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Displaying drugs 4651 - 4675 of 11336 in total
A noncompetitive antagonist at GABA-A receptors and thus a convulsant. Picrotoxin blocks the gamma-aminobutyric acid-activated chloride ionophore. Although it is most often used as a research tool, it has been used as a CNS stimulant and an antidote in poisoning by CNS depressants, especially the barbiturates. [PubChem]
Experimental
Matched Description: … A noncompetitive antagonist at GABA-A receptors and thus a convulsant. ... Although it is most often used as a research tool, it has been used as a CNS stimulant and an antidote …
Matched Categories: … GABA-A Receptor Antagonists ... Compounds used in a research, industrial, or household setting …
Experimental
Matched Iupac: … ,9bS,11aS)-8-methoxy-11a-methyl-7-(sulfamoyloxy)-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a] …
Investigational
Matched Iupac: … carbamimidamidopropyl)-3-(cyclohexylmethyl)-6-[(1H-indol-3-yl)methyl]-1,4,7,10,16-pentaoxo-icosahydropyrrolo[1,2-a] …
Nitrilotriacetic acid is a derivative of acetic acid, N(CH2COOH)3. It is a complexing (sequestering) agent that forms stable complexes with Zn2+. (From Miall's Dictionary of Chemistry, 5th ed.)
Experimental
Matched Description: … Nitrilotriacetic acid is a derivative of acetic acid, N(CH2COOH)3. ... It is a complexing (sequestering) agent that forms stable complexes with Zn2+. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Thenoyltrifluoroacetone is a chelating agent and inhibitor of cellular respiration.
Experimental
Matched Description: … Thenoyltrifluoroacetone is a chelating agent and inhibitor of cellular respiration. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Icaridin, also known as Picaridin or hydroxy-ethyl isobutyl piperidine carboxylate, is a cyclic amine and a member of the piperidine chemical family. Piperidines are structural components of piperine, which is a plant extract from the genus _Piper _, or pepper. Icaridin has been commonly used as a topically-applied insect repellent...
Experimental
Matched Description: … and a member of the piperidine chemical family. ... Icaridin, also known as Picaridin or hydroxy-ethyl isobutyl piperidine carboxylate, is a cyclic amine ... Piperidines are structural components of [piperine], which is a plant extract from the genus _Piper _ …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
TAK-448 has been used in trials studying the treatment of Prostate Cancer, Low Testosterone, Prostatic Neoplasms, and Hypogonadotropic Hypogonadism.
Investigational
An oxyacid of chlorine (HClO) containing monovalent chlorine that acts as an oxidizing or reducing agent.
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
SGS-742 has been used in trials studying the treatment of Seizures and Metabolic Disease.
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
EP0057 is a conjugate of Insert's proprietary drug delivery molecule, Cyclosert, and the potent anti-cancer compound camptothecin.
Investigational
Matched Description: … EP0057 is a conjugate of Insert's proprietary drug delivery molecule, Cyclosert, and the potent anti-cancer …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
A166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) site-specifically conjugated to an anti-HER2 antibody (trastuzumab) via a stable protease-cleavable valine citrulline linker.
Investigational
Matched Description: … A166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) ... site-specifically conjugated to an anti-HER2 antibody (trastuzumab) via a stable protease-cleavable …
Digitoxigenin is a cardenolide which is the aglycon of digitoxin.
Experimental
Matched Iupac: … 4-[(1R,3aS,3bR,5aR,7S,9aS,9bS,11aR)-3a,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren …
Matched Description: … Digitoxigenin is a cardenolide which is the aglycon of digitoxin. …
Experimental
Matched Iupac: … (1R,3aS,3bS,11aS)-1-ethynyl-1-hydroxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,11aH-cyclopenta[a]phenanthren …
BMS-813160 is under investigation in clinical trial NCT03496662 (BMS-813160 With Nivolumab and Gemcitabine and Nab-paclitaxel in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma (PDAC)).
Investigational
Matched Iupac: … N-[(1R,2S,5R)-5-(tert-butylamino)-2-[(3S)-3-({7-tert-butylpyrazolo[1,5-a][1,3,5]triazin-4-yl}amino)-2 …
Investigational
Matched Iupac: … N-{[4-(1-methyl-1H-pyrazol-4-yl)phenyl]methyl}-6-{7-[3-(pyrrolidin-1-yl)propoxy]imidazo[1,2-a]pyridin …
Investigational
Matched Iupac: … (1S,3aS,3bR,9bS,11aS)-1-hydroxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthren …
Experimental
Matched Iupac: … (3aS,3bR,9aR,9bS,11aS)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene …
Experimental
Matched Iupac: … ,3bS,9bR,10S,11aS)-10-(methoxymethyl)-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a] …
Bicifadine (DOV-220075) is a nonopioid analgesic. It is an inhibitor of both the norepinephrine and serotonin transporters and an NMDA antagonist with a non-narcotic profile. Bicifadine was shown to have potent analgesic activity in vivo and was chosen for further development for the treatment of pain.
Investigational
Matched Description: … Bicifadine (DOV-220075) is a nonopioid analgesic. ... It is an inhibitor of both the norepinephrine and serotonin transporters and an NMDA antagonist with a
Matched Categories: … Monoamine Oxidase A Substrates …
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
Displaying drugs 4651 - 4675 of 11336 in total