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Displaying drugs 476 - 500 of 1252 in total
Drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and penicillin-resistant Streptococcus penumoniae, represent a massive public health threat.[A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the previously approved linezolid and is generally effective against multidrug-resistant Gram-positive bacteria. Tedizolid is indicated for the...
Approved
Matched Synonyms: … Tedizolid phosphate ... Torezolid phosphate ... fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl]methyl dihydrogen phosphate
Matched Name: … Tedizolid phosphate
Matched Description: … Tedizolid was approved by the FDA on June 20, 2014, for sale by Cubist Pharmaceuticals as tedizolid phosphate ... ) and is generally more effective and more tolerable than [linezolid]. ... such as methicillin-resistant _Staphylococcus aureus_, vancomycin-resistant _Enterococcus faecium_, and
Fexofenadine is an over-the-counter second-generation antihistamine used in the treatment of various allergic symptoms. It is selective for the H1 receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier - this is in contrast to previous first-generation antihistamines, such as diphenhydramine, which readily bind to off-targets...
Approved
Investigational
Matched Description: … L4269] It is selective for the H1 receptor, carries little-to-no activity at off-targets, and ... [A1452] Fexofenadine is the major active metabolite of [terfenadine][A1495] and is administered as a …
Matched Mixtures name: … FEXOFENADINE HCl AND PSEUDOEPHEDRINE HCl ... FEXOFENADINE HYDROCHLORIDE and PSEUDOEPHEDRINE HYDROCHLORIDE ... Allegra D 12 Hour Allergy and Congestion …
Matched Products: … Up and Up Allergy Relief ... Berkley and Jensen Allergy Relief ... Up and Up Non Drowsy Allergy Relief …
Phenytoin is classified as a hydantoin derivative and despite its narrow therapeutic index, it is one of the most commonly used anticonvulsants.[A33595,A188832,A189219] Since it's introduction about 80 years ago, phenytoin has not only been established as an effective anti-epileptic, but has also been investigated for several other indications such as...
Approved
Vet approved
Matched Description: … Phenytoin is classified as a hydantoin derivative and despite its narrow therapeutic index, it is one ... has also been investigated for several other indications such as bipolar disorder, retina protection, and ... [A189219,A35884] Both parenteral and oral formulations of phenytoin are available on the market. …
Matched Salts name: … Phenytoin sodium
Matched Categories: … Phenytoin and Prodrugs ... Metabolic Side Effects of Drugs and Substances ... Sodium Channel Blockers ... Voltage-Gated Sodium Channel Blockers ... Medications that reduce magnesium levels …
Matched Products: … Phenytoin Sodium ... PHENYTOIN SODIUM ... Extended Phenytoin Sodium
Approved
Matched Name: … Sodium phosphate, monobasic, unspecified form …
Matched Mixtures name: … TERUFLEX Blood Bag System with Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) AND ... TERUFLEX Blood Bag System Anticoagulant Citrate Phosphate Dextrose (CPD) AND OPTISOL Red Cell Preservative ... Phosphate
Experimental
Matched Synonyms: … Xylitol 5-phosphate
Matched Name: … L-xylitol 5-phosphate
Matched Categories: … Sugar Phosphates
Potassium is the major cation (positive ion) inside animal cells, while sodium is the major cation outside animal cells. The concentration differences of these charged particles causes a difference in electric potential between the inside and outside of cells, known as the membrane potential. The balance between potassium and sodium...
Approved
Investigational
Matched Synonyms: … Potassium (ion) ... Potassium ion ... potassium(1+) …
Matched Name: … Potassium cation …
Matched Iupac: … potassium(1+) ion …
Matched Description: … The balance between potassium and sodium is maintained by ion pumps in the cell membrane. ... The cell membrane potential created by potassium and sodium ions allows the cell generate an action potential—a ... Potassium is the major cation (positive ion) inside animal cells, while sodium is the major cation outside …
Matched Categories: … Potassium Salt …
Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Synonyms: … PEPTIDE PRODUCED IN ESCHERICHIA COLI, AN AVERAGE OF 13 RESIDUES ARE SUBSTITUTED ON N.ALPHA..1ALANINE AND ... 356)-PEPTIDE, PRODUCED IN ESCHERICHIA COLI, SUBSTITUTED ON N2 OF THE N-TERMINAL ALANYL RESIDUE (A1) AND
Matched Description: … as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and ... with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues ... [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Antineoplastic and Immunomodulating Agents …
Aluminum zirconium tetrachlorohydrex gly is a common active ingredient in personal care products as an antiperspirant agent. Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing sweat from leaving the body.
Approved
Matched Description: … Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing …
Matched Products: … Ap 22% (regular,sport,musk and Unscented) ... Mitchum Clear Gel A.P. and Deod.supersport ... Body Satin Antiperspirant and Deodorant …
Experimental
Matched Synonyms: … β-D-glucose 6-phosphate ... beta-D-glucose-6-phosphate ... beta-D-glucose 6-(dihydrogen phosphate) …
Matched Name: … beta-D-glucose 6-phosphate
Investigational
Matched Synonyms: … or 17,18)-dihydro-21h,23h-porphine-5,10-diyl)bisbenzenesulfonic acid, mixture of three isomers a, b and
RP-L102 is a lentiviral vector carrying the Fanconi Anemia-A (FANCA) gene currently being developed by Rocket Pharmaceuticals for the treatment of Fanconi anemia type A
Investigational
Matched Synonyms: … Autologous CD34+-enriched Hematopoietic Stem and Progenitor Cells Transduced with Lentiviral Vector Carrying …
Investigational
Matched Synonyms: … CYCLIZED P12 (PEPTIDE BOND BETWEEN THE CARBOXY AND AMINO-TERMINAL ENDS OF THE LINEAR PEPTIDE PSHISKYILRWRPK …
Guaiacolsulfonate is an aromatic sulfonic acid. Potassium guaiacolsulfonate salt is an expectorant that thins the mucus in the lungs and reduces chest congestion.
Approved
Experimental
Matched Synonyms: … Guaiacolsulfonate potassium ... Potassium sulfoguaiacolate …
Matched Name: … Potassium guaiacolsulfonate …
Matched Description: … Potassium guaiacolsulfonate salt is an expectorant that thins the mucus in the lungs and reduces chest …
Matched Mixtures name: … Phenylephrine Carbetapentane Potassium Guaiacolsulfonate …
Matched Categories: … Potassium Salt …
Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmune disorders. Betamethasone has potent glucocorticoid activity and negligible mineralocorticoid activity.
Approved
Vet approved
Matched Description: … Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. ... [A192444] It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally ... [A192444] Betamethasone has potent glucocorticoid activity and negligible mineralocorticoid activity. …
Matched Mixtures name: … Betamethasone Sodium Phosphate and Betamethasone Acetate ... Betamethasone Sodium Phosphate and Betamethasone Acetate ... Betamethasone Sodium Phosphate and Betamethasone Acetate …
Matched Salts name: … Betamethasone sodium phosphate
Matched Categories: … Medications that reduce magnesium levels ... Alimentary Tract and Metabolism ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Sex Hormones and Insulins ... betamethasone and mydriatics …
Matched Products: … Betnesol Eye and Ear Drops ... Betnesol Eye and Ear Drops 0.1% ... SODERM CREME …
Pacmilimab is under investigation in clinical trial NCT04596150 (Study to Evaluate the Safety and Antitumor Activity of CX-2009 Monotherapy and in Combination With CX-072 in Advanced Breast Cancer).
Investigational
Matched Synonyms: … HUMAN MONOCLONAL CX-072 .GAMMA.4-CHAIN), DISULFIDE WITH PRODOMAIN PROTEIN (SYNTHETIC MASKING MOIETY AND
Matched Description: … Pacmilimab is under investigation in clinical trial NCT04596150 (Study to Evaluate the Safety and Antitumor ... Activity of CX-2009 Monotherapy and in Combination With CX-072 in Advanced Breast Cancer). …
C-CAR039 is an autologous Chimeric Antigen Receptors (CAR) T-cell therapy expressing CD19/CD20 bi-specific CAR.
Investigational
Matched Synonyms: … , non-replicating lentiviral vector, encoding a bispecific chimeric antigen receptor targeting CD19 and
Experimental
Matched Synonyms: … α-D-mannose 6-phosphate ... alpha-D-Mannopyranose 6-phosphate
Matched Name: … alpha-D-mannose 6-phosphate
Experimental
Matched Synonyms: … Calcium diethyl difumarate ... Calcium monoethyl fumarate …
Matched Name: … Calcium monoethylfumarate …
Matched Iupac: … calcium bis((2E)-4-ethoxy-4-oxobut-2-enoate) …
A bismuth compound used for peptic ulcer and gastro-oesophageal reflux disease (GORD).
Approved
Investigational
Matched Synonyms: … Bismuth subcitrate potassium anhydrous
Matched Name: … Bismuth subcitrate potassium
Matched Description: … A bismuth compound used for peptic ulcer and gastro-oesophageal reflux disease (GORD). …
Matched Mixtures name: … Bismuth Subcitrate Potassium, Metronidazole and Tetracycline Hydrochloride ... Bismuth Subcitrate Potassium, Metronidazole, and Tetracycline Hydrochloride ... Bismuth subcitrate potassium, Metronidazole, Tetracycline hydrochloride …
Matched Salts name: … Bismuth subcitrate potassium monohydrate …
Matched Categories: … Alimentary Tract and Metabolism ... bismuth subcitrate, tetracycline and metronidazole ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Experimental
Matched Synonyms: … Erythose-4-phosphate
Matched Name: … D-erythrose 4-phosphate
Experimental
Matched Synonyms: … Calcium (2+) ... Calcium ions ... calcium(2+) ion …
Matched Name: … Calcium cation …
Matched Iupac: … calcium(2+) ion …
Matched Categories: … Phosphate Binder ... Calcium Salts …
Pectin is a heteropolysaccharide commercially derived from the cell wall of higher plants. It is composed of partially methylated polygalacturonic acid units linked in the positions 1-4. The carboxylic group of the constituents of pectin can exist in the form of esters, free acids, ammonium, potassium or sodium salts or...
Approved
Investigational
Vet approved
Matched Description: … or sodium salts or as acid amides. ... carboxylic group of the constituents of pectin can exist in the form of esters, free acids, ammonium, potassium
Matched Mixtures name: … Cepacol Sore Throat and Coating ... Kaolin and Pectin Susp ... Sucrets Complete Sore Throat, Cough and Irritation …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Matched Products: … Ludens Honey and Berry …
Approved
Matched Synonyms: … Cromato sodico (51 Cr) ... Chromate (51 Cr) de sodium ... Sodium chromate (51 Cr) …
Matched Name: … Sodium chromate Cr-51 …
Matched Products: … Chromitope Sodium ... SODIUM CHROMATE (51CR) SOLUTION BP* …
A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Approved
Investigational
Matched Description: … It inhibits gastric acid secretion, as well as pepsin and gastrins output. …
Matched Categories: … Alimentary Tract and Metabolism ... Metabolic Side Effects of Drugs and Substances ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) ... Medications that reduce magnesium levels …
Matched Products: … Cimetidine in Sodium Chloride ... Up and Up Acid Reducer …
Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Investigational
Matched Description: … acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and
Matched Mixtures name: … Actonel With Calcium ... Actonel With Calcium ... Actonel with Calcium
Matched Salts name: … Risedronate sodium ... Risedronate sodium monohydrate ... Risedronate sodium hemi-pentahydrate …
Matched Categories: … Calcium-Regulating Hormones and Agents ... risedronic acid and calcium, sequential ... risedronic acid, calcium and colecalciferol, sequential ... Drugs Affecting Bone Structure and Mineralization ... risedronic acid and colecalciferol …
Matched Products: … ACTONEL PLUS CALCIUM 35MG ... Risedronate Sodium ... Risedronate Sodium Amorphous Fv2910cl …
Displaying drugs 476 - 500 of 1252 in total