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Displaying drugs 426 - 450 of 14373 in total

Methoxsalen

A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA adducts in the presence of ultraviolet A irradiation.
Approved
Matched Categories: … Indicators and Reagents …

Vinblastine

Antitumor alkaloid isolated from Vinca rosea. (Merck, 11th ed.)
Approved
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Galantamine

Galantamine is a tertiary alkaloid and reversible, competitive inhibitor of the acetylcholinesterase (AChE) enzyme, which is a widely studied therapeutic target used in the treatment of Alzheimer's disease. First characterized in the early 1950s, galantamine is a tertiary alkaloid that was extracted from botanical sources, such as Galanthus nivalis. Galantamine...
Approved
Matched Description: … and extended-release tablets and solution. ... [A201968] Galantamine was first studied in paralytic and neuropathic conditions, such as myopathies and ... until the early 1990s due to difficulties in extraction and synthesis. …

Warfarin

Warfarin is an anticoagulant drug normally used to prevent blood clot formation as well as migration. Although originally marketed as a pesticide (d-Con, Rodex, among others), Warfarin has since become the most frequently prescribed oral anticoagulant in North America. Warfarin has several properties that should be noted when used medicinally,...
Approved
Matched Description: … , and drug interactions have also been documented with warfarin use. ... during pregnancy which can result in fetal bleeding, spontaneous abortion, preterm birth, stillbirth, and ... Additional adverse effects such as necrosis, purple toe syndrome, osteoporosis, valve and artery calcification …
Matched Categories: … Warfarin and isomers ... Blood and Blood Forming Organs …

Daunorubicin

A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of leukemia and other neoplasms.
Approved
Matched Description: … , used in treatment of leukemia and other neoplasms. ... A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others …
Matched Categories: … cytarabine and daunorubicin ... Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …

Irinotecan

Irinotecan is a topoisomerase inhibitor used for chemotherapy. It is a water-soluble analogue of camptothecin, which is extracted from the Chinese tree Camptotheca acuminate. The bis-piperidine side chain in the structure of irinotecan bestows enhanced water solubility. As an anticancer drug, irinotecan was first commercially available in Japan in 1994...
Approved
Investigational
Matched Description: … Both irinotecan and SN-38 mediate antitumor activity by forming a complex with topoisomerase I and blocking ... This leads to the arrest of the cell cycle in the S-G2 phase and cancer cell death.[A263376] ... [A263376] Approved by the FDA in 1996,[A263366] irinotecan is used to treat colorectal cancer and pancreatic …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Minocycline

Minocycline was first described in the literacture in 1966. It is a second generation tetracycline antibiotic that is active against gram-negative and gram-positive bacteria. Like other semisynthetic tetracyclines, minocycline has modifications to carbons 7-9 on the D ring to generate higher efficacy than previous tetracyclines. Minocycline was granted FDA approval...
Approved
Investigational
Matched Description: … [A190681] It is a second generation tetracycline antibiotic that is active against gram-negative and …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinfectives and Antiseptics for Local Oral Treatment …

Topotecan

An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA topoisomerases, type I.
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Rifampin

Rifampin, also known as rifampicin, is a broad-spectrum antimicrobial that was first discovered in 1965 and clinically used in 1968. Rifampin is used to treat tuberculosis and works by inhibiting the microbial DNA-dependent RNA polymerase (RNAP).
Approved
Matched Description: … rifampicin, is a broad-spectrum antimicrobial [A263748] that was first discovered in 1965 [A263753] and ... [A263768] Rifampin is used to treat tuberculosis and works by inhibiting the microbial DNA-dependent …
Matched Categories: … dapsone and rifampicin ... rifampicin and isoniazid ... dapsone, rifampicin and clofazimine ... rifampicin, ethambutol and isoniazid ... rifampicin, pyrazinamide and isoniazid …

Yohimbine

A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.
Approved
Investigational
Vet approved
Matched Description: … Yohimbine has been used as a mydriatic and in the treatment of impotence. …
Matched Categories: … Genito Urinary System and Sex Hormones …

Everolimus

Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor. It is currently used as an immunosuppressant to prevent rejection of organ transplants. In a similar fashion to other mTOR inhibitors Everolimus' effect is solely on the mTORC1 protein and...
Approved
Matched Description: … Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian ... In a similar fashion to other mTOR inhibitors Everolimus' effect is solely on the mTORC1 protein and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Maraviroc

Maraviroc (brand-named Selzentry, or Celsentri outside the U.S.) is a chemokine receptor antagonist drug developed by the drug company Pfizer that is designed to act against HIV by interfering with the interaction between HIV and CCR5. It was originally labelled as UK-427857 during development but was assigned the Maraviroc name...
Approved
Investigational
Matched Description: … company Pfizer that is designed to act against HIV by interfering with the interaction between HIV and …

Elafibranor

Elafibranor is a dual peroxisome proliferator-activated receptor (PPAR) α and β/δ agonist. On June 10, 2024, elafibranor was granted accelerated approval by the FDA for the treatment of primary biliary cholangitis (PBC).
Approved
Investigational
Matched Description: … Elafibranor is a dual peroxisome proliferator-activated receptor (PPAR) α and β/δ agonist. …
Matched Categories: … Bile and Liver Therapy ... Alimentary Tract and Metabolism …

Temsirolimus

Temsirolimus is a derivative of sirolimus used in the treatment of renal cell carcinoma (RCC). It was developed by Wyeth Pharmaceuticals under the trade name Torisel. Temsirolimus was approved by the FDA in late May 2007 as well as the European Medicines Agency (EMEA) on November 2007.
Approved
Matched Categories: … Sirolimus and Prodrugs ... Antineoplastic and Immunomodulating Agents …

Streptococcus pneumoniae type 1 capsular polysaccharide antigen

Streptococcus pneumoniae type 1 capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 1 of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Matched Description: … intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and …

Streptococcus pneumoniae type 3 capsular polysaccharide antigen

Streptococcus pneumoniae type 3 capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 3 of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Description: … intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and …

Streptococcus pneumoniae type 4 capsular polysaccharide antigen

Streptococcus pneumoniae type 4 capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 4 of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Description: … intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and …

Streptococcus pneumoniae type 5 capsular polysaccharide antigen

Streptococcus pneumoniae type 5 capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 5 of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Description: … intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and …

Streptococcus pneumoniae type 8 capsular polysaccharide antigen

Streptococcus pneumoniae type 8 capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 8 of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Description: … intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and …

Streptococcus pneumoniae type 14 capsular polysaccharide antigen

Streptococcus pneumoniae type 14 capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 14 of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Description: … intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and …

Streptococcus pneumoniae type 6a capsular polysaccharide antigen

Approved
Experimental

Somatrem

Despite the ability of almost all contemporary recombinant growth hormones to cause definite and demonstrable increases in growth rate in patients who are administered the drug, the use of these agents continues to be mired in persistent bioethical debate . Such discussion revolves around whether patients' natural disposition of short...
Approved
Investigational
Withdrawn
Matched Description: … Despite the ability of almost all contemporary recombinant growth hormones to cause definite and demonstrable …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Somatropin and Somatropin Agonists ... Anterior Pituitary Lobe Hormones and Analogues …

Streptococcus pneumoniae type 11a capsular polysaccharide antigen

Streptococcus pneumoniae type 11a capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 11a of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Description: … intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and …

Streptococcus pneumoniae type 12f capsular polysaccharide antigen

Streptococcus pneumoniae type 12f capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 12f of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Description: … intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and …

Streptococcus pneumoniae type 17f capsular polysaccharide antigen

Streptococcus pneumoniae type 17f capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 17f of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Description: … intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and …
Displaying drugs 426 - 450 of 14373 in total