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Displaying drugs 451 - 475 of 722 in total
Investigational
Matched Synonyms: … -neuraminic acid, n-acetyl-2-o-(7,26-dioxo-10,13,16,19,22-pentaoxa-6,25-diazapentaconta-35,37-diyn-1- …
Gibberella fujikuroi allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, fusarium moniliforme …
Novobiocin is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189) Novobiocin sodium, a salt form of novobiocin, was initially approved in September 1964...
Approved
Investigational
Vet approved
Withdrawn
Matched Synonyms: … N-{7-[(3-O-carbamoyl-6-deoxy-5-methyl-4-O-methyl-β-D-gulopyranosyl)oxy]-4-hydroxy-8-methyl-2-oxo-2H-chromen …
Matched Iupac: … -2H-chromen-7-yl}oxy)-3-methoxy-2,2-dimethyloxan-4-yl carbamate ... (3R,4S,5R,6R)-5-hydroxy-6-({4-hydroxy-3-[4-hydroxy-3-(3-methylbut-2-en-1-yl)benzamido]-8-methyl-2-oxo
Matched Description: … novobiocin, was initially approved in September 1964 and was indicated for the treatment of serious ... Novobiocin binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. ... In 2009, the FDA determined novobiocin sodium was withdrawn from sale for reasons of safety or effectiveness …
A nucleoside triphosphate analogue that is ATP in which one of the oxygens attached to 3-phosphate group is replaced by sulfur.
Experimental
Matched Synonyms: … Adenosine 5-O-(3-thiotriphophate) ... Adenosine 5'-O-(3-thiotriphosphate) …
Matched Iupac: … ](hydroxy)phosphoryl}oxy)phosphonothioic acid ... ({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy
Matched Description: … A nucleoside triphosphate analogue that is ATP in which one of the oxygens attached to 3-phosphate group …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Indicators and Reagents ... Nucleic Acids, Nucleotides, and Nucleosides …
Esculin is found in barley. Vitamin C2 is generally considered a bioflavanoid, related to vitamin P esculin is a glucoside that naturally occurs in the horse chestnut (Aesculus hippocastanum), California Buckeye (Aesculus californica) and in daphnin (the dark green resin of Daphne mezereum). Esculin belongs to the family of Glycosyl...
Approved
Matched Synonyms: … Esculetin 6-O-glucoside ... 6,7-Dihydroxycoumarin-6-O-glucoside ... 6-(beta-D-Glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one
Matched Iupac: … 7-hydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2H-chromen-2-one
Matched Description: … naturally occurs in the horse chestnut (Aesculus hippocastanum), California Buckeye (Aesculus californica) and ... , or Se- glycosidic bond. ... Esculin belongs to the family of Glycosyl Compounds. …
Matched Mixtures name: … Proctosone Ont
Mitotane is an adrenolytic isomer of the insecticide dichlorodiphenyldichloroethane (DDD) - itself a metabolite of dichlorodiphenyltrichloroethane (DDT) - that inhibits cells of the adrenal cortex and their production of hormones. It has been in use since 1959 for the treatment of inoperable adrenocortical carcinoma and is used off-label for the...
Approved
Matched Synonyms: … o,p'-DDD …
Matched Description: … metabolite of dichlorodiphenyltrichloroethane (DDT) - that inhibits cells of the adrenal cortex and their ... It has been in use since 1959 for the treatment of inoperable adrenocortical carcinoma[A263010] and is ... used off-label for the management of Cushing's syndrome. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
WP-1122 is a prodrug of 2-deoxy-D-glucose (2-DG). It was granted FDA orphan designation for the treatment of glioblastoma multiforme.
Investigational
Matched Synonyms: … 3,6-di-O-acetyl-2-deoxy-D-glucopyranose ... an acetic acid diester of 2-deoxy-D-glucose …
Matched Description: … WP-1122 is a prodrug of 2-deoxy-D-glucose (2-DG). ... It was granted FDA orphan designation for the treatment of glioblastoma multiforme.[L47361] …
Water (chemical formula: H2O) is a transparent fluid which forms the world's streams, lakes, oceans and rain, and is the major constituent of the fluids of organisms. As a chemical compound, a water molecule contains one oxygen and two hydrogen atoms that are connected by covalent bonds. Water is a...
Approved
Matched Description: … rain, and is the major constituent of the fluids of organisms. ... As a chemical compound, a water molecule contains one oxygen and two hydrogen atoms that are connected ... Water is a liquid at standard ambient temperature and pressure, but it often co-exists on Earth with …
Matched Mixtures name: … Oil ... Medium Cuts and Scratches ... Good Neighbor Pharmacy Emergency Preparedness and First Aid Contains 167 Pieces …
Matched Products: … Oil ... Roll-On ... Ori-power …
Bitolterol mesylate was used to treat bronchospasms in asthma and COPD. It is a beta-2-adrenergic receptor agonist. Bitolterol was withdrawn from the market by Elan Pharmaceuticals in 2001.
Withdrawn
Matched Synonyms: … 4-(2-(tert-butylamino)-1-hydroxyethyl)-o-phenylene di-p-toluate ... 4-[2-(tert-butylamino)-1-hydroxyethyl]-o-phenylene di-p-toluate …
Matched Description: … Bitolterol mesylate was used to treat bronchospasms in asthma and COPD. …
Gemcitabine elaidate has been used in trials studying the treatment of Solid Tumor, Lung Cancer, Non-small-cell Lung Cancer, and Metastatic Pancreatic Adenocarcinoma.
Investigational
Matched Synonyms: … 5'-O-(trans-9"-octadecenoyl)-1-beta-D-2'deoxy-2',2'-difluorocytidine ... 5'-O-(TRANS-9''-OCTADECENOYL)-1-.BETA.-D-2'DEOXY-2',2'-DIFLUOROCYTIDINE …
Matched Iupac: … [(2R,3R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4,4-difluoro-3-hydroxyoxolan-2-yl]methyl (9E) …
Matched Description: … Lung Cancer, and Metastatic Pancreatic Adenocarcinoma. ... Gemcitabine elaidate has been used in trials studying the treatment of Solid Tumor, Lung Cancer, Non-small-cell …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Methyl cellulose polymer consisting of numerous linked glucose molecules used as a stabiliser, thickener and emulsifier for foodstuffs and cosmetics. The Degree of Substitution (DS) of a given form of methyl cellulose is defined as the average number of substituted hydroxyl groups per glucose with a theoretical maximum of 3,...
Approved
Matched Description: … and emulsifier for foodstuffs and cosmetics. ... Like cellulose, it is not digestible, not toxic, and not allergenic ... The Degree of Substitution (DS) of a given form of methyl cellulose is defined as the average number …
Matched Categories: … Alimentary Tract and Metabolism ... Compounds used in a research, industrial, or household setting …
Matched Products: … Foster and Thrive Fiber Laxative 188 …
The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.
Approved
Experimental
Investigational
Matched Synonyms: … 5-O-phosphono-α-D-ribofuranosyl diphosphate …
Matched Name: … 5-O-phosphono-alpha-D-ribofuranosyl diphosphate …
Matched Iupac: … [({[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]oxy}(hydroxy)phosphoryl)oxy]phosphonic …
Matched Description: … The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides …
Experimental
Matched Name: … 4-O-methyl-beta-D-glucuronic acid …
Experimental
Matched Name: … 2,3-Di-O-Sulfo-Alpha-D-Glucopyranose …
Experimental
Matched Name: … Beta-1,2,3,4,6-Penta-O-Galloyl-D-Glucopyranose …
Experimental
Matched Name: … [4,6-O-(1-CARBOXYETHYLIDENE)-BETA-D-MANNOSE] …
Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. Compared to cisplatin the two amine groups are replaced by diamino cyclohexane (DACH) group to provide a greater antitumor effect. However, this leads to poorer water solubility, which was compensated by the addition of the chloride...
Approved
Investigational
Matched Synonyms: … L-OHP
Matched Description: … [A797] Oxaliplatin was approved by the FDA on January 9, 2004 and is currently marketed by Sanofi-Aventis ... [A260396] However, due to the structure of oxaliplatin, its adducts make the binding of mismatch repair ... leucovorin, known as the FOLFOX regimen, for the treatment of colorectal cancer. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … AL OXA ® SOLUCION CONCENTRADA PARA INFUSION ... O-PLAT 50 MG POLVO LIOFILIZADO PARA INYECC ION ... O-PLAT 100 MG POLVO LIOFILIZADO PARA INYECCION …
Tifcemalimab is under investigation in clinical trial NCT06095583 (Phase 3 Study of Toripalimab Alone or in Combination With Tifcemalimab as Consolidation Therapy in Patients With Limited-stage Small Cell Lung Cancer (LS-SCLC)).
Investigational
Matched Synonyms: … Immunoglobulin g4, anti-(human b and t lymphocyte attenuator (btla)) (human-mus musculus monoclonal js004 …
Matched Description: … Tifcemalimab is under investigation in clinical trial NCT06095583 (Phase 3 Study of Toripalimab Alone ... or in Combination With Tifcemalimab as Consolidation Therapy in Patients With Limited-stage Small Cell …
Investigational
Matched Synonyms: … (2R,4S)-4-amino-1-(5-O-(2-oxo-4-(4-pyridyl)-1,3,2-dioxaphosphorinan-2-yl)-beta-d-arabinofuranosyl)-2( ... 4-amino-1-(5-o-((2r, 4s)-2-oxido-4-(4-pyridinyl)-1, 3, 2-dioxaphosphorinan-2-yl)-.beta. ... 2(1h)-pyrimidinone, 4-amino-1-(5-o-((2r,4s)-2-oxido-4-(4-pyridinyl)-1,3,2-dioxaphosphorinan-2-yl)-.beta …
Matched Iupac: … -2-yl]oxy}methyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one ... 4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-({[(2S,4S)-2-oxo-4-(pyridin-4-yl)-1,3,2lambda5-dioxaphosphinan …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Cetirizine, also commonly known as Zyrtec, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and other symptoms , . One of the most common uses for this drug is for a condition called allergic...
Approved
Matched Description: … Allergic rhinitis is associated with multiple missed or unproductive days at work and school, problems ... , and up to 30%, according to self-reported nasal symptoms. ... One of the most common uses for this drug is for a condition called _allergic rhinitis_. …
Matched Mixtures name: … ZYRTEC D Allergy and Congestion ... Wal Zyr D Allergy and Congestion ... Cetirizine HCl and Pseudoephedrine HCl ER …
Matched Categories: … Cetirizine and isomer ... Decongestants and Antiallergics …
Matched Products: … INCIDAL - OD ... Our Family Childrens Cetirizine ... SIMTEC TABLET 10MG (OTC) …
Deacetyllanatoside C. A cardiotonic glycoside from the leaves of Digitalis lanata.
Approved
Matched Synonyms: … 3-[(O-β-D-glucopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl ... -(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-3β,5β,12β-card-20(22)-enolide ... dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl]oxy
Matched Iupac: … }oxan-2-yl]oxy}-6-methyloxan-2-yl]oxy}-6-methyloxan-2-yl]oxy}-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta ... [a]phenanthren-1-yl]-2,5-dihydrofuran-2-one ... {[(2S,4S,5S,6R)-4-hydroxy-6-methyl-5-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy
Matched Description: … A cardiotonic glycoside from the leaves of Digitalis lanata. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Dapiprazole (U.S. trade name Rev-Eyes) is an alpha blocker. It is found in ophthalmic solutions used to reverse mydriasis after an eye examination.
Approved
Matched Synonyms: … 5,6,7,8-Tetrahydro-3-(2-(4-(o-tolyl)-1-piperazinyl)ethyl)-s-triazolo(4,3-a)pyridine …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Benzethonium is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties. Its salt form, benzethonium chloride, is primarily used as a skin disinfectant at concentrations of 0.1-0.2 %, which are safe and effective concentrations for the compound specified by the U.S. Food and Drug Administration (FDA)....
Approved
Matched Description: … Its salt form, benzethonium chloride, is primarily used as a skin disinfectant at concentrations of 0.1 ... It is additionally found in cosmetics and toiletries such as mouthwashes and anti-itch ointments. ... Food and Drug Administration (FDA). …
Matched Mixtures name: … Oti-sol ... Gold Bond Pain and Itch ... Benzocaine and Benzethonium …
Matched Categories: … Antiseptics and Disinfectants …
Matched Products: … LYSOL Healthy Touch Cleansing Green Tea and Ginger ... Foaming Instant Hand Sanitizer with Aloe and Vitamin E ... Loesch Original Kleer-Plex Antimicrobial Face and Body Wash …
Lanolin is a yellow fat obtained from sheep's wool. It is used as an emollient, cosmetic, and pharmaceutic aid . The US federal code of regulations states that lanolin in the concentration range of 12-50% may be included in over the counter skin ointments . Lanolin is the purified, secreted...
Approved
Matched Synonyms: … Wool oil ... Lanolin oil
Matched Description: … Lanolin is used in the protection, treatment, and cosmetic enhancement of human skin. ... It is used as an emollient, cosmetic, and pharmaceutic aid [L2580]. ... Lanolin primarily consists of long-chain waxy esters, or sterol esters, that lack glycerides. …
Matched Mixtures name: … Optilube Ont ... Therapeutic Bath Oil ... A and D Diaper Rash and Skin Protectant …
Matched Categories: … Basic Ointments and Protectants ... Compounds used in a research, industrial, or household setting …
Matched Products: … Soothe and Cool Free Medseptic Skin Protectant …
Experimental
Matched Synonyms: … 1,6-di-O-phosphono-β-D-fructofuranose …
Displaying drugs 451 - 475 of 722 in total