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Displaying drugs 4776 - 4800 of 10515 in total

Alvespimycin

Alvespimycin is a derivative of geldanamycin and heat shock protein (HSP) 90 inhibitor. It has been used in trials studying the treatment of solid tumor in various cancer as an antitumor agent. In comparison to the first HSP90 inhibitor tanespimycin, it exhibits some pharmacologically desirable properties such as reduced metabolic...
Investigational
Matched Description: … Alvespimycin is a derivative of geldanamycin and heat shock protein (HSP) 90 inhibitor. ... It has been used in trials studying the treatment of solid tumor in various cancer as an antitumor agent …

DPDPE

A heterodetic cyclic peptide that is a cyclic enkephalin analogue, having D-penicillaminyl residues located at positions 2 and 5, which form the heterocycle via a disulfide bond.
Experimental
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Menatetrenone

Menatetrenone has been used in trials studying the treatment of Diabetes, Osteoporosis, Prediabetic State, and Hepatocellular Carcinoma.
Investigational
Matched Description: … Menatetrenone has been used in trials studying the treatment of Diabetes, Osteoporosis, Prediabetic State …
Matched Categories: … Drugs for Treatment of Bone Diseases …

Promestriene

Promestriene (3-propyl ethyl, 17B-methyl estradiol) has been used in trials studying the prevention of Hypospadias. It is a synthetic estrogen analog, which is used in topical estrogen therapy. Promestriene’s potential for treating vaginal atrophy symptoms associated with aromatase inhibitor treatment would be precluded if its minimal absorption leads to estrogen-like...
Investigational
Matched Description: … Promestriene has been studied in phase IV of the clinical trial on improvement of hormonal cytology, ... In addition, promestriene was in phase IV of the clinical trial to study its treatment of patients with ... Promestriene (3-propyl ethyl, 17B-methyl estradiol) has been used in trials studying the prevention of …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Ioglycamic acid

Experimental
Matched Categories: … Diagnostic Uses of Chemicals …

Iocarmic acid

Experimental
Matched Categories: … Diagnostic Uses of Chemicals …

Umifenovir

Umifenovir is an indole-based, hydrophobic, dual-acting direct antiviral/host-targeting agent used for the treatment and prophylaxis of influenza and other respiratory infections. It has been in use in Russia for approximately 25 years and in China since 2006. Its invention is credited to a collaboration between Russian scientists from several research...
Investigational
Matched Description: … hydrophobic, dual-acting direct antiviral/host-targeting agent used for the treatment and prophylaxis of ... collaboration between Russian scientists from several research institutes 40-50 years ago, and reports of ... effects through multiple pathways has resulted in considerable investigation into its use for a variety of …

Tandospirone

Tandospirone has been used in trials studying the treatment of Schizophrenia.
Investigational
Matched Description: … Tandospirone has been used in trials studying the treatment of Schizophrenia. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Garlic oil

Experimental
Matched Categories: … Metabolic Side Effects of Drugs and Substances …

Vecabrutinib

Vecabrutinib is under investigation in clinical trial NCT03037645 (Safety, PK, PD, and Antitumor Activity of Vecabrutinib (SNS-062) in B Lymphoid Cancers).
Investigational
Matched Iupac: … (3R,3'R,4'S)-1'-(6-amino-5-fluoropyrimidin-4-yl)-3-{[3-chloro-5-(trifluoromethyl)phenyl]amino}-2-oxo- …
Matched Description: … Vecabrutinib is under investigation in clinical trial NCT03037645 (Safety, PK, PD, and Antitumor Activity of …

S65487

S65487 a potent and selective BCL-2 inhibitor, and a prodrug of S55746.
Investigational
Matched Description: … S65487 a potent and selective BCL-2 inhibitor, and a prodrug of S55746. …

BMS-986158

BMS-986158 is under investigation in clinical trial NCT02419417 (Study of BMS-986158 in Subjects With Select Advanced Cancers).
Investigational
Matched Iupac: … 2-[3-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-5-[(S)-(oxan-4-yl)(phenyl)methyl]-5H-pyrido[3,2-b]indol-7-yl …
Matched Description: … BMS-986158 is under investigation in clinical trial NCT02419417 (Study of BMS-986158 in Subjects With …

S64315

S64315 (MIK665) is an inhibitor of induced myeloid leukemia cell differentiation protein Myeloid cell leukemia 1 (Mcl-1).
Investigational
Matched Description: … S64315 (MIK665) is an inhibitor of induced myeloid leukemia cell differentiation protein Myeloid cell …

AV-412

Investigational

Bevacizumab zirconium Zr-89

Bevacizumab zirconium Zr-89 is under investigation in clinical trial NCT01338090 (89Zr-bevacizumab PET Imaging in Patients With Neuroendocrine Tumors).
Investigational
Matched Categories: … Diagnostic Uses of Chemicals …

Motexafin gadolinium

Motexafin gadolinium is studied in the treatment of cancer by Pharmacyclics. It may make tumor cells more sensitive to radiation therapy, improve tumor images using magnetic resonance imaging (MRI), and kill cancer cells. It belongs to the family of drugs called metalloporphyrin complexes. Also called gadolinium texaphyrin.
Investigational
Matched Description: … Motexafin gadolinium is studied in the treatment of cancer by Pharmacyclics. ... It belongs to the family of drugs called metalloporphyrin complexes. …
Matched Categories: … Diagnostic Uses of Chemicals …

Dimetacrine

Dimetacrine is also known as dimethacrine or acripamine. It is marketed under the names Istonil, Istonyl, Linostil, and Miroistonil. Dimetacrine is a tricyclic antidepressant (TCA) with imipramine-like effects used in Europe for the treatment of depression. Dimetacrine is no longer used in Japan.
Experimental
Withdrawn
Matched Description: … Dimetacrine is a tricyclic antidepressant (TCA) with imipramine-like effects used in Europe for the treatment of …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Lofepramine

Experimental
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Cefovecin

Cefovecin is a cephalosporin antibiotic used for the treatment of skin infections in cats and dogs. It is the first single-dose injectable antibiotic for dogs and cats that assures owner compliance with dosing for the animal. It is used for the treatment of skin infections caused by Pasturella multocida in...
Experimental
Vet approved
Matched Description: … intermedius/S. canis in dogs. ... The presence of low concentrations of antibiotics is related to the development of microbial resistance ... Cefovecin is a cephalosporin antibiotic used for the treatment of skin infections in cats and dogs. …

Dimethyltryptamine

An N-methylated indoleamine derivative, a serotonergic hallucinogen found in several plants, especially Prestonia amazonica (Apocynaceae) and in mammalian brain, blood, and urine. It apparently acts as an agonist at some types of serotonin receptors and an antagonist at others.
Experimental
Illicit
Matched Description: … It apparently acts as an agonist at some types of serotonin receptors and an antagonist at others. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Pipamperone

Pipamperone is a typical antipsychotic of the butyrophenone family used in the treatment of schizophrenia. It was developed by Janssen Pharmaceutica in 1961 and started its first round of clinical trials in 1963 [L1514, L1518]. In an effort to improve haloperidol's pharmacological effects, Janssen discovered that pipamperone, an agent whose...
Investigational
Matched Description: … In an effort to improve [haloperidol]'s pharmacological effects, Janssen discovered that pipamperone, ... Pipamperone is a typical antipsychotic of the _butyrophenone_ family used in the treatment of schizophrenia ... It was developed by Janssen Pharmaceutica in 1961 and started its first round of clinical trials in 1963 …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Acetrizoic acid

Acetrizoic acid presents the molecular formula of 3-acetamidol-2,4,6-triiodobenzoic acid and it is the first monomeric ionic compound used as an X-ray contrast agent. It was first synthesized by Wallingford in 1953 and it was filled in the FDA by the Johnson & Johnson subsidiary, Cilag Chemie AG, on February 8th,...
Withdrawn
Matched Description: … Acetrizoic acid presents the molecular formula of 3-acetamidol-2,4,6-triiodobenzoic acid[L1702] and it ... [L1704] Acetrizoic acid presents, in the FDA records, a category of drug substance with an inactive status …
Matched Categories: … Diagnostic Uses of Chemicals …

Moxestrol

Experimental
Matched Categories: … Sex Hormones and Modulators of the Genital System …

2-[4-(Hydroxy-Methoxy-Methyl)-Benzyl]-7-(4-Hydroxymethyl-Benzyl)-1,1-Dioxo-3,6-Bis-Phenoxymethyl-1lambda6-[1,2,7]Thiadiazepane-4,5-Diol

Experimental
Matched Iupac: … (3R,4S,5S,6R)-4,5-dihydroxy-2-({4-[(S)-hydroxy(methoxy)methyl]phenyl}methyl)-7-{[4-(hydroxymethyl)phenyl …

Marizomib

Marizomib has been used in trials studying the treatment of Cancer, Melanoma, Lymphoma, Glioblastoma, and Malignant Glioma, among others.
Investigational
Matched Iupac: … (1R,4R,5S)-4-(2-chloroethyl)-1-[(S)-[(1S)-cyclohex-2-en-1-yl](hydroxy)methyl]-5-methyl-6-oxa-2-azabicyclo …
Matched Description: … Marizomib has been used in trials studying the treatment of Cancer, Melanoma, Lymphoma, Glioblastoma, …
Displaying drugs 4776 - 4800 of 10515 in total