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Displaying drugs 26 - 50 of 14490 in total
Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
Approved
Matched Synonyms: … N,N'-Bis(2,3-dihydroxypropyl)-5-(N-(2,3-dihydroxypropyl)acetamido)-2,4,6-triiodoisophthalamide …
Matched Iupac: … N1,N3-bis(2,3-dihydroxypropyl)-5-[N-(2,3-dihydroxypropyl)acetamido]-2,4,6-triiodobenzene-1,3-dicarboxamide …
Matched Description: … Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality. ... water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and
Haemophilus influenzae type b strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen is an active immunization as a booster dose given intramuscularly to pediatric patients who have received a primary series with a Haemophilus b Conjugate Vaccine that is licensed for primarly immunization. The vaccine contains Haemophilus b capsular polysaccharide...
Approved
Investigational
Matched Synonyms: … Haemophilus influenzae type B-PRP and tetanus toxoid conjugate (PRP-T) …
Matched Description: … These are heat inactivated and purified. …
Thrombotic thrombocytopenic purpura (TTP) is a rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and various degrees of organ damage. It may be inherited (congenital TTP; cTTP) or acquired due to autoantibodies (immune-mediated TTP; iTTP), although cTTP accounts for <5% of all cases of TTP. Patients with cTTP...
Approved
Investigational
Matched Synonyms: … Recombinant disintegrin and metalloprotease with thrombospondin type 1 motifs …
Matched Description: … rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and ... Patients with cTTP have a severe deficiency of a plasma metalloproteinase called ADAMTS13 (a disintegrin and ... thrombospondin type 1 motif, member 13), which is responsible for cleaving large von Willebrand factor multimers and
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... apadamtase alfa and cinaxadamtase alfa …
Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.
Approved
Matched Synonyms: … 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine …
Matched Iupac: … 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine …
Matched Description: … peripheral origin, and as an adjuvant in the therapy of epilepsy. ... Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 ... effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and
Matched Categories: … Calcium-Regulating Hormones and Agents …
A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Approved
Matched Synonyms: … 4-(p-bis(beta-chloroethyl)aminophenyl)butyric acid ... 4-(p-bis(β-chloroethyl)aminophenyl)butyric acid ... 4-[p-[bis(2-chloroethyl)amino]phenyl]butyric acid …
Matched Iupac: … 4-{4-[bis(2-chloroethyl)amino]phenyl}butanoic acid …
Matched Description: … nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin...
Approved
Investigational
Matched Synonyms: … 2-amino-N,N'-bis(hexadecahydro-2,5,9-trimethyl-6,13-bis(1-methylethyl)-1,4,7,11,14-pentaoxo-1H-pyrrolo ... -1,2-PYRROLIDINEDIYLCARBONYL(METHYLIMINO)METHYLENECARBONYL))BIS(N-METHYL-L-VALINE) DILACTONE ... 3H-PHENOXAZINE-1,9-DICARBOXAMIDE, 2-AMINO-N,N'-BIS(HEXADECAHYDRO-6,13-DIISOPROPYL-2,5,9-TRIMETHYL-1,4,7,11,14 …
Matched Iupac: … N1,N9-bis[(6S,9R,10S,13R,18aS)-2,5,9-trimethyl-1,4,7,11,14-pentaoxo-6,13-bis(propan-2-yl)-hexadecahydro …
Matched Description: … It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797)
Approved
Withdrawn
Matched Synonyms: … bis(2-hydroxy-3,5,6-trichlorophenyl)methane ... bis(3,5,6-trichloro-2-hydroxyphenyl)methane …
Matched Description: … It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders …
Matched Categories: … Phenol and Derivatives ... Antiseptics and Disinfectants …
Skim milk allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Bos taurus milk, fat removed …
Gibberella fujikuroi allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, fusarium moniliforme …
A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms...
Approved
Matched Synonyms: … bis(diethylthiocarbamoyl) disulfide …
Matched Description: … increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and
Matched Categories: … Scabicides, Insecticides and Repellents ... Antiparasitic Products, Insecticides and Repellents …
Ombitasvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Investigational
Matched Synonyms: … dimethyl ([(2S,5S)-1-(4-tert-butylphenyl)pyrrolidine-2,5-diyl]bis{(4,1-phenylene)carbamoyl(2S)pyrrolidine …
Matched Description: … FDA- and Health Canada-approved product Technivie. ... categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and ... Ombitasvir is an inhibitor of NS5A, a protein essential for viral replication and virion assembly [FDA …
Matched Categories: … Amino Acids, Peptides, and Proteins ... ombitasvir, paritaprevir and ritonavir ... dasabuvir, ombitasvir, paritaprevir and ritonavir …
Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults.[A188309,L10544,L43478] Since 2012, the extended-release formulation has been approved in combination with phentermine for chronic weight management therapy...
Approved
Matched Synonyms: … 2,3:4,5-bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamate …
Matched Description: … Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. ... topiramate from other antiepileptic drugs are a monosaccharide chemical structure containing a sulfamate, and
Matched Categories: … Alimentary Tract and Metabolism ... phentermine and topiramate …
Tigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil. It was developed in response to the growing prevalence of antibiotic resistance in bacteria such as Staphylococcus aureus. It was granted fast-track approval by the U.S. Food and Drug Administration (FDA) on June 17, 2005.
Approved
Matched Synonyms: … (4S,4aS,5aR,12aS)-9-(2-(tert-butylamino)acetamido)-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro …
Matched Iupac: … (4S,4aS,5aR,12aS)-9-[2-(tert-butylamino)acetamido]-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11 …
Matched Description: … Food and Drug Administration (FDA) on June 17, 2005. ... Tigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil …
Purslane is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Portulaca Oleracea Flower/leaf/stem Extract …
Dutasteride is an oral synthetic 4-azasteroid commonly marketed under the trade name Avodart. It is a novel dual 5α-reductase inhibitor that works by blocking both isoforms of 5α-reductase enzymes in a potent, selective, and irreversible manner. Type I and II 5α-reductase enzymes convert testosterone into dihydrotestosterone (DHT), a primary hormonal...
Approved
Investigational
Matched Synonyms: … (5α,17β)-N-(2,5-bis(trifluoromethyl)phenyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide …
Matched Iupac: … (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-[2,5-bis(trifluoromethyl)phenyl]-4a,6a-dimethyl-2-oxo-1H,2H,4aH,4bH,5H …
Matched Description: … hormonal mediator that plays a role in the development and enlargement of the prostate gland. ... [A1909] Type I and II 5α-reductase enzymes convert testosterone into dihydrotestosterone (DHT), a primary ... 5α-reductase inhibitor that works by blocking both isoforms of 5α-reductase enzymes in a potent, selective, and
Matched Mixtures name: … Dutasteride and tamsulosin hydrochloride ... Dutasteride and Tamsulosin Hydrochloride ... Dutasteride and tamsulosin hydrochloride …
Matched Categories: … tamsulosin and dutasteride ... Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Pyridoxine is the 4-methanol form of vitamin B6, an important water-soluble vitamin that is naturally present in many foods. As its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required for normal functioning of many biological systems within the body. While many plants and microorganisms are...
Approved
Investigational
Nutraceutical
Vet approved
Matched Synonyms: … 3-hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridine …
Matched Iupac: … 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol …
Matched Description: … and pyridoxamine 5'-phosphate. ... glycogen, the synthesis of nucleic acids, hemogloblin, sphingomyelin and other sphingolipids, and the ... As its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required …
Matched Mixtures name: … Somarexin and C 1000 ... Multi Vitamin and Mineral vitamin ... Multi Vitamin and Fluoride …
Matched Categories: … Diet, Food, and Nutrition ... Alimentary Tract and Metabolism ... isoniazid, sulfamethoxazole, trimethoprim and pyridoxine …
Cisatracurium is a non-depolarising neuromuscular blocking agent of the benzylisoquinolinium class, available in its salt form, cisatracurium besylate.[A243416,A253592] Cisatracurium has an intermediate duration of action and is one of the most commonly used neuromuscular blocking agents in intensive care.[A253592,A253597]. Cisatracurium acts on cholinergic receptors, blocking neuromuscular transmission. This action is...
Approved
Investigational
Matched Synonyms: … (1r,2r,1'r,2'r)-2,2'-{pentane-1,5-diylbis[oxy(3-oxopropane-3,1-diyl)]}bis[1-(3,4-dimethoxybenzyl)-6,7 …
Matched Description: … [A243416,A253592] Cisatracurium has an intermediate duration of action and is one of the most commonly ... [A243416,A253592] Cisatracurium is an R-cis-R-cis isomer of [atracurium] and has approximately 3 times …
Technetium Tc 99m Mebrofenin is a diagnostic radiopharmaceutical composed of diisopropyl-iminodiacetic acid (DISIDA) attached to a technetium-99m ion. Following intravenous injection, single photon emission computer tomography (SPECT) imaging of the liver or gallbladder is performed using a gamma camera to detect the gamma rays emitted by the technetium-99m as it...
Approved
Matched Synonyms: … Bis(2-[[2-(3-bromo-2,4,6-trimethylanilino)-2-oxoethyl]-(carboxymethyl)amino]acetate) technetium …
Matched Description: … uptake and fast biliary excretion, resulting in improved hepatic imaging. ... More specifically, mebrofenin is taken up into hepatocytes through the action of OATP1B1 and OATP1B3 ... Currently available within a sterile kit, Tc-99m Mebrofenin is indicated for imaging of the liver and
Matched Categories: … Indicators and Reagents ... Amino Acids, Peptides, and Proteins ... Hepatic and Reticulo Endothelial System …
A depressor amine derived by enzymatic decarboxylation of histidine. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
Approved
Investigational
Matched Description: … a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and
Matched Mixtures name: … Histamine DHCl 0.10 Percent and Menthol 2 Percent …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … MINTED LEAF Odorless Histamine DHCl Pain Relief and Hemp Extract ... Minted Leaf Odorless Pain Relief ... Hand and Wrist Pain Cream …
A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae. Its mechanism of action is probably similar to that of the sulfonamides which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with pyrimethamine in the treatment of...
Approved
Investigational
Matched Synonyms: … bis(4-aminophenyl)sulfone ... Bis(p-aminophenyl) sulfone …
Matched Categories: … dapsone and rifampicin ... dapsone, rifampicin and clofazimine …
Ethambutol is a bacteriostatic agent indicated alongside medications such as isoniazid, rifampin, and pyrazinamide in the treatment of pulmonary tuberculosis. Ethambutol was first described in the literature in 1961. It was developed out of a need for therapies active against isoniazid resistant strains of Mycobacterium tuberculosis. Ethambutol was granted FDA...
Approved
Matched Synonyms: … (+)-N,N'-bis(1-(hydroxymethyl)propyl)ethylenediamine …
Matched Description: … Ethambutol is a bacteriostatic agent indicated alongside medications such as [isoniazid], [rifampin], and
Matched Categories: … ethambutol and isoniazid ... rifampicin, ethambutol and isoniazid ... rifampicin, pyrazinamide, ethambutol and isoniazid …
Mucor circinelloides f. circinelloides allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, mucor circinelloides f. circinelloides …
A chelating agent (chelating agents) that sequesters a variety of polyvalent cations. It is used in pharmaceutical manufacturing and as a food additive.
Approved
Vet approved
Matched Synonyms: … {[-(bis-carboxymethyl-amino)-ethyl]-carboxymethyl-amino}-acetic acid …
Matched Iupac: … 2-({2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetic acid …
Matched Description: … It is used in pharmaceutical manufacturing and as a food additive. …
Matched Categories: … Diet, Food, and Nutrition …
Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements. Capsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical formulations. The most recent...
Approved
Matched Description: … Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, ... and patch preparations of various strengths; however, it may also be found in some dietary supplements …
Matched Mixtures name: … Satohap Cool and Hot Pads ... Zostrix Hot and Cold Therapy System ... Cajun Hot Ice Muscle and Joint Pain Rub …
Matched Categories: … Basic Lotions and Liniments ... Capsaicin and Similar Agents ... Topical Products for Joint and Muscular Pain …
Matched Products: … MINTED LEAF Heat Therapy Roll-On with Capsaicin and CBD ... Minted Leaf Heat Therapy Relief Roll-On ... MINTED LEAF Heat Therapy Relief Roll On …
A nonfluorinated corticosteroid anti-inflammatory agent used topically for dermatoses.
Approved
Investigational
Matched Synonyms: … 11β,21-dihydroxy-16α,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione …
Matched Categories: … desonide and antiseptics …
Displaying drugs 26 - 50 of 14490 in total