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Displaying drugs 476 - 500 of 973 in total
Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced by recombinant DNA technology in a Pichia pastoris expression system. Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. Agent for pharmacologic vitreolysis; thrombolytic agent. FDA approved...
Approved
Matched Synonyms: … Microplasmin (synthetic human) ... Recombinant human microplasmin …
Matched Description: … Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. ... Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … Recombinant human IgG1 Fc multimer ... Recombinant Multimerized Human IgG1 Fc …
Prothrombin Complex Concentrate (Human), is indicated for the urgent reversal of acquired coagulation factor deficiency induced by Vitamin K antagonist (VKA, e.g., warfarin) therapy in adult patients with acute major bleeding.
Approved
Matched Synonyms: … Coagulation factor II human ... Coagulation factor II (human) ... Human coagulation factor II …
Matched Description: … Prothrombin Complex Concentrate (Human), is indicated for the urgent reversal of acquired coagulation ... factor deficiency induced by Vitamin K antagonist (VKA, e.g., warfarin) therapy in adult patients with …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU ... Octaplex Powder and Solvent for Solution for Infusion …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Experimental
Matched Name: … Nz-(1-Carboxyethyl)-Lysine
Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.[L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493] The first ciprofloxacin containing product was FDA approved on 22 October 1987.
Approved
Investigational
Matched Description: … [A178870] It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration …
Matched Mixtures name: … Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Fluocinolone Acetonide …
Matched Categories: … ciprofloxacin and tinidazole ... ciprofloxacin and ornidazole ... ciprofloxacin and metronidazole ... Drug-Related Side Effects and Adverse Reactions ... Ophthalmological and Otological Preparations …
Matched Products: … Ciprofloxacin and Dextrose ... CILOXAN STERILE OPHTHALMIC AND OTIC SOLUTION 0.3% …
Albusomatropin has been used in trials studying the treatment of Growth Hormone-Deficiency and Growth Hormone Deficiency.
Investigational
Matched Synonyms: … recombinant human serum albumin human growth hormone ... RECOMBINANT HUMAN ALBUMIN-RECOMBINANT HUMAN GROWTH HORMONE FUSION PROTEIN ... HUMAN SERUM ALBUMIN FUSED TO THE N-TERMINUS OF GROWTH HORMONE …
Matched Description: … Albusomatropin has been used in trials studying the treatment of Growth Hormone-Deficiency and Growth …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Plasma gelsolin (pGSN) is a protein found in the blood of healthy individuals which scavenges compounds left over from damaged tissues.
Investigational
Matched Synonyms: … Recombinant human gelsolin …
Matched Name: … Recombinant human plasma gelsolin …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intracellular Signaling Peptides and Proteins …
Coagulation Factor X (Human), is a plasma-derived human blood coagulation factor is used by adults and children (aged 12 years and above) with hereditary Factor X deficiency. However its use is limited in the perioperative setting for the management of bleeding in major surgery in patients with moderate and severe...
Approved
Investigational
Matched Synonyms: … Coagulation factor X (human) ... Human coagulation factor X …
Matched Name: … Coagulation factor X human
Matched Description: … Coagulation Factor X (Human), is a plasma-derived human blood coagulation factor is used by adults and ... with moderate and severe hereditary Factor X deficiency. ... children (aged 12 years and above) with hereditary Factor X deficiency. …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU ... Octaplex Powder and Solvent for Solution for Infusion …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Blood and Blood Forming Organs …
Investigational
Matched Synonyms: … Human IL-15 …
Matched Name: … Interleukin-15, human recombinant …
Investigational
Matched Name: … Recombinant Factor XIII (human) …
Investigational
Matched Synonyms: … Recombinant soluble CD4 (human) …
Matched Name: … Recombinant soluble human CD4 …
Investigational
Matched Name: … Human glial progenitor cells …
Protein C is an endogenously occurring plasma protein that plays a key role within the coagulation cascade. Protein C is a zymogen, or enzyme precursor, of a vitamin K-dependent anticoagulant glycoprotein (serine protease) that is synthesized in the liver. It is converted by the thrombin/thrombomodulin-complex on the endothelial cell surface...
Approved
Matched Synonyms: … Human protein C ... Protein C human ... Protein C concentrate human
Matched Description: … adult patients with severe congenital protein C deficiency for the prevention and treatment of venous ... thrombosis and purpura fulminans. ... VIII), which leads to a decrease in thrombin formation, and therefore a reduction in clot formation. …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU ... Octaplex Powder and Solvent for Solution for Infusion …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Plasminogen is a pro-enzyme (i.e. a zymogen) which is cleaved to form plasmin - also known as fibrinolysin - as part of the fibrinolytic pathway that breaks down fibrin blood clots. This pathway is activated when a clot is no longer needed or to prevent a clot from extending beyond...
Approved
Matched Synonyms: … Human plasminogen ... plasminogen, human-tvmh …
Matched Description: … [L34615] It is the first and only FDA-approved treatment for this condition, which causes wood-like lesions ... to form on the mucous membranes of patients, providing an unmet medical need for patients with this ... [L34635] In June 2021, the FDA approved a plasma-derived plasminogen (Ryplazim, human plasminogen-tvmh …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Netakimab is under investigation in clinical trial NCT03447704 (International Multicenter Comparative Randomized Placebo-controlled Clinical Study of Efficacy and Safety of BCD-085 in Patients With Ankylosing Spondylitis).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human interleukin 17) (human-lama glama monoclonal heavy chain), disulfide with ... human monoclonal light chain, dimer …
Matched Description: … NCT03447704 (International Multicenter Comparative Randomized Placebo-controlled Clinical Study of Efficacy and ... Safety of BCD-085 in Patients With Ankylosing Spondylitis). …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
rhMBL is a protein therapeutic being developed by Enzon for the prevention and treatment of severe infections in individuals with low levels of Mannose-Binding Lectin (MBL). Over 10 percent of the general population is estimated to be MBL-deficient. Natural MBL is a 400-700kDa oligomer made of 3 identical 32kDa peptide...
Investigational
Matched Synonyms: … Recombinant human mannan-binding protein ... Recombinant human mannose-binding lectin …
Matched Description: … rhMBL is a protein therapeutic being developed by Enzon for the prevention and treatment of severe infections …
C-peptide is under investigation in clinical trial NCT00278980 (Effect of C-peptide on Diabetic Peripheral Neuropathy).
Investigational
Matched Synonyms: … Human c-peptide ... Human proinsulin c-peptide ... Proinsulin c-peptide (human) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Palucorcel is an investigational stem cell therapy consisting of human umbilical tissue-derived cells. Developed by Janssen Biotech, it is being investigated for the treatment of various conditions such as amyotrophic lateral sclerosis (ALS) and macular degeneration.
Investigational
Matched Synonyms: … Human umbilical tissue-derived cells ... HUMAN UMBILICAL TISSUE-DERIVED CELLS (ALLOGENIC) …
Matched Description: … being investigated for the treatment of various conditions such as amyotrophic lateral sclerosis (ALS) and ... Palucorcel is an investigational stem cell therapy consisting of human umbilical tissue-derived cells …
Investigational
Matched Synonyms: … Immunoglobulin igg4, anti-(human cd47) (human monoclonal srf231 .gamma.4-chain), disulfide with human
Investigational
Matched Synonyms: … Human heterologous liver cells ... Heterologous human adult liver derived progenitor cells …
Matched Name: … Heterologous human adult liver derived progenitor cells …
Investigational
Matched Synonyms: … Recombinant human alpha 1-antitrypsin ... Recombinant human alpha 1-antitrypsin (raat) …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Human Lactoferrin Peptide hLF1-11 is under investigation in clinical trial NCT00509834 (A Study on the Tolerability and Early Efficacy of Hlf1-11 in Patients With Proven Candidaemia).
Investigational
Matched Synonyms: … Human lactoferrin 1-11 ... N-terminal peptide of human lactoferrin 1-11 …
Matched Name: … Human Lactoferrin Peptide hLF1-11 …
Matched Description: … Tolerability and Early Efficacy of Hlf1-11 in Patients With Proven Candidaemia). ... Human Lactoferrin Peptide hLF1-11 is under investigation in clinical trial NCT00509834 (A Study on the …
Mapatumumab is under investigation in clinical trial NCT00094848 (Study of TRM-1 (TRAIL-R1 Monoclonal Antibody) in Subjects With Relapsed or Refractory Non-hodgkin's Lymphoma (NHL)).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human trail-r1) (human monoclonal trm-1 heavy chain), disulfide with human monoclonal ... Immunoglobulin g1, anti-(human cytokine receptor dr4 (death receceptor 4)) (human monoclonal trm-1 heavy ... Immunoglobulin g1, anti-(human cytokine receptor dr4 (death receceptor 4)) (human monoclonal trm-1 heavy …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Brazikumab is under investigation in clinical trial NCT03759288 (An Active and Placebo-controlled Study of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease).
Investigational
Matched Synonyms: … Immunoglobulin g2, anti-(human interleukin 23) (human monoclonal medi2070 heavy chain), disulfide with ... human monoclonal medi2070 .lambda. …
Matched Description: … Brazikumab is under investigation in clinical trial NCT03759288 (An Active and Placebo-controlled Study …
Human vaccinia immune globulin (VIG) is a sterile solution containing the purified gamma globulin (IgG) fraction of plasma taken from healthy donors previously vaccinated with live vaccinia virus vaccine who possess high titers of anti-vaccinia virus antibody [FDA Label, A33814]. The IgG fraction is purified by the anion-exchange column chromatography...
Approved
Matched Synonyms: … Human vaccinia immune globulin ... Vaccinia Immune Globulin (Human) Intravenous ... Vaccinia immune globulin intravenous (human) …
Matched Name: … Human vaccinia virus immune globulin …
Matched Description: … Nevertheless, VIG by virtue of the way it is produced is a poorly characterized and highly variable human ... The IgG fraction is purified by the anion-exchange column chromatography method and the solution is solvent ... is only available in very limited quantities - all factors that may intervene with its availability and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Human Immunoglobulin G …
Displaying drugs 476 - 500 of 973 in total