Displaying drugs 451 - 475 of 841 in total
Methyl vanillate
Experimental
Matched Synonyms: … 4-hydroxy-3-methoxy methyl benzoate …
Matched Categories: … Benzoates …
Matched Categories: … Benzoates …
4-(ACETYLAMINO)-5-AMINO-3-HYDROXYBENZOIC ACID
Experimental
Matched Name: … 4-(ACETYLAMINO)-5-AMINO-3-HYDROXYBENZOIC ACID …
Matched Iupac: … 3-amino-4-acetamido-5-hydroxybenzoic acid …
Matched Iupac: … 3-amino-4-acetamido-5-hydroxybenzoic acid …
Dacarbazine
An antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564). Dacarbazine with Oblimersen is in clinical trials for the treatment of malignant melanoma.
Approved
Investigational
Matched Synonyms: … 4-(3,3-dimethyl-1-triazeno)imidazole-5-carboxamide ... 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide ... 4-(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Triazenes …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Triazenes …
PHOSPHONIC ACID 2-DODECANOYLAMINO-HEXYL ESTER PROPYL ESTER
Experimental
Matched Name: … PHOSPHONIC ACID 2-DODECANOYLAMINO-HEXYL ESTER PROPYL ESTER …
Uric acid
Uric acid is the last product of purine metabolism in humans. The formation of uric acid is through the enzyme xanthine oxidase, which oxidizes oxypurines. Normally a small amount of uric acid is present in the body, but when there is an excess amount in the blood, called hyperuricemia, this...
Investigational
Matched Synonyms: … Purine-2,6,8(1H,3H,9H)-trione ... 7,9-dihydro-1H-purine-2,6,8(3H)-trione …
Matched Iupac: … 2,3,6,7,8,9-hexahydro-1H-purine-2,6,8-trione …
Matched Description: … body, but when there is an excess amount in the blood, called hyperuricemia, this can lead to gout and ... As a therapeutic agent, it is known that uric acid is increased in response to oxidative stress, and …
Matched Iupac: … 2,3,6,7,8,9-hexahydro-1H-purine-2,6,8-trione …
Matched Description: … body, but when there is an excess amount in the blood, called hyperuricemia, this can lead to gout and ... As a therapeutic agent, it is known that uric acid is increased in response to oxidative stress, and …
Estazolam
A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. It has been shown in some cases to be more potent than diazepam or nitrazepam.
Approved
Illicit
Matched Synonyms: … 8-chloro-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine …
Matched Description: … A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. …
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Hypnotics and Sedatives ... Benzodiazepines and benzodiazepine derivatives …
Matched Description: … A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. …
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Hypnotics and Sedatives ... Benzodiazepines and benzodiazepine derivatives …
2-AMINO-4-CHLORO-3-HYDROXYBENZOIC ACID
Experimental
Matched Name: … 2-AMINO-4-CHLORO-3-HYDROXYBENZOIC ACID …
Matched Iupac: … 2-amino-4-chloro-3-hydroxybenzoic acid …
Matched Iupac: … 2-amino-4-chloro-3-hydroxybenzoic acid …
(3S,6S)-3,6-bis(4-hydroxybenzyl)piperazine-2,5-dione
Experimental
Matched Name: … (3S,6S)-3,6-bis(4-hydroxybenzyl)piperazine-2,5-dione …
Benzoylecgonine
Benzoylecgonine is the major metabolite of cocaine. It is formed by hydrolysis of cocaine in the liver, catalysed by carboxylesterases. It is excreted in the urine of cocaine users after processing in the liver. It is the main pharmaceutical ingredient in the investigational drug Esterom, a topical solution used for...
Experimental
Illicit
Matched Synonyms: … Ecgonine benzoate …
Tesamorelin
Tesamorelin is a stabilized synthetic peptide analogue of the hypothalamic peptide, Growth Hormone Releasing Hormone (GHRH) indicated for the reduction of excess abdominal fat in HIV-infected patients with lipodystrophy. Lipodystrophy is a metabolic condition characterized by insulin resistance, fat redistribution, and hyperlipidemia associated with antiretroviral therapy for HIV infection.
Approved
Investigational
Matched Synonyms: … N-[(3E)-1-oxo-3-hexenyl]Somatoliberin (human pancreatic islet) …
Matched Description: … Lipodystrophy is a metabolic condition characterized by insulin resistance, fat redistribution, and hyperlipidemia …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Anterior Pituitary Lobe Hormones and Analogues ... Sex Hormones and Insulins ... Somatropin and Somatropin Agonists …
Matched Description: … Lipodystrophy is a metabolic condition characterized by insulin resistance, fat redistribution, and hyperlipidemia …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Anterior Pituitary Lobe Hormones and Analogues ... Sex Hormones and Insulins ... Somatropin and Somatropin Agonists …
Candesartan
Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is available as a prodrug in the form of candesartan cilexetil.
Experimental
Matched Categories: … candesartan and diuretics ... candesartan and amlodipine ... Angiotensin II receptor blockers (ARBs) and diuretics ... atorvastatin, amlodipine and candesartan ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers …
Matched Products: … CANDESARTAN HEXAL ... CANDESARTAN HEXAL 4MG TAB ... CANDESARTAN HEXAL 8MG TAB …
Matched Products: … CANDESARTAN HEXAL ... CANDESARTAN HEXAL 4MG TAB ... CANDESARTAN HEXAL 8MG TAB …
Ergotamine
A vasoconstrictor found in ergot of Central Europe. It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders.
Approved
Matched Synonyms: … (5'α)-12'-hydroxy-2'-methyl-5'-(phenylmethyl)ergotoman-3',6',18-trione ... 12'-hydroxy-2'-methyl-5'α-(phenylmethyl)ergotaman-3',6',18-trione ... 12'-Hydroxy-2'-methyl-5'alpha-(phenylmethyl)ergotaman-3',6',18-trione …
Matched Description: … It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders …
Matched Mixtures name: … Ergotamine Tartrate and Caffeine ... Ergotamine Tartrate and Caffeine ... Ergotamine Tartrate and Caffeine …
Matched Categories: … Ergot Alkaloids and Derivatives …
Matched Description: … It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders …
Matched Mixtures name: … Ergotamine Tartrate and Caffeine ... Ergotamine Tartrate and Caffeine ... Ergotamine Tartrate and Caffeine …
Matched Categories: … Ergot Alkaloids and Derivatives …
AMG-208
AMG-208 has been used in trials studying the treatment of Cancer, Tumors, Oncology, Prostate Cancer, and Oncology Patients, among others.
Investigational
Matched Synonyms: … 7-methoxy-4-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy]quinoline …
Matched Iupac: … 7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl}methoxy)quinoline …
Matched Description: … AMG-208 has been used in trials studying the treatment of Cancer, Tumors, Oncology, Prostate Cancer, and …
Matched Iupac: … 7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl}methoxy)quinoline …
Matched Description: … AMG-208 has been used in trials studying the treatment of Cancer, Tumors, Oncology, Prostate Cancer, and …
Alprazolam
Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders.[L34783, L34788] It is mainly metabolized by CYP3As and so is contraindicated with CYP3A inhibitors like ketoconazole and itraconazole.[L34783, L34788] Benzodiazepine treatment should be stopped gradually by tapering down a patient's dose to avoid withdrawal symptoms. Alprazolam's adverse...
Approved
Illicit
Investigational
Matched Synonyms: … 8-Chloro-1-methyl-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine …
Matched Description: … ketoconazole and itraconazole. ... Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders. ... [L34783, L34788] It is mainly metabolized by CYP3As and so is contraindicated with CYP3A inhibitors like …
Matched Categories: … Benzodiazepines and benzodiazepine derivatives ... Hypnotics and Sedatives …
Matched Products: … ALPRAZOLAM HEXAL AG …
Matched Description: … ketoconazole and itraconazole. ... Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders. ... [L34783, L34788] It is mainly metabolized by CYP3As and so is contraindicated with CYP3A inhibitors like …
Matched Categories: … Benzodiazepines and benzodiazepine derivatives ... Hypnotics and Sedatives …
Matched Products: … ALPRAZOLAM HEXAL AG …
TAK-603
Investigational
Matched Synonyms: … Ethyl 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-(1,2,4-triazol-1-ylmethyl)quinoline-3-carboxylate ... 3-quinolinecarboxylic acid, 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-(1h-1,2,4-triazol-1-ylmethyl)-, ethyl …
Matched Iupac: … ethyl 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-[(1H-1,2,4-triazol-1-yl)methyl]quinoline-3-carboxylate …
Matched Iupac: … ethyl 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-[(1H-1,2,4-triazol-1-yl)methyl]quinoline-3-carboxylate …
Ochromycinone
Ochromycinone is under investigation in clinical trial NCT01047943 (STA-21 Topical Efficacy on Psoriasis).
Investigational
Matched Synonyms: … -methyl-8-hydroxy-1,2,3,4,7,12-hexahydrobenzo(a)anthracene-1,7,12-trione ... Benz(a)anthracene-1,7,12(2h)-trione, 3,4-dihydro-8-hydroxy-3-methyl-, (s)- …
Matched Iupac: … (3S)-8-hydroxy-3-methyl-1,2,3,4,7,12-hexahydrotetraphene-1,7,12-trione …
Matched Iupac: … (3S)-8-hydroxy-3-methyl-1,2,3,4,7,12-hexahydrotetraphene-1,7,12-trione …
Resmetirom
Resmetirom is a thyroid hormone receptor-beta (THR-beta) agonist. On March 14, 2024, it was approved by the FDA as the first treatment of liver fibrosis due to noncirrhotic non-alcoholic steatohepatitis (NASH), which is a form of non-alcoholic fatty liver disease (NAFLD). Thyroid hormones directly regulate lipid metabolism in the liver;...
Approved
Investigational
Matched Synonyms: … 1,2,4-Triazine-6-carbonitrile, 2-[3,5-dichloro-4-[[1,6-dihydro-5-(1-methylethyl)-6-oxo-3-pyridazinyl] ... -[[1,6-dihydro-5-(1-methylethyl)-6-oxo-3-pyridazinyl]oxy]phenyl]-2,3,4,5-tetrahydro-3,5-dioxo-1,2,4-triazine …
Matched Iupac: … -4-{[6-oxo-5-(propan-2-yl)-1,6-dihydropyridazin-3-yl]oxy}phenyl)-3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine …
Matched Description: … [A263461] Resmetirom works to reduce liver fat by stimulating fatty acid degradation and oxidation. …
Matched Iupac: … -4-{[6-oxo-5-(propan-2-yl)-1,6-dihydropyridazin-3-yl]oxy}phenyl)-3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine …
Matched Description: … [A263461] Resmetirom works to reduce liver fat by stimulating fatty acid degradation and oxidation. …
LAS-191954
Investigational
Matched Synonyms: … Pyrrolo(2,1-f)(1,2,4)triazine-5-carbonitrile, 2-((1s)-1-((6-amino-5-cyano-4-pyrimidinyl)amino)ethyl)- ... ((1s)-1-((6-amino-5-cyano-4-pyrimidinyl)amino)ethyl)-3,4-dihydro-4-oxo-3-phenylpyrrolo(2,1-f)(1,2,4)triazine …
Matched Iupac: … 4-amino-6-{[(1S)-1-{5-cyano-4-oxo-3-phenyl-3H,4H-pyrrolo[2,1-f][1,2,4]triazin-2-yl}ethyl]amino}pyrimidine …
Matched Iupac: … 4-amino-6-{[(1S)-1-{5-cyano-4-oxo-3-phenyl-3H,4H-pyrrolo[2,1-f][1,2,4]triazin-2-yl}ethyl]amino}pyrimidine …
5,6-dihydro-5-azacytidine
Investigational
Matched Synonyms: … 1,3,5-triazin-2(1h)-one, 4-amino-5,6-dihydro-1-.beta.-d-ribofuranosyl- …
Matched Iupac: … 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,5,6-tetrahydro-1,3,5-triazin …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,5,6-tetrahydro-1,3,5-triazin …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Pentetic acid
Pentetic acid, also known as diethylenetriaminepentaacetic acid (DTPA), is a synthetic polyamino carboxylic acid with eight coordinate bond forming sites that can sequester metal ions and form highly stable DTPA-metal ion complexes. DTPA, along with its calcium and zinc trisodium salts, are the only FDA approved agents for the treatment...
Approved
Matched Synonyms: … Diethylene triamine pentaacetic acid …
Matched Description: … synthetic polyamino carboxylic acid with eight coordinate bond forming sites that can sequester metal ions and ... DTPA, along with its calcium and zinc trisodium salts, are the only FDA approved agents for the treatment ... [L2242] DPTA was developed by the pharmaceutical company CIS US and FDA approved on April 14, 2004. …
Matched Description: … synthetic polyamino carboxylic acid with eight coordinate bond forming sites that can sequester metal ions and ... DTPA, along with its calcium and zinc trisodium salts, are the only FDA approved agents for the treatment ... [L2242] DPTA was developed by the pharmaceutical company CIS US and FDA approved on April 14, 2004. …
6-(2-phenoxyethoxy)-1,3,5-triazine-2,4-diamine
Experimental
Matched Name: … 6-(2-phenoxyethoxy)-1,3,5-triazine-2,4-diamine …
Matched Iupac: … 6-(2-phenoxyethoxy)-1,3,5-triazine-2,4-diamine …
Matched Iupac: … 6-(2-phenoxyethoxy)-1,3,5-triazine-2,4-diamine …
Hexasodium phytate
Investigational
Matched Synonyms: … (1r,2r,3s,4s,5r,6s)-cyclohexane-1,2,3,4,5,6-hexayl-hexakis(dihydrogen phosphate) …
DSM-265
DSM265 has been used in trials studying the prevention and treatment of Malaria.
Investigational
Matched Synonyms: … 2-(1,1-difluoroethyl)-5-methyl-N-[4-(pentafluoro-lambda6-sulfanyl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidin ... 2-(1,1-Difluoroethyl)-5-methyl-N-[4-(pentafluoro-λ6-sulfanyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7 ... Sulfur, (4-((2-(1,1-difluoroethyl)-5-methyl(1,2,4)triazolo(1,5-a)pyrimidin-7-yl)amino)phenyl)pentafluoro …
Matched Iupac: … 2-(1,1-difluoroethyl)-5-methyl-N-[4-(pentafluoro-lambda6-sulfanyl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidin …
Matched Description: … DSM265 has been used in trials studying the prevention and treatment of Malaria. …
Matched Iupac: … 2-(1,1-difluoroethyl)-5-methyl-N-[4-(pentafluoro-lambda6-sulfanyl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidin …
Matched Description: … DSM265 has been used in trials studying the prevention and treatment of Malaria. …
Ribavirin elaidate
Investigational
Matched Synonyms: … 1h-1,2,4-triazole-3-carboxamide, 1-(5-o-((9e)-1-oxo-9-octadecen-1-yl)-.beta.-d-ribofuranosyl)- …
Matched Iupac: … [(2R,3S,4R,5R)-5-(3-carbamoyl-1H-1,2,4-triazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl (9E)-octadec-9-enoate …
Matched Iupac: … [(2R,3S,4R,5R)-5-(3-carbamoyl-1H-1,2,4-triazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl (9E)-octadec-9-enoate …
MK-2206
Investigational
Matched Synonyms: … 1,2,4-Triazolo(3,4-f)(1,6)naphthyridin-3(2H)-one, 8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl- ... 8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one …
Matched Iupac: … 8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-2H,3H-[1,2,4]triazolo[3,4-f]1,6-naphthyridin-3-one …
Matched Iupac: … 8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-2H,3H-[1,2,4]triazolo[3,4-f]1,6-naphthyridin-3-one …
Displaying drugs 451 - 475 of 841 in total