Displaying drugs 451 - 475 of 15379 in total
Adefovir dipivoxil
Adefovir dipivoxil, previously called bis-POM PMEA, with trade names Preveon and Hepsera, is an orally-administered acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI) used for treatment of hepatitis B. It is ineffective against HIV-1. Adefovir dipivoxil is the diester prodrug of adefovir.
Approved
Investigational
Matched Description: … Adefovir dipivoxil, previously called bis-POM PMEA, with trade names Preveon and Hepsera, is an orally-administered …
Matched Categories: … Nucleosides and Nucleotides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …
Matched Categories: … Nucleosides and Nucleotides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …
Taurocholic acid
The product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as a cholagogue and cholerectic.
Approved
Experimental
Matched Description: … It is used as a cholagogue and cholerectic. ... It acts as a detergent to solubilize fats for absorption and is itself absorbed. …
Matched Categories: … Bile Acids and Salts ... Compounds used in a research, industrial, or household setting ... Cholagogues and Choleretics …
Matched Categories: … Bile Acids and Salts ... Compounds used in a research, industrial, or household setting ... Cholagogues and Choleretics …
Iohexol
Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
Approved
Matched Description: … Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography ... , nephroangiography, arteriography, and other radiographic procedures. ... Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Berotralstat
Berotralstat is a selective inhibitor of plasma kallikrein used in the prophylaxis of attacks of hereditary angioedema (HAE). It works by blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated with attacks of HAE. Berotralstat is strictly used to...
Approved
Matched Description: … adults and pediatric patients 12 years and older. ... Berotralstat is a selective inhibitor of plasma kallikrein used in the prophylaxis of attacks of hereditary ... [L26661] It works by blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the …
Matched Categories: … Blood and Blood Forming Organs ... Drugs Used in Hereditary Angioedema …
Matched Categories: … Blood and Blood Forming Organs ... Drugs Used in Hereditary Angioedema …
Linagliptin
Linagliptin is a DPP-4 inhibitor developed by Boehringer Ingelheim for the treatment of type II diabetes . Linagliptin differs from other DPP-4 inhibitors in that it has a non-linear pharmacokinetic profile, is not primarily eliminated by the renal system, and obeys concentration dependant protein binding . Linagliptin was approved by...
Approved
Matched Description: … Linagliptin differs from other DPP-4 inhibitors in that it has a non-linear pharmacokinetic profile, ... is not primarily eliminated by the renal system, and obeys concentration dependant protein binding[A37050 …
Matched Categories: … Drugs Used in Diabetes ... Alimentary Tract and Metabolism ... metformin and linagliptin ... linagliptin and empagliflozin ... metformin, linagliptin and empagliflozin …
Matched Categories: … Drugs Used in Diabetes ... Alimentary Tract and Metabolism ... metformin and linagliptin ... linagliptin and empagliflozin ... metformin, linagliptin and empagliflozin …
Bordetella pertussis toxoid antigen (glutaraldehyde inactivated)
Approved
Investigational
Matched Mixtures name: … FILAMENTOUS HEMAGGLUTININ ANTIGEN (FORMALDEHYDE INACTIVATED), BORDETELLA PERTUSSIS PERTACTIN ANTIGEN, and …
Vibrio cholerae Ogawa 50 classical biotype, formalin inactivated
Approved
Matched Mixtures name: … DUKORAL VACCINE AGAINST CHOLERA AND ETEC-DIARRHOEA …
Influenza A virus A/Kansas/14/2017 (H3N2) live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …
Iothalamic acid
Iothalamic acid is an iodine containing organic anion used as a diagnostic contrast agent.
Approved
Matched Categories: … Compounds used in a research, industrial, or household setting …
Cefixime
Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Investigational
Matched Description: … [A263031] Cefixime was first approved in the United States in 1986.[L49293] ... , and meningitis. ... [T894, T322] Additionally, third-generation cephalosporins have been shown to have more stability in …
Matched Categories: … cefixime and ornidazole ... cefixime and azithromycin …
Matched Categories: … cefixime and ornidazole ... cefixime and azithromycin …
Dimethyl sulfoxide
A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during cryopreservation. Dimethyl sulfoxide shows a range of pharmacological activity including...
Approved
Vet approved
Matched Description: … Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Genito Urinary System and Sex Hormones ... Topical Products for Joint and Muscular Pain …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Genito Urinary System and Sex Hormones ... Topical Products for Joint and Muscular Pain …
Tolbutamide
Tolbutamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It is structurally similar to acetohexamide, chlorpropamide and tolazamide and belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin...
Approved
Investigational
Matched Description: … Tolbutamide and its metabolites are excreted in urine (75-85%) and feces. ... The risk of hypoglycemia is increased in elderly, debilitated and malnourished individuals. ... Medications in this class differ in their dose, rate of absorption, duration of action, route of elimination …
Matched Categories: … Drugs Used in Diabetes ... Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Categories: … Drugs Used in Diabetes ... Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Anthrax vaccine
Anthrax vaccine is a vaccine used for the pre- or post-exposure prophylaxis of disease in those at high risk of, suspected or confirmed exposure to Bacillus anthracis. It is subcutaneously or intramuscularly administered. It is derived from cell-free filtrates of microaerophilic cultures of an avirulent, nonencapsulated strain of Bacillus anthracis...
Approved
Matched Description: … [L47561]
There are currently 2 anthrax vaccines approved by the FDA: BioThrax in August 15, 2016 and ... CYFENDUS in July 20, 2023. ... [L47566, L47561] These vaccines are currently stored in the Strategic National Stockpile in preparation …
Ebola Zaire vaccine (live, attenuated)
Ebola virus vaccine is a vaccine used to prevent Ebola virus disease caused by Zaire ebolavirus in adults, prevent outbreaks, and reduce the extent of the virus spreading in case of outbreaks. Ebola virus disease, formerly known as Ebola hemorrhagic fever, is a rare but severe and often deadly disease....
Approved
Matched Description: … total deaths during this time in Guinea, Liberia, and Sierra Leone. ... adults, prevent outbreaks, and reduce the extent of the virus spreading in case of outbreaks. ... [A188994] Between 2014 and 2016, Ebola outbreaks occurred in West Africa, leading to more than 11,310 …
Riluzole
A glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong the survival of patients with amyotrophic lateral sclerosis. Riluzole is marketed as Rilutek by Sanofi.
Approved
Investigational
Matched Description: … A glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Emtricitabine
Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) indicated for the treatment of HIV infection in adults or combined with tenofovir alafenamide for the prevention of HIV-1 infection in high risk adolescents and adults. Emtricitabine is a cytidine analogue. The drug works by inhibiting HIV reverse transcriptase, preventing transcription of...
Approved
Investigational
Matched Description: … risk adolescents and adults. ... is a nucleoside reverse transcriptase inhibitor (NRTI) indicated for the treatment of HIV infection in ... adults[L9019] or combined with [tenofovir alafenamide] for the prevention of HIV-1 infection in high …
Matched Mixtures name: … Emtricitabine and Tenofovir Disoproxil Fumarate ... Emtricitabine and Tenofovir Disoproxil Fumarate ... Emtricitabine and Tenofovir Disoproxil Fumarate …
Matched Categories: … Antivirals used in combination for the treatment of HIV infections ... tenofovir disoproxil and emtricitabine ... emtricitabine and tenofovir alafenamide ... Nucleic Acids, Nucleotides, and Nucleosides ... emtricitabine, tenofovir disoproxil and efavirenz …
Matched Mixtures name: … Emtricitabine and Tenofovir Disoproxil Fumarate ... Emtricitabine and Tenofovir Disoproxil Fumarate ... Emtricitabine and Tenofovir Disoproxil Fumarate …
Matched Categories: … Antivirals used in combination for the treatment of HIV infections ... tenofovir disoproxil and emtricitabine ... emtricitabine and tenofovir alafenamide ... Nucleic Acids, Nucleotides, and Nucleosides ... emtricitabine, tenofovir disoproxil and efavirenz …
Levetiracetam
Levetiracetam is a drug within the pyrrolidine class that is used to treat various types of seizures stemming from epileptic disorders. It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated to other anti-epileptic drugs (AEDs).[L8606,L8600,L8615] Levetiracetam possesses a wide therapeutic index[L8615,A185918]...
Approved
Matched Description: … It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated ... a propensity for involvement in drug interactions. ... [L8606,L8600,L8615] Levetiracetam possesses a wide therapeutic index[L8615,A185918] and little-to-no …
Matched Products: … Levetiracetam in Sodium Chloride …
Matched Products: … Levetiracetam in Sodium Chloride …
Influenza B virus B/Maryland/15/2016 recombinant hemagglutinin antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …
Amaranthus hybridus pollen
Amaranthus hybridus pollen allergenic extract is used in allergenic testing.
Approved
Matched Description: … Amaranthus hybridus pollen allergenic extract is used in allergenic testing. …
Dermatophagoides pteronyssinus
Dermatophagoides pteronyssinus extracts are sterile solutions used for intradermal testing or subcutaneous immunotherapy. This combination is approved for as a year-round, once-a-day tablet that's dissolved under the tongue as a treatment for dust mite allergies.
Approved
Matched Mixtures name: … Standardized Mite Mix Dermatophagoides farinae and Dermatophagoides pteronyssinus ... Standardized Mite Mix Dermatophagoides farinae and Dermatophagoides pteronyssinus ... Standardized Mite Mix, Dermatophagoides pteronyssinus and Dermatophagoides farinae, 10000 AU per mL …
Thrombin
Also known as coagulation factor II, thrombin is a serine protease that plays a physiological role in regulating hemostasis and maintaining blood coagulation. Once converted from prothrombin, thrombin converts fibrinogen to fibrin, which, in combination with platelets from the blood, forms a clot.
Medical thrombin is a protein substance produced...
Approved
Investigational
Matched Description: … bovine origin is activated by tissue thromboplastin in the presence of calcium chloride. ... regulating hemostasis and maintaining blood coagulation. ... Patients who are know or suspected to have antibodies to bovine thrombin and/or bovine factor V should …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Thiopental
A barbiturate that is administered intravenously for the induction of general anesthesia or for the production of complete anesthesia of short duration. It is also used for hypnosis and for the control of convulsive states. It has been used in neurosurgical patients to reduce increased intracranial pressure. It does not...
Approved
Vet approved
Matched Description: … It has been used in neurosurgical patients to reduce increased intracranial pressure. ... It is also used for hypnosis and for the control of convulsive states. ... Small doses have been shown to be anti-analgesic and lower the pain threshold. …
Matched Categories: … Hypnotics and Sedatives …
Matched Categories: … Hypnotics and Sedatives …
Isoprenaline
Isoprenaline is a non-selective beta adrenergic receptor agonist indicated to treat heart block, Adams-Stokes attacks, bronchospasm in anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and cardiogenic shock.[A15638,L33160]
Isoprenaline research in the 1940s found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising...
Approved
Investigational
Matched Description: … beta adrenergic receptor agonist indicated to treat heart block, Adams-Stokes attacks, bronchospasm in ... [A15638,L33160]
Isoprenaline research in the 1940s found that this isopropyl analog of epinephrine ... anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Adrenergic and Dopaminergic Agents ... isoprenaline and other drugs for obstructive airway diseases …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Adrenergic and Dopaminergic Agents ... isoprenaline and other drugs for obstructive airway diseases …
Displaying drugs 451 - 475 of 15379 in total