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Displaying drugs 451 - 475 of 704 in total
Teneligliptin has been investigated for the treatment of Type 2 Diabetes Mellitus.
Investigational
Matched Categories: … Sulfur Compounds ... Alimentary Tract and Metabolism ... metformin and teneligliptin …
Fasitibant is under investigation in clinical trial NCT02205814 (Fasitibant Intra-articular Injection in Patients With Symptomatic Osteoarthritis of the Knee).
Investigational
Matched Categories: … Sulfur Compounds ... Amino Acids, Peptides, and Proteins …
Experimental
Matched Iupac: … (2S)-2-amino-5-(carbamothioylamino)pentanoic acid
Matched Categories: … Sulfur Compounds ... Amino Acids, Peptides, and Proteins …
Vidupiprant has been used in trials studying the treatment and basic science of Asthma.
Investigational
Matched Iupac: … tert-butylcarbamoyl)-2-(2-chloro-4-cyclopropylbenzenesulfonamido)phenoxy]-5-chloro-2-fluorophenyl}acetic acid
Matched Description: … Vidupiprant has been used in trials studying the treatment and basic science of Asthma. …
Matched Categories: … Sulfur Compounds …
Glisoxepide is one of the sulphonamide-derived oral antidiabetic drugs. It inhibits the uptake of bile acids into isolated rat hepatocytes. However it inhibits taurocholate uptake only in the absence of sodium ions. Glisoxepide uptake could be further inhibited by blockers of the hepatocellular monocarboxylate transporter, by the loop diuretic bumetanide,...
Investigational
Matched Description: … transporter, by the loop diuretic bumetanide, by 4,4'-diisothiocyano-2,2'-stilbenedisulfonate (DIDS) and ... are consistent with the transport of glisoxepide via the transport system for the unconjugated bile acid
Matched Categories: … Sulfur Compounds ... Alimentary Tract and Metabolism …
KD3010 is a small molecule peroxisome proliferator-activator receptor delta (PPAR Delta) agonist for the treatment of metabolic disorders, including obesity.
Investigational
Matched Iupac: … ]sulfonyl}-2,3-dihydro-1H-indene-2-carboxylic acid ... 4-methylbenzene-1-sulfonic acid; 4-{[(2R,6S)-2,6-dimethyl-4-[4-(trifluoromethoxy)phenyl]piperazin-1-yl …
Matched Categories: … Sulfur Compounds …
LCL161 has been used in trials studying the treatment of Leukemia, Neoplasms, Solid Tumors, Breast Cancer, and Ovarian Cancer, among others.
Investigational
Matched Description: … has been used in trials studying the treatment of Leukemia, Neoplasms, Solid Tumors, Breast Cancer, and
Matched Categories: … Sulfur Compounds …
Alethine is studied in the treatment of cancer. It belongs to a family of chemicals called disulfides. It is a low molecular weight disulfide that has been shown to exhibit in vivo antitumor activity in murine myeloma and melanoma models.
Investigational
Matched Description: … molecular weight disulfide that has been shown to exhibit in vivo antitumor activity in murine myeloma and
Matched Categories: … Sulfur Compounds …
LSZ-102 is under investigation in clinical trial NCT02734615 (Phase I/Ib Trial of LSZ102 Single Agent or LSZ102 + LEE011 or LSZ102 + BYL719 in ER+ Breast Cancers).
Investigational
Matched Iupac: … 4-({2-[2-(1,1-difluoroethyl)-4-fluorophenyl]-6-hydroxy-1-benzothiophen-3-yl}oxy)phenyl]prop-2-enoic acid
Matched Categories: … Sulfur Compounds …
Sivelestat has been used in trials studying the treatment of Acute Lung Injury and Respiratory Distress Syndrome, Adult.
Investigational
Matched Iupac: … 2-[(2-{4-[(2,2-dimethylpropanoyl)oxy]benzenesulfonamido}phenyl)formamido]acetic acid
Matched Description: … Sivelestat has been used in trials studying the treatment of Acute Lung Injury and Respiratory Distress …
Matched Categories: … Sulfur Compounds ... Amino Acids, Peptides, and Proteins …
Aleglitazar is an investigational drug from the company Hoffmann–La Roche and is currently in a phase III clinical trial called ALECARDIO. It is being investigated for use in patients with type II diabetes to reduce their risks of cardiovascular mortality and morbidity. Aleglitazar is an agonist at the peroxisome proliferator-activated...
Investigational
Matched Iupac: … (2S)-2-methoxy-3-{4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]-1-benzothiophen-7-yl}propanoic acid
Matched Description: … Aleglitazar is an investigational drug from the company Hoffmann–La Roche and is currently in a phase ... glucose levels in a synergistic manner while also having limited side effects and toxicity. ... trial called SYNCHRONY, with type II diabetic patients, aleglitazar was able to control both lipid and
Matched Categories: … Sulfur Compounds …
5'-S-(3-Amino-3-carboxypropyl)-5'-thioadenosine. Formed from S-adenosylmethionine after transmethylation reactions.
Experimental
Matched Iupac: … amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}sulfanyl)butanoic acid
Matched Categories: … Amino Acids, Sulfur ... Sulfur Compounds ... Amino Acids, Peptides, and Proteins ... Nucleic Acids, Nucleotides, and Nucleosides …
Letosteine is a mucolytic used in the treatment of chronic bronchopneumopathies and related conditions.
Experimental
Matched Iupac: … 2-{2-[(2-ethoxy-2-oxoethyl)sulfanyl]ethyl}-1,3-thiazolidine-4-carboxylic acid
Matched Description: … Letosteine is a mucolytic used in the treatment of chronic bronchopneumopathies and related conditions …
Matched Categories: … Sulfur Compounds ... Cough and Cold Preparations …
LGD-6972 is under investigation in clinical trial NCT01919684 (Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LGD-6972 in Healthy Subjects and Subjects With Type 2 Diabetes Mellitus).
Investigational
Matched Iupac: … -yl}-2-({2',4',6'-trimethyl-[1,1'-biphenyl]-4-yl}carbamoyl)ethyl]phenyl}formamido)ethane-1-sulfonic acid
Matched Description: … Pharmacodynamics of LGD-6972 in Healthy Subjects and Subjects With Type 2 Diabetes Mellitus). ... investigation in clinical trial NCT01919684 (Study to Evaluate Safety, Tolerability, Pharmacokinetics and
Matched Categories: … Sulfur Acids ... Sulfur Compounds …
Irosustat has been investigated for the treatment of Metastatic Breast Cancer and Locally Advanced Breast Cancer.
Investigational
Matched Description: … Irosustat has been investigated for the treatment of Metastatic Breast Cancer and Locally Advanced Breast …
Matched Categories: … Sulfur Acids ... Sulfur Compounds …
Ertiprotafib belongs to a novel class of insulin sensitizers developed for treatment of type 2 diabetes. In insulin-resistant rodent models, ertiprotafib and a close analog lowered both fasting blood glucose and insulin levels and improved glycemic excursion during an oral glucose tolerance test.
Investigational
Matched Iupac: … (2R)-2-(4-{9-bromo-2,3-dimethylnaphtho[2,3-b]thiophen-4-yl}-2,6-dimethylphenoxy)-3-phenylpropanoic acid
Matched Description: … and insulin levels and improved glycemic excursion during an oral glucose tolerance test. ... In insulin-resistant rodent models, ertiprotafib and a close analog lowered both fasting blood glucose …
Matched Categories: … Sulfur Compounds …
Glucoraphanin is under investigation in clinical trial NCT01879878 (Pilot Study Evaluating Broccoli Sprouts in Advanced Pancreatic Cancer [POUDER Trial]).
Investigational
Matched Iupac: … 2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]sulfanyl}pentylidene)amino]oxy}sulfonic acid
Matched Categories: … Sulfur Compounds …
Epalrestat is under investigation in clinical trial NCT03244358 (Evaluation of Epalrestat in Metastatic Triple-negative Breast Cancer).
Investigational
Matched Iupac: … 5Z)-5-[(2E)-2-methyl-3-phenylprop-2-en-1-ylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid
Matched Categories: … Sulfur Compounds …
Racecadotril has been investigated for the basic science and treatment of Diarrhea, Acute Diarrhea, and Acute Gastroenteritis.
Investigational
Matched Description: … Racecadotril has been investigated for the basic science and treatment of Diarrhea, Acute Diarrhea, and
Matched Categories: … Amino Acids, Sulfur ... Sulfur Compounds ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Esaxerenone is under investigation in clinical trial NCT02722265 (Long-term Study of CS-3150 as Monotherapy or in Combination With Other Antihypertensive Drug in Japanese Patients With Essential Hypertension).
Investigational
Matched Categories: … Sulfur Compounds …
Experimental
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Sulfur ... Sulfur Compounds …
Rigosertib has been used in trials studying the treatment and basic science of MDS, RAEB, Cancer, Hepatoma, and Neoplasms, among others.
Investigational
Matched Iupac: … 2-[(2-methoxy-5-{[(E)-2-(2,4,6-trimethoxyphenyl)ethenesulfonyl]methyl}phenyl)amino]acetic acid
Matched Description: … , and Neoplasms, among others. ... Rigosertib has been used in trials studying the treatment and basic science of MDS, RAEB, Cancer, Hepatoma …
Matched Categories: … Sulfur Compounds ... Amino Acids, Peptides, and Proteins …
Radalbuvir has been used in trials studying the treatment of Chronic Hepatitis C, Chronic HCV Infection, and Chronic Hepatitis C Infection.
Investigational
Matched Iupac: … -{[(3S)-oxolan-3-yloxy]methyl}cyclohexyl](1R)-4-methylcyclohex-3-ene-1-amido}thiophene-2-carboxylic acid
Matched Description: … Radalbuvir has been used in trials studying the treatment of Chronic Hepatitis C, Chronic HCV Infection, and
Matched Categories: … Sulfur Compounds …
T900607 has been used in trials studying the treatment of Liver Cancer and Gastric Cancer.
Investigational
Matched Description: … T900607 has been used in trials studying the treatment of Liver Cancer and Gastric Cancer. …
Matched Categories: … Sulfur Compounds …
Experimental
Matched Categories: … Preparations Containing Sulfur
Displaying drugs 451 - 475 of 704 in total