... N-ACETILCISTEÍNA MAS GUAYACOLATO DE GLICERILO …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … N-ACETILCISTEÍNA 2 G / 100 ML JARABE ... ACETILCISTEINAJARABE AL 2%.POLVO PARA RECONSTITUIR A SOLUCIÓN ORAL ... N-ACETILCISTEINA 300 MG/3 ML …

Fezolinetant

Vasomotor symptoms (VMS), more colloquially known as hot flashes or night sweats, are some of the most common symptoms in menopause. With a median duration of 7.4 years, vasomotor symptoms are also the most common reasons why women seek treatments for menopausal issues.[A259591,A259596] Although mostly considered a nuisance, vasomotor symptoms...
Approved
Investigational
Matched Iupac: … 5-[(8R)-7-(4-fluorobenzoyl)-8-methyl-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]-3-methyl-1,2,4-thiadiazole …
Matched Description: … the kisspeptin, neurokinin B, and dynorphin (KNDy) neurons. ... [A259591,A259542] NK3, one of the receptors expressed in KNDy neurons, is activated by neurokinin B and ... estrogen levels during menopause will decrease the estrogen-mediated feedback loop and increase neurokinin B …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Neurokinin 3 Receptor Antagonist …

Oxygen

Oxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy. Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing blood flow...
Approved
Vet approved
Matched Description: … Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing …
Matched Mixtures name: … Carbon Dioxide 1% W Oxygen …
Matched Products: … N/A ... Oxygen Size B ... Oxygen Size H …

Benzphetamine

A sympathomimetic agent with properties similar to dextroamphetamine. It is used in the treatment of obesity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1222)
Approved
Illicit
Matched Synonyms: … N-methyl-1-phenyl-N-(phenylmethyl)propan-2-amine ... (+)-N-benzyl-N,α-dimethylphenethylamine ... (S)-(+)-N-benzyl-N,α-dimethylphenethylamine …
Matched Iupac: … benzyl(methyl)[(2S)-1-phenylpropan-2-yl]amine …
Matched Description: … A sympathomimetic agent with properties similar to dextroamphetamine. …
Matched Salts cas: … 5411-22-3 …
Matched Categories: … Adrenergic alpha-1 Receptor Agonists …

Brilliant green cation

Brilliant green, or ethanaminium, is a derivative of triarylmethane dye that has been used as a dye to color silk and wool. Due to its inhibitory actions against Gram positive microorganisms, brilliant green can be found in antiseptic products such as solutions and swabs used to prevent infection.
Approved
Vet approved
Matched Synonyms: … Brilliant green(1+) …
Matched Iupac: … 4-{[4-(diethylamino)phenyl](phenyl)methylidene}-N,N-diethylcyclohexa-2,5-dien-1-iminium …
Matched Description: … Brilliant green, or ethanaminium, is a derivative of triarylmethane dye that has been used as a dye to …
Matched Mixtures name: … Kerr 100 Triple Dye Dispos-A …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Sodium borate

Approved
Experimental

Ansuvimab

Infection with pathogenic filoviruses, such as Zaire ebolavirus (Ebola virus, EBOV), can cause severe hemorrhagic fever in humans, resulting in frequent outbreaks with case fatality rates as high as 90%.[A225933, A225938] Virtually all steps of the EBOV lifecycle have been targeted for therapeutic development. However, to date, the most successful...
Approved
Investigational
Matched Description: … virus disease (EVD) in the Democratic Republic of Congo during a previous outbreak that began in 2018 ... EBOV outbreak 11 years after infection, which displays strong glycan-independent binding to a conserved ... Infection with pathogenic filoviruses, such as _Zaire ebolavirus_ (Ebola virus, EBOV), can cause severe …
Matched Categories: … Treatments for Ebola Virus Disease …

Desonide

A nonfluorinated corticosteroid anti-inflammatory agent used topically for dermatoses.
Approved
Investigational
Matched Synonyms: … 11β,21-dihydroxy-16α,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione …
Matched Iupac: … (1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[ …
Matched Description: … A nonfluorinated corticosteroid anti-inflammatory agent used topically for dermatoses. …
Matched Mixtures name: … APOLAR N ... DESOLEX-N ... MEPROLAR-N …

Synthetic Conjugated Estrogens, A

Synthetic conjugated estrogens A are composed of a blend of the following nine synthetic estrogenic substances: estrone sulfate, sodium equilin sulfate, sodium 17α-dihydroequilin sulfate, sodium 17α-estradiol sulfate, sodium 17β­ dihydroequilin sulfate, sodium 17α-dihydroequilenin sulfate, sodium 17β-dihydroequilenin sulfate, sodium equilenin sulfate, and sodium 17β-estradiol sulfate. This blend of nine estrogen derivatives...
Approved
Matched Synonyms: … Estrogens, Conjugated Synthetic A …
Matched Name: … Synthetic Conjugated Estrogens, A …
Matched Description: … as Cenestin) or as "Synthetic Conjugated Estrogens, B" containing 10 estrogen derivatives (available ... Synthetic conjugated estrogens A are composed of a blend of the following nine synthetic estrogenic substances ... However, once a woman stops ovulating there is a sharp decline in the production of progesterone and …

Cefmetazole

A semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms. It has a high rate of efficacy in many types of infection and to date no severe side effects have been noted.
Approved
Investigational
Matched Synonyms: … }-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7S)-7-({[(cyanomethyl)sulfanyl]acetyl}amino)-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl …
Matched Iupac: … (6R,7S)-7-{2-[(cyanomethyl)sulfanyl]acetamido}-7-methoxy-3-{[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl ... ]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … A semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and ... It has a high rate of efficacy in many types of infection and to date no severe side effects have been …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Palivizumab

Humanized monoclonal antibody (IgG1k) produced by recombinant DNA technology, directed to an epitope in the A antigenic site of the F protein of respiratory syncytial virus (RSV). Synagis is a composite of human (95%) and murine (5%) antibody sequences. The human heavy chain sequence was derived from the constant domains...
Approved
Investigational
Matched Description: … 2% carbohydrate by weight and has a molecular weight of 147.7 kDa +/- 1 kDa (MALDI-TOF) ... and Cess (2). ... antigenic site of the F protein of respiratory syncytial virus (RSV). …
Matched Categories: … Respiratory Syncytial Virus Anti-F Protein Monoclonal Antibody …
Matched Products: … SYNAGIS 100 MG/1 ML IM ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON,1 ADET ... SYNAGIS 100 MG/1 ML IM ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON, 1 ADET ... SYNAGIS 100 ML IM ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON,1 ADET …

Latanoprostene bunod

Latanoprostene Bunod has been used in trials studying the treatment of Glaucoma, Ocular Hypertension, Open-Angle Glaucoma, Open Angle Glaucoma, and Intraocular Pressure. As of November 2, 2017 the FDA approved Bausch + Lomb's Vyzulta (latanoprostene bunod opthalmic solution), 0.024% for the indication of reducing intraocular pressure in patients with open-angle...
Approved
Investigational
Matched Iupac: … 4-(nitrooxy)butyl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept …
Matched Description: … In comparison, both latanoprost and latanoprostene bunod contain a latanoprost acid backbone. ... As of November 2, 2017 the FDA approved Bausch + Lomb's Vyzulta (latanoprostene bunod opthalmic solution …
Displaying drugs 426 - 450 of 6316 in total