Displaying drugs 26 - 50 of 192 in total
Human cord blood hematopoietic progenitor cell
Human cord blood hematopoietic progenitor cells consist of hematopoietic progenitor cells, monocytes, lymphocytes, and granulocytes from human cord blood. They are used during allogeneic unrelated and related hematopoietic stem cell transplantation procedures in patients with disorders affecting the hematopoietic system that are inherited, acquired, or result from myeloablative treatment. Human...
Approved
Matched Name: … Human cord blood hematopoietic progenitor cell …
Matched Description: … marrow transplantation; it allows shorter time to transplant and tolerance of 1–2 human leukocyte antigen ... Human umbilical cord is a rich source of hematopoietic stem cells and progenitor cells that are capable ... lymphocytes, and granulocytes from human cord blood. …
Matched Description: … marrow transplantation; it allows shorter time to transplant and tolerance of 1–2 human leukocyte antigen ... Human umbilical cord is a rich source of hematopoietic stem cells and progenitor cells that are capable ... lymphocytes, and granulocytes from human cord blood. …
Rosuvastatin
Rosuvastatin, also known as the brand name product Crestor, is a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. More specifically, statin medications...
Approved
Matched Synonyms: … (3R,5S,6E)-7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(ethyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5- ... (3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept ... -6-enoic acid …
Matched Iupac: … (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept ... -6-enoic acid …
Matched Description: … for people with a moderate to high risk of development of CVD, such as those with Type 2 Diabetes. ... event occurring within 5 years) statins cause a 20%-22% relative reduction in major cardiovascular events ... (heart attack, stroke, coronary revascularization, and coronary death) for every 1 mmol/L reduction …
Matched Salts cas: … 147098-20-2 ... 953412-08-3 …
Matched Mixtures name: … ROSUVASTATINA E OMEGA 3 SPA SOCIET PRODOTTI ANTIBIOTICI ... ROSUVASTATINA E OMEGA 3 SPA SOCIET PRODOTTI ANTIBIOTICI ... Rosuvastatin and Ezetimibe …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Inhibitors ... Cytochrome P-450 CYP2C9 Substrates ... Cytochrome P-450 CYP3A Substrates …
Matched Products: … ROSUVASTATIN 1 A 5MG ... ROSUVASTATIN 1 A 10MG ... ROSUVASTATIN 1 A 20MG …
Matched Iupac: … (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept ... -6-enoic acid …
Matched Description: … for people with a moderate to high risk of development of CVD, such as those with Type 2 Diabetes. ... event occurring within 5 years) statins cause a 20%-22% relative reduction in major cardiovascular events ... (heart attack, stroke, coronary revascularization, and coronary death) for every 1 mmol/L reduction …
Matched Salts cas: … 147098-20-2 ... 953412-08-3 …
Matched Mixtures name: … ROSUVASTATINA E OMEGA 3 SPA SOCIET PRODOTTI ANTIBIOTICI ... ROSUVASTATINA E OMEGA 3 SPA SOCIET PRODOTTI ANTIBIOTICI ... Rosuvastatin and Ezetimibe …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Inhibitors ... Cytochrome P-450 CYP2C9 Substrates ... Cytochrome P-450 CYP3A Substrates …
Matched Products: … ROSUVASTATIN 1 A 5MG ... ROSUVASTATIN 1 A 10MG ... ROSUVASTATIN 1 A 20MG …
Histrelin
Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin when administered as an implant delivering continuous therapeutic doses. This drug is a synthetic analog of naturally occurring GnRH with a higher potency. Histrelin implants are non-biodegradable, diffusion-controlled, hydrogel polymer reservoirs containing histrelin acetate that...
Approved
Withdrawn
Matched Synonyms: … 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-1-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide ... 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-Nτ-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide …
Matched Iupac: … (2S)-1-[(2S)-2-[(2S)-2-[(2R)-3-(1-benzyl-1H-imidazol-4-yl)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)- ... 3-(1H-imidazol-4-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido ... ]propanamido]-3-(4-hydroxyphenyl)propanamido]propanamido]-4-methylpentanamido]-5-carbamimidamidopentanoyl ... ]-N-ethylpyrrolidine-2-carboxamide; bis(acetic acid) …
Matched Description: … treatment for children with central precocious puberty (CPP) due to their capacity to reduce LH levels and ... This drug is a synthetic analog of naturally occurring GnRH with a higher potency. ... Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin …
Matched Categories: … Hormones and Related Agents ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Iupac: … (2S)-1-[(2S)-2-[(2S)-2-[(2R)-3-(1-benzyl-1H-imidazol-4-yl)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)- ... 3-(1H-imidazol-4-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido ... ]propanamido]-3-(4-hydroxyphenyl)propanamido]propanamido]-4-methylpentanamido]-5-carbamimidamidopentanoyl ... ]-N-ethylpyrrolidine-2-carboxamide; bis(acetic acid) …
Matched Description: … treatment for children with central precocious puberty (CPP) due to their capacity to reduce LH levels and ... This drug is a synthetic analog of naturally occurring GnRH with a higher potency. ... Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin …
Matched Categories: … Hormones and Related Agents ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Lovastatin
Lovastatin, also known as the brand name product Mevacor, is a lipid-lowering drug and fungal metabolite derived synthetically from a fermentation product of Aspergillus terreus. Originally named Mevinolin, lovastatin belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid...
Approved
Investigational
Matched Synonyms: … (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(2R,4R)-(tetrahydro-4-hydroxy-6-oxo-2H-pyran ... -2-yl)ethyl)-1-naphthalenyl (S)-2-methyl-butyrate ... 2β,6α-dimethyl-8alpha-(2-methyl-1-oxobutoxy)-mevinic acid lactone …
Matched Iupac: … (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen ... -1-yl (2S)-2-methylbutanoate …
Matched Description: … for people with a moderate to high risk of development of CVD, such as those with Type 2 Diabetes. ... (heart attack, stroke, coronary revascularization, and coronary death) for every 1 mmol/L reduction ... event occurring within 5 years) statins cause a 20%-22% relative reduction in major cardiovascular events …
Matched Categories: … lovastatin and nicotinic acid ... P-glycoprotein inhibitors ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP2C8 Substrates …
Matched Iupac: … (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen ... -1-yl (2S)-2-methylbutanoate …
Matched Description: … for people with a moderate to high risk of development of CVD, such as those with Type 2 Diabetes. ... (heart attack, stroke, coronary revascularization, and coronary death) for every 1 mmol/L reduction ... event occurring within 5 years) statins cause a 20%-22% relative reduction in major cardiovascular events …
Matched Categories: … lovastatin and nicotinic acid ... P-glycoprotein inhibitors ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP2C8 Substrates …
Antihemophilic factor human
Antihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential component of the coagulation cascade. Antihemophilic factor is manufactured with reduced amounts of von Willebrand Factor antigen (VWF:Ag) and purified from extraneous plasma-derived...
Approved
Matched Synonyms: … F8 protein, human ... factor VIII, human ... Factor VIII (human) …
Matched Name: … Antihemophilic factor human …
Matched Description: … Antihemophilic factor human is approved by the Food and Drug Administration for use in hemophilia A ( ... Antihemophilic factor is manufactured with reduced amounts of von Willebrand Factor antigen (VWF:Ag) ... as a result, leads to easy bruising and bleeding. …
Matched Mixtures name: … BERIPLAST-P COMBI SET 3 ML TROMBİN ÇÖZELTİSİ VE 1 ML FİBRİNOJEN ÇÖZELTİSİ İÇEREN FİBRİN YAPIŞTIRICI ... Haemate P Powder and solvent for solution for injection or infusion ... BERIPLAST-P COMBI SET 1 ML TROMBİN ÇÖZELTİSİ VE 1 ML FİBRİNOJEN ÇÖZELTİSİ İÇEREN FİBRİN YAPIŞTIRICI …
Matched Categories: … Hemophilia A ... Human Antihemophilic Factors ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … FACTANE 500 IU/5 ML IV ENJ ICIN LIYOFIZE TOZ ICEREN FLAKON, 1 ADET ... Monoclate-P ... KOATE-DVI FOR INJECTION 250 iu/5 ml …
Matched Name: … Antihemophilic factor human …
Matched Description: … Antihemophilic factor human is approved by the Food and Drug Administration for use in hemophilia A ( ... Antihemophilic factor is manufactured with reduced amounts of von Willebrand Factor antigen (VWF:Ag) ... as a result, leads to easy bruising and bleeding. …
Matched Mixtures name: … BERIPLAST-P COMBI SET 3 ML TROMBİN ÇÖZELTİSİ VE 1 ML FİBRİNOJEN ÇÖZELTİSİ İÇEREN FİBRİN YAPIŞTIRICI ... Haemate P Powder and solvent for solution for injection or infusion ... BERIPLAST-P COMBI SET 1 ML TROMBİN ÇÖZELTİSİ VE 1 ML FİBRİNOJEN ÇÖZELTİSİ İÇEREN FİBRİN YAPIŞTIRICI …
Matched Categories: … Hemophilia A ... Human Antihemophilic Factors ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … FACTANE 500 IU/5 ML IV ENJ ICIN LIYOFIZE TOZ ICEREN FLAKON, 1 ADET ... Monoclate-P ... KOATE-DVI FOR INJECTION 250 iu/5 ml …
Gallium Ga-68 gozetotide
Gallium (Ga) 68 prostate-specific membrane antigen (PSMA)-11, or Ga-68 gozetotide, is a radiopharmaceutical agent used to identify and assess prostate-specific membrane antigen (PSMA)-positive lesions in adult men with prostate cancer during positron emission tomography (PET). Prostate cancer is one of the most commonly diagnosed cancers among men in Western countries...
Approved
Matched Iupac: … (68Ga)gallium(3+) 3-(3-{[(2-{[(5-{2-[(5-{[(5S)-5-carboxy-5-({[(1S)-1,3-dicarboxypropyl]carbamoyl}amino ... )amino]methyl}-4-hydroxyphenyl)propanoate ... )pentyl]carbamoyl}pentyl)carbamoyl]ethyl}-2-hydroxyphenyl)methyl](carboxylatomethyl)amino}ethyl)(carboxylatomethyl …
Matched Description: … Gallium (Ga) 68 prostate-specific membrane antigen (PSMA)-11, or Ga-68 gozetotide, is a radiopharmaceutical ... agent used to identify and assess prostate-specific membrane antigen (PSMA)-positive lesions in adult ... [L27006] On December 1, 2020, Ga-68 PSMA-11 was approved by the FDA as the first molecular-targeted …
Matched Categories: … Indicators and Reagents ... Compounds used in a research, industrial, or household setting …
Matched Description: … Gallium (Ga) 68 prostate-specific membrane antigen (PSMA)-11, or Ga-68 gozetotide, is a radiopharmaceutical ... agent used to identify and assess prostate-specific membrane antigen (PSMA)-positive lesions in adult ... [L27006] On December 1, 2020, Ga-68 PSMA-11 was approved by the FDA as the first molecular-targeted …
Matched Categories: … Indicators and Reagents ... Compounds used in a research, industrial, or household setting …
Lifitegrast
Lifitegrast is a FDA approved drug for the treatment of keratoconjunctivitis sicca (dry eye syndrome). It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist that was discovered through the rational design process. The ophthalmic solution was approved in July, 2016 under the trade name Xiidra. It has...
Approved
Matched Iupac: … (2S)-2-{[2-(1-benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinolin-6-yl]formamido}-3-(3- …
Matched Description: … It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist ... Lifitegrast is a FDA approved drug for the treatment of keratoconjunctivitis sicca (dry eye syndrome) ... onset of action and well tolerated profile in both local and systemic setting [A18805]. …
Matched Categories: … Lymphocyte Function-Associated Antigen-1 ... Lymphocyte Function-Associated Antigen-1 Antagonist ... Lymphocyte Function-Associated Antigen-1 Antagonists ... Amino Acids, Peptides, and Proteins ... Compounds used in a research, industrial, or household setting …
Matched Description: … It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist ... Lifitegrast is a FDA approved drug for the treatment of keratoconjunctivitis sicca (dry eye syndrome) ... onset of action and well tolerated profile in both local and systemic setting [A18805]. …
Matched Categories: … Lymphocyte Function-Associated Antigen-1 ... Lymphocyte Function-Associated Antigen-1 Antagonist ... Lymphocyte Function-Associated Antigen-1 Antagonists ... Amino Acids, Peptides, and Proteins ... Compounds used in a research, industrial, or household setting …
Antilymphocyte immunoglobulin (horse)
Equine anti-thymocyte globulin is composed of purified gamma globulin containing primarily IgG against human thymus lymphocytes. It is formed by inoculating a horse with an antigen (human thymoyctes) which then induces the horse immune system's B-lymphocytes to produce IgG immunoglobulins specific for that antigen. The result is polyclonal IgG that...
Approved
Investigational
Matched Description: … It is formed by inoculating a horse with an antigen (human thymoyctes) which then induces the horse immune ... in the type of antigen product used to produce immunoglobulin (thymocytes, peripheral T cells, etc.) ... Equine anti-thymocyte globulin is composed of purified gamma globulin containing primarily IgG against human …
Matched Categories: … Immunoglobulin G ... Fluids and Secretions ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … EQUAGAM 50 MG/ML İNFÜZYONLUK ÇÖZELTİ İÇEREN KONSANTRESİ, 5 ADET …
Matched Categories: … Immunoglobulin G ... Fluids and Secretions ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … EQUAGAM 50 MG/ML İNFÜZYONLUK ÇÖZELTİ İÇEREN KONSANTRESİ, 5 ADET …
SARS-CoV-2 virus recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer (B.1.351-B.1.1.7 strains)
Bimervax is an adjuvanted non-mRNA COVID-19 vaccine utilizing a SARS-CoV-2 recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer. It is intended to elicit protection against Omicron XBB.1.5, one of the dominant circulating SARS-CoV-2 subvariants in 2023. It is produced using recombinant DNA technology in CHO cell lines and...
Approved
Matched Synonyms: … SARS-CoV-2 virus recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer – B.1.351 …
Matched Name: … SARS-CoV-2 virus recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer (B.1.351 …
Matched Description: … Bimervax is an adjuvanted non-mRNA COVID-19 vaccine utilizing a SARS-CoV-2 recombinant spike (S) protein ... Human Health S.L. for the European market. ... [A262551] It is produced using recombinant DNA technology in CHO cell lines and is marketed by Hipra …
Matched Name: … SARS-CoV-2 virus recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer (B.1.351 …
Matched Description: … Bimervax is an adjuvanted non-mRNA COVID-19 vaccine utilizing a SARS-CoV-2 recombinant spike (S) protein ... Human Health S.L. for the European market. ... [A262551] It is produced using recombinant DNA technology in CHO cell lines and is marketed by Hipra …
Hydrocortisone acetate
Approved
Vet approved
Matched Iupac: … ,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate ... 2-[(1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H …
Matched Mixtures name: … FUCIDIN H %2 + %1 KREM, 30 G ... CORTIFENOL H POMADA OFTALMICA 4 G ... UREACORT %0,5 + %5 KREM (30 G) …
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C8 Inducers ... Cytochrome P-450 CYP3A Inducers …
Matched Products: … Poli-A ... Topiderm HC 2% ... American Safety and First Aid …
Matched Mixtures name: … FUCIDIN H %2 + %1 KREM, 30 G ... CORTIFENOL H POMADA OFTALMICA 4 G ... UREACORT %0,5 + %5 KREM (30 G) …
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C8 Inducers ... Cytochrome P-450 CYP3A Inducers …
Matched Products: … Poli-A ... Topiderm HC 2% ... American Safety and First Aid …
Talimogene laherparepvec
Talimogene laherparepvec is an oncolytic treatment used in local treatment of unresectable cutaneous, subcutaneous, and nodal lesions in patients with recurrent melanoma. It is a genetically administered herpes simplex virus 1 (HSV-1) that expresses human cytokine granulocyte-macrophage colony stimulating factor (GM-CSF) with antitumor and immune-stimulating activities. It specifically replicates within...
Approved
Experimental
Investigational
Matched Description: … It is a genetically administered herpes simplex virus 1 (HSV-1) that expresses human cytokine granulocyte-macrophage ... It specifically replicates within tumor cells and causes lysis. ... colony stimulating factor (GM-CSF) with antitumor and immune-stimulating activities. …
Matched Categories: … Antineoplastic cell and gene therapy ... Antineoplastic and Immunomodulating Agents …
Matched Categories: … Antineoplastic cell and gene therapy ... Antineoplastic and Immunomodulating Agents …
Abatacept
Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1).[L20504,L42715] Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it...
Approved
Matched Description: … antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin ... of 92,300 Da and it is a homodimer of two homologous polypeptide chains of 357 amino acids each. ... Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … ORENCIA SUBKUTAN 125 MG ENJEKSIYONLUK COZELTI ICEREN KULLANIMA HAZIR ENJEKTOR 4 ADET …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … ORENCIA SUBKUTAN 125 MG ENJEKSIYONLUK COZELTI ICEREN KULLANIMA HAZIR ENJEKTOR 4 ADET …
Bevacizumab
There is a great deal of evidence indicating that vascular endothelial growth factor (VEGF) is important for the survival and proliferation of cancer cells.[A192939,A192837,A192891,A193275] VEGF plays an important role in angiogenesis, lymphangiogenesis, and tumor growth, which are all factors that contribute to its attractiveness as a therapeutic target for anti-cancer...
Approved
Investigational
Matched Description: … [A193272,A193275] It is a humanized monoclonal IgG antibody, and inhibits angiogenesis by binding and ... neutralizing VEGF-A. ... generally indicated for use in combination with different chemotherapy regimens which are specific to the type …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … ZİRABEV 100 MG/4 ML İNFÜZYONLUK ÇÖZELTİ, 1 ADET ... MVASİ 100 MG/4 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET ... BEVAX 100MG/4 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … ZİRABEV 100 MG/4 ML İNFÜZYONLUK ÇÖZELTİ, 1 ADET ... MVASİ 100 MG/4 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET ... BEVAX 100MG/4 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET …
Efalizumab
Humanized IgG1 kappa isotype monoclonal antibody that binds to human CD11a. Efalizumab has a molecular weight of approximately 150 kilodaltons and is produced in a Chinese hamster ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin. The FDA approved efalizumab in 2003. It was later withdrawn...
Approved
Investigational
Withdrawn
Matched Description: … Efalizumab has a molecular weight of approximately 150 kilodaltons and is produced in a Chinese hamster ... Humanized IgG1 kappa isotype monoclonal antibody that binds to human CD11a. ... ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Avelumab
Avelumab is a human IgG1 lambda monoclonal antibody that binds programmed cell death ligand-1 (PD-L1) to block its interaction with its receptors found on T cells and antigen-presenting cells. Avelumab was first approved by the FDA on March 23, 2017. On September 18 and December 18 of the same year,...
Approved
Investigational
Matched Description: … Avelumab is a human IgG1 lambda monoclonal antibody that binds programmed cell death ligand-1 (PD-L1) ... to block its interaction with its receptors found on T cells and antigen-presenting cells. ... ] and Health Canada,[L48171] respectively. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors ... PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors …
Matched Products: … BAVENCIO 200 MG/10 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 FLAKON …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors ... PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors …
Matched Products: … BAVENCIO 200 MG/10 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 FLAKON …
Bulevirtide
Hepatitis D is considered the most severe type of viral hepatitis and leads to the rapid development of cirrhosis, severe decompensation of liver function, and an increased risk of mortality.[A226340,L30235] Until recently, there have been extremely limited treatments available for Hepatitis D infection. Bulevirtide, also known as Hepcludex, is a...
Approved
Investigational
Matched Description: … Hepatitis D is considered the most severe type of viral hepatitis and leads to the rapid development ... [A226305]
Bulevirtide, also known as Hepcludex, is a first-in-class entry inhibitor for the treatment ... of cirrhosis, severe decompensation of liver function, and an increased risk of mortality. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Apalutamide
Apalutamide is a potent androgen receptor (AR) antagonist that selectively binds to the ligand-binding domain of AR and blocks AR nuclear translocation or binding to androgen response elements . It has been used in trials studying the treatment of Prostate Cancer, Hepatic Impairment, Prostatic Neoplasms, Castration-Resistant Prostate Cancer, and Prostatic...
Approved
Investigational
Matched Iupac: … 4-{7-[6-cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-sulfanylidene-5,7-diazaspiro[3.4]octan-5-yl}-2 …
Matched Description: … Higher prostate-specific antigen (PSA) and shorter PSA doubling time (PSA DT) are associated with a higher ... In a phase-2 multicenter open-label study, 89% of patients with non-metastatic, castration-resistant ... In mice bearing human CRPC xenograft models, apalutamide treatment produced tumor regressions in a dose-dependent …
Matched Categories: … MATE 2 Inhibitors ... MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents …
Matched Description: … Higher prostate-specific antigen (PSA) and shorter PSA doubling time (PSA DT) are associated with a higher ... In a phase-2 multicenter open-label study, 89% of patients with non-metastatic, castration-resistant ... In mice bearing human CRPC xenograft models, apalutamide treatment produced tumor regressions in a dose-dependent …
Matched Categories: … MATE 2 Inhibitors ... MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents …
Durvalumab
Durvalumab is a human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody and a novel immune-checkpoint inhibitor for cancer treatment. Produced by recombinant DNA technology in Chinese Hamster Ovary (CHO) cell suspension culture, durvalumab is a programmed death-ligand 1 (PD-L1) blocking antibody that works to promote normal immune responses that attack tumour...
Approved
Investigational
Matched Description: … Durvalumab is a human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody and a novel immune-checkpoint ... programmed death-ligand 1 (PD-L1) blocking antibody that works to promote normal immune responses that ... locally advanced, unresectable non-small cell lung cancer (NSCLC), only if PD-L1 is expressed in ≥ 1% …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors ... PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors …
Matched Products: … IMFINZI 120 MG/2.4 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET ... IMFINZI 500 MG/10 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors ... PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors …
Matched Products: … IMFINZI 120 MG/2.4 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET ... IMFINZI 500 MG/10 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET …
Sutimlimab
Cold agglutinin disease (CAD) is a type of autoimmune hemolytic anemia (AIHA) in which autoantibodies directed against red blood cell surface antigens cause hemolysis at low (3-4°C) temperatures.[A245154,L40114] This cold subtype accounts for approximately 15-25% of all AIHA and is more common in the elderly.[A245159,L40114] In approximately 90% of cases,...
Approved
Investigational
Matched Synonyms: … Humanized IgG4 monoclonal antibody against total complement component 1, subcomponent s …
Matched Description: … directed against red blood cell surface antigens cause hemolysis at low (3-4°C) temperatures. ... Cold agglutinin disease (CAD) is a type of autoimmune hemolytic anemia (AIHA) in which autoantibodies ... on erythrocytes - these antibodies react optimally at 4°C and are therefore referred to as "cold agglutinin …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Description: … directed against red blood cell surface antigens cause hemolysis at low (3-4°C) temperatures. ... Cold agglutinin disease (CAD) is a type of autoimmune hemolytic anemia (AIHA) in which autoantibodies ... on erythrocytes - these antibodies react optimally at 4°C and are therefore referred to as "cold agglutinin …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Sacituzumab govitecan
Metastatic triple-negative breast cancer (mTNBC) is an aggressive form of breast cancer with limited treatment options involving cytotoxic chemotherapy agents. Targeted chemotherapy through the application of antibody-conjugated agents (ADCs) is a recent advance in cancer treatment. One such ADC is sacituzumab govitecan, which combines a humanized anti-trophoblast cell-surface antigen 2...
Approved
Investigational
Matched Description: … antigen 2 (TROP-2) antibody with the topoisomerase I inhibitor SN-38. ... Commission and Health Canada respectively. ... [A193653] Targeted chemotherapy through the application of antibody-conjugated agents (ADCs) is a recent …
Matched Categories: … Trop-2-Directed Monoclonal Antibodies ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … TRODELVY 200 MG İNFÜZYONLUK ÇÖZELTİ KONSANTRESİ İÇİN TOZ, 1 ADET …
Matched Categories: … Trop-2-Directed Monoclonal Antibodies ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … TRODELVY 200 MG İNFÜZYONLUK ÇÖZELTİ KONSANTRESİ İÇİN TOZ, 1 ADET …
Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated)
Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated) is a vaccine that is used in the prophylaxis of Pertussis (whooping cough), which is caused by a small Gram-negative coccobacillus that infects the mucosal layers of the human respiratory tract.
Approved
Matched Name: … Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated) …
Matched Description: … Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated) is a vaccine that is used ... that infects the mucosal layers of the human respiratory tract. ... in the prophylaxis of Pertussis (whooping cough), which is caused by a small Gram-negative coccobacillus …
Matched Mixtures name: … ADACEL 0,5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 1 ADET ... HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 1 ADET ... HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET …
Matched Description: … Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated) is a vaccine that is used ... that infects the mucosal layers of the human respiratory tract. ... in the prophylaxis of Pertussis (whooping cough), which is caused by a small Gram-negative coccobacillus …
Matched Mixtures name: … ADACEL 0,5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 1 ADET ... HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 1 ADET ... HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET …
Mifamurtide
Mifamurtide is an immunomodulator with antitumor activity via activation of macrophages and monocytes. Also called L-MTP-PE, mifamurtide may be a liposomal form of of the active ingredient MTP-PE, which is a synthetic, less pyrogenic, and longer-acting derivative of muramyl dipeptide (MDP). MDP is a motif present in all gram-positive and...
Approved
Experimental
Matched Iupac: … sodium (2R)-1-({2-[(2S)-2-[(4R)-4-carbamoyl-4-[(2S)-2-[(2R)-2-{[(2R,3R,4R,5R)-2-acetamido-4,5,6-trihydroxy ... -1-oxohexan-3-yl]oxy}propanamido]propanamido]butanamido]propanamido]ethyl phosphono}oxy)-3-(hexadecanoyloxy ... )propan-2-yl hexadecanoate hydrate …
Matched Description: … a synthetic, less pyrogenic, and longer-acting derivative of muramyl dipeptide (MDP). ... first-line therapies, the prognosis is still poor for patients with non-metastatic osteosarcoma with lower 5- ... As a liposomal formulation, mifamurtide demonstrates an enhanced tumoricidal effect and improved safety …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … MEPACT 4 MG INFÜZYONLUK DISPERSIYON KONSANTRESI IÇIN TOZ ,FLAKON, 1 ADET …
Matched Description: … a synthetic, less pyrogenic, and longer-acting derivative of muramyl dipeptide (MDP). ... first-line therapies, the prognosis is still poor for patients with non-metastatic osteosarcoma with lower 5- ... As a liposomal formulation, mifamurtide demonstrates an enhanced tumoricidal effect and improved safety …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … MEPACT 4 MG INFÜZYONLUK DISPERSIYON KONSANTRESI IÇIN TOZ ,FLAKON, 1 ADET …
Anthrax immune globulin human
Anthrax immune globulin is a human antibody given with antibiotics for the treatment of anthrax. It is derived from the plasma of humans immunized with BioThrax (adsorbed anthrax vaccine), which is then further purified. Available as the product Anthrasil (FDA), the result is a solution for slow IV infusion containing...
Approved
Matched Synonyms: … Anthrax immune globulin human ... Anthrax immune globulin (human) ... Anthrax immunoglobulin (human) …
Matched Name: … Anthrax immune globulin human …
Matched Description: … Anthrax immune globulin is a human antibody given with antibiotics for the treatment of anthrax. ... antibodies that bind the protective antigen (PA) component of Bacillus anthracis lethal and edema toxins ... to have direct antibacterial activity against anthrax bacteria, which otherwise may continue to grow and …
Matched Categories: … Human Immunoglobulin ... Amino Acids, Peptides, and Proteins …
Matched Name: … Anthrax immune globulin human …
Matched Description: … Anthrax immune globulin is a human antibody given with antibiotics for the treatment of anthrax. ... antibodies that bind the protective antigen (PA) component of Bacillus anthracis lethal and edema toxins ... to have direct antibacterial activity against anthrax bacteria, which otherwise may continue to grow and …
Matched Categories: … Human Immunoglobulin ... Amino Acids, Peptides, and Proteins …
Talquetamab
Talquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed CD3 T-cell engager. It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each arm comprising a heavy and light chain. Talquetamab binds to GPRC5D, a cell surface...
Approved
Investigational
Matched Synonyms: … 5 MEMBER D)), AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODY ... 5 MEMBER D)), AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODY ... IMMUNOGLOBULIN G4 (233-PROLINE,239-ALANINE,240-ALANINE,410-LEUCINE,414-LYSINE), ANTI-(HUMAN CD3 ANTIGEN …
Matched Description: … Talquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed ... arm comprising a heavy and light chain. ... cells, and CD3 on T cells. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Description: … Talquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed ... arm comprising a heavy and light chain. ... cells, and CD3 on T cells. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Loncastuximab tesirine
Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients who have undergone prior systemic therapies with limited success. Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases and improve survival. On April 23 2021, the Food and Drug Administration granted accelerated...
Approved
Investigational
Matched Synonyms: … A protease cleavable valine-alanine linker ... Humanized monoclonal immunoglobulin G1 antibody directed against human CD19 conjugated to SG3199 through …
Matched Description: … Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients ... refractory B-cell lymphoma is based on promising results from the LOTIS-2 clinical trial. ... and improve survival. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... P-glycoprotein substrates …
Matched Description: … Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients ... refractory B-cell lymphoma is based on promising results from the LOTIS-2 clinical trial. ... and improve survival. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... P-glycoprotein substrates …
Displaying drugs 26 - 50 of 192 in total