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Displaying drugs 5001 - 5025 of 5846 in total
Investigational
Matched Synonyms: … N-(3-(2-(2,3-difluoro-4-(4-(2-hydroxyethyl)piperazin-1-yl)phenylamino)quinazolin-8-yl)phenyl)acrylamide …
Investigational
Matched Synonyms: … immunoglobulin gamma-1 with kappa light chains, IgG1kappa) directed against human soluble cytokine interferon beta
Anisotropine methylbromide is a quaternary ammonium compound. Its use as treatment adjunct in peptic ulcer has been replaced by the use of more effective agents. Depending on the dose, anisotropine methylbromide may reduce the motility and secretory activity of the gastrointestinal system, and the tone of the ureter and urinary...
Approved
Matched Synonyms: … 8-Methyl-3-(2-propylpentanoyloxy)tropinium bromide ... endo-8,8-Dimethyl-3-((1-oxo-2-propylpentyl)oxy)-8-azoniabicyclo(3.2.1)octane bromide …
Matched Iupac: … 8,8-dimethyl-3-[(2-propylpentanoyl)oxy]-8-azabicyclo[3.2.1]octan-8-ium bromide …
Matched Description: … gastric acid secretion. ... gastrointestinal system, and the tone of the ureter and urinary bladder and may have a slight relaxant ... , and accommodation; cause dilatation of the pupil; and increase the heart rate. …
Fimepinostat (CUDC-907) has been used in trials studying the treatment of lymphoma, solid tumors, breast cancer, multiple myeloma, and NUT midline carcinoma, among others.
Investigational
Matched Synonyms: … 5-pyrimidinecarboxamide, N-hydroxy-2-[[[2-(6-methoxy-3-pyridinyl)-4-(4-morpholinyl)thieno[3,2-d]pyrimidin ... N-hydroxy-2-(((2-(6-methoxypyridin-3-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)(methyl)amino …
Matched Iupac: … N-hydroxy-2-({[2-(6-methoxypyridin-3-yl)-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl}(methyl …
Matched Description: … been used in trials studying the treatment of lymphoma, solid tumors, breast cancer, multiple myeloma, and
Matched Salts cas: … 1401998-36-4 …
Matched Categories: … Phosphatidylinositol 3-Kinases, antagonists & inhibitors …
Ceftaroline fosamil is a cephalosporin antibacterial indicated for the treatment of the following infections caused by designated susceptible bacteria: Acute bacterial skin and skin structure infections. Community-acquired bacterial pneumonia.
Approved
Investigational
Matched Synonyms: … (6R,7R)-7-[(2Z)-2-ethoxyimino-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-3-[4-(1-methylpyridin …
Matched Iupac: … ]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]sulfanyl}-1,3-thiazol-4-yl)-1-methylpyridin-1-ium ... 4-(2-{[(6R,7R)-2-carboxylato-7-[(2Z)-2-(ethoxyimino)-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetamido …
Matched Description: … treatment of the following infections caused by designated susceptible bacteria: Acute bacterial skin and
Matched Salts name: … Ceftaroline fosamil acetate ... Ceftaroline fosamil acetate monohydrate …
Matched Categories: … Thiazines ... beta-Lactams ... beta Lactam Antibiotics …
Experimental
Matched Synonyms: … 3-Acetoacetyl-CoA …
Matched Iupac: … ]oxy}methyl)oxolan-3-yl]oxy}phosphonic acid ... {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-2,2-dimethyl ... -3-{[2-({2-[(3-oxobutanoyl)sulfanyl]ethyl}carbamoyl)ethyl]carbamoyl}propoxy]phosphoryl}oxy)phosphoryl …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Enzymes and Coenzymes …
Non-methylated, competitive, and irreversible inhibitor of caspase 1, as well as other caspases,1 which can be used directly with purified enzymes. It does not require an esterase to hydrolyze the O-methyl ester like the cell-permeable form, Z-Val-Ala-Asp(O-Me) fluoromethyl ketone.
Experimental
Matched Synonyms: … N-[(Benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxo-2-butanyl]-L-alaninamide …
Matched Iupac: … acid ... (3S)-3-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanamido]propanamido]-5-fluoro-4-oxopentanoic …
Matched Description: … Non-methylated, competitive, and irreversible inhibitor of caspase 1, as well as other caspases,1 which …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids
Investigational
Matched Synonyms: … Pyrazolo(1,5-a)pyrimidine-3-carboxamide, n-(1-ethyl-1-(4-ethylphenyl)propyl)-4,5,6,7-tetrahydro-2,7,7 …
Matched Iupac: … 3-carboxamide ... (5R)-N-[3-(4-ethylphenyl)pentan-3-yl]-2,7,7-trimethyl-5-phenyl-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine- …
Matched Salts cas: … 667931-33-1 …
Matched Categories: … Receptors, Calcium-Sensing, antagonists & inhibitors …
Investigational
Matched Synonyms: … 2-(2-chlorophenyl)-5-hydroxy-8-((3S,4R)-3-hydroxy-1-methylpiperidin-4-yl)-4-oxo-4H-chromen-7-yl dihydrogen ... 4h-1-benzopyran-4-one, 2-(2-chlorophenyl)-5-hydroxy-8-((3s,4r)-3-hydroxy-1-methyl-4-piperidinyl)-7-(phosphonooxy …
Matched Iupac: … }phosphonic acid ... {[2-(2-chlorophenyl)-5-hydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]-4-oxo-4H-chromen-7-yl]oxy …
First synthesized by Janssen Pharmaceuticals in 1955, cinnarizine is an anti-histaminic drug mainly used for the control of vestibular disorders and motion sickness. Cinnarizine is a specific calcium channel blocker that primarily works on the central vestibular system to interfere with the signal transmission between vestibular apparatus of the inner...
Approved
Investigational
Matched Synonyms: … 1-(Diphenylmethyl)-4-(3-phenyl-2-propenyl)piperazine …
Matched Iupac: … 1-(diphenylmethyl)-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine …
Matched Description: … in 1955, cinnarizine is an anti-histaminic drug mainly used for the control of vestibular disorders and ... to interfere with the signal transmission between vestibular apparatus of the inner ear and the vomiting ... Cinnarizine is a specific calcium channel blocker that primarily works on the central vestibular system …
Matched Salts cas: … 25332-14-3
Matched Salts name: … Cinnarizine hydrochloride
Matched Categories: … Calcium-Regulating Hormones and Agents ... Calcium Channel Blockers …
Efinaconazole is a 14 alpha-demethylase inhibitor indicated in the treatment of fungal infection of the nail, known as onychomycosis. It was approved for use in Canada and the USA in 2014 and is marketed by Valeant Pharmaceuticals North America LLC under the name Jublia.
Approved
Matched Synonyms: … (2R,3R)-2-(2,4-Difluorophenyl)-3-(4-methylene-1-piperidinyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol …
Matched Iupac: … (2R,3R)-2-(2,4-difluorophenyl)-3-(4-methylidenepiperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol …
Matched Description: … It was approved for use in Canada and the USA in 2014 and is marketed by Valeant Pharmaceuticals North ... Efinaconazole is a 14 alpha-demethylase inhibitor indicated in the treatment of fungal infection of the …
Matched Categories: … Imidazole and Triazole Derivatives …
Brilaroxazine (RP5063) is an investigational atypical antipsychotic which is under development by Reviva Pharmaceuticals for the treatment of schizophrenia and schizoaffective disorder. Reviva Pharmaceuticals also intends to investigate RP5063 for the treatment of bipolar disorder, major depressive disorder, psychosis/agitation associated with Alzheimer's disease, Parkinson's disease psychosis, attention deficit hyperactivity disorder...
Investigational
Matched Synonyms: … 6-(4-(4-(2,3-Dichlorophenyl)-piperazin-1-yl)-butoxy)-2H-benzo(b)(1,4)oxazin-3(4H)-one …
Matched Iupac: … 6-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydro-2H-1,4-benzoxazin-3-one …
Matched Description: … antipsychotic which is under development by Reviva Pharmaceuticals for the treatment of schizophrenia and ... Alzheimer's disease, Parkinson's disease psychosis, attention deficit hyperactivity disorder (ADD/ADHD), and
Matched Salts name: … Brilaroxazine hydrochloride
Entrectinib is a tropomyosin receptor tyrosine kinase (TRK) TRKA, TRKB, TRKC, proto-oncogene tyrosine-protein kinase ROS1, and anaplastic lymphoma kinase (ALK) inhibitor. It was approved by the FDA in August 2019 for use in the treatment of ROS1-positive metastatic non-small cell lung cancer and NTRK gene fusion positive solid tumors. Entrectinib's...
Approved
Investigational
Matched Synonyms: … N-[5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl]-4-(4-methylpiperazin-1-yl)-2-(oxan-4-ylamino)benzamide …
Matched Iupac: … N-{5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl}-4-(4-methylpiperazin-1-yl)-2-[(oxan-4-yl)amino]benzamide …
Matched Description: … kinase ROS1, and anaplastic lymphoma kinase (ALK) inhibitor. ... FDA in August 2019 for use in the treatment of ROS1-positive metastatic non-small cell lung cancer and ... This therapy offers benefit over similar ALK inhibitors such as [alectinib], [ceritinib], and [lorlatinib …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Protein Kinase Inhibitors …
Matched Products: … ROZLYTREK 100 MG SERT KAPSÜL , 30 ADET …
4'-Thio-fac is under investigation in clinical trial NCT02661542 (Study of FF-10502-01 in Patients With Advanced Solid Tumors and Lymphomas).
Investigational
Matched Synonyms: … 4-Amino-1-[(2R,3S,4S,5R)-3-Fluoro-4-Hydroxy-5-(Hydroxymethyl)Tetrahydrothiophen-2-Yl] Pyrimidin-2(1H) …
Matched Iupac: … 4-amino-1-[(2R,3S,4S,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)thiolan-2-yl]-1,2-dihydropyrimidin-2-one …
Matched Description: … investigation in clinical trial NCT02661542 (Study of FF-10502-01 in Patients With Advanced Solid Tumors and
Experimental
Matched Synonyms: … 4-[[(1S)-1-(4,8-dichloro-1-oxo-2-phenylisoquinolin-3-yl)ethyl]amino]-8H-pyrido[2,3-d]pyrimidin-5-one …
Investigational
Matched Synonyms: … 5h-(1,3)dioxolo(4',5':5,6)indeno(1,2-c)isoquinoline-5,12(6h)-dione, 2,3-dimethoxy-6-(3-(4-morpholinyl …
Matched Salts name: … Indotecan hydrochloride
Experimental
Matched Synonyms: … N,N-Bis(3-(D-gluconamido)propyl)deoxycholamide ... D-Gluconamide, N,N'-((((3alpha,5beta,12alpha)-3,12-dihydroxy-24-oxocholan-24-yl)imino)di-3,1-propanediyl ... N,N'-((((3alpha,5beta,12alpha)-3,12-Dihydroxy-24-oxocholan-24-yl)imino)di-3,1-propandiyl)bis-D-gluconamide …
Matched Name: … N,N-Bis(3-(D-gluconamido)propyl)deoxycholamide …
Matched Iupac: … (2R,3S,4R,5R)-N-{3-[(4R)-4-[(1R,3aS,3bR,5aR,7R,9aS,9bS,11S,11aR)-7,11-dihydroxy-9a,11a-dimethyl-hexadecahydro ... -1H-cyclopenta[a]phenanthren-1-yl]-N-{3-[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanamido]propyl}pentanamido …
Experimental
Matched Name: … (3s)-3-Amino-1-(Cyclopropylamino)Heptane-2,2-Diol …
Matched Iupac: … (3S)-3-amino-1-(cyclopropylamino)heptane-2,2-diol …
Experimental
Matched Name: … N-(5-Cyclopropyl-1h-Pyrazol-3-Yl)Benzamide …
Matched Iupac: … N-(3-cyclopropyl-1H-pyrazol-5-yl)benzamide …
Constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias. [PubChem]
Experimental
Matched Name: … (3-Carboxy-2-(R)-Hydroxy-Propyl)-Trimethyl-Ammonium …
Matched Iupac: … [(2R)-3-carboxy-2-hydroxypropyl]trimethylazanium …
Matched Description: … Constituent of striated muscle and liver. ... It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias …
Experimental
Matched Name: … 1-Monohexanoyl-2-Hydroxy-Sn-Glycero-3-Phosphate …
Matched Iupac: … [(2S)-3-(hexanoyloxy)-2-hydroxypropoxy]phosphonic acid
Experimental
Matched Name: … 5-(3,3-Dihydroxypropeny)-3-Methoxy-Benzene-1,2-Diol …
Matched Iupac: … 5-[(1E)-3,3-dihydroxyprop-1-en-1-yl]-3-methoxybenzene-1,2-diol …
Experimental
Matched Name: … 1-ACETYL-2-LYSO-SN-GLYCERO-3-PHOSPHOETHANOLAMINE …
Matched Iupac: … [(2S)-3-(acetyloxy)-2-hydroxypropoxy](2-azaniumylethoxy)phosphinic acid
Experimental
Matched Name: … N-(3-chlorobenzyl)-1-(4-methylpentanoyl)-L-prolinamide …
Matched Iupac: … (2S)-N-[(3-chlorophenyl)methyl]-1-(4-methylpentanoyl)pyrrolidine-2-carboxamide …
N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-l-prolinamide is a solid. This compound belongs to the alpha amino acid amides. These are amide derivatives of alpha amino acids. This medication targets the protein prothrombin.
Experimental
Matched Name: … N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-L-prolinamide …
Matched Iupac: … (2S)-N-[(4-carbamimidoylphenyl)methyl]-1-(3-phenylpropanoyl)pyrrolidine-2-carboxamide …
Matched Description: … These are amide derivatives of alpha amino acids. This medication targets the protein prothrombin. ... This compound belongs to the alpha amino acid amides. ... N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-l-prolinamide is a solid. …
Displaying drugs 5001 - 5025 of 5846 in total