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Displaying drugs 4826 - 4850 of 10656 in total

Alaproclate

Alaproclate was developed as one of the first selective serotonin reuptake inhibitor (SSRI) antidepressants by Astra AB (now AstraZeneca) in the 1970s. Development was discontinued due to concerns over hepatotoxicity observed in animal studies. Alaproclate has also been found to act as a non-competitive NMDA receptor antagonist although without discriminative...
Experimental
Matched Description: … Alaproclate was developed as one of the first selective serotonin reuptake inhibitor (SSRI) antidepressants …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Fostroxacitabine bralpamide

Investigational
Matched Iupac: … (2S)-pentan-2-yl (2S)-2-{[(S)-{[(2S,4S)-4-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-1,3-dioxolan-2-yl …

ADU-S100

ADU-S100 (MIW815) is a synthetic cyclic dinucleotide (CDN) agonist (activator) of Stimulator of Interferon Genes (STING), a receptor crucial to activate the innate (endogenous) immune system. ADU-S100 (MIW815) activates all known human and mouse STINGs, and effectively induces the expression of cytokines and chemokines, leading to a robust and durable...
Investigational
Matched Description: … ADU-S100 (MIW815) is a synthetic cyclic dinucleotide (CDN) agonist (activator) of Stimulator of Interferon ... ADU-S100 (MIW815) activates all known human and mouse STINGs, and effectively induces the expression of …

Cenicriviroc

Cenicriviroc has been used in trials studying the treatment of HIV-infection/AIDS, AIDS Dementia Complex, Nonalcoholic Steatohepatitis, Human Immunodeficiency Virus, and HIV-1-Associated Cognitive Motor Complex.
Investigational
Matched Iupac: … (5E)-8-[4-(2-butoxyethoxy)phenyl]-1-(2-methylpropyl)-N-{4-[(S)-(1-propyl-1H-imidazol-5-yl)methanesulfinyl …
Matched Description: … Cenicriviroc has been used in trials studying the treatment of HIV-infection/AIDS, AIDS Dementia Complex …

ONO-2952

ONO-2952 is under investigation in clinical trial NCT01887002 (Study to Evaluate the Effects of ONO-2952 on Pain Perception Produced by Rectal Distention in Female Subjects With Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D)).
Investigational
Matched Iupac: … 1-[(1'S)-1'-(4-chloro-2-methoxyphenyl)-5'-fluoro-1',2',3',9'-tetrahydrospiro[cyclopropane-1,4'-pyrido …
Matched Description: … ONO-2952 is under investigation in clinical trial NCT01887002 (Study to Evaluate the Effects of ONO-2952 …

MMDA

MMDA, or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant and psychedelic properties. It also acts as an entheogen and an entactogen. MMDA bears resemblance to the psychopharmacologically active essential oils elemicin and myristicin found in nutmeg. The effects of MMDA includes feelings of euphoria and warmth,...
Experimental
Illicit
Matched Description: … The effects of MMDA includes feelings of euphoria and warmth, as well as realistic closed-eye visuals ... MMDA, or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Rifalazil

Rifalazil is a derivative of the antibiotic rifamycin. It is being investigated by ActivBiotics for the treatment of various bacterial infections.
Investigational
Matched Description: … Rifalazil is a derivative of the antibiotic rifamycin. ... It is being investigated by ActivBiotics for the treatment of various bacterial infections. …
Matched Categories: … Drugs for Treatment of Tuberculosis …

Cysteine-Methylene-Carbamoyl-1,10-Phenanthroline

Experimental

PARA-NITROPHENYL 1-THIO-BETA-D-GLUCOPYRANOSIDE

Experimental

Pirlimycin

Pirlimycin hydrochloride is an antibiotic belonging to the lincosamide class. Often marketed as Pirsue, this drug is used to treat mastitis in cattle.
Vet approved

(R)-carnitinyl-CoA betaine

Experimental

Chamaecyparis obtusa whole

Experimental
Matched Mixtures name: … S GVD Phytoncide ... S GVD Phytoncide …

Imipramine oxide

Experimental
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Etynodiol

Etynodiol (INN), or ethynodiol (BAN) is a steroidal progestin related to norethisterone which was never marketed. While etynodiol is sometimes used as a synonym for etynodiol diacetate, it usually refers to etynodiol diacetate (see DB00823), not etynodiol.
Experimental
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Bilh 434

Experimental
Matched Iupac: … (2R,3'R,4'S,5'R)-5'-(3,4-dichlorophenyl)-6-methyl-1,3-dioxo-4'-{[4-(1,2,3-thiadiazol-4-yl)phenyl]carbamoyl …

Adafosbuvir

Adafosbuvir is under investigation in clinical trial NCT02894905 (A Study to Evaluate the Effect of Renal Impairment on the Pharmacokinetics of AL-335).
Investigational
Matched Iupac: … propan-2-yl (2S)-2-{[(S)-{[(2S,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-2-fluoro-3,4- …
Matched Description: … Impairment on the Pharmacokinetics of AL-335). ... Adafosbuvir is under investigation in clinical trial NCT02894905 (A Study to Evaluate the Effect of Renal …

N-(3-(8-CYANO-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZIN-2-YLAMINO)PHENYL)ACETAMIDE

Experimental

N-(2-Aminoethyl)-1-aziridineethanamine

First described in the literature in 2004, N-(2-Aminoethyl)-1-aziridineethanamine is an experimental angiotensin converting enzyme 2 inhibitor investigated for its use in treating cardiovascular disease and its activity against Severe Acute Respiratory Syndrome (SARS).
Experimental

Norgestrienone

Experimental
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Amineptine

The Food and Drug Administration suspended the marketing authorisation for Survector in 1999 and France withdrew it from the market, however several developing countries continued to produce it up until 2005.
Illicit
Withdrawn
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Mosapride

Mosapride is under investigation for the treatment and prevention of Postoperative Ileus and Gastric Peroral Endoscopic Pyloromyotomy (G-POEM). Mosapride has been investigated for the treatment and diagnostic of Constipation, Type 2 Diabetes, Functional Dyspepsia, Functional Constipation, and Epigastric Pain Syndrome, among others.
Investigational
Matched Description: … Mosapride is under investigation for the treatment and prevention of Postoperative Ileus and Gastric ... Mosapride has been investigated for the treatment and diagnostic of Constipation, Type 2 Diabetes, Functional …
Matched Mixtures name: … GASPRID-S …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Piperine

Bioperine has been used in trials studying the treatment of Multiple Myeloma and Deglutition Disorders.
Investigational
Matched Description: … Bioperine has been used in trials studying the treatment of Multiple Myeloma and Deglutition Disorders …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …

Demegestone

Demegestone is a progesterone receptor agonist that was previously used to treat luteal insufficiency. It was previously marketed in France as Lutionex, but has since been discontinued.
Experimental
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Amelubant

Investigational

Hydroxyprogesterone

Experimental
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Displaying drugs 4826 - 4850 of 10656 in total