Displaying drugs 4951 - 4975 of 5929 in total
3-Amino-4,5-Dihydroxy-Cyclohex-1-Enecarboxylate
Experimental
Matched Name: … 3-Amino-4,5-Dihydroxy-Cyclohex-1-Enecarboxylate …
Matched Iupac: … (3S,4R,5R)-3-amino-4,5-dihydroxycyclohex-1-ene-1-carboxylate …
Matched Iupac: … (3S,4R,5R)-3-amino-4,5-dihydroxycyclohex-1-ene-1-carboxylate …
5,6-Dihydro-Benzo[H]Cinnolin-3-Ylamine
Experimental
Matched Name: … 5,6-Dihydro-Benzo[H]Cinnolin-3-Ylamine …
Matched Iupac: … 5H,6H-benzo[h]cinnolin-3-amine …
Matched Iupac: … 5H,6H-benzo[h]cinnolin-3-amine …
(1R)-3-chloro-1-phenylpropan-1-ol
Experimental
Matched Name: … (1R)-3-chloro-1-phenylpropan-1-ol …
Matched Iupac: … (1R)-3-chloro-1-phenylpropan-1-ol …
Matched Iupac: … (1R)-3-chloro-1-phenylpropan-1-ol …
N-3-OXO-DODECANOYL-L-HOMOSERINE LACTONE
Experimental
Matched Name: … N-3-OXO-DODECANOYL-L-HOMOSERINE LACTONE …
Matched Iupac: … 3-oxo-N-[(3S)-2-oxooxolan-3-yl]dodecanamide …
Matched Iupac: … 3-oxo-N-[(3S)-2-oxooxolan-3-yl]dodecanamide …
CP-271485
Experimental
Matched Synonyms: … (6S)-4-Benzyl-6-(1-methyl-2,2-dioxido-1,3-dihydro-2,1-benzothiazol-5-yl)-3-morpholinone …
Perospirone
Perospirone is an atypical or second-generation antipsychotic of the azapirone family that antagonizes serotonin 5HT2A receptors and dopamine D2 receptors. It also displays affinity towards 5HT1A receptors as a partial agonist. Dainippon Sumitomo Pharma developed perospirone in Japan in 2001 for the treatment of acute schizophrenia and bipolar mania as...
Experimental
Matched Synonyms: … cis-N-(4-(4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl)butyl)-1,2-cyclohexanedicarboximide …
Matched Iupac: … (3aR,7aS)-2-{4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl}-octahydro-1H-isoindole-1,3-dione …
Matched Description: … dopamine D2 receptors. ... second-generation antipsychotic of the azapirone family that antagonizes serotonin 5HT2A receptors and ... Dainippon Sumitomo Pharma developed perospirone in Japan in 2001 for the treatment of acute schizophrenia and …
Matched Categories: … Dopamine D2 Receptor Antagonists …
Matched Iupac: … (3aR,7aS)-2-{4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl}-octahydro-1H-isoindole-1,3-dione …
Matched Description: … dopamine D2 receptors. ... second-generation antipsychotic of the azapirone family that antagonizes serotonin 5HT2A receptors and ... Dainippon Sumitomo Pharma developed perospirone in Japan in 2001 for the treatment of acute schizophrenia and …
Matched Categories: … Dopamine D2 Receptor Antagonists …
Dimetacrine
Dimetacrine is also known as dimethacrine or acripamine. It is marketed under the names Istonil, Istonyl, Linostil, and Miroistonil. Dimetacrine is a tricyclic antidepressant (TCA) with imipramine-like effects used in Europe for the treatment of depression. Dimetacrine is no longer used in Japan.
Experimental
Withdrawn
Matched Synonyms: … 3-(9,9-dimethylacridin-10-yl)-N,N-dimethyl-propan-1-amine …
Matched Iupac: … [3-(9,9-dimethyl-9,10-dihydroacridin-10-yl)propyl]dimethylamine …
Matched Description: … It is marketed under the names Istonil, Istonyl, Linostil, and Miroistonil. …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Iupac: … [3-(9,9-dimethyl-9,10-dihydroacridin-10-yl)propyl]dimethylamine …
Matched Description: … It is marketed under the names Istonil, Istonyl, Linostil, and Miroistonil. …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Dihydroxymethoxychalcone
Cardamonin (also known as Dihydroxymethoxychalcone), as shown by the increasing number of publications, has received growing attention from the scientific community due to the expectations toward its benefits to human health. Cardamonin's name comes from the fact that it can be found in cardamom spice.
Experimental
Matched Synonyms: … (E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenyl-2-propen-1-one …
Matched Iupac: … (2E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one …
Matched Description: … the increasing number of publications, has received growing attention from the scientific community due …
Matched Iupac: … (2E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one …
Matched Description: … the increasing number of publications, has received growing attention from the scientific community due …
Mavacamten
Mavacamten is a myosin inhibitor indicated for the treatment of adults with symptomatic New York Heart Association (NYHA) class II-III obstructive hypertrophic cardiomyopathy (HCM). It received initial US FDA approval in 2022, and it is one of the first myosin inhibitors to be used in humans. Mavacamten was also approved...
Approved
Investigational
Matched Synonyms: … 6-(((1S)-1-Phenylethyl)amino)-3-(propan-2-yl)-1,2,3,4 tetrahydropyrimidine-2,4-dione …
Matched Iupac: … 6-{[(1S)-1-phenylethyl]amino}-3-(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … It received initial US FDA approval in 2022, and it is one of the first myosin inhibitors to be used ... [A248440] Mavacamten was also approved by Health Canada in October 2022 and by EMA in July 2023 for the …
Matched Iupac: … 6-{[(1S)-1-phenylethyl]amino}-3-(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … It received initial US FDA approval in 2022, and it is one of the first myosin inhibitors to be used ... [A248440] Mavacamten was also approved by Health Canada in October 2022 and by EMA in July 2023 for the …
VLX-1570
VLX-1570 is under investigation in clinical trial NCT02372240 (A Study of VLX1570 and Dexamethasone in Myeloma Patients).
Investigational
Matched Synonyms: … (3E,5E)-3,5-Bis[(4-Fluoro-3-Nitrophenyl)Methylidene]-1-(Prop-2-Enoyl)Azepan-4-0Ne …
Matched Iupac: … (3E,5E)-3,5-bis[(4-fluoro-3-nitrophenyl)methylidene]-1-(prop-2-enoyl)azepan-4-one …
Matched Description: … VLX-1570 is under investigation in clinical trial NCT02372240 (A Study of VLX1570 and Dexamethasone in …
Matched Iupac: … (3E,5E)-3,5-bis[(4-fluoro-3-nitrophenyl)methylidene]-1-(prop-2-enoyl)azepan-4-one …
Matched Description: … VLX-1570 is under investigation in clinical trial NCT02372240 (A Study of VLX1570 and Dexamethasone in …
Inosine pranobex
Inosine pranobex (Isoprinosine or Methisoprinol) is a combination of inosine, acetamidobenzoic acid, and dimethylaminoisopropanol used as an antiviral drug.
Approved
Matched Synonyms: … Inosine-2-hydroxypropyldimethylammonium 4-acetamidobenzoate (1:3) …
Matched Iupac: … tris((2R)-1-(dimethylamino)propan-2-ol); tris(4-acetamidobenzoic acid); 9-[(2R,3R,4S,5R)-3,4-dihydroxy …
Matched Description: … Inosine pranobex (Isoprinosine or Methisoprinol) is a combination of inosine, acetamidobenzoic acid, ... and dimethylaminoisopropanol used as an antiviral drug. …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … tris((2R)-1-(dimethylamino)propan-2-ol); tris(4-acetamidobenzoic acid); 9-[(2R,3R,4S,5R)-3,4-dihydroxy …
Matched Description: … Inosine pranobex (Isoprinosine or Methisoprinol) is a combination of inosine, acetamidobenzoic acid, ... and dimethylaminoisopropanol used as an antiviral drug. …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Fluoxymesterone
An anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males, and in the treatment of breast neoplasms in women.
Approved
Illicit
Matched Synonyms: … 11β,17β-Dihydroxy-9α-fluoro-17α-methyl-4-androster-3-one ... 9-Fluoro-11β,17β-dihydroxy-17-methylandrost-4-en-3-one …
Matched Iupac: … (1S,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-1,10-dihydroxy-1,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H …
Matched Description: … anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males, and …
Matched Categories: … 3-Oxoandrosten (4) Derivatives ... Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Matched Iupac: … (1S,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-1,10-dihydroxy-1,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H …
Matched Description: … anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males, and …
Matched Categories: … 3-Oxoandrosten (4) Derivatives ... Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Eteplirsen
Eteplirsen is a synthetic antisense oligonucleotide and a phosphorodiamidate morpholino oligomer. It consists of a six-membered morpholino ring replacing the five-membered ribofuranosyl rings found in natural DNA and RNA. Duchenne muscular dystrophy is a rare genetic disorder characterized by progressive muscle deterioration and premature death most commonly due to respiratory...
Approved
Investigational
Matched Synonyms: … (P-deoxy-P-(dimethylamino)](2',3'-dideoxy-2',3'-imino-2',3'-seco)(2'a→5')(C-m5U-C-C-A-A-C-A-m5U-C-A-A-G-G-A-A-G-A-m5U-G-G-C-A-m5U-m5U-m5U-C-m5U-A-G …
Matched Description: … and RNA. ... Eteplirsen is a synthetic antisense oligonucleotide and a phosphorodiamidate morpholino oligomer. ... Duchenne muscular dystrophy is a rare genetic disorder characterized by progressive muscle deterioration and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Description: … and RNA. ... Eteplirsen is a synthetic antisense oligonucleotide and a phosphorodiamidate morpholino oligomer. ... Duchenne muscular dystrophy is a rare genetic disorder characterized by progressive muscle deterioration and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Aminophenazone
Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties that carries a risk of agranulocytosis. In biomedical applications, radiolabelled (13C-labeled) aminophenazone has been used in breath tests to measure the cytochrome P-450 metabolic activity in liver function tests. The FDA suspended the use of aminophenazone due to its association...
Approved
Withdrawn
Matched Synonyms: … 4-(Dimethylamino)-1,2-dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one ... 4-(Dimethylamino)-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one ... 1,5-Dimethyl-4-dimethylamino-2-phenyl-3-pyrazolone …
Matched Iupac: … 4-(dimethylamino)-1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one …
Matched Description: … Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties that carries ... The FDA suspended the use of aminophenazone due to its association with agranulocytosis, a life-threatening …
Matched Iupac: … 4-(dimethylamino)-1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one …
Matched Description: … Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties that carries ... The FDA suspended the use of aminophenazone due to its association with agranulocytosis, a life-threatening …
PCLX-001
PCLX-001 is a first-in-kind N-Myristoyltransferase (NMT) inhibitor being developed by Pacylex Pharmaceuticals (https://pacylex.com). Current studies have shown that PCLX-001 works differently than other known cancer drugs and has high activity and positive results in breast, lung, bladder and pancreas cancers.
Investigational
Matched Synonyms: … 2,6-Dichloro-N-(1,5-dimethyl-3-(2-methylpropyl)-1H-pyrazol-4-yl)-4-(2-(1-piperazinyl)-4-pyridinyl)benzenesulfonamide ... 2,6-Dichloro-N-(3-isobutyl-1,5-dimethyl-1H-pyrazol-4-yl)-4-(2-(piperazin-1-yl)pyridin-4-yl)benzenesulfonamide …
Matched Description: … activity and positive results in breast, lung, bladder and pancreas cancers. ... Current studies have shown that PCLX-001 works differently than other known cancer drugs and has high …
Matched Description: … activity and positive results in breast, lung, bladder and pancreas cancers. ... Current studies have shown that PCLX-001 works differently than other known cancer drugs and has high …
Bioymifi
Bioymifi is a small molecule that acts as a tumor necrosis factor-related apoptosis-induced ligand (TRAIL) mimetic. Upon binding to the death receptor 5 (DR5) on cancer cells, bioymifi triggers apoptosis, possibly through a caspase-dependent pathway. Bioymifi is currently being investigated as an anti-tumor agent.[A257048,A257053]
Investigational
Matched Synonyms: … 5-(5-((3-(4-bromophenyl)-2-imino-4-oxothiazolidin-5-ylidene)methyl)furan-2-yl)isoindoline-1,3-dione ... 5-[5-[(Z)-[3-(4-bromophenyl)-2-imino-4-oxo-1,3-thiazolidin-5-ylidene]methyl]furan-2-yl]isoindole-1,3- …
Matched Iupac: … 6-(5-{[(5Z)-3-(4-bromophenyl)-2-imino-4-oxo-1,3-thiazolidin-5-ylidene]methyl}furan-2-yl)-3-hydroxy-1H-isoindol …
Matched Description: … Upon binding to the death receptor 5 (DR5) on cancer cells, bioymifi triggers apoptosis, possibly through …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic ... Phthalic Acids …
Matched Iupac: … 6-(5-{[(5Z)-3-(4-bromophenyl)-2-imino-4-oxo-1,3-thiazolidin-5-ylidene]methyl}furan-2-yl)-3-hydroxy-1H-isoindol …
Matched Description: … Upon binding to the death receptor 5 (DR5) on cancer cells, bioymifi triggers apoptosis, possibly through …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic ... Phthalic Acids …
PF-07059013
Investigational
Matched Synonyms: … 2(1h)-pyridinone, 6-((1s)-1-((2-amino-6-fluoro-3-quinolinyl)oxy)ethyl)-5-(1h-pyrazol-1-yl)- ... 6-((1s)-1-((2-amino-6-fluoroquinolin-3-yl)oxy)ethyl)-5-(1h-pyrazol-1-yl)pyridin-2(1h)-one …
Matched Iupac: … 6-[(1S)-1-[(2-amino-6-fluoroquinolin-3-yl)oxy]ethyl]-5-(1H-pyrazol-1-yl)-1,2-dihydropyridin-2-one …
Matched Iupac: … 6-[(1S)-1-[(2-amino-6-fluoroquinolin-3-yl)oxy]ethyl]-5-(1H-pyrazol-1-yl)-1,2-dihydropyridin-2-one …
6-Hydroxy-6-Methyl-Heptan-3-One
Experimental
Matched Name: … 6-Hydroxy-6-Methyl-Heptan-3-One …
Matched Iupac: … 6-hydroxy-6-methylheptan-3-one …
Matched Iupac: … 6-hydroxy-6-methylheptan-3-one …
1-(4-Amidinophenyl)-3-(4-Chlorophenyl)Urea
Experimental
Matched Name: … 1-(4-Amidinophenyl)-3-(4-Chlorophenyl)Urea …
Matched Iupac: … 3-(4-carbamimidoylphenyl)-1-(4-chlorophenyl)urea …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Iupac: … 3-(4-carbamimidoylphenyl)-1-(4-chlorophenyl)urea …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
2-(3-METHYLPHENYL)-1H-INDOLE-5-CARBOXIMIDAMIDE
Experimental
Matched Name: … 2-(3-METHYLPHENYL)-1H-INDOLE-5-CARBOXIMIDAMIDE …
Matched Iupac: … 2-(3-methylphenyl)-1H-indole-5-carboximidamide …
Matched Iupac: … 2-(3-methylphenyl)-1H-indole-5-carboximidamide …
3-(4-NITRO-PHENOXY)-PROPAN-1-OL
Experimental
Matched Name: … 3-(4-NITRO-PHENOXY)-PROPAN-1-OL …
Matched Iupac: … 3-(4-nitrophenoxy)propan-1-ol …
Matched Iupac: … 3-(4-nitrophenoxy)propan-1-ol …
(2R)-3-[(tetrahydroxyphosphoranyl)oxy]-1,2-propanediyl dibutanoate
Experimental
Matched Name: … (2R)-3-[(tetrahydroxyphosphoranyl)oxy]-1,2-propanediyl dibutanoate …
Matched Iupac: … (2R)-1-(butanoyloxy)-3-[(tetrahydroxy-lambda5-phosphanyl)oxy]propan-2-yl butanoate …
Matched Iupac: … (2R)-1-(butanoyloxy)-3-[(tetrahydroxy-lambda5-phosphanyl)oxy]propan-2-yl butanoate …
(2S)-2-amino-3-phenylpropane-1,1-diol
Experimental
Matched Name: … (2S)-2-amino-3-phenylpropane-1,1-diol …
Matched Iupac: … (2S)-2-amino-3-phenylpropane-1,1-diol …
Matched Iupac: … (2S)-2-amino-3-phenylpropane-1,1-diol …
2-(1H-pyrazol-3-yl)-1H-benzimidazole
Experimental
Matched Name: … 2-(1H-pyrazol-3-yl)-1H-benzimidazole …
Matched Iupac: … 2-(1H-pyrazol-3-yl)-1H-1,3-benzodiazole …
Matched Iupac: … 2-(1H-pyrazol-3-yl)-1H-1,3-benzodiazole …
N-(4-sulfamoylphenyl)-1H-indazole-3-carboxamide
Experimental
Matched Name: … N-(4-sulfamoylphenyl)-1H-indazole-3-carboxamide …
Matched Iupac: … N-(4-sulfamoylphenyl)-1H-indazole-3-carboxamide …
Matched Iupac: … N-(4-sulfamoylphenyl)-1H-indazole-3-carboxamide …
Displaying drugs 4951 - 4975 of 5929 in total